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Zoltan Szallasi
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Journal Articles

Genetic Determinants of Somatic Selection of Mutational Processes in 3,566 Human Cancers

Jintao Guo, Ying Zhou, Chaoqun Xu, Qinwei Chen, Zsófia Sztupinszki, Judit Börcsök, Canqiang Xu, Feng Ye, Weiwei Tang, Jiapeng Kang, Lu Yang, Jiaxin Zhong, Taoling Zhong, Tianhui Hu, Rongshan Yu, Zoltan Szallasi, Xianming Deng, Qiyuan Li
Journal: Cancer Research
Cancer Res (2021) 81 (16): 4205–4217.
https://doi.org/10.1158/0008-5472.CAN-21-0086
Published: 15 August 2021
View article titled, Genetic Determinants of Somatic Selection of Mutational Processes in 3,566 Human Cancers
Open the PDF for Genetic Determinants of Somatic Selection of Mutational Processes in 3,566 Human Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract 2526: PMEPA1 gene isoforms indicated aggressive disease progression in non-prostate solid tumors

Shashwat Sharad, Zsófia M. Sztupinszki, Zoltan Szallasi, Shiv Srivastava, Alagarsamy Srinivasan, Albert Dobi, Hua Li
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2526.
https://doi.org/10.1158/1538-7445.AM2021-2526
Published: 01 July 2021
View article titled, Abstract 2526: PMEPA1 gene isoforms indicated aggressive disease progression in non-prostate solid tumors
Journal Articles

Abstract 2678: A clonal expression biomarker improves prognostic accuracy: TRACERx lung

Dhruva Biswas, Nicolai J. Birkbak, Rachel Rosenthal, Crispin T. Hiley, Emilia L. Lim, Krisztian Papp, Marcin Krzystanek, Dijana Djureinovic, Yin Wu, David A. Moore, Marcin Skrypski, Christopher Abbosh, Maise Al Bakir, Thomas B. Watkins, Selvaraju Veeriah, Gareth A. Wilson, Mariam Jamal-Hanjani, Arul M. Chinnaiyan, Patrick Micke, Jiri Bartek, Istvan Csabai, Zoltan Szallasi, Javier Herrero, Nicholas McGranahan, Charles Swanton
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2678.
https://doi.org/10.1158/1538-7445.AM2019-2678
Published: 01 July 2019
View article titled, Abstract 2678: A clonal expression biomarker improves prognostic accuracy: TRACERx lung
Journal Articles

Abstract 2626: Exquisite specificity of PMEPA1 isoforms in regulation of androgen signaling through AR protein degradation in prostate cancer

Shashwat Sharad, Natashia Benjamin, Zsófia Sztupinszki, Zoltan Szallasi, Shiv Srivastava, Inger L. Rosner, Jennifer Cullen, Hua Li, Albert Dobi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2626.
https://doi.org/10.1158/1538-7445.AM2019-2626
Published: 01 July 2019
View article titled, Abstract 2626: Exquisite specificity of <em>PMEPA1</em> isoforms in regulation of androgen signaling through AR protein degradation in prostate cancer
Journal Articles

Abstract A018: Distinct genomic alterations in prostate cancer of African American men

Albert Dobi, Gyorgy Petrovics, Hua Li, Denise Young, Shyh-Han Tan, Yongmei Chen, Qingyu Xiao, Yidi Sun, Hong Li, Yixue Li, Yuan Ji, Jun Hou, Wendy Wang, Jacob Kagan, Guo-Ping Zhao, Sudhir Srivastava, Reinhard Ebner, Inger L. Rosner, Jennifer Cullen, Matthew Freedman, Isabell Sesterhenn, Zoltan Szallasi, Shiv Srivastava
Journal: Cancer Research
Cancer Res (2018) 78 (16_Supplement): A018.
https://doi.org/10.1158/1538-7445.PRCA2017-A018
Published: 14 August 2018
View article titled, Abstract A018: Distinct genomic alterations in prostate cancer of African American men
Journal Articles

Abstract 4613: The difference of molecular signatures in left- and right-sided colorectal cancer Chinese patients

Sen Zhang, Yun Guo, Weibin Shu, Hui Li, Yu Wang, Wei Zhao, