1-20 of 167 Search Results for

*

Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Combined Oxygen-enhanced MRI and perfusion imaging detect hypoxia modification from banoxantrone and atovaquone and track their differential mechanisms of action

James PB O'Connor, Victoria Tessyman, Ross A Little, Muhammad Babur, Duncan Forster, Ayse Latif, Susan Cheung, Grazyna Lipowska-Bhalla, Geoff S Higgins, Marie-Claude Asselin, Geoff JM Parker, Kaye J Williams
Journal: Cancer Research Communications
Cancer Research Communications (2024)
https://doi.org/10.1158/2767-9764.CRC-24-0315
Published: 06 September 2024
View article titled, Combined Oxygen-enhanced MRI and perfusion imaging detect hypoxia modification from banoxantrone and atovaquone and track their differential mechanisms of action
Open the PDF for Combined Oxygen-enhanced MRI and perfusion imaging detect hypoxia modification from banoxantrone and atovaquone and track their differential mechanisms of action in another window
Includes: Supplementary data
Journal Articles

MYC is sufficient to generate mid-life high-grade serous ovarian and uterine serous carcinomas in a p53-R270H mouse model

Alexandra Blackman, Amy C Rees, Robert R Bowers, Christian M Jones, Silvia G. Vaena, Madison A Clark, Shelby Carter, Evan D Villamor, Della Evans, Anthony J Emanuel, George Fullbright, Matthew S O'Malley, Richard L. Carpenter, David T Long, Laura S Spruill, Martin J Romeo, Brian C Orr, Kristi L Helke, Joe R Delaney
Journal: Cancer Research Communications
Cancer Research Communications (2024)
https://doi.org/10.1158/2767-9764.CRC-24-0144
Published: 03 September 2024
View article titled, MYC is sufficient to generate mid-life high-grade serous ovarian and uterine serous carcinomas in a p53-R270H mouse model
Open the PDF for MYC is sufficient to generate mid-life high-grade serous ovarian and uterine serous carcinomas in a p53-R270H mouse model in another window
Includes: Supplementary data
Journal Articles

NCI's Proteomic Data Commons: A Cloud-Based Proteomics Repository Empowering Comprehensive Cancer Analysis Through Cross-Referencing with Genomic and Imaging Data

Ratna R Thangudu, Michael Holck, Deepak Singhal, Alexander Pilozzi, Nathan Edwards, Paul A Rudnick, Marcin J Domagalski, Padmini Chilappagari, Lei Ma, Yi Xin, Toan Le, Kristen Nyce, Rekha Chaudhary, Karen A Ketchum, Aaron Maurais, Brian Connolly, Michael Riffle, Matthew C. Chambers, Brendan MacLean, Michael J MacCoss, Peter B McGarvey, Anand Basu, John Otridge, Esmeralda Casas-Silva, Sudha Venkatachari, Henry Rodriguez, Xu Zhang
Journal: Cancer Research Communications
Cancer Research Communications (2024)
https://doi.org/10.1158/2767-9764.CRC-24-0243
Published: 03 September 2024
View article titled, NCI's Proteomic Data Commons: A Cloud-Based Proteomics Repository Empowering Comprehensive Cancer Analysis Through Cross-Referencing with Genomic and Imaging Data
Open the PDF for NCI's Proteomic Data Commons: A Cloud-Based Proteomics Repository Empowering Comprehensive Cancer Analysis Through Cross-Referencing with Genomic and Imaging Data in another window
Journal Articles

A drug discovery pipeline for MAPK/ERK pathway inhibitors in C. elegans

Szymon Gorgoń, Ola Billing, Anna Ulrika Eriksson, Oskar Hemmingsson
Journal: Cancer Research Communications
Cancer Research Communications (2024)
https://doi.org/10.1158/2767-9764.CRC-24-0221
Published: 30 August 2024
View article titled, A drug discovery pipeline for MAPK/ERK pathway inhibitors in C. elegans
Open the PDF for A drug discovery pipeline for MAPK/ERK pathway inhibitors in C. elegans in another window
Includes: Supplementary data
Journal Articles

