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Journal Articles

A melanoma brain metastasis CTC signature and CTC:B cell clusters associate with secondary liver metastasis: a melanoma brain-liver metastasis axis

Tetiana Y Bowley, Mireya C Ortiz, Irina V Lagutina, Mara P. Steinkamp, Bridget N. Fahy, Bernard Tawfik, Moises Harari-Turquie, Dario Marchetti
Journal: Cancer Research Communications
Cancer Research Communications (2025)
https://doi.org/10.1158/2767-9764.CRC-24-0498
Published: 20 January 2025
View article titled, A melanoma brain metastasis CTC signature and CTC:B cell clusters associate with secondary liver metastasis: a melanoma brain-liver metastasis axis
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Includes: Supplementary data
Journal Articles

Loss of NF1 accelerates uveal and intra-dermal melanoma tumorigenesis and oncogenic GNAQ transforms Schwann cells

Anne Nathalie Longakit, Oscar Urtatiz, Amy Luty, Christina Zhang, Chloe Hess, Alyssa Yoo, Hannah Bourget, Catherine D Van Raamsdonk
Journal: Cancer Research Communications
Cancer Research Communications (2025)
https://doi.org/10.1158/2767-9764.CRC-24-0386
Published: 13 January 2025
View article titled, Loss of NF1 accelerates uveal and intra-dermal melanoma tumorigenesis and oncogenic GNAQ transforms Schwann cells
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Includes: Supplementary data
Journal Articles

Targeting pancreatic cancer cell stemness by blocking fibronectin-binding integrins on cancer-associated fibroblasts

Chengsheng Wu, Tami von Schalscha, Diva Sansanwal, Chen Qian, Qinlin Jiang, Ryan M. Shepard, Hiromi I. Wettersten, Stephen J. McCormack, Sara M. Weis, David A. Cheresh
Journal: Cancer Research Communications
Cancer Research Communications (2025)
https://doi.org/10.1158/2767-9764.CRC-24-0491
Published: 09 January 2025
View article titled, Targeting pancreatic cancer cell stemness by blocking fibronectin-binding integrins on cancer-associated fibroblasts
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Includes: Supplementary data
Journal Articles

Kinetics of Nirogacestat-Mediated Increases in B-cell Maturation Antigen on Plasma Cells Inform Therapeutic Combinations in Multiple Myeloma

Todd Shearer, Melissa Comstock, Rex L. Williams, Jr, Mark C. Johnson, Ewa Cendrowicz, Cathrine Leonowens, Margaret Smith, Todd M. Baughman, Caroline J. Breitbach, Shinta Cheng, Damian J. Green
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (12): 3114–3123.
https://doi.org/10.1158/2767-9764.CRC-24-0075
Published: 11 December 2024
View article titled, Kinetics of Nirogacestat-Mediated Increases in B-cell Maturation Antigen on Plasma Cells Inform Therapeutic Combinations in Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines

Anne E. Dodson, Sol Shenker, Pamela Sullivan, Sumeet U. Nayak, Chris Middleton, Michael McGuire, Edmond Chipumuro, Yuji Mishina, Erica R. Tobin, Louise Cadzow, Andrew A. Wylie, Dipen Sangurdekar
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (12): 3084–3098.
https://doi.org/10.1158/2767-9764.CRC-24-0316
Published: 06 December 2024
View article titled, Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines
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Includes: Supplementary data
Journal Articles

ETx-22, a Novel Nectin-4–Directed Antibody–Drug Conjugate, Demonstrates Safety and Potent Antitumor Activity in Low-Nectin-4–Expressing Tumors

Marc Lopez, Emerence Crompot, Emmanuelle Josselin, Anne Farina, Marion Rubis, Remy Castellano, Joanna Fares, Maria Wehbe, Yves Collette, Emmanuelle Charafe, Stéphanie Blanchin, François Romagne, Anikó Pálfi, Torsten Hechler, Andreas Pahl, Hatem A. Azim, Jr, Florence Lhospice, Emilie Mamessier, François Bertucci, Jack Elands, Xavier Préville, Daniel Olive
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (11): 2998–3012.
https://doi.org/10.1158/2767-9764.CRC-24-0176
Published: 22 November 2024
View article titled, ETx-22, a Novel Nectin-4–Directed Antibody–Drug Conjugate, Demonstrates Safety and Potent Antitumor Activity in Low-Nectin-4–Expressing Tumors
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Includes: Supplementary data
Journal Articles

