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Journal Articles

Clinical Proteomics Reveals Vulnerabilities in Noninvasive Breast Ductal Carcinoma and Drives Personalized Treatment Strategies

Georgia Mitsa, Livia Florianova, Josiane Lafleur, Adriana Aguilar-Mahecha, Rene P. Zahedi, Sonia V. del Rincon, Mark Basik, Christoph H. Borchers, Gerald Batist
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (1): 138–149.
https://doi.org/10.1158/2767-9764.CRC-24-0287
Published: 23 January 2025
View article titled, Clinical Proteomics Reveals Vulnerabilities in Noninvasive Breast Ductal Carcinoma and Drives Personalized Treatment Strategies
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Includes: Supplementary data
Journal Articles

A melanoma brain metastasis CTC signature and CTC:B cell clusters associate with secondary liver metastasis: a melanoma brain-liver metastasis axis

Tetiana Y Bowley, Mireya C Ortiz, Irina V Lagutina, Mara P. Steinkamp, Bridget N. Fahy, Bernard Tawfik, Moises Harari-Turquie, Dario Marchetti
Journal: Cancer Research Communications
Cancer Research Communications (2025)
https://doi.org/10.1158/2767-9764.CRC-24-0498
Published: 20 January 2025
View article titled, A melanoma brain metastasis CTC signature and CTC:B cell clusters associate with secondary liver metastasis: a melanoma brain-liver metastasis axis
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Includes: Supplementary data
Journal Articles

Single-Cell RNA Sequencing before and after Light Chain Escape Reveals Intrapatient Multiple Myeloma Subpopulations with Divergent Osteolytic Gene Expression

Denis Ohlstrom, Zachary J. Walker, Abhishek Pandey, Lorraine N. Davis, Krysta L. Engel, Zenggang Pan, Peter A. Forsberg, Tomer M. Mark, Austin E. Gillen, Daniel W. Sherbenou
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (1): 106–118.
https://doi.org/10.1158/2767-9764.CRC-24-0170
Published: 16 January 2025
View article titled, Single-Cell RNA Sequencing before and after Light Chain Escape Reveals Intrapatient Multiple Myeloma Subpopulations with Divergent Osteolytic Gene Expression
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Includes: Supplementary data
Journal Articles

Ternary complex components responsible for rapid LDL internalization as biomarkers for breast cancer associated with proliferation and early recurrence.

Elizabeth S McDonald, Tien-Chi Pan, Dhruv K Pant, Melissa A Troester, Andrew V. Kossenkov, David A. Mankoff, Robert H. Mach, Lewis A Chodosh
Journal: Cancer Research Communications
Cancer Research Communications (2025)
https://doi.org/10.1158/2767-9764.CRC-23-0562
Published: 13 January 2025
View article titled, Ternary complex components responsible for rapid LDL internalization as biomarkers for breast cancer associated with proliferation and early recurrence.
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Includes: Supplementary data
Journal Articles

Loss of NF1 accelerates uveal and intra-dermal melanoma tumorigenesis and oncogenic GNAQ transforms Schwann cells

Anne Nathalie Longakit, Oscar Urtatiz, Amy Luty, Christina Zhang, Chloe Hess, Alyssa Yoo, Hannah Bourget, Catherine D Van Raamsdonk
Journal: Cancer Research Communications
Cancer Research Communications (2025)
https://doi.org/10.1158/2767-9764.CRC-24-0386
Published: 13 January 2025
View article titled, Loss of NF1 accelerates uveal and intra-dermal melanoma tumorigenesis and oncogenic GNAQ transforms Schwann cells
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Includes: Supplementary data
Journal Articles

Clonal Hematopoiesis of Indeterminate Potential and its Association with Treatment Outcomes and Adverse Events in Patients with Solid Tumors

Tharani Krishnan, Joao Paulo Solar Vasconcelos, Emma Titmuss, Robert J. Vanner, David F. Schaeffer, Aly Karsan, Howard Lim, Cheryl Ho, Sharlene Gill, Stephen Yip, Stephen K. Chia, Hagen F. Kennecke, Derek J. Jonker, Eric X. Chen, Daniel J. Renouf, Chris J. O’Callaghan, Jonathan M. Loree
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (1): 66–73.
https://doi.org/10.1158/2767-9764.CRC-24-0522
Published: 09 January 2025
View article titled, Clonal Hematopoiesis of Indeterminate Potential and its Association with Treatment Outcomes and Adverse Events in Patients with Solid Tumors
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Includes: Supplementary data
Journal Articles

Targeting pancreatic cancer cell stemness by blocking fibronectin-binding integrins on cancer-associated fibroblasts

Chengsheng Wu, Tami von Schalscha, Diva Sansanwal, Chen Qian, Qinlin Jiang, Ryan M. Shepard, Hiromi I. Wettersten, Stephen J. McCormack, Sara M. Weis, David A. Cheresh
Journal: Cancer Research Communications
Cancer Research Communications (2025)
https://doi.org/10.1158/2767-9764.CRC-24-0491
Published: 09 January 2025
View article titled, Targeting pancreatic cancer cell stemness by blocking fibronectin-binding integrins on cancer-associated fibroblasts
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Includes: Supplementary data
Journal Articles