Systematic Evaluation of Tyrosine Kinase Inhibitors as OATP1B1 Substrates Using a Competitive Counterflow Screen

Thomas Drabison, Mike Boeckman, Yan Yang, Kevin M Huang, Peter de Bruijn, Mahesh R Nepal, Josie A Silvaroli, Anika T Chowdhury, Eric D Eisenmann, Xiaolin Cheng, Navjotsingh Pabla, Ron H.J. Mathijssen, Sharyn D. Baker, Shuiying Hu, Alex Sparreboom, Zahra Talebi
Journal: Cancer Research Communications
Cancer Research Communications (2024)
https://doi.org/10.1158/2767-9764.CRC-24-0332
Published: 29 August 2024
View article titled, Systematic Evaluation of Tyrosine Kinase Inhibitors as OATP1B1 Substrates Using a Competitive Counterflow Screen
Open the PDF for Systematic Evaluation of Tyrosine Kinase Inhibitors as OATP1B1 Substrates Using a Competitive Counterflow Screen in another window
Includes: Supplementary data
Journal Articles

Engineering oncogenic hotspot mutations on SF3B1 via CRISPR-directed PRECIS mutagenesis

Mike Fernandez, Lei Yu, Qiong Jia, Xuesong Wang, Kevyn L Hart, Zhenyu Jia, Ren-Jang Lin, Lili Wang
Journal: Cancer Research Communications
Cancer Research Communications (2024)
https://doi.org/10.1158/2767-9764.CRC-24-0145
Published: 28 August 2024
View article titled, Engineering oncogenic hotspot mutations on SF3B1 via CRISPR-directed PRECIS mutagenesis
Open the PDF for Engineering oncogenic hotspot mutations on SF3B1 via CRISPR-directed PRECIS mutagenesis in another window
Includes: Supplementary data
Journal Articles

Long-lasting response to lorlatinib in patients with ALK-driven relapsed or refractory neuroblastoma monitored with circulating tumor DNA analysis

Torben Ek, Raghda R Ibrahim, Hartmut Vogt, Kleopatra Georgantzi, Catarina Träger, Jennie Gaarder, Anna Djos, Ida Rahmqvist, Elisabeth Mellström, Fani Pujol-Calderón, Christoffer Vannas, Lina Hansson, Henrik Fagman, Diana Treis, Susanne Fransson, Tobias Österlund, Tzu-Po Chuang, Bronte Manouk Verhoeven, Anders Ståhlberg, Ruth H Palmer, Bengt Hallberg, Tommy Martinsson, Per Kogner, Martin Dalin
Journal: Cancer Research Communications
Cancer Research Communications (2024)
https://doi.org/10.1158/2767-9764.CRC-24-0338
Published: 23 August 2024
View article titled, Long-lasting response to lorlatinib in patients with ALK-driven relapsed or refractory neuroblastoma monitored with circulating tumor DNA analysis
Open the PDF for Long-lasting response to lorlatinib in patients with ALK-driven relapsed or refractory neuroblastoma monitored with circulating tumor DNA analysis in another window
Includes: Supplementary data
Journal Articles

The Proteogenomics of Prostate Cancer Radioresistance

Roni Haas, Gavin Frame, Shahbaz Khan, Beth K Neilsen, Boon Hao Hong, Celestia P.X. Yeo, Takafumi N Yamaguchi, Enya H.W. Ong, Wenyan Zhao, Benjamin Carlin, Eugenia L.L. Yeo, Kah M. Tan, Yuan Zhe Bugh, Chenghao Zhu, Rupert Hugh-White, Julie Livingstone, Dennis J.J. Poon, Pek L. Chu, Yash Patel, Shu Tao, Vladimir Ignatchenko, Natalie J Kurganovs, Geoff S. Higgins, Michelle R Downes, Andrew Loblaw, Danny Vesprini, Amar U Kishan, Melvin L.K. Chua, Thomas Kislinger, Paul C Boutros, Stanley K Liu
Journal: Cancer Research Communications
Cancer Research Communications (2024)
https://doi.org/10.1158/2767-9764.CRC-24-0292
Published: 21 August 2024
View article titled, The Proteogenomics of Prostate Cancer Radioresistance
Open the PDF for The Proteogenomics of Prostate Cancer Radioresistance in another window
Includes: Supplementary data
Journal Articles

