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Research Article August 11 2022
A ketogenic diet in combination with gemcitabine increases survival in pancreatic cancer KPC mice
Natalia E. Cortez; Cecilia Rodriguez Lanzi; Brian V. Hong; Jihao Xu; Fangyi Wang; Shuai Chen; Jon J. Ramsey; Matthew G. Pontifex; Michael Müller; David Vauzour; Payam Vahmani; Chang-Il Hwang; Karen Matsukuma; Gerardo G. Mackenzie
Cancer Research Communications CRC-22-0256.
Research Article August 11 2022
SLFN11 negatively regulates non-canonical NF-kB signaling to promote glioblastoma progression
Mariafausta Fischietti; Frank Eckerdt; Ricardo E. Perez; Jamie N. Guillen Magaña; Candice Mazewski; Sang Ho; Christopher Gonzalez; Lukas D. Streich; Elspeth M. Beauchamp; Amy B. Heimberger; Aneta H. Baran; Feng Yue; C. David James; Leonidas C. Platanias
Cancer Research Communications CRC-22-0192.
Research Article August 11 2022
The Wnt pathway inhibitor RXC004 blocks tumor growth and reverses immune evasion in Wnt ligand-dependent cancer models
Caroline Phillips; Inder Bhamra; Catherine Eagle; Eimear Flanagan; Richard Armer; Clifford D. Jones; Matilda Bingham; Peter Calcraft; Alicia Edmenson Cook; Ben Thompson; Simon A. Woodcock
Cancer Research Communications CRC-21-0095.
Research Article August 9 2022
ZL-1211 exhibits robust anti-tumor activity by enhancing ADCC and activating NK cell-mediated inflammation in CLDN18.2-high and -low expressing gastric cancer models
Hiroyasu Konno; Tracey Lin; Renyi Wu; Xinchuan Dai; Shou Li; Grace Wang; Min Chen; Wenying Li; Lina Wang; Bee-Chun Sun; Zhen Luo; Tom Huang; Yuping Chen; John Zhang; Qiuping Ye; David Bellovin; Bing Wan; Lishan Kang; Christopher Szeto; Karl Hsu; Omar Kabbarah
Cancer Research Communications CRC-22-0216.
Research Article August 9 2022
An informatics bridge to improve the design and efficiency of Phase I clinical trials for anti-cancer drug combinations
Lei Wang; Lai Wei; Shijun Zhang; Lijun Cheng; Aditi Shendre; William E Carson; James L Chen; Dwight H Owen; Megan Gregory; Lang Li
Cancer Research Communications CRC-22-0160.
Research Article August 9 2022
Mavorixafor, an orally bioavailable CXCR4 antagonist, increases immune cell infiltration and inflammatory status of tumor microenvironment in patients with melanoma
Robert H.I. Andtbacka; Yan Wang; Robert H. Pierce; Jean S. Campbell; Melinda Yushak; Mohammed M Milhem; Merrick I. Ross; Kathleen Niland; Robert D Arbeit; Sudha Parasuraman; Kris Bickley; Cecilia Yeung; Lauri D Aicher; Kimberly S. Smythe; Lu Gan
Cancer Research Communications CRC-22-0090.
Research Article August 9 2022
Ribonuclease H2 subunit A preserves genomic integrity and promotes prostate cancer progression
Cancer Research Communications CRC-22-0126.
Research Article August 5 2022
Lung cancer patients of different racial backgrounds harbor distinct immune cell profiles
Yitian Xu; Licheng Zhang; Jose Thaiparambil; Sunny Mai; Dimuthu Nuwan Perera; Jilu Zhang; Ping-Ying Pan; Cristian Coarfa; Kenneth Ramos; Shu-Hsia Chen; Randa El-Zein
Cancer Research Communications CRC-22-0057.
Research Article August 1 2022
Na+/H+-exchanger 1 enhances antitumor activity of engineered NK-92 natural killer cells
Yao-Yu Gong; Hongguang Shao; Yu Li; Patricia Brafford; Zachary E. Stine; Jing Sun; Dean W. Felsher; Jordan S. Orange; Steven M. Albelda; Chi V. Dang
Cancer Research Communications CRC-22-0270.
Research Article July 29 2022
Repurposing azacitidine and carboplatin to prime immune checkpoint blockade-resistant melanoma for anti-PD-L1 re-challenge
Andre van der Westhuizen; Megan Lyle; Moira C. Graves; Xiaoqiang Zhu; Jason W.H. Wong; Kerrie Cornall; Shu Ren; Leanna Pugliese; Richard Levy; Adeeb J. Majid; Ricardo E. Vilain; Nikola A. Bowden
Cancer Research Communications CRC-22-0128.
Research Article July 28 2022
Brain neural progenitors are new predictive biomarkers for breast cancer hormonotherapy
Agnes Basseville; Chiara Cordier; Fadoua Ben Azzouz; Wilfried Gouraud; Hamza Lasla; Fabien Panloup; Mario Campone; Pascal Jézéquel
Cancer Research Communications CRC-21-0090.
Research Article July 26 2022
Persistent ethnicity-associated disparity in anti-tumor effectiveness of immune checkpoint inhibitors despite equal access
Marcus A. Florez; Jan Ole Kemnade; Nan Chen; Wendy Du; Anita L. Sabichi; Daniel Y. Wang; Quillan Huang; Courtney N. Miller-Chism; Aparna Jotwani; Albert C. Chen; David Hernandez; Vlad C. Sandulache
Cancer Research Communications CRC-21-0143.
Research Article July 25 2022
Distinct Predictive Immunogenomic Profiles of Response to Immune Checkpoint Inhibitors and IL-2: A Real-world Evidence Study of Patients with Advanced Renal Cancer
Joel R. Eisner; Kirk D. Beebe; Gregory M. Mayhew; Yoichiro Shibata; Yuelong Guo; Carol J. Farhangfar; Farhang Farhangfar; Joshua M. Uronis; Jill M. Mooney; Michael Milburn; David M. Foureau; Richard L. White; Asim Amin; Marcos E. Milla
Cancer Research Communications CRC-21-0153.
Research Article July 11 2022
Dietary Non-starch Polysaccharide Intake and Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study
Yi-Chuan Yu; Pedram Paragomi; Aizhen Jin; Renwei Wang; Robert E. Schoen; Woon-Puay Koh; Jian-Min Yuan; Hung N. Luu
Cancer Research Communications crc-22-0153.
Research Article June 28 2022
A TCR-like CAR promotes sensitive antigen recognition and controlled T cell expansion upon mRNA vaccination
Matthias Birtel; Ralf-Holger Voss; Katharina Reinhard; Benjamin Rengstl; Yasmina Ouchan; Kristina Michel; Nina Hayduk; Bodo Tillmann; René Becker; Martin Suchan; Matthias Theobald; Petra Oehm; Oezlem Tuereci; Ugur Sahin
Cancer Research Communications crcres.0154.2022.
