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A Pilot Study on Patient-specific Computational Forecasting of Prostate Cancer Growth during Active Surveillance Using an Imaging-informed Biomechanistic Model
Guillermo Lorenzo; Jon S. Heiselman; Michael A. Liss; Michael I. Miga; Hector Gomez; Thomas E. Yankeelov; Alessandro Reali; Thomas J.R. Hughes
Establishment and Characterization of an Epstein-Barr Virus–positive Cell Line from a Non-keratinizing Differentiated Primary Nasopharyngeal Carcinoma
Annie Wai Yeeng Chai; Shi Mun Yee; Hui Mei Lee; Norazlin Abdul Aziz; Pei San Yee; Marini Marzuki; Ka Wo Wong; Alan K.S. Chiang; Larry Ka-Yue Chow; Wei Dai; Teng Fei Liu; Lu Ping Tan; Alan Soo Beng Khoo; Kwok Wai Lo; Paul V.H. Lim; Pathmanathan Rajadurai; Howard Lightfoot; Syd Barthorpe; Mathew J. Garnett; Sok Ching Cheong
The NUTRIENT Trial (NUTRitional Intervention among myEloproliferative Neoplasms): Results from a Randomized Phase I Pilot Study for Feasibility and Adherence
Laura F. Mendez Luque; Julio Avelar-Barragan; Hellen Nguyen; Jenny Nguyen; Eli M. Soyfer; Jiarui Liu; Jane H. Chen; Nitya Mehrotra; Xin Huang; Heidi E. Kosiorek; Amylou Dueck; Alexander Himstead; Elena Heide; Melinda Lem; Kenza El Alaoui; Eduard Mas; Robyn M. Scherber; Ruben A. Mesa; Katrine L. Whiteson; Andrew Odegaard; Angela G. Fleischman
Single-Cell CD4 and CD8 T-Cell Secretome Profiling Reveals Temporal and Niche Differences in Acute Myeloid Leukemia Following Immune Checkpoint Blockade Therapy
Jessica L. Root; Poonam N. Desai; Christopher Ly; Bofei Wang; Fatima Zahra Jelloul; Jing Zhou; Sean Mackay; Mansour Alfayez; Jairo Matthews; Sherry Pierce; Patrick K. Reville; Naval Daver; Hussein A. Abbas
CALGB 80802 (Alliance): Impact of Sorafenib with and without Doxorubicin on Hepatitis C Infection in Patients with Advanced Hepatocellular Carcinoma
Ghassan K. Abou-Alfa; Susan M. Geyer; Andrew B. Nixon; Federico Innocenti; Qian Shi; Priya Kumthekar; Sawyer Jacobson; Imane El Dika; Amin Yaqubie; Juan Lopez; Binhui Huang; Yi-Wei Tang; Yujia Wen; Lawrence H. Schwartz; Anthony B. El-Khoueiry; Jennifer J. Knox; Lakshmi Rajdev; Monica M. Bertagnolli; Jeffrey A. Meyerhardt; Eileen M. O'Reilly; Alan P. Venook
Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation
Christopher Carroll; Auraya Manaprasertsak; Arthur Boffelli Castro; Hilda van den Bos; Diana C.J. Spierings; René Wardenaar; Anuraag Bukkuri; Niklas Engström; Etienne Baratchart; Minjun Yang; Andrea Biloglav; Charlie K. Cornwallis; Bertil Johansson; Catharina Hagerling; Marie Arsenian-Henriksson; Kajsa Paulsson; Sarah R. Amend; Sofie Mohlin; Floris Foijer; Alan McIntyre; Kenneth J. Pienta; Emma U. Hammarlund
Gigaxonin Suppresses Epithelial-to-Mesenchymal Transition of Human Cancer Through Downregulation of Snail
