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KRAS Promotes GLI2-Dependent Transcription during Pancreatic Carcinogenesis
Ashley N. Sigafoos; Ezequiel J. Tolosa; Ryan M. Carr; Maite G. Fernandez-Barrena; Luciana L. Almada; David R. Pease; Tara L. Hogenson; Glancis L. Raja Arul; Fatemeh Mousavi; Sandhya Sen; Renzo E. Vera; David L. Marks; Luis F. Flores; Kayla C. LaRue-Nolan; Chen Wu; William R. Bamlet; Anne M. Vrabel; Hugues Sicotte; Erin L. Schenk; Thomas C. Smyrk; Lizhi Zhang; Kari G. Rabe; Ann L. Oberg; Peter G. Zaphiropoulos; Eric Chevet; Rondell P. Graham; Catherine E. Hagen; Marina P. di Magliano; Sherine F. Elsawa; Christopher L. Pin; Junhao Mao; Robert R. McWilliams; Martin E. Fernandez-Zapico
The Tumor Microbiome Reacts to Hypoxia and Can Influence Response to Radiation Treatment in Colorectal Cancer
Martin Benej; Rebecca Hoyd; McKenzie Kreamer; Caroline E. Wheeler; Dennis J. Grencewicz; Fouad Choueiry; Carlos H.F. Chan; Yousef Zakharia; Qin Ma; Rebecca D. Dodd; Cornelia M. Ulrich; Sheetal Hardikar; Michelle L. Churchman; Ahmad A. Tarhini; Lary A. Robinson; Eric A. Singer; Alexandra P. Ikeguchi; Martin D. McCarter; Gabriel Tinoco; Marium Husain; Ning Jin; Aik C. Tan; Afaf E.G. Osman; Islam Eljilany; Gregory Riedlinger; Bryan P. Schneider; Katarina Benejova; Martin Kery; Ioanna Papandreou; Jiangjiang Zhu; Nicholas Denko; Daniel Spakowicz; for the exORIEN Consortium
Race-Related Differences in Sipuleucel-T Response among Men with Metastatic Castrate–Resistant Prostate Cancer
Elisabeth I. Heath; Archana Thakur; Wei Chen; Clara Hwang; Channing J. Paller; Frank C. Cackowski; Julie L. Boerner; Lance Heilbrun; Melanie P. Smith; Dana L. Schalk; Amy Schienschang; Sarah A. Whitaker; Amanda Polend; Daryn Smith; Ulka N. Vaishampayan; Brenda Dickow; Lawrence G. Lum
Tumor-Immune Signatures of Treatment Resistance to Brentuximab Vedotin with Ipilimumab and/or Nivolumab in Hodgkin Lymphoma
Edgar Gonzalez-Kozlova; Hsin-Hui Huang; Opeyemi A. Jagede; Kevin Tuballes; Diane M. Del Valle; Geoffrey Kelly; Manishkumar Patel; Hui Xie; Jocelyn Harris; Kimberly Argueta; Kai Nie; Vanessa Barcessat; Radim Moravec; Jennifer Altreuter; Dzifa Y. Duose; Brad S. Kahl; Stephen M. Ansell; Joyce Yu; Ethan Cerami; James R. Lindsay; Ignacio I. Wistuba; Seunghee Kim-Schulze; Catherine S. Diefenbach; Sacha Gnjatic
Exploration of Immune-Modulatory Effects of Amivantamab in Combination with Pembrolizumab in Lung and Head and Neck Squamous Cell Carcinoma
Sun M. Lim; Seong-san Kang; Dong K. Kim; Soo-Hwan Lee; Chun-Bong Synn; Sujeong Baek; Seung M. Yang; Yu J. Han; Mi H. Kim; Heekyung Han; Kwangmin Na; Young T. Kim; Mi R. Yun; Jae H. Kim; Youngseon Byeon; Young S. Kim; Jii B. Lee; Min H. Hong; Joshua C. Curtin; Bharvin Patel; Isabelle Bergiers; Kyoung-Ho Pyo; Byoung C. Cho
Stratification to Neoadjuvant Radiotherapy in Rectal Cancer by Regimen and Transcriptional Signatures
