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Journal Articles

Peritumoral immune suppressive mechanisms impede intratumoral lymphocyte infiltration into CRC liver versus lung metastases

Jian Ye, Weihua Guo, Chongkai Wang, Colt A Egelston, Massimo D'Apuzzo, Geereesh Shankar, Marwan G Fakih, Peter P Lee
Journal: Cancer Research Communications
Cancer Research Communications (2023)
https://doi.org/10.1158/2767-9764.CRC-23-0212
Published: 27 September 2023
View article titled, Peritumoral immune suppressive mechanisms impede intratumoral lymphocyte infiltration into CRC liver versus lung metastases
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Includes: Supplementary data
Journal Articles

Fusobacterium nucleatum Load Correlates with KRAS Mutation and Sessile Serrated Pathogenesis in Colorectal Adenocarcinoma

Koki Takeda, Minoru Koi, Yoshiki Okita, Sija Sajibu, Temitope O. Keku, John M. Carethers
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (9): 1940–1951.
https://doi.org/10.1158/2767-9764.CRC-23-0179
Published: 26 September 2023
View article titled, <em>Fusobacterium nucleatum</em> Load Correlates with <em>KRAS</em> Mutation and Sessile Serrated Pathogenesis in Colorectal Adenocarcinoma
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Includes: Supplementary data
Journal Articles

HER2-Selective and Reversible Tyrosine Kinase Inhibitor Tucatinib Potentiates the Activity of T-DM1 in Preclinical Models of HER2-positive Breast Cancer

Devra Olson, Janelle Taylor, Kelsi Willis, Kelly Hensley, Sean Allred, Margo Zaval, Lauren Farr, Robert Thurman, Nishi Jain, Renee Hein, Michelle Ulrich, Scott Peterson, Anita Kulukian
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (9): 1927–1939.
https://doi.org/10.1158/2767-9764.CRC-23-0302
Published: 25 September 2023
View article titled, HER2-Selective and Reversible Tyrosine Kinase Inhibitor Tucatinib Potentiates the Activity of T-DM1 in Preclinical Models of HER2-positive Breast Cancer
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Includes: Supplementary data
Journal Articles

Metastatic competency and tumor spheroid formation are independent cell states governed by RB in lung adenocarcinoma

Nelson F. Freeburg, Nia Peterson, Dain A. Ruiz, Amy C Gladstein, David M. Feldser
Journal: Cancer Research Communications
Cancer Research Communications (2023)
https://doi.org/10.1158/2767-9764.CRC-23-0172
Published: 20 September 2023
View article titled, Metastatic competency and tumor spheroid formation are independent cell states governed by RB in lung adenocarcinoma
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Includes: Supplementary data
Journal Articles

Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment

Jesus Amo-Aparicio, Adrian Dominguez, Shaikh M. Atif, Alberto Dinarello, Tania Azam, Kibrom M. Alula, Miles Piper, Christopher H. Lieu, Robert W. Lentz, Alexis D. Leal, Stacey M. Bagby, Wells A. Messersmith, Sana D. Karam, Charles A. Dinarello, Todd M. Pitts, Carlo Marchetti
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (9): 1899–1911.
https://doi.org/10.1158/2767-9764.CRC-23-0065
Published: 20 September 2023
View article titled, Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment
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Includes: Supplementary data
Journal Articles

AKR1C3 Converts Castrate and Post-Abiraterone DHEA-S into Testosterone to Stimulate Growth of Prostate Cancer Cells via 5-Androstene-3β,17β-Diol

Andrea J. Detlefsen, Clementina A. Mesaros, Ling Duan, Trevor M. Penning
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (9): 1888–1898.
https://doi.org/10.1158/2767-9764.CRC-23-0235
Published: 19 September 2023
View article titled, AKR1C3 Converts Castrate and Post-Abiraterone DHEA-S into Testosterone to Stimulate Growth of Prostate Cancer Cells via 5-Androstene-3β,17β-Diol
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Includes: Supplementary data
Journal Articles

A Druggable FOXA1-Glucocorticoid Receptor Transcriptional Axis Drives Tumor Growth in a Subset of Non-Small Cell Lung Cancer

M. Dorso, Payal T. Patel, Aleksandr Pankov, Jacob A. Boyer, Rajesh K. Soni, Isabella S. Del Priore, Omar Hayatt, Amanda Kulick, Connor J. Hagen, Elisa de Stanchina, Melissa R. Junttila, Anneleen Daemen, Lori S. Friedman, Ronald C. Hendrickson, Sarat Chandarlapaty
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (9): 1788–1799.
https://doi.org/10.1158/2767-9764.CRC-23-0310
Published: 07 September 2023
View article titled, A Druggable FOXA1-Glucocorticoid Receptor Transcriptional Axis Drives Tumor Growth in a Subset of Non-Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Single-cell Profiling Uncovers a Muc4-Expressing Metaplastic Gastric Cell Type Sustained by Helicobacter pylori-driven Inflammation