Mysore S. Veena; Jungmo J. Gahng; Mustafa Alani; Albert Y. Ko; Saroj K. Basak; Isabelle Y. Liu; Kimberly J. Hwang; Jenna R. Chatoff; Natarajan Venkatesan; Marco Morselli; Weihong Yan; Ibraheem Ali; Karolina Elżbieta Kaczor-Urbanowicz; Bhavani Shankara Gowda; Patrick Frost; Matteo Pellegrini; Neda A. Moatamed; Sharon P. Wilczynski; Pascale Bomont; Marilene B. Wang; Daniel Sanghoon Shin; Eri S. Srivatsan
Rejuvenated iPSC-derived GD2-directed CART Cells Harbor Robust Cytotoxicity Against Small Cell Lung Cancer
Shintaro Kinoshita; Midori Ishii; Jun Ando; Takaharu Kimura; Tomoyuki Yamaguchi; Sakiko Harada; Fumiyuki Takahashi; Kazutaka Nakashima; Yozo Nakazawa; Satoshi Yamazaki; Koichi Ohshima; Kazuhisa Takahashi; Hiromitsu Nakauchi; Miki Ando
Antibody–Drug Conjugate αEGFR-E-P125A Reduces Triple-negative Breast Cancer Vasculogenic Mimicry, Motility, and Metastasis through Inhibition of EGFR, Integrin, and FAK/STAT3 Signaling
Ankita P. Sankar; Hyun-Mi Cho; Seung-Uon Shin; Tal Sneh; Sundaram Ramakrishnan; Christian Elledge; Yu Zhang; Rathin Das; Hava Gil-Henn; Joseph D. Rosenblatt
Ex Vivo Efficacy of SAR442257 Anti-CD38 Trispecific T-cell Engager in Multiple Myeloma Relapsed After Daratumumab and BCMA-targeted Therapies
Alana L. Keller; Lauren T. Reiman; Olivia Perez de Acha; Sarah E. Parzych; Peter A. Forsberg; Peter S. Kim; Kamlesh Bisht; Hongfang Wang; Helgi van de Velde; Daniel W. Sherbenou
Correction: Combination of Itacitinib or Parsaclisib with Pembrolizumab in Patients with Advanced Solid Tumors: A Phase I Study
Pamela Munster; Nicholas Iannotti; Daniel C. Cho; John M. Kirkwood; Liza C. Villaruz; Geoffrey T. Gibney; F. Stephen Hodi; Niharika B. Mettu; Mark Jones; Jill Bowman; Michael Smith; Mani Lakshminarayanan; Steven O'Day
Impact of Tumor-intrinsic Molecular Features on Survival and Acquired Tyrosine Kinase Inhibitor Resistance in ALK-positive NSCLC
Mari Nakazawa; Guilherme Harada; Paola Ghanem; Adrian Bubie; Lesli A. Kiedrowski; Joseph C. Murray; Kristen A. Marrone; Susan C. Scott; Stefanie Houseknecht; Christina J. Falcon; Patrick Evans; Josephine Feliciano; Christine L. Hann; David S. Ettinger; Kellie N. Smith; Valsamo Anagnostou; Patrick M. Forde; Julie R. Brahmer; Benjamin Levy; Alexander Drilon; Vincent K. Lam
Nanoparticle-mediated Photodynamic Therapy as a Method to Ablate Oral Cavity Squamous Cell Carcinoma in Preclinical Models
Axel Sahovaler; Michael S. Valic; Jason L. Townson; Harley H.L. Chan; Mark Zheng; Sharon Tzelnick; Tiziana Mondello; Alon Pener-Tessler; Donovan Eu; Abdullah El-Sayes; Lili Ding; Juan Chen; Catriona M. Douglas; Robert Weersink; Nidal Muhanna; Gang Zheng; Jonathan C. Irish
Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer
Shama Karanth; Oyomoare L. Osazuwa-Peters; Lauren E. Wilson; Rebecca A. Previs; Fariha Rahman; Bin Huang; Maria Pisu; Margaret Liang; Kevin C. Ward; Maria J. Schymura; Andrew Berchuck; Tomi F. Akinyemiju
Targeting Tryptophan Catabolism in Ovarian Cancer to Attenuate Macrophage Infiltration and PD-L1 Expression