Mathematical Modeling Unveils Optimization Strategies for Targeted Radionuclide Therapy of Blood Cancers

Maxim Kuznetsov, Vikram Adhikarla, Enrico Caserta, Xiuli Wang, John E. Shively, Flavia Pichiorri, Russell C. Rockne
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (11): 2955–2967.
https://doi.org/10.1158/2767-9764.CRC-24-0306
Published: 14 November 2024
View article titled, Mathematical Modeling Unveils Optimization Strategies for Targeted Radionuclide Therapy of Blood Cancers
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Includes: Supplementary data
Journal Articles

Evaluation of Copanlisib in Combination with Eribulin in Triple-negative Breast Cancer Patient-derived Xenograft Models

Zhanfang Guo, Jingqin Luo, R. Jay Mashl, Jeremy Hoog, Piyush Maiti, Nikki Fettig, Sherri R. Davies, Rebecca Aft, Jason M. Held, Ramaswamy Govindan, Li Ding, Shunqiang Li, Cornelius von Morze, Gerburg M. Wulf, Kooresh I. Shoghi, Cynthia X. Ma
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (6): 1430–1440.
https://doi.org/10.1158/2767-9764.CRC-24-0047
Published: 05 June 2024
View article titled, Evaluation of Copanlisib in Combination with Eribulin in Triple-negative Breast Cancer Patient-derived Xenograft Models
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Includes: Supplementary data
Journal Articles

Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects

Alexandria P. Eiken, Audrey L. Smith, Sydney A. Skupa, Elizabeth Schmitz, Sandeep Rana, Sarbjit Singh, Siddhartha Kumar, Jayapal Reddy Mallareddy, Aguirre A de Cubas, Akshay Krishna, Achyuth Kalluchi, M. Jordan Rowley, Christopher R. D'Angelo, Matthew A. Lunning, R. Gregory Bociek, Julie M. Vose, Amarnath Natarajan, Dalia El-Gamal
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (5): 1328–1343.
https://doi.org/10.1158/2767-9764.CRC-24-0071
Published: 22 May 2024
View article titled, Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects
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Includes: Supplementary data
Journal Articles

Exercise-induced β2-adrenergic Receptor Activation Enhances the Antileukemic Activity of Expanded γδ T-Cells via DNAM-1 Upregulation and PVR/Nectin-2 Recognition

Forrest L. Baker, Kyle A. Smith, Preetesh L. Mylabathula, Tiffany M. Zúñiga, Douglass M. Diak, Helena Batatinha, Grace M. Niemiro, Michael D. Seckeler, Charles R. Pedlar, Daniel P. O'Connor, Jamie Colombo, Emmanuel Katsanis, Richard J. Simpson
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (5): 1253–1267.
https://doi.org/10.1158/2767-9764.CRC-23-0570
Published: 13 May 2024
View article titled, Exercise-induced β2-adrenergic Receptor Activation Enhances the Antileukemic Activity of Expanded γδ T-Cells via DNAM-1 Upregulation and PVR/Nectin-2 Recognition
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Includes: Supplementary data
Journal Articles

Modeling Myeloma Dissemination In Vitro with hMSC-interacting Subpopulations of INA-6 Cells and Their Aggregation/Detachment Dynamics

Martin Kuric, Susanne Beck, Doris Schneider, Wyonna Rindt, Marietheres Evers, Jutta Meißner-Weigl, Sabine Zeck, Melanie Krug, Marietta Herrmann, Tanja Nicole Hartmann, Ellen Leich, Maximilian Rudert, Denitsa Docheva, Anja Seckinger, Dirk Hose, Franziska Jundt, Regina Ebert
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (4): 1150–1164.
https://doi.org/10.1158/2767-9764.CRC-23-0411
Published: 29 April 2024
View article titled, Modeling Myeloma Dissemination <em>In Vitro</em> with hMSC-interacting Subpopulations of INA-6 Cells and Their Aggregation/Detachment Dynamics
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Includes: Multimedia, Supplementary data
Journal Articles

