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Journal Articles

A Phase 1b/2 Study of TP-0903 and Decitabine Targeting Mutant TP53 and/or Complex Karyotype in Patients with Untreated Acute Myeloid Leukemia ≥Age 60 Years

Open Access
Eric D. Eisenmann, Ronan Swords, Ying Huang, Shelley Orwick, Daelynn Buelow, Nicole Abbott, Mitch Phelps, Joshua Zeidner, Matthew C. Foster, Tara L. Lin, Maria R. Baer, Yazan F. Madanat, Tibor Kovacsovics, Robert Redner, Zeina Al-Mansour, Bhavana Bhatnagar, Mona Stefanos, Molly Martycz, Franchesca Druggan, Timothy L. Chen, Ashley O. Yocum, Uma Borate, Brian J. Druker, Amy Burd, Ross L. Levine, John C. Byrd, Sharyn D. Baker, Alice S. Mims
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (7): 1129–1139.
https://doi.org/10.1158/2767-9764.CRC-25-0091
Published: 14 July 2025
View articletitled, A Phase 1b/2 Study of TP-0903 and Decitabine Targeting Mutant TP53 and/or Complex Karyotype in Patients with Untreated Acute Myeloid Leukemia ≥Age 60 Years
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Includes: Supplementary data
Journal Articles

Phase I First-in-Human Study of TRK-950, an IgG1 Antibody Specific to CAPRIN-1, in Patients with Advanced Solid Tumors

Open Access
Philippe A. Cassier, Mitesh J. Borad, Sunil Sharma, Bertrand Dubois, Christophe Caux, Fumiyoshi Okano, Daniel D. Von Hoff, Jean-Yves Blay
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (7): 1119–1128.
https://doi.org/10.1158/2767-9764.CRC-25-0123
Published: 11 July 2025
View articletitled, Phase I First-in-Human Study of TRK-950, an IgG1 Antibody Specific to CAPRIN-1, in Patients with Advanced Solid Tumors
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Includes: Supplementary data
Journal Articles

Plasma Cell-Free Human Papillomavirus (HPV) DNA and Oral Gargle HPV DNA in Patients with HPV-related Oropharyngeal Cancer Treated with Radiotherapy

Open Access
Michelle Echevarria, Robin Park, Jimmy J. Caudell, Youngchul Kim, George Q. Yang, Kedar Kirtane, Ritu Chaudhary, Sunil Kumar, Antonio L. Amelio, Anna R. Giuliano, Christine H. Chung
Journal: Cancer Research Communications
Cancer Research Communications (2025)
https://doi.org/10.1158/2767-9764.CRC-25-0180
Published: 11 July 2025
View articletitled, Plasma Cell-Free Human Papillomavirus (HPV) DNA and Oral Gargle HPV DNA in Patients with HPV-related Oropharyngeal Cancer Treated with Radiotherapy
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Includes: Supplementary data
Journal Articles

Modeling high-risk pediatric cancers in zebrafish to inform precision therapy

Open Access
Nadine Azzam, Jamie I. Fletcher, Nicole Melong, Loretta M.S. Lau, M. Emmy M. Dolman, Jie Mao, Gabor Tax, Roxanne Cadiz, Lissandra Tuzi, Alvin Kamili, Biljana Dumevska, Jinhan Xie, Jennifer A. Chan, Donna L. Senger, Stephanie A. Grover, David Malkin, Michelle Haber, Jason N. Berman
Journal: Cancer Research Communications
Cancer Research Communications (2025)
https://doi.org/10.1158/2767-9764.CRC-25-0080
Published: 10 July 2025
View articletitled, Modeling high-risk pediatric cancers in zebrafish to inform precision therapy
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Includes: Supplementary data
Journal Articles

Chemoimmunotherapy outcomes and prognostic factors in patients with advanced, low PD-L1-expressing non-small cell lung cancer

Open Access
Tae Hata, Tadaaki Yamada, Yasuhiro Goto, Akihiko Amano, Yoshiki Negi, Satoshi Watanabe, Naoki Furuya, Tomohiro Oba, Tatsuki Ikoma, Akira Nakao, Keiko Tanimura, Hirokazu Taniguchi, Akihiro Yoshimura, Tomoya Fukui, Daiki Murata, Kyoichi Kaira, Shinsuke Shiotsu, Makoto Hibino, Asuka Okada, Yusuke Chihara, Hayato Kawachi, Takashi Kijima, Koichi Takayama
Journal: Cancer Research Communications
Cancer Research Communications (2025)
https://doi.org/10.1158/2767-9764.CRC-25-0157
Published: 10 July 2025
View articletitled, Chemoimmunotherapy outcomes and prognostic factors in patients with advanced, low PD-L1-expressing non-small cell lung cancer
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Includes: Supplementary data
Journal Articles