Lyndsey S. Crump; Jessica L. Floyd; Li-Wei Kuo; Miriam D. Post; Mike Bickerdike; Kathleen O'Neill; Kayla Sompel; Kimberly R. Jordan; Bradley R. Corr; Nicole Marjon; Elizabeth R. Woodruff; Jennifer K. Richer; Benjamin G. Bitler
Activity of the Ubiquitin-activating Enzyme Inhibitor TAK-243 in Adrenocortical Carcinoma Cell Lines, Patient-derived Organoids, and Murine Xenografts
Yasuhiro Arakawa; Ukhyun Jo; Suresh Kumar; Nai-Yun Sun; Fathi Elloumi; Anish Thomas; Nitin Roper; Diana Grace Varghese; Naoko Takebe; Xiaohu Zhang; Michele Ceribelli; David O. Holland; Erin Beck; Zina Itkin; Crystal McKnight; Kelli M. Wilson; Jameson Travers; Carleen Klumpp-Thomas; Craig J. Thomas; Chuong D. Hoang; Jonathan M. Hernandez; Jaydira Del Rivero; Yves Pommier
Immune Profiling of Vulvar Squamous Cell Cancer Discovers a Macrophage-rich Subtype Associated with Poor Prognosis
Mateja Condic; Andrea Rohr; Soheila Riemann; Christian Staerk; Tiyasha H. Ayub; Anna Doeser; Thomas Zillinger; Sabine Merkelbach-Bruse; Reinhard Buettner; Winfried Barchet; Christian Rudlowski; Alexander Mustea; Kirsten Kübler
D-2-HG Inhibits IDH1mut Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation
Sean T. Pianka; Tie Li; Terry J. Prins; Blaine S.C. Eldred; Bryan M. Kevan; Haowen Liang; Serendipity Zapanta Rinonos; Harley I. Kornblum; David A. Nathanson; Matteo Pellegrini; Linda M. Liau; Phioanh Leia Nghiemphu; Timothy F. Cloughesy; Albert Lai
Tumor Microenvironment Landscapes Supporting EGFR-mutant NSCLC Are Modulated at the Single-cell Interaction Level by Unesbulin Treatment
Giorgia Maroni; Indira Krishnan; Roberta Alfieri; Valerie A. Maymi; Nicole Pandell; Eva Csizmadia; Junyan Zhang; Marla Weetall; Art Branstrom; Giulia Braccini; Eva Cabrera San Millán; Barbara Storti; Ranieri Bizzarri; Olivier Kocher; Daniela S. Daniela Sanchez Bassères; Robert S. Welner; Maria Cristina Magli; Ivan Merelli; John G. Clohessy; Azhar Ali; Daniel G. Tenen; Elena Levantini
High-resolution Diffusion-weighted Imaging to Detect Changes in Tumor Size and ADC, and Predict Adverse Biopsy Histology during Prostate Cancer Active Surveillance
Rola Saouaf; Yibin Xie; Sungjin Kim; Yaniv Raphael; Christopher Nguyen; Daniel Luthringer; Timothy J. Daskivich; Eric Lo; Mourad Tighiouart; Debiao Li; Hyung L. Kim
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NOTICE: This notice serves to inform the reader that, in 2023, AACR received a donation by Pfizer of the rights to royalties from the sale—within the United States—of Bavencio® (avelumab), a pharmaceutical owned by Merck. None of these funds are being, or will be, used to directly support any specific publication or author. If an individual article is published that deals with this particular drug, such article will include standard financial disclosures per AACR journal policy. For more detail regarding AACR’s established policies for authors, please go to https://aacrjournals.org/pages/editorial-policies#coi.