Serially quantifying TERT rearrangement breakpoints in circulating tumor DNA enables minimal residual disease monitoring in patients with neuroblastoma

Jan F. Hollander, Annabell Szymansky, Jasmin Wünschel, Kathy Astrahantseff, Carolina Rosswog, Anne Thorwarth, Theresa M. Thole-Kliesch, Rocío Chamorro Gonzalez, Patrick Hundsdörfer, Kathrin Hauptmann, Karin Schmelz, Dennis Gürgen, Julian M.M. Rogasch, Anton G. Henssen, Matthias Fischer, Johannes H. Schulte, Cornelia Eckert, Angelika Eggert, Marco Lodrini, Hedwig E. Deubzer
Journal: Cancer Research Communications
Cancer Research Communications (2025)
https://doi.org/10.1158/2767-9764.CRC-24-0569
Published: 06 January 2025
View article titled, Serially quantifying <em>TERT</em> rearrangement breakpoints in circulating tumor DNA enables minimal residual disease monitoring in patients with neuroblastoma
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Includes: Supplementary data
Journal Articles

A cost-effective two-step approach for multi-cancer early detection in high-risk populations

Shuaipeng Geng, Shiyong Li, Wei Wu, Yinyin Chang, Mao Mao
Journal: Cancer Research Communications
Cancer Research Communications (2024)
https://doi.org/10.1158/2767-9764.CRC-24-0508
Published: 31 December 2024
View article titled, A cost-effective two-step approach for multi-cancer early detection in high-risk populations
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Includes: Supplementary data
Journal Articles

Tumor Expression of CD83 Reduces Glioma Progression and Is Associated with Reduced Immunosuppression

Malcolm F. McDonald, Rachel Naomi Curry, Isabella O’Reilly, Brittney Lozzi, Alexis Cervantes, Zhung-Fu Lee, Anna Rosenbaum, Peihao He, Carrie Mohila, Arif O. Harmanci, Akdes Serin Harmanci, Benjamin Deneen, Ganesh Rao
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (12): 3209–3223.
https://doi.org/10.1158/2767-9764.CRC-24-0281
Published: 30 December 2024
View article titled, Tumor Expression of CD83 Reduces Glioma Progression and Is Associated with Reduced Immunosuppression
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Includes: Supplementary data
Journal Articles

Identification of ncRNA Biomarkers in Non–Small Cell Lung Cancer to Address Racial Disparities

Lu Gao, Pushpa Dhilipkannah, Feng Jiang
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (12): 3201–3208.
https://doi.org/10.1158/2767-9764.CRC-24-0262
Published: 27 December 2024
View article titled, Identification of ncRNA Biomarkers in Non–Small Cell Lung Cancer to Address Racial Disparities
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Includes: Supplementary data
Journal Articles

DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways

Zhaoxiang Cai, Rebecca C. Poulos, Adel Aref, Phillip J. Robinson, Roger R. Reddel, Qing Zhong
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (12): 3151–3164.
https://doi.org/10.1158/2767-9764.CRC-24-0285
Published: 18 December 2024
View article titled, DeePathNet: A Transformer-Based Deep Learning Model Integrating Multiomic Data with Cancer Pathways
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Includes: Supplementary data
Journal Articles

SpliceMutr Enables Pan-Cancer Analysis of Splicing-Derived Neoantigen Burden in Tumors

Theron Palmer, Michael D. Kessler, Xiaoshan M. Shao, Archana Balan, Mark Yarchoan, Neeha Zaidi, Tamara Y. Lopez-Vidal, Ali M. Saeed, Jessica Gore, Nilofer S. Azad, Elizabeth M. Jaffee, Alexander V. Favorov, Valsamo Anagnostou, Rachel Karchin, Daria A. Gaykalova, Elana J. Fertig, Ludmila Danilova
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (12): 3137–3150.
https://doi.org/10.1158/2767-9764.CRC-23-0309
Published: 16 December 2024
View article titled, SpliceMutr Enables Pan-Cancer Analysis of Splicing-Derived Neoantigen Burden in Tumors
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Includes: Supplementary data
Journal Articles

Kinetics of Nirogacestat-Mediated Increases in B-cell Maturation Antigen on Plasma Cells Inform Therapeutic Combinations in Multiple Myeloma

Todd Shearer, Melissa Comstock, Rex L. Williams, Jr, Mark C. Johnson, Ewa Cendrowicz, Cathrine Leonowens, Margaret Smith, Todd M. Baughman, Caroline J. Breitbach, Shinta Cheng, Damian J. Green
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (12): 3114–3123.
https://doi.org/10.1158/2767-9764.CRC-24-0075
Published: 11 December 2024
View article titled, Kinetics of Nirogacestat-Mediated Increases in B-cell Maturation Antigen on Plasma Cells Inform Therapeutic Combinations in Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines

Anne E. Dodson, Sol Shenker, Pamela Sullivan, Sumeet U. Nayak, Chris Middleton, Michael McGuire, Edmond Chipumuro, Yuji Mishina, Erica R. Tobin, Louise Cadzow, Andrew A. Wylie, Dipen Sangurdekar
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (12): 3084–3098.
https://doi.org/10.1158/2767-9764.CRC-24-0316
Published: 06 December 2024
View article titled, Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines
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Includes: Supplementary data
Journal Articles

Single-Cell Analysis of Bone Marrow CD8+ T Cells in Myeloid Neoplasms Reveals Pathways Associated with Disease Progression and Response to Treatment with Azacitidine

Athanasios Tasis, Nikos E. Papaioannou, Maria Grigoriou, Nikolaos Paschalidis, Catherine Loukogiannaki, Anastasia Filia, Kyriaki Katsiki, Eleftheria Lamprianidou, Vasileios Papadopoulos, Christina Maria Rimpa, Antonios Chatzigeorgiou, Ioannis Kourtzelis, Petroula Gerasimou, Ioannis Kyprianou, Paul Costeas, Panagiotis Liakopoulos, Konstantinos Liapis, Petros Kolovos, Triantafyllos Chavakis, Themis Alissafi, Ioannis Kotsianidis, Ioannis Mitroulis
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (12): 3067–3083.
https://doi.org/10.1158/2767-9764.CRC-24-0310
Published: 04 December 2024
View article titled, Single-Cell Analysis of Bone Marrow CD8<sup>+</sup> T Cells in Myeloid Neoplasms Reveals Pathways Associated with Disease Progression and Response to Treatment with Azacitidine
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Includes: Supplementary data
Journal Articles

Dynamic Evolution of Fibroblasts Revealed by Single-Cell RNA Sequencing of Human Pancreatic Cancer

Slavica Dimitrieva, Jon M. Harrison, Jonathan Chang, Michelle Piquet, Mari Mino-Kenudson, Millicent Gabriel, Vivek Sagar, Heiko Horn, Kasper Lage, Julie Kim, Gang Li, Shaobu Weng, Cynthia Harris, Anupriya S. Kulkarni, David T. Ting, Motaz Qadan, Peter J. Fagenholz, Cristina R. Ferrone, Angelo L. Grauel, Tyler Laszewski, Alina Raza, Markus Riester, Tim Somerville, Joel P. Wagner, Glenn Dranoff, Jeffrey A. Engelman, Audrey Kauffmann, Rebecca Leary, Andrew L. Warshaw, Keith D. Lillemoe, Carlos Fernández-del Castillo, David A. Ruddy, Andrew S. Liss, Viviana Cremasco
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (12): 3049–3066.
https://doi.org/10.1158/2767-9764.CRC-23-0489
Published: 02 December 2024
View article titled, Dynamic Evolution of Fibroblasts Revealed by Single-Cell RNA Sequencing of Human Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

Mathematical Modeling Unveils Optimization Strategies for Targeted Radionuclide Therapy of Blood Cancers

Maxim Kuznetsov, Vikram Adhikarla, Enrico Caserta, Xiuli Wang, John E. Shively, Flavia Pichiorri, Russell C. Rockne
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (11): 2955–2967.
https://doi.org/10.1158/2767-9764.CRC-24-0306
Published: 14 November 2024
View article titled, Mathematical Modeling Unveils Optimization Strategies for Targeted Radionuclide Therapy of Blood Cancers
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Includes: Supplementary data
Journal Articles

Transcriptome Deconvolution Reveals Absence of Cancer Cell Expression Signature in Immune Checkpoint Blockade Response

Yu Amanda Guo, Tanmay Kulshrestha, Mei Mei Chang, Irfahan Kassam, Egor Revkov, Simone Rizzetto, Aaron C. Tan, Daniel S.W. Tan, Iain Beehuat Tan, Anders J. Skanderup
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (6): 1581–1596.
https://doi.org/10.1158/2767-9764.CRC-23-0442
Published: 26 June 2024
View article titled, Transcriptome Deconvolution Reveals Absence of Cancer Cell Expression Signature in Immune Checkpoint Blockade Response
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Includes: Supplementary data
Journal Articles

HDAC6 Inhibition Releases HR23B to Activate Proteasomes, Expand the Tumor Immunopeptidome and Amplify T-cell Antimyeloma Activity

Priyanka S. Rana, James J. Ignatz-Hoover, Byung-Gyu Kim, Ehsan Malek, Yuriy Federov, Drew Adams, Timothy Chan, James J. Driscoll
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (6): 1517–1532.
https://doi.org/10.1158/2767-9764.CRC-23-0528
Published: 18 June 2024
View article titled, HDAC6 Inhibition Releases HR23B to Activate Proteasomes, Expand the Tumor Immunopeptidome and Amplify T-cell Antimyeloma Activity
Open the PDF for HDAC6 Inhibition Releases HR23B to Activate Proteasomes, Expand the Tumor Immunopeptidome and Amplify T-cell Antimyeloma Activity in another window
Includes: Supplementary data