Loss of predicted cell adhesion molecule MPZL3 promotes EMT in ovarian cancer

Open Access
Ya-Yun Cheng, Beth L. Worley, Zaineb Javed, Amal T. Elhaw, Priscilla W. Tang, Sarah Al-Saad, Shriya Kamlapurkar, Sierra R. White, Apoorva Uboveja, Karthikeyan Mythreye, Katherine M. Aird, Traci A. Czyzyk, Nadine Hempel
Journal: Cancer Research Communications
Cancer Research Communications (2025)
https://doi.org/10.1158/2767-9764.CRC-24-0591
Published: 09 July 2025
View articletitled, Loss of predicted cell adhesion molecule MPZL3 promotes EMT in ovarian cancer
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Includes: Supplementary data
Journal Articles

Uncovering Novel lncRNAs Linked to Melanoma Growth and Migration with CRISPR Inhibition Screening

Open Access
Stavroula Petroulia, Kathryn Hockemeyer, Shashank Tiwari, Pietro Berico, Sama Shamloo, Seyedeh Elnaz Banijamali, Eleazar Vega-Saenz de Miera, Yixiao Gong, Palaniraja Thandapani, Eric Wang, Jeffrey L. Schloßhauer, Aristotelis Tsirigos, Iman Osman, Ioannis Aifantis, Jochen Imig
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (7): 1102–1118.
https://doi.org/10.1158/2767-9764.CRC-24-0416
Published: 09 July 2025
View articletitled, Uncovering Novel lncRNAs Linked to Melanoma Growth and Migration with CRISPR Inhibition Screening
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Includes: Supplementary data
Journal Articles

Racial Disparities in Analgesic and Psychiatric Medication Use During End-Of-Life Care in Advanced-Stage Colorectal Cancer: A Retrospective Cohort Study

Open Access
John M. Allen, Olga M. Trejos Kweyete, Yi Guo, Jiang Bian, Xiwei Lou, Sherise C. Rogers, Lisa Scarton, David L. DeRemer, Diana J. Wilkie
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (7): 1095–1101.
https://doi.org/10.1158/2767-9764.CRC-25-0164
Published: 08 July 2025
View articletitled, Racial Disparities in Analgesic and Psychiatric Medication Use During End-Of-Life Care in Advanced-Stage Colorectal Cancer: A Retrospective Cohort Study
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Includes: Supplementary data
Journal Articles

Impact of Glucocorticoids on Immune Checkpoint Inhibitor Efficacy and Circulating Biomarkers in Non–Small Cell Lung Cancer Patients

Open Access
Lauren Polyakov, Angelina Lim, Alexandra Meyer, Aubree Mades, Joshua Ni, Ryan Cooper, Shirley Ye, Ryutaro Kajihara, Takaaki Oba, Leslie Contreras, Eihab Abdelfatah, Joy Sarkar, Junko Matsuzaki, Ming Li, Rajeev Sharma, Brahm H. Segal, Robert C. Hsu, Hongbin Chen, Jorge Nieva, Fumito Ito
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (7): 1082–1094.
https://doi.org/10.1158/2767-9764.CRC-25-0051
Published: 07 July 2025
View articletitled, Impact of Glucocorticoids on Immune Checkpoint Inhibitor Efficacy and Circulating Biomarkers in Non–Small Cell Lung Cancer Patients
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Includes: Supplementary data
Journal Articles

Genetic Ancestry, Intrinsic Tumor Subtypes, and Breast Cancer Survival in Latin American Women

Open Access
Daniela Alves da Quinta, Darío Rocha, Cristian Yáñez, Renata Binato, Sheila Coelho Soares-Lima, Xiaosong Huang, Daiana Ganiewich, Valentina A. Zavala, Monica Sans, Alejandra Lopez-Vazquez, Jael Quintero, Olivia Valenzuela, Antonio Quintero-Ramos, Alicia Del Toro-Arreola, Mauricio Cerda, Katherine Marcelain, Susanne Crocamo, Maria Aparecida Nagai, Dirce M. Carraro, Marcia Maria Chiquitelli Marques, Jorge Gómez, Nora Artagaveytia, Adrian Daneri-Navarro, Bettina G. Müller, Javier Retamales, Carlos Velazquez, Elmer A. Fernández, Osvaldo L. Podhajcer, Eliana Abdelhay, Ricardo A. Verdugo, the LACRN Investigators, Andrea S. Llera, Laura Fejerman
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (7): 1070–1081.
https://doi.org/10.1158/2767-9764.CRC-25-0014
Published: 03 July 2025
View articletitled, Genetic Ancestry, Intrinsic Tumor Subtypes, and Breast Cancer Survival in Latin American Women
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Includes: Supplementary data
Journal Articles