Epithelial Expressed B7-H4 Drives Differential Immunotherapy Response in Murine and Human Breast Cancer

Elizabeth C. Wescott, Xiaopeng Sun, Paula Gonzalez-Ericsson, Ann Hanna, Brandie C. Taylor, Violeta Sanchez, Juliana Bronzini, Susan R. Opalenik, Melinda E. Sanders, Julia Wulfkuhle, Rosa I. Gallagher, Henry Gomez, Claudine Isaacs, Vijaya Bharti, John T. Wilson, Tarah J. Ballinger, Cesar A. Santa-Maria, Payal D. Shah, Elizabeth C. Dees, Brian D. Lehmann, Vandana G. Abramson, Gillian L. Hirst, Lamorna Brown Swigart, Laura J. van ˈt Veer, Laura J. Esserman, Emanuel F. Petricoin, Jennifer A. Pietenpol, Justin M. Balko
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (4): 1120–1134.
https://doi.org/10.1158/2767-9764.CRC-23-0468
Published: 24 April 2024
View article titled, Epithelial Expressed B7-H4 Drives Differential Immunotherapy Response in Murine and Human Breast Cancer
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Includes: Supplementary data
Journal Articles

Overcoming Xenoantigen Immunity to Enable Cellular Tracking and Gene Regulation with Immune-competent “NoGlow” Mice

Timothy N. Trotter, Andrea Wilson, Jason McBane, Carina E. Dagotto, Xiao-Yi Yang, Jun-Ping Wei, Gangjun Lei, Hannah Thrash, Joshua C. Snyder, Herbert Kim Lyerly, Zachary C. Hartman
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (4): 1050–1062.
https://doi.org/10.1158/2767-9764.CRC-24-0062
Published: 09 April 2024
View article titled, Overcoming Xenoantigen Immunity to Enable Cellular Tracking and Gene Regulation with Immune-competent “NoGlow” Mice
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Includes: Supplementary data
Journal Articles

Activity of the Ubiquitin-activating Enzyme Inhibitor TAK-243 in Adrenocortical Carcinoma Cell Lines, Patient-derived Organoids, and Murine Xenografts

Yasuhiro Arakawa, Ukhyun Jo, Suresh Kumar, Nai-Yun Sun, Fathi Elloumi, Anish Thomas, Nitin Roper, Diana Grace Varghese, Naoko Takebe, Xiaohu Zhang, Michele Ceribelli, David O. Holland, Erin Beck, Zina Itkin, Crystal McKnight, Kelli M. Wilson, Jameson Travers, Carleen Klumpp-Thomas, Craig J. Thomas, Chuong D. Hoang, Jonathan M. Hernandez, Jaydira Del Rivero, Yves Pommier
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (3): 834–848.
https://doi.org/10.1158/2767-9764.CRC-24-0085
Published: 19 March 2024
View article titled, Activity of the Ubiquitin-activating Enzyme Inhibitor TAK-243 in Adrenocortical Carcinoma Cell Lines, Patient-derived Organoids, and Murine Xenografts
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Includes: Supplementary data
Journal Articles

Establishment and Characterization of an Epstein-Barr Virus–positive Cell Line from a Non-keratinizing Differentiated Primary Nasopharyngeal Carcinoma

Annie Wai Yeeng Chai, Shi Mun Yee, Hui Mei Lee, Norazlin Abdul Aziz, Pei San Yee, Marini Marzuki, Ka Wo Wong, Alan K.S. Chiang, Larry Ka-Yue Chow, Wei Dai, Teng Fei Liu, Lu Ping Tan, Alan Soo Beng Khoo, Kwok Wai Lo, Paul V.H. Lim, Pathmanathan Rajadurai, Howard Lightfoot, Syd Barthorpe, Mathew J. Garnett, Sok Ching Cheong
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (3): 645–659.
https://doi.org/10.1158/2767-9764.CRC-23-0341
Published: 04 March 2024
View article titled, Establishment and Characterization of an Epstein-Barr Virus–positive Cell Line from a Non-keratinizing Differentiated Primary Nasopharyngeal Carcinoma
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Includes: Supplementary data
Journal Articles