Valerie P. O'Brien, Yuqi Kang, Meera K. Shenoy, Greg Finak, William C. Young, Julien Dubrulle, Lisa Koch, Armando E. Rodriguez Martinez, Jeffery Williams, Elizabeth Donato, Surinder K. Batra, Cecilia C.S. Yeung, William M. Grady, Meghan A. Koch, Raphael Gottardo, Nina R. Salama
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (9): 1756–1769.
https://doi.org/10.1158/2767-9764.CRC-23-0142
Published: 05 September 2023
View article titled, Single-cell Profiling Uncovers a <em>Muc4</em>-Expressing Metaplastic Gastric Cell Type Sustained by <em>Helicobacter pylori</em>-driven Inflammation
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Includes: Supplementary data
Journal Articles

Natural Killer Cell Activation by Ubiquitin-specific Protease 6 Mediates Tumor Suppression in Ewing Sarcoma

Kanika Jain, Ian C. Henrich, Laura Quick, Robert Young, Shreya Mondal, Andre M. Oliveira, Gerd A. Blobel, Margaret M. Chou
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (8): 1615–1627.
https://doi.org/10.1158/2767-9764.CRC-22-0505
Published: 22 August 2023
View article titled, Natural Killer Cell Activation by Ubiquitin-specific Protease 6 Mediates Tumor Suppression in Ewing Sarcoma
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Includes: Multimedia, Supplementary data
Journal Articles

Targeted Single-cell Isolation of Spontaneously Escaping Live Melanoma Cells for Comparative Transcriptomics

Jacqueline L.E. Tearle, Satya N.V. Arjunan, Szun S. Tay, Feyza Colakoglu, James Cremasco, Matteo Golo, Maté Biro
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (8): 1524–1537.
https://doi.org/10.1158/2767-9764.CRC-22-0305
Published: 11 August 2023
View article titled, Targeted Single-cell Isolation of Spontaneously Escaping Live Melanoma Cells for Comparative Transcriptomics
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Includes: Multimedia, Supplementary data
Journal Articles

Phase II Window Study of Olaparib Alone or with Cisplatin or Durvalumab in Operable Head and Neck Cancer

Myrto Moutafi, Georgia-Angeliki Koliou, George Papaxoinis, Panagiota Economopoulou, Ioannis Kotsantis, Maria Gkotzamanidou, Maria Anastasiou, Dimitrios Pectasides, Efthymios Kyrodimos, Alexander Delides, Evangelos Giotakis, Nikolaos G. Papadimitriou, Ioannis G. Panayiotides, Christos Perisanidis, Aileen I. Fernandez, Vasiliki Xirou, Christos Poulios, Eleni Gagari, Vesal Yaghoobi, Niki Gavrielatou, Saba Shafi, Thazin Nwe Aung, Andromachi Kougioumtzopoulou, Vassilis Kouloulias, Konstantinos Palialexis, Stavros Gkolfinopoulos, Areti Strati, Evi Lianidou, George Fountzilas, David L. Rimm, Periklis G. Foukas, Amanda Psyrri
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (8): 1514–1523.
https://doi.org/10.1158/2767-9764.CRC-23-0051
Published: 10 August 2023
View article titled, Phase II Window Study of Olaparib Alone or with Cisplatin or Durvalumab in Operable Head and Neck Cancer
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Includes: Supplementary data
Journal Articles

MHC Class II is Induced by IFNγ and Follows Three Distinct Patterns of Expression in Colorectal Cancer Organoids

Oliver J. Pickles, Kasun Wanigasooriya, Anetta Ptasinska, Akshay J. Patel, Helen L. Robbins, Claire Bryer, Celina M. Whalley, Louise Tee, Neeraj Lal, Claudia M.A. Pinna, Nahla Elzefzafy, Philippe Taniere, Andrew D. Beggs, Gary M. Middleton
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (8): 1501–1513.
https://doi.org/10.1158/2767-9764.CRC-23-0091
Published: 09 August 2023
View article titled, MHC Class II is Induced by IFNγ and Follows Three Distinct Patterns of Expression in Colorectal Cancer Organoids
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Includes: Supplementary data
Journal Articles

Dual Blockade of EP2 and EP4 Signaling is Required for Optimal Immune Activation and Antitumor Activity Against Prostaglandin-Expressing Tumors

Brian J. Francica, Anja Holtz, Justine Lopez, David Freund, Austin Chen, Dingzhi Wang, David Powell, Franciele Kipper, Dipak Panigrahy, Raymond N. Dubois, Chan C. Whiting, Peppi Prasit, Thomas W. Dubensky
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (8): 1486–1500.
https://doi.org/10.1158/2767-9764.CRC-23-0249
Published: 08 August 2023
View article titled, Dual Blockade of EP2 and EP4 Signaling is Required for Optimal Immune Activation and Antitumor Activity Against Prostaglandin-Expressing Tumors
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Includes: Supplementary data
Journal Articles

Exploring the Onset and Progression of Prostate Cancer through a Multicellular Agent-based Model

Margot Passier, Maisa N.G. van Genderen, Anniek Zaalberg, Jeroen Kneppers, Elise M. Bekers, Andries M. Bergman, Wilbert Zwart, Federica Eduati
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (8): 1473–1485.
https://doi.org/10.1158/2767-9764.CRC-23-0097
Published: 07 August 2023
View article titled, Exploring the Onset and Progression of Prostate Cancer through a Multicellular Agent-based Model
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Includes: Multimedia, Supplementary data
Journal Articles

