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Relative Scarcity of Disseminated Tumor Cells Enables Immune Evasion

February 1, 2024

Major Finding: The relative scarcity of disseminated tumor cells enables their evasion of antitumor immunity.

Concept: Increased T-cell effector:target ratios promote tumor cell clearance in an MHC-independent manner.

Impact: Therapies that increase tumor-specific T-cell abundance may eliminate DTCs and prevent recurrence.

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