Cancer-associated Fibroblast–specific Expression of the Matricellular Protein CCN1 Coordinates Neovascularization and Stroma Deposition in Melanoma Metastasis

James Hutchenreuther, John Nguyen, Katherine Quesnel, Krista M. Vincent, Louis Petitjean, Sophia Bourgeois, Mark Boyd, George Bou-Gharios, Lynne-Marie Postovit, Andrew Leask
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (2): 556–570.
https://doi.org/10.1158/2767-9764.CRC-23-0571
Published: 27 February 2024
View article titled, Cancer-associated Fibroblast–specific Expression of the Matricellular Protein CCN1 Coordinates Neovascularization and Stroma Deposition in Melanoma Metastasis
Open the PDF for Cancer-associated Fibroblast–specific Expression of the Matricellular Protein CCN1 Coordinates Neovascularization and Stroma Deposition in Melanoma Metastasis in another window
Includes: Multimedia, Supplementary data
Journal Articles

Functional Heterogeneity in MET Pathway Activation in PDX Models of Osimertinib-resistant EGFR-driven Lung Cancer

Nitin Roper, Rajaa El Meskini, Tapan Maity, Devon Atkinson, Amanda Day, Nathan Pate, Constance M. Cultraro, Svetlana Pack, Valerie Zgonc, Zoe Weaver Ohler, Udayan Guha
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (2): 337–348.
https://doi.org/10.1158/2767-9764.CRC-23-0321
Published: 08 February 2024
View article titled, Functional Heterogeneity in MET Pathway Activation in PDX Models of Osimertinib-resistant EGFR-driven Lung Cancer
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Includes: Supplementary data
Journal Articles

Dietary Folate and Cofactors Accelerate Age-dependent p16 Epimutation to Promote Intestinal Tumorigenesis

Li Yang, Robert C. Peery, Leah M. Farmer, Xia Gao, Yiqun Zhang, Chad J. Creighton, Lanjing Zhang, Lanlan Shen
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (1): 164–169.
https://doi.org/10.1158/2767-9764.CRC-23-0356
Published: 19 January 2024
View article titled, Dietary Folate and Cofactors Accelerate Age-dependent <em>p16</em> Epimutation to Promote Intestinal Tumorigenesis
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Includes: Supplementary data
Journal Articles

Monitoring Glucocorticoid Receptor in Plasma-derived Extracellular Vesicles as a Marker of Resistance to Androgen Receptor Signaling Inhibition in Prostate Cancer

Emanuela Gentile, Andrew W. Hahn, Jian H. Song, Anh Hoang, Peter D. A. Shepherd, Sumankalai Ramachandran, Nora M. Navone, Eleni Efstathiou, Mark Titus, Paul G. Corn, Sue-Hwa Lin, Christopher J. Logothetis, Theocharis Panaretakis
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (12): 2531–2543.
https://doi.org/10.1158/2767-9764.CRC-23-0362
Published: 13 December 2023
View article titled, Monitoring Glucocorticoid Receptor in Plasma-derived Extracellular Vesicles as a Marker of Resistance to Androgen Receptor Signaling Inhibition in Prostate Cancer
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Includes: Supplementary data
Journal Articles

Integrin-αvβ3 is a Therapeutically Targetable Fundamental Factor in Medulloblastoma Tumorigenicity and Radioresistance

William Echavidre, Jérôme Durivault, Célia Gotorbe, Thays Blanchard, Marina Pagnuzzi, Valérie Vial, Florian Raes, Alexis Broisat, Rémy Villeneuve, Régis Amblard, Nicolas Garnier, Cécile Ortholan, Marc Faraggi, Benjamin Serrano, Vincent Picco, Christopher Montemagno
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (12): 2483–2496.
https://doi.org/10.1158/2767-9764.CRC-23-0298
Published: 07 December 2023
View article titled, Integrin-αvβ3 is a Therapeutically Targetable Fundamental Factor in Medulloblastoma Tumorigenicity and Radioresistance
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Includes: Supplementary data