The XPO1 inhibitor Eltanexor modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis

Open Access
Andrew E. Evans, Sahida Afroz, Alexa Magstadt, Anup Kasi, Dan A. Dixon
Journal: Cancer Research Communications
Cancer Research Communications (2025)
https://doi.org/10.1158/2767-9764.CRC-25-0052
Published: 02 July 2025
View articletitled, The XPO1 inhibitor Eltanexor modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis
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Includes: Supplementary data
Journal Articles

Protein-Level Analysis of Differential Response to Chemotherapy in Triple-Negative Breast Cancer Identifies CYP1B1 as a Biomarker for Chemotherapy Resistance

Open Access
F. Scott Heinemann, Paul D. Gershon
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (7): 1060–1069.
https://doi.org/10.1158/2767-9764.CRC-25-0034
Published: 01 July 2025
View articletitled, Protein-Level Analysis of Differential Response to Chemotherapy in Triple-Negative Breast Cancer Identifies CYP1B1 as a Biomarker for Chemotherapy Resistance
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Includes: Supplementary data
Journal Articles

Assessing racial disparities in guideline-concordant care and clinical outcomes after surgical resection of non-metastatic colon cancer at a comprehensive cancer center

Open Access
Christina I. Lee, Sharafudeen D. Abubakar, Fan Wu, Hannah Thompson, Farheen Shah, Michele Waters, Jonathan B. Yuval, Hannah Williams, Anisha Luthra, Dana M. Omer, Chin-Tung Chen, Julio Garcia-Aguilar, Francisco Sanchez-Vega
Journal: Cancer Research Communications
Cancer Research Communications (2025)
https://doi.org/10.1158/2767-9764.CRC-24-0633
Published: 30 June 2025
View articletitled, Assessing racial disparities in guideline-concordant care and clinical outcomes after surgical resection of non-metastatic colon cancer at a comprehensive cancer center
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Includes: Supplementary data
Journal Articles

Defining Non–small Cell Lung Cancer Tumor Microenvironment Changes at Primary and Acquired Immune Checkpoint Inhibitor Resistance Using Clinical and Real-World Data

Open Access
Lang Ho Lee, Xin Xu, Thanos Mourikis, Fanying Tang, Lauren Fairchild, Lexiang Ji, Angelo L. Grauel, Joel P. Wagner, Sebastian Szpakowski, Marc R. Pelletier, Lisa Kattenhorn, Laurent Sansregret, Carlotta Costa, Claudia Bossen, Heather Burks, Anna F. Farago, Jincheng Wu
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (6): 1049–1059.
https://doi.org/10.1158/2767-9764.CRC-24-0605
Published: 30 June 2025
View articletitled, Defining Non–small Cell Lung Cancer Tumor Microenvironment Changes at Primary and Acquired Immune Checkpoint Inhibitor Resistance Using Clinical and Real-World Data
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Includes: Supplementary data
Journal Articles

Adiposity status close to diagnosis and its association with prostate cancer survival in the UK biobank

Open Access
Margarita Cariolou, Sofia Christakoudi, Marc J. Gunter, Alicia K. Heath, Amy Berrington de González, Doris SM. Chan, David C. Muller, Konstantinos K. Tsilidis
Journal: Cancer Research Communications
Cancer Research Communications (2025)
https://doi.org/10.1158/2767-9764.CRC-25-0124
Published: 27 June 2025
View articletitled, Adiposity status close to diagnosis and its association with prostate cancer survival in the UK biobank
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Includes: Supplementary data
Journal Articles

Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells

Open Access
Stacia L. Koppenhafer, Elizabeth L. Geary, Mary V. Thomas, Emma E. Croushore, Jessica A.O. Zimmerman, Jenna M. Gedminas, Dawn E. Quelle, Rebecca D. Dodd, David J. Gordon
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (6): 1034–1048.
https://doi.org/10.1158/2767-9764.CRC-25-0058
Published: 27 June 2025
View articletitled, Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells
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Includes: Supplementary data
Journal Articles

