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Lung Adenocarcinoma Must Tolerate Myc for Neuroendocrine Transformation

February 15, 2024

Major Finding: A mouse model reveals the steps required for histological transformation of lung adenocarcinoma (LUAD).

Concept: The intolerance of Myc as an oncogenic driver in LUAD is a barrier to histological transformation.

Impact: This has implications for detecting or preventing the conversion of LUAD to an aggressive subtype. 

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