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CAR T-cell Design-dependent Remodeling of the Brain Tumor Immune Microenvironment Modulates Tumor-associated Macrophages and Anti-glioma Activity
Dalia Haydar; Jorge Ibañez-Vega; Jeremy Chase Crawford; Ching-Heng Chou; Clifford S. Guy; Michaela Meehl; Zhongzhen Yi; Scott Perry; Jonathan Laxton; Trevor Cunningham; Deanna Langfitt; Peter Vogel; Christopher DeRenzo; Stephen Gottschalk; Martine F. Roussel; Paul G. Thomas; Giedre Krenciute
Phase Ib Trial of Phenformin in Patients with V600-mutated Melanoma Receiving Dabrafenib and Trametinib
Paul B. Chapman; Mark Klang; Michael A. Postow; Alexander Noor Shoushtari; Ryan J. Sullivan; Jedd D. Wolchok; Taha Merghoub; Sadna Budhu; Phillip Wong; Margaret K. Callahan; Bin Zheng; Jonathan Zippin
Temporary Knockdown of p53 During Focal Limb Irradiation Increases the Development of Sarcomas
Andrea R. Daniel; Chang Su; Nerissa T. Williams; Zhiguo Li; Jianguo Huang; Omar Lopez; Lixia Luo; Yan Ma; Lorraine da Silva Campos; Sara R. Selitsky; Jennifer L. Modliszewski; Siyao Liu; Rosa Hernansaiz-Ballesteros; Yvonne M. Mowery; Diana M. Cardona; Chang-Lung Lee; David G. Kirsch
Longitudinal Natural History Study of Children and Adults with Rare Solid Tumors: Initial Results for First 200 Participants
Shadin Ahmed; Mary Frances Wedekind; Jaydira Del Rivero; Margarita Raygada; Robin Lockridge; John W. Glod; Crystal Flowers; BJ Thomas; Donna B. Bernstein; Oxana B. Kapustina; Ashish Jain; Markku Miettinen; Mark Raffeld; Liqiang Xi; Manoj Tyagi; Jung Kim; Kenneth Aldape; Ashkan A. Malayeri; Rosandra N. Kaplan; Taryn Allen; Christina A. Vivelo; Abby B. Sandler; Brigitte C. Widemann; Karlyne M. Reilly; for the MyPART network
Integrin-αvβ3 is a Therapeutically Targetable Fundamental Factor in Medulloblastoma Tumorigenicity and Radioresistance
William Echavidre; Jérôme Durivault; Célia Gotorbe; Thays Blanchard; Marina Pagnuzzi; Valérie Vial; Florian Raes; Alexis Broisat; Rémy Villeneuve; Régis Amblard; Nicolas Garnier; Cécile Ortholan; Marc Faraggi; Benjamin Serrano; Vincent Picco; Christopher Montemagno
Statin-induced Mitochondrial Priming Sensitizes Multiple Myeloma Cells to BCL2 and MCL-1 Inhibitors
Dennis Juarez; Roberta Buono; Shannon M. Matulis; Vikas A. Gupta; Madeleine Duong; Jacob Yudiono; Madhuri Paul; Sharmila Mallya; Grace Diep; Peter Hsin; Alexander Lu; Sang Mi Suh; Vy M. Dong; Andrew W. Roberts; Joel D. Leverson; Muhammad Jalaluddin; Zhuangzhuang Liu; Orlando F. Bueno; Lawrence H. Boise; David A. Fruman
Sustained Disease Control in Immune Checkpoint Blockade Responders with Microsatellite Instability-high Colorectal Cancer after Treatment Termination
Kristen Simmons; Jane V. Thomas; Kaysia Ludford; Jason A. Willis; Victoria S. Higbie; Kanwal P.S. Raghav; Benny Johnson; Arvind Dasari; Bryan K. Kee; Christine M. Parseghian; Michael S. Lee; Phat H. Le; Maria P. Morelli; John Paul Shen; Alisha Bent; Eduardo Vilar; Robert A. Wolff; Scott Kopetz; Michael J. Overman; Van Karlyle Morris
Monitoring Glucocorticoid Receptor in Plasma-derived Extracellular Vesicles as a Marker of Resistance to Androgen Receptor Signaling Inhibition in Prostate Cancer
Emanuela Gentile; Andrew W. Hahn; Jian H. Song; Anh Hoang; Peter D. A. Shepherd; Sumankalai Ramachandran; Nora M. Navone; Eleni Efstathiou; Mark Titus; Paul G. Corn; Sue-Hwa Lin; Christopher J. Logothetis; Theocharis Panaretakis
Polygenic Risk Score Modifies Prostate Cancer Risk of Pathogenic Variants in Men of African Ancestry
Raymond W. Hughley; Marco Matejcic; Ziwei Song; Xin Sheng; Peggy Wan; Lucy Xia; Steven N. Hart; Chunling Hu; Siddhartha Yadav; Alexander Lubmawa; Vicky Kiddu; Frank Asiimwe; Colline Amanya; George Mutema; Kuteesa Job; Mbaaga K. Ssebakumba; Sue A. Ingles; Ann S. Hamilton; Fergus J. Couch; Stephen Watya; David V. Conti; Burcu F. Darst; Christopher A. Haiman
Clinical Outcomes and Evolution of Clonal Hematopoiesis in Patients with Newly Diagnosed Multiple Myeloma
Tarek H. Mouhieddine; Chidimma Nzerem; Robert Redd; Andrew Dunford; Matthew Leventhal; Romanos Sklavenitis-Pistofidis; Sabrin Tahri; Habib El-Khoury; David P. Steensma; Benjamin L. Ebert; Robert J. Soiffer; Jonathan J. Keats; Shaadi Mehr; Daniel Auclair; Irene M. Ghobrial; Adam S. Sperling; Chip Stewart; Gad Getz
Combination of Itacitinib or Parsaclisib with Pembrolizumab in Patients with Advanced Solid Tumors: A Phase I Study
Pamela Munster; Nicholas Iannotti; Daniel C. Cho; John M. Kirkwood; Liza C. Villaruz; Geoffrey T. Gibney; F. Stephen Hodi; Niharika B. Mettu; Mark Jones; Jill Bowman; Michael Smith; Mani Lakshminarayanan; Steven O'Day
Immunologic Signatures of Peripheral Blood T Cells Reveal the Outcome of p53MVA Vaccine and Pembrolizumab Treatment in Patients with Advanced Ovarian Cancer
Ferdynand J. Kos; Paul Frankel; Mihaela Cristea; Melissa Eng; Raechelle Tinsley; Shannon Dempsey; Nora Ruel; Daphne Stewart; Thanh H. Dellinger; Don J. Diamond
Discovery of KRB-456, a KRAS G12D Switch-I/II Allosteric Pocket Binder That Inhibits the Growth of Pancreatic Cancer Patient-derived Tumors
Aslamuzzaman Kazi; Alok Ranjan; Vasantha Kumar M.V.; Bogos Agianian; Martin Garcia Chavez; Vignesh Vudatha; Rui Wang; Rajanikanth Vangipurapu; Liwei Chen; Perry Kennedy; Karthikeyan Subramanian; Jonathan C.K. Quirke; Francisca Beato; Patrick W. Underwood; Jason B. Fleming; Jose Trevino; Paul J. Hergenrother; Evripidis Gavathiotis; Said M. Sebti
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