A Database Tool Integrating Genomic and Pharmacologic Data from Adrenocortical Carcinoma (ACC) Cell Lines, PDX, and Patient Samples

Yashuhiro Arakawa, Fathi Elloumi, Sudhir Varma, Prashant Khandagale, Ukhyun Jo, Suresh Kumar, Nitin Roper, William C. Reinhold, Robert W. Robey, Naoko Takebe, Michael M Gottesman, Craig J. Thomas, Valentina Boeva, Alfredo Berruti, Andrea Abate, Mariangela Tamburello, Sandra Sigala, Constanze Hantel, Isabel Weigand, Margaret E Wierman, Katja Kiseljak-Vassiliades, Jaydira Del Rivero, Yves Pommier
Journal: Cancer Research Communications
Cancer Research Communications (2024)
https://doi.org/10.1158/2767-9764.CRC-24-0100
Published: 20 August 2024
View article titled, A Database Tool Integrating Genomic and Pharmacologic Data from Adrenocortical Carcinoma (ACC) Cell Lines, PDX, and Patient Samples
Open the PDF for A Database Tool Integrating Genomic and Pharmacologic Data from Adrenocortical Carcinoma (ACC) Cell Lines, PDX, and Patient Samples in another window
Includes: Supplementary data
Journal Articles

Transcriptome Deconvolution Reveals Absence of Cancer Cell Expression Signature in Immune Checkpoint Blockade Response

Yu Amanda Guo, Tanmay Kulshrestha, Mei Mei Chang, Irfahan Kassam, Egor Revkov, Simone Rizzetto, Aaron C. Tan, Daniel S.W. Tan, Iain Beehuat Tan, Anders J. Skanderup
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (6): 1581–1596.
https://doi.org/10.1158/2767-9764.CRC-23-0442
Published: 26 June 2024
View article titled, Transcriptome Deconvolution Reveals Absence of Cancer Cell Expression Signature in Immune Checkpoint Blockade Response
Open the PDF for Transcriptome Deconvolution Reveals Absence of Cancer Cell Expression Signature in Immune Checkpoint Blockade Response in another window
Includes: Supplementary data
Journal Articles

HDAC6 Inhibition Releases HR23B to Activate Proteasomes, Expand the Tumor Immunopeptidome and Amplify T-cell Antimyeloma Activity

Priyanka S. Rana, James J. Ignatz-Hoover, Byung-Gyu Kim, Ehsan Malek, Yuriy Federov, Drew Adams, Timothy Chan, James J. Driscoll
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (6): 1517–1532.
https://doi.org/10.1158/2767-9764.CRC-23-0528
Published: 18 June 2024
View article titled, HDAC6 Inhibition Releases HR23B to Activate Proteasomes, Expand the Tumor Immunopeptidome and Amplify T-cell Antimyeloma Activity
Open the PDF for HDAC6 Inhibition Releases HR23B to Activate Proteasomes, Expand the Tumor Immunopeptidome and Amplify T-cell Antimyeloma Activity in another window
Includes: Supplementary data
Journal Articles

Mechanistic Characterization of Cancer-associated Fibroblast Depletion via an Antibody–Drug Conjugate Targeting Fibroblast Activation Protein

Joseph P. Gallant, Hallie M. Hintz, Gihan S. Gunaratne, Matthew T. Breneman, Emma E. Recchia, Jayden L. West, Kendahl L. Ott, Erika Heninger, Abigail E. Jackson, Natalie Y. Luo, Zachary T. Rosenkrans, Reinier Hernandez, Shuang G. Zhao, Joshua M. Lang, Labros Meimetis, David Kosoff, Aaron M. LeBeau
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (6): 1481–1494.
https://doi.org/10.1158/2767-9764.CRC-24-0248
Published: 12 June 2024
View article titled, Mechanistic Characterization of Cancer-associated Fibroblast Depletion via an Antibody–Drug Conjugate Targeting Fibroblast Activation Protein
Open the PDF for Mechanistic Characterization of Cancer-associated Fibroblast Depletion via an Antibody–Drug Conjugate Targeting Fibroblast Activation Protein in another window
Includes: Supplementary data
Journal Articles

