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Journal Articles

An Early Neoplasia Index (ENI10), Based on Molecular Identity of CD10 Cells and Associated Stemness Biomarkers, is a Predictor of Patient Outcome in Many Cancers

Boris Guyot, Flora Clément, Youenn Drouet, Xenia Schmidt, Sylvain Lefort, Emmanuel Delay, Isabelle Treilleux, Jean-Philippe Foy, Sandrine Jeanpierre, Emilie Thomas, Janice Kielbassa, Laurie Tonon, Helen He Zhu, Pierre Saintigny, Wei-Qiang Gao, Arnaud de la Fouchardiere, Franck Tirode, Alain Viari, Jean-Yves Blay, Véronique Maguer-Satta
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (9): 1966–1980.
https://doi.org/10.1158/2767-9764.CRC-23-0196
Published: 29 September 2023
View article titled, An Early Neoplasia Index (ENI10), Based on Molecular Identity of CD10 Cells and Associated Stemness Biomarkers, is a Predictor of Patient Outcome in Many Cancers
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Includes: Supplementary data
Journal Articles

DNA2 nuclease inhibition confers synthetic lethality in cancers with mutant p53 and synergizes with PARP inhibitors

Helena Folly-Kossi, Joshua D Graves, Lidija A. Wilhelms Garan, Fang-Tsyr Lin, Weei-Chin Lin
Journal: Cancer Research Communications
Cancer Research Communications (2023)
https://doi.org/10.1158/2767-9764.CRC-23-0166
Published: 27 September 2023
View article titled, DNA2 nuclease inhibition confers synthetic lethality in cancers with mutant p53 and synergizes with PARP inhibitors
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Includes: Supplementary data
Journal Articles

Fusobacterium nucleatum Load Correlates with KRAS Mutation and Sessile Serrated Pathogenesis in Colorectal Adenocarcinoma

Koki Takeda, Minoru Koi, Yoshiki Okita, Sija Sajibu, Temitope O. Keku, John M. Carethers
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (9): 1940–1951.
https://doi.org/10.1158/2767-9764.CRC-23-0179
Published: 26 September 2023
View article titled, <em>Fusobacterium nucleatum</em> Load Correlates with <em>KRAS</em> Mutation and Sessile Serrated Pathogenesis in Colorectal Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.

Kay Nakazawa, Taryn Shaw, Young K Song, Marilyn Kouassi-Brou, Anna Molotkova, Purushottam B Tiwari, Hsien-Chao Chou, Xinyu Wen, Jun S. Wei, Emre Deniz, Jeffrey Toretsky, Charles Keller, Frederic G. Barr, Javed Khan, Aykut Üren
Journal: Cancer Research Communications
Cancer Research Communications (2023)
https://doi.org/10.1158/2767-9764.CRC-23-0119
Published: 21 September 2023
View article titled, Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.
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Includes: Supplementary data
Journal Articles

Chromatin accessibility landscape of human triple-negative breast cancer cell lines reveals variation by patient donor ancestry

Alexandra R Harris, Gatikrushna Panigrahi, Huaitian Liu, Vishal N Koparde, Maeve Bailey-Whyte, Tiffany H Dorsey, Clayton C. Yates, Stefan Ambs
Journal: Cancer Research Communications
Cancer Research Communications (2023)
https://doi.org/10.1158/2767-9764.CRC-23-0236
Published: 21 September 2023
View article titled, Chromatin accessibility landscape of human triple-negative breast cancer cell lines reveals variation by patient donor ancestry
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Includes: Supplementary data
Journal Articles

Metastatic competency and tumor spheroid formation are independent cell states governed by RB in lung adenocarcinoma

Nelson F. Freeburg, Nia Peterson, Dain A. Ruiz, Amy C Gladstein, David M. Feldser
Journal: Cancer Research Communications
Cancer Research Communications (2023)
https://doi.org/10.1158/2767-9764.CRC-23-0172
Published: 20 September 2023
View article titled, Metastatic competency and tumor spheroid formation are independent cell states governed by RB in lung adenocarcinoma
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Includes: Supplementary data
Journal Articles

The inherited KRAS-variant as a biomarker of Cetuximab Response in NSCLC

Joanne B Weidhaas, Chen Hu, Ritsuko Komaki, Gregory A Masters, George R Blumenschein, Joe Y. Chang, Bo Lu, Adam P. Dicker, Jeffrey A Bogart, Yolanda I Garces, Samir Narayan, Clifford G. Robinson, Vivek S Kavadi, Joel S Greenberger, Christopher D Koprowski, James W. Welsh, Elizabeth Gore, Robert M MacRae, Rebecca Paulus, Jeffrey Bradley
Journal: Cancer Research Communications
Cancer Research Communications (2023)
https://doi.org/10.1158/2767-9764.CRC-23-0084
Published: 20 September 2023
View article titled, The inherited KRAS-variant as a biomarker of Cetuximab Response in NSCLC
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Includes: Supplementary data
Journal Articles