Umair Mahmood; Andrew Blake; Sanjay Rathee; Leslie Samuel; Graeme Murray; David Sebag-Montefiore; Simon Gollins; Nicholas P. West; Rubina Begum; Simon P. Bach; Susan D. Richman; Phil Quirke; Keara L. Redmond; Manuel Salto-Tellez; Viktor H. Koelzer; Simon J. Leedham; Ian Tomlinson; Philip D. Dunne; Francesca M. Buffa; S:CORT consortium; Tim S. Maughan; Enric Domingo
Putrescine Supplementation Limits the Expansion of pks+ Escherichia coli and Tumor Development in the Colon
Manon Oliero; Thibault Cuisiniere; Ayodeji S. Ajayi; Claire Gerkins; Roy Hajjar; Gabriela Fragoso; Annie Calvé; Hervé Vennin Rendos; Annabelle Mathieu-Denoncourt; François Dagbert; Éric De Broux; Rasmy Loungnarath; Frank Schwenter; Herawaty Sebajang; Richard Ratelle; Ramses Wassef; Carole Richard; Marylise Duperthuy; Andrée E. Gravel; Antony T. Vincent; Manuela M. Santos
A Phase II Trial of the WEE1 Inhibitor Adavosertib in SETD2-Altered Advanced Solid Tumor Malignancies (NCI 10170)
Edward Maldonado; W. Kimryn Rathmell; Geoffrey I. Shapiro; Naoko Takebe; Jordi Rodon; Devalingam Mahalingam; Nikolaos A. Trikalinos; Arash R. Kalebasty; Mamta Parikh; Scott A. Boerner; Celene Balido; Gregor Krings; Timothy F. Burns; Emily K. Bergsland; Pamela N. Munster; Alan Ashworth; Patricia LoRusso; Rahul R. Aggarwal
N-Myristoytransferase Inhibition Causes Mitochondrial Iron Overload and Parthanatos in TIM17A-Dependent Aggressive Lung Carcinoma
Sofia Geroyska; Isabel Mejia; Alfred A. Chan; Marian Navarrete; Vijaya Pandey; Samuel Kharpatin; Juliana Noguti; Feng Wang; Daniel Srole; Tsui-Fen Chou; James Wohlschlegel; Elizabeta Nemeth; Robert Damoiseaux; David B. Shackelford; Delphine J. Lee; Begoña Díaz
Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Thomas J. Lai; Lu Sun; Kevin Li; Terry J. Prins; Janet Treger; Tie Li; Matthew Z. Sun; David A. Nathanson; Linda M. Liau; Albert Lai; Robert M. Prins; Richard G. Everson
A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC
Yusuke Goto; Keiichi Koshizuka; Toshinori Ando; Hiroki Izumi; Xingyu Wu; Kuniaki Sato; Tomohiko Ishikawa; Kyle Ford; Xiaodong Feng; Zhiyong Wang; Nadia Arang; Michael M. Allevato; Ayush Kishore; Prashant Mali; J. Silvio Gutkind
E2F1-Associated Purine Synthesis Pathway Is a Major Component of the MET-DNA Damage Response Network
Michaela Poliaková Turan; Rahel Riedo; Matúš Medo; Chiara Pozzato; Manja Friese-Hamim; Jonas P. Koch; Si’Ana A. Coggins; Qun Li; Baek Kim; Joachim Albers; Daniel M. Aebersold; Nicola Zamboni; Yitzhak Zimmer; Michaela Medová
Inhibition of Notch4 Using Novel Neutralizing Antibodies Reduces Tumor Growth in Murine Cancer Models by Targeting the Tumor Endothelium
Jason W.-L. Eng; Yu Kato; Yusuke Adachi; Bhairavi Swaminathan; L.A. Naiche; Rahul Vadakath; Yoshimasa Sakamoto; Youya Nakazawa; Sho Tachino; Ken Ito; Takanori Abe; Yukinori Minoshima; Kana Hoshino-Negishi; Hideaki Ogasawara; Tomomi Kawakatsu; Miyuki Nishimura; Masahiko Katayama; Masashi Shimizu; Kazuhiro Tahara; Toshitaka Sato; Katsuhisa Suzuki; Kishan Agarwala; Masao Iwata; Kenichi Nomoto; Yoichi Ozawa; Toshio Imai; Yasuhiro Funahashi; Junji Matsui; Jan Kitajewski
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