Synergism Between IL21 and Anti-PD-1 Combination Therapy is Underpinned by the Coordinated Reprogramming of the Immune Cellular Network in the Tumor Microenvironment

Shaoxian Wu, Hao Huang, Runzi Sun, David Shihong Gao, Fan Ye, Jianing Huang, Ella Li, Andrew Ni, Kevin GuoKai Lu, Kong Chen, Jingting Jiang, Penelope A. Morel, Ziyang Zhong, Binfeng Lu
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (8): 1460–1472.
https://doi.org/10.1158/2767-9764.CRC-23-0012
Published: 04 August 2023
View article titled, Synergism Between IL21 and Anti-PD-1 Combination Therapy is Underpinned by the Coordinated Reprogramming of the Immune Cellular Network in the Tumor Microenvironment
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Includes: Supplementary data
Journal Articles

The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer

Lucie Van Emmenis, Sheng-Yu Ku, Kaitlyn Gayvert, Jonathan R. Branch, Nicholas J. Brady, Subhasree Basu, Michael Russell, Joanna Cyrta, Aram Vosoughi, Verena Sailer, Hussein Alnajar, Etienne Dardenne, Elena Koumis, Loredana Puca, Brian D. Robinson, Michael D. Feldkamp, Annmarie Winkis, Nathan Majewski, Brent Rupnow, Marco M. Gottardis, Olivier Elemento, Mark A. Rubin, Himisha Beltran, David S. Rickman
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (8): 1447–1459.
https://doi.org/10.1158/2767-9764.CRC-22-0491
Published: 03 August 2023
View article titled, The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer
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Includes: Supplementary data
Journal Articles

Immunologic Assessment of Tumors from a Race-matched Military Cohort Identifies Mast Cell Depletion as a Marker of Prostate Cancer Progression

Cara C. Schafer, Jiji Jiang, Sally Elsamanoudi, Darryl Nousome, Denise Y. Young, Yingjie Song, Isabell A. Sesterhenn, Gregory T. Chesnut, Shyh-Han Tan
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (8): 1423–1434.
https://doi.org/10.1158/2767-9764.CRC-22-0463
Published: 01 August 2023
View article titled, Immunologic Assessment of Tumors from a Race-matched Military Cohort Identifies Mast Cell Depletion as a Marker of Prostate Cancer Progression
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Includes: Supplementary data
Journal Articles

Characterizing the Immune Microenvironment and Neoantigen Landscape of Hürthle Cell Carcinoma to Identify Potential Immunologic Vulnerabilities

Ian Ganly, Fengshen Kuo, Vladimir Makarov, Yiyu Dong, Ronald Ghossein, Bin Xu, Luc G.T. Morris, Timothy A. Chan
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (7): 1409–1422.
https://doi.org/10.1158/2767-9764.CRC-23-0120
Published: 31 July 2023
View article titled, Characterizing the Immune Microenvironment and Neoantigen Landscape of Hürthle Cell Carcinoma to Identify Potential Immunologic Vulnerabilities
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Includes: Supplementary data
Journal Articles

Identification of an Imidazopyridine-based Compound as an Oral Selective Estrogen Receptor Degrader for Breast Cancer Therapy

Mengwu Pan, Valeria Solozobova, Nane C. Kuznik, Nicole Jung, Simone Gräßle, Victor Gourain, Yvonne M. Heneka, Christina A. Cramer von Clausbruch, Olaf Fuhr, Ravi S. N. Munuganti, Danilo Maddalo, Christine Blattner, Antje Neeb, Adam Sharp, Laura Cato, Carsten Weiss, Rinath M. Jeselsohn, Veronique Orian-Rousseau, Stefan Bräse, Andrew C. B. Cato
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (7): 1378–1396.
https://doi.org/10.1158/2767-9764.CRC-23-0111
Published: 27 July 2023
View article titled, Identification of an Imidazopyridine-based Compound as an Oral Selective Estrogen Receptor Degrader for Breast Cancer Therapy
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Includes: Supplementary data
Journal Articles

Integrated Multi-omics Analysis of Early Lung Adenocarcinoma Links Tumor Biological Features with Predicted Indolence or Aggressiveness

Maria-Fernanda Senosain, Yong Zou, Khushbu Patel, Shilin Zhao, Alexis Coullomb, Dianna J. Rowe, Jonathan M. Lehman, Jonathan M. Irish, Fabien Maldonado, Michael N. Kammer, Vera Pancaldi, Carlos F. Lopez
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (7): 1350–1365.
https://doi.org/10.1158/2767-9764.CRC-22-0373
Published: 26 July 2023
View article titled, Integrated Multi-omics Analysis of Early Lung Adenocarcinoma Links Tumor Biological Features with Predicted Indolence or Aggressiveness
Open the PDF for Integrated Multi-omics Analysis of Early Lung Adenocarcinoma Links Tumor Biological Features with Predicted Indolence or Aggressiveness in another window
Includes: Supplementary data