AKR1C3 Converts Castrate and Post-Abiraterone DHEA-S into Testosterone to Stimulate Growth of Prostate Cancer Cells via 5-Androstene-3β,17β-Diol

Andrea J. Detlefsen, Clementina A. Mesaros, Ling Duan, Trevor M. Penning
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (9): 1888–1898.
https://doi.org/10.1158/2767-9764.CRC-23-0235
Published: 19 September 2023
View article titled, AKR1C3 Converts Castrate and Post-Abiraterone DHEA-S into Testosterone to Stimulate Growth of Prostate Cancer Cells via 5-Androstene-3β,17β-Diol
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Includes: Supplementary data
Journal Articles

Integrated Molecular Characterization of Intraductal Papillary Mucinous Neoplasms: An NCI Cancer Moonshot Precancer Atlas Pilot Project

Alexander Semaan, Vincent Bernard, Justin W Wong, Yuki Makino, Daniel B Swartzlander, Kimal I. Rajapakshe, Jaewon J Lee, Adam Officer, C. Max Schmidt, Howard H Wu, Courtney L Scaife, Kajsa Affolter, Daniela Nachmanson, Matthew A. Firpo, Michele Yip-Schneider, Andrew M. Lowy, Olivier Harismendy, Subrata Sen, Anirban Maitra, Yasminka A Jakubek, Paola A. Guerrero
Journal: Cancer Research Communications
Cancer Research Communications (2023)
https://doi.org/10.1158/2767-9764.CRC-22-0419
Published: 18 September 2023
View article titled, Integrated Molecular Characterization of Intraductal Papillary Mucinous Neoplasms: An NCI Cancer Moonshot Precancer Atlas Pilot Project
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Includes: Supplementary data
Journal Articles

Targeting MALAT1 Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer.

Anjali Yadav, Tanay Biswas, Ayush Praveen, Promit Ganguly, Ankita Bhattacharyya, Ayushi Verma, Dipak Datta, Bushra Ateeq
Journal: Cancer Research Communications
Cancer Research Communications (2023)
https://doi.org/10.1158/2767-9764.CRC-23-0089
Published: 13 September 2023
View article titled, Targeting MALAT1 Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer.
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Includes: Supplementary data
Journal Articles

Combined targeting of NAD biosynthesis and the NAD-dependent transcription factor C-terminal Binding Protein as a promising novel therapy for pancreatic cancer

M. Michael Dcona, Kranthi Kumar Chougoni, Diana T. Dcona, Jacqueline L West, Sahib J. Singh, Keith C. Ellis, Steven R. Grossman
Journal: Cancer Research Communications
Cancer Research Communications (2023)
https://doi.org/10.1158/2767-9764.CRC-22-0521
Published: 13 September 2023
View article titled, Combined targeting of NAD biosynthesis and the NAD-dependent transcription factor C-terminal Binding Protein as a promising novel therapy for pancreatic cancer
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Includes: Supplementary data
Journal Articles

Serum Free Fatty Acid Changes Caused by High Expression of Stearoyl-CoA Desaturase 1 in Tumor Tissues Are Early Diagnostic Markers for Ovarian Cancer

Kanoko Katoh, Yuki Katoh, Akiko Kubo, Miho Iida, Yuji Ikeda, Takashi Iwata, Hiroshi Nishio, Masaki Sugawara, Daiki Kato, Makoto Suematsu, Shuichi Hirai, Kei Kawana
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (9): 1840–1852.
https://doi.org/10.1158/2767-9764.CRC-23-0138
Published: 13 September 2023
View article titled, Serum Free Fatty Acid Changes Caused by High Expression of Stearoyl-CoA Desaturase 1 in Tumor Tissues Are Early Diagnostic Markers for Ovarian Cancer
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Includes: Supplementary data
Journal Articles

Blood Leukocyte AHRR Methylation and Risk of Non–smoking-associated Cancer: A Case-cohort Study of Non–Hodgkin Lymphoma

Christina Dahl, Ulla A. Hvidtfeldt, Anne Tjønneland, Per Guldberg, Ole Raaschou-Nielsen
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (9): 1781–1787.
https://doi.org/10.1158/2767-9764.CRC-23-0151
Published: 07 September 2023
View article titled, Blood Leukocyte <em>AHRR</em> Methylation and Risk of Non–smoking-associated Cancer: A Case-cohort Study of Non–Hodgkin Lymphoma
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Journal Articles

A Druggable FOXA1-Glucocorticoid Receptor Transcriptional Axis Drives Tumor Growth in a Subset of Non-Small Cell Lung Cancer

M. Dorso, Payal T. Patel, Aleksandr Pankov, Jacob A. Boyer, Rajesh K. Soni, Isabella S. Del Priore, Omar Hayatt, Amanda Kulick, Connor J. Hagen, Elisa de Stanchina, Melissa R. Junttila, Anneleen Daemen, Lori S. Friedman, Ronald C. Hendrickson, Sarat Chandarlapaty
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (9): 1788–1799.
https://doi.org/10.1158/2767-9764.CRC-23-0310
Published: 07 September 2023
View article titled, A Druggable FOXA1-Glucocorticoid Receptor Transcriptional Axis Drives Tumor Growth in a Subset of Non-Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

