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Telisotuzumab Vedotin Is Active in MET-Overexpressing Non-Squamous NSCLC Available to Purchase
June 18, 2024
Major Finding: In the phase 2 LUMINOSITY trial of telisotuzumab vedotin monotherapy in previously treated advanced EGFR-wildtype non-squamous NSCLC, the overall response rate was 28.6%.
Concept: A trend toward a higher overall response rate was observed in patients whose tumors had high MET expression.
Impact: Telisotuzumab vedotin may benefit a patient population for whom no MET-targeted therapies are currently available.
DOI:https://doi.org/10.1158/2159-8290.CD-RW2024-086
Article Type:
Research Watch
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