High-Throughput Drug Screening of Clear Cell Ovarian Cancer Organoids Reveals Vulnerability to Proteasome Inhibitors and Dinaciclib and Identifies AGR2 as a Therapeutic Target

Open Access
Takuma Yoshimura, Takashi Kamatani, Aki Ookubo, Mio Takahashi, Manabu Itoh, Toshiki Ebisudani, Yohei Masugi, Tomomi Toyonaga, Junko Hamamoto, Keiko Saotome, Kensuke Sakai, Tomoko Yoshihama, Nobuko Moritoki, Shinsuke Shibata, Hiroyuki Yasuda, Toshiro Sato, Taka-Aki Sato, Daisuke Aoki, Wataru Yamagami, Tatsuhiko Tsunoda, Tatsuyuki Chiyoda
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (6): 1018–1033.
https://doi.org/10.1158/2767-9764.CRC-25-0024
Published: 25 June 2025
View articletitled, High-Throughput Drug Screening of Clear Cell Ovarian Cancer Organoids Reveals Vulnerability to Proteasome Inhibitors and Dinaciclib and Identifies AGR2 as a Therapeutic Target
Open the PDF for High-Throughput Drug Screening of Clear Cell Ovarian Cancer Organoids Reveals Vulnerability to Proteasome Inhibitors and Dinaciclib and Identifies AGR2 as a Therapeutic Target in another window
Includes: Supplementary data
Journal Articles

A Phase 1 Safety Study of Evexomostat (SDX-7320) in Patients with Late-Stage Cancer: An Antiangiogenic, Insulin-Sensitizing Drug Conjugate Targeting METAP2

Open Access
Monica M. Mita, Alain C. Mita, Bradley J. Carver, James M. Shanahan, Benjamin A. Mayes, Pierre J. Dufour, David Browning, Alfred Anderson-Villaluz, John S. Petersen, David J. Turnquist, Peter Cornelius
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (6): 1008–1017.
https://doi.org/10.1158/2767-9764.CRC-24-0627
Published: 23 June 2025
View articletitled, A Phase 1 Safety Study of Evexomostat (SDX-7320) in Patients with Late-Stage Cancer: An Antiangiogenic, Insulin-Sensitizing Drug Conjugate Targeting METAP2
Open the PDF for A Phase 1 Safety Study of Evexomostat (SDX-7320) in Patients with Late-Stage Cancer: An Antiangiogenic, Insulin-Sensitizing Drug Conjugate Targeting METAP2 in another window
Includes: Supplementary data
Journal Articles

Cisplatin-Induced APE2 Overexpression Disrupts MYH9 Function and Causes Hearing Loss

Open Access
Qingzhu Wang, Eric E. Irons, Wanying Zhang, Fangfang Zhao, Meng-Han Chang, Esther Dai, Joelle Jeon, Hanna Hong, Rie Maeda, Minseo Kim, Kylin A. Emhoff, Mei Yin, Belinda B. Willard, Qing Y. Zheng, Richard A. Prayson, Jordan Beach, Jennifer S. Yu, Bohua Hu, Jianjun Zhao, Jianhong Lin
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (6): 994–1007.
https://doi.org/10.1158/2767-9764.CRC-24-0506
Published: 20 June 2025
View articletitled, Cisplatin-Induced APE2 Overexpression Disrupts MYH9 Function and Causes Hearing Loss
Open the PDF for Cisplatin-Induced APE2 Overexpression Disrupts MYH9 Function and Causes Hearing Loss in another window
Includes: Supplementary data
Journal Articles

An Acrolein-Based Drug Delivery System Enables Tumor-Specific Sphingosine-1-Phosphate Targeting in Breast Cancer without Lymphocytopenia

Open Access
Masayuki Nagahashi, Miki Komatsu, Sayaka Urano, Mamiko Kuroiwa, Yuria Takahashi, Koji Morimoto, Ambara R. Pradipta, Katsunori Tanaka, Yasuo Miyoshi
Journal: Cancer Research Communications
Cancer Research Communications (2025) 5 (6): 981–993.
https://doi.org/10.1158/2767-9764.CRC-25-0023
Published: 18 June 2025
View articletitled, An Acrolein-Based Drug Delivery System Enables Tumor-Specific Sphingosine-1-Phosphate Targeting in Breast Cancer without Lymphocytopenia
Open the PDF for An Acrolein-Based Drug Delivery System Enables Tumor-Specific Sphingosine-1-Phosphate Targeting in Breast Cancer without Lymphocytopenia in another window
Includes: Supplementary data