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Lung Adenocarcinoma Must Tolerate Myc for Neuroendocrine Transformation
February 15, 2024
Major Finding: A mouse model reveals the steps required for histological transformation of lung adenocarcinoma (LUAD).
Concept: The intolerance of Myc as an oncogenic driver in LUAD is a barrier to histological transformation.
Impact: This has implications for detecting or preventing the conversion of LUAD to an aggressive subtype.
DOI:https://doi.org/10.1158/2159-8290.CD-RW2024-028
Article Type:
Research Watch
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