Alveolar Intermediary Cells Act As Progenitors for <em>KRAS</em>-Mutant Lung Cancer

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March 14, 2024

Major Finding: KRT8⁺ alveolar intermediary cells appear early and act as progenitors for KRAS-mutant lung adenocarcinoma.

Concept: KRT8⁺alveolar intermediary cells demonstrate reduced differentiation and increased plasticity.

Impact: This insight into lung cancer development reveals potential prevention and therapeutic targets.

DOI:https://doi.org/10.1158/2159-8290.CD-RW2024-042

Article Type: Research Watch

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Alveolar Intermediary Cells Act As Progenitors for KRAS-Mutant Lung Cancer