Multi-omics Analysis of a Fecal Microbiota Transplantation Trial Identifies Novel Aspects of Acute GVHD Pathogenesis

Armin Rashidi, Maryam Ebadi, Tauseef U. Rehman, Heba Elhusseini, David Kazadi, Hossam Halaweish, Mohammad H. Khan, Andrea Hoeschen, Qing Cao, Xianghua Luo, Amanda J. Kabage, Sharon Lopez, Sivapriya Ramamoorthy, Shernan G. Holtan, Daniel J. Weisdorf, Alexander Khoruts, Christopher Staley
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (6): 1454–1466.
https://doi.org/10.1158/2767-9764.CRC-24-0138
Published: 10 June 2024
View article titled, Multi-omics Analysis of a Fecal Microbiota Transplantation Trial Identifies Novel Aspects of Acute GVHD Pathogenesis
Open the PDF for Multi-omics Analysis of a Fecal Microbiota Transplantation Trial Identifies Novel Aspects of Acute GVHD Pathogenesis in another window
Includes: Supplementary data
Journal Articles

Evaluation of Copanlisib in Combination with Eribulin in Triple-negative Breast Cancer Patient-derived Xenograft Models

Zhanfang Guo, Jingqin Luo, R. Jay Mashl, Jeremy Hoog, Piyush Maiti, Nikki Fettig, Sherri R. Davies, Rebecca Aft, Jason M. Held, Ramaswamy Govindan, Li Ding, Shunqiang Li, Cornelius von Morze, Gerburg M. Wulf, Kooresh I. Shoghi, Cynthia X. Ma
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (6): 1430–1440.
https://doi.org/10.1158/2767-9764.CRC-24-0047
Published: 05 June 2024
View article titled, Evaluation of Copanlisib in Combination with Eribulin in Triple-negative Breast Cancer Patient-derived Xenograft Models
Open the PDF for Evaluation of Copanlisib in Combination with Eribulin in Triple-negative Breast Cancer Patient-derived Xenograft Models in another window
Includes: Supplementary data
Journal Articles

Molecular Landscape and Clinical Implication of CCNE1-amplified Esophagogastric Cancer

Naryan Rustgi, Sharon Wu, Timothy Samec, Phillip Walker, Joanne Xiu, Emil Lou, Sanjay Goel, Anwaar Saeed, Ryan H. Moy
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (6): 1399–1409.
https://doi.org/10.1158/2767-9764.CRC-23-0496
Published: 03 June 2024
View article titled, Molecular Landscape and Clinical Implication of <em>CCNE1-</em>amplified Esophagogastric Cancer
Open the PDF for Molecular Landscape and Clinical Implication of <em>CCNE1-</em>amplified Esophagogastric Cancer in another window
Includes: Supplementary data
Journal Articles

Pan-Cancer Interrogation of B7-H3 (CD276) as an Actionable Therapeutic Target Across Human Malignancies

Carly D. Miller, John R. Lozada, Nicholas A. Zorko, Andrew Elliott, Allison Makovec, Milan Radovich, Elisabeth I. Heath, Neeraj Agarwal, Rana R. Mckay, Rohan Garje, Bruno R. Bastos, Dave S.B. Hoon, Jacob J. Orme, Oliver Sartor, Ari VanderWalde, Chadi Nabhan, George Sledge, Eugene Shenderov, Scott M. Dehm, Emil Lou, Jeffrey S. Miller, Justin H. Hwang, Emmanuel S. Antonarakis
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (5): 1369–1379.
https://doi.org/10.1158/2767-9764.CRC-23-0546
Published: 30 May 2024
View article titled, Pan-Cancer Interrogation of B7-H3 (<em>CD276</em>) as an Actionable Therapeutic Target Across Human Malignancies
Open the PDF for Pan-Cancer Interrogation of B7-H3 (<em>CD276</em>) as an Actionable Therapeutic Target Across Human Malignancies in another window
Includes: Supplementary data
Journal Articles

Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects

Alexandria P. Eiken, Audrey L. Smith, Sydney A. Skupa, Elizabeth Schmitz, Sandeep Rana, Sarbjit Singh, Siddhartha Kumar, Jayapal Reddy Mallareddy, Aguirre A de Cubas, Akshay Krishna, Achyuth Kalluchi, M. Jordan Rowley, Christopher R. D'Angelo, Matthew A. Lunning, R. Gregory Bociek, Julie M. Vose, Amarnath Natarajan, Dalia El-Gamal
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (5): 1328–1343.
https://doi.org/10.1158/2767-9764.CRC-24-0071
Published: 22 May 2024
View article titled, Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects
Open the PDF for Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects in another window
Includes: Supplementary data
Journal Articles

The FKBP51s Splice Isoform Predicts Unfavorable Prognosis in Patients with Glioblastoma

Carolina Giordano, Laura Marrone, Simona Romano, Giuseppe Maria Della Pepa, Carlo Maria Donzelli, Martina Tufano, Mario Capasso, Vito Alessandro Lasorsa, Cristina Quintavalle, Giulia Guerri, Matia Martucci, Annamaria Auricchio, Marco Gessi, Evis Sala, Alessandro Olivi, Maria Fiammetta Romano, Simona Gaudino
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (5): 1296–1306.
https://doi.org/10.1158/2767-9764.CRC-24-0083
Published: 16 May 2024
View article titled, The FKBP51s Splice Isoform Predicts Unfavorable Prognosis in Patients with Glioblastoma
Open the PDF for The FKBP51s Splice Isoform Predicts Unfavorable Prognosis in Patients with Glioblastoma in another window
Includes: Supplementary data
Journal Articles

Exercise-induced β2-adrenergic Receptor Activation Enhances the Antileukemic Activity of Expanded γδ T-Cells via DNAM-1 Upregulation and PVR/Nectin-2 Recognition

Forrest L. Baker, Kyle A. Smith, Preetesh L. Mylabathula, Tiffany M. Zúñiga, Douglass M. Diak, Helena Batatinha, Grace M. Niemiro, Michael D. Seckeler, Charles R. Pedlar, Daniel P. O'Connor, Jamie Colombo, Emmanuel Katsanis, Richard J. Simpson
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (5): 1253–1267.
https://doi.org/10.1158/2767-9764.CRC-23-0570
Published: 13 May 2024
View article titled, Exercise-induced β2-adrenergic Receptor Activation Enhances the Antileukemic Activity of Expanded γδ T-Cells via DNAM-1 Upregulation and PVR/Nectin-2 Recognition
Open the PDF for Exercise-induced β2-adrenergic Receptor Activation Enhances the Antileukemic Activity of Expanded γδ T-Cells via DNAM-1 Upregulation and PVR/Nectin-2 Recognition in another window
Includes: Supplementary data
Journal Articles

Urolithin-A Promotes CD8+ T Cell–mediated Cancer Immunosurveillance via FOXO1 Activation

Pierpaolo Ginefra, Helen Carrasco Hope, Yi-Hsuan Chiang, Sophie Nutten, Stephanie Blum, George Coukos, Nicola Vannini
Journal: Cancer Research Communications
Cancer Research Communications (2024) 4 (5): 1189–1198.
https://doi.org/10.1158/2767-9764.CRC-24-0022
Published: 03 May 2024
View article titled, Urolithin-A Promotes CD8<sup>+</sup> T Cell–mediated Cancer Immunosurveillance via FOXO1 Activation
Open the PDF for Urolithin-A Promotes CD8<sup>+</sup> T Cell–mediated Cancer Immunosurveillance via FOXO1 Activation in another window
Includes: Supplementary data