PARP Inhibitors Effectively Reduce MAPK Inhibitor Resistant Melanoma Cell Growth and Synergize with MAPK Inhibitors through a Synthetic Lethal Interaction In Vitro and In Vivo

Lisa Marie Fröhlich, Heike Niessner, Birgit Sauer, Sofie Kämereit, Eftychia Chatziioannou, Simon Riel, Tobias Sinnberg, Birgit Schittek
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (9): 1743–1755.
https://doi.org/10.1158/2767-9764.CRC-23-0101
Published: 05 September 2023
View article titled, PARP Inhibitors Effectively Reduce MAPK Inhibitor Resistant Melanoma Cell Growth and Synergize with MAPK Inhibitors through a Synthetic Lethal Interaction <em>In Vitro</em> and <em>In Vivo</em>
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Includes: Supplementary data
Journal Articles

Single-cell Profiling Uncovers a Muc4-Expressing Metaplastic Gastric Cell Type Sustained by Helicobacter pylori-driven Inflammation

Valerie P. O'Brien, Yuqi Kang, Meera K. Shenoy, Greg Finak, William C. Young, Julien Dubrulle, Lisa Koch, Armando E. Rodriguez Martinez, Jeffery Williams, Elizabeth Donato, Surinder K. Batra, Cecilia C.S. Yeung, William M. Grady, Meghan A. Koch, Raphael Gottardo, Nina R. Salama
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (9): 1756–1769.
https://doi.org/10.1158/2767-9764.CRC-23-0142
Published: 05 September 2023
View article titled, Single-cell Profiling Uncovers a <em>Muc4</em>-Expressing Metaplastic Gastric Cell Type Sustained by <em>Helicobacter pylori</em>-driven Inflammation
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Includes: Supplementary data
Journal Articles

Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor

Shruti Lal, Neil E. Bhola, Bee-Chun Sun, Yuping Chen, Tom Huang, Vivian Morton, Kevin X. Chen, Shanghua Xia, Haoyu Zhang, Nehal S. Parikh, Qiuping Ye, O. Petter Veiby, David I. Bellovin, Yuhua Ji
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (9): 1731–1742.
https://doi.org/10.1158/2767-9764.CRC-23-0304
Published: 01 September 2023
View article titled, Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor
Open the PDF for Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor in another window
Includes: Supplementary data
Journal Articles

Demethylation of EHMT1/GLP Protein Reprograms Its Transcriptional Activity and Promotes Prostate Cancer Progression

Anna Besschetnova, Wanting Han, Mingyu Liu, Yanfei Gao, Muqing Li, Zifeng Wang, Maryam Labaf, Susan Patalano, Kavita Venkataramani, Rachel E. Muriph, Jill A. Macoska, Kellee R. Siegfried, Jason Evans, Steven P. Balk, Shuai Gao, Dong Han, Changmeng Cai
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (8): 1716–1730.
https://doi.org/10.1158/2767-9764.CRC-23-0208
Published: 31 August 2023
View article titled, Demethylation of EHMT1/GLP Protein Reprograms Its Transcriptional Activity and Promotes Prostate Cancer Progression
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Includes: Supplementary data
Journal Articles

Whole-genome CpG-resolution DNA Methylation Profiling of HNSCC Reveals Distinct Mechanisms of Carcinogenesis for Fine-scale HPV+ Cancer Subtypes

Tingting Qin, Shiting Li, Leanne E. Henry, Elysia Chou, Raymond G. Cavalcante, Bailey F. Garb, Nisha J. D'Silva, Laura S. Rozek, Maureen A. Sartor
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (8): 1701–1715.
https://doi.org/10.1158/2767-9764.CRC-23-0009
Published: 30 August 2023
View article titled, Whole-genome CpG-resolution DNA Methylation Profiling of HNSCC Reveals Distinct Mechanisms of Carcinogenesis for Fine-scale HPV+ Cancer Subtypes
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Includes: Supplementary data
Journal Articles

A Survey of Cancer Risk Behaviors, Beliefs, and Social Drivers of Health in New Hampshire and Vermont

Thomas A. Skipper, Julie E. Weiss, Heather A. Carlos, Christine M. Gunn, Rian M. Hasson, Janet L. Peacock, Jenna E. Schiffelbein, Anna N.A. Tosteson, Frederick Lansigan, Judy R. Rees
Journal: Cancer Research Communications
Cancer Research Communications (2023) 3 (8): 1678–1687.
https://doi.org/10.1158/2767-9764.CRC-23-0267
Published: 29 August 2023
View article titled, A Survey of Cancer Risk Behaviors, Beliefs, and Social Drivers of Health in New Hampshire and Vermont
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Includes: Supplementary data