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Stem-Immunity Hubs Are Associated with Immunotherapy Response in Lung Cancer

April 9, 2024

Major Finding: Stem-immunity hubs are associated with response to immunotherapy in non–small cell lung cancer.

Concept: These CXCL10/CXCL11-expressing immunity hubs are enriched for TCF7+CD8+ T cells and CCL19.

Impact: This immune cell spatial organization could be leveraged to predict or enhance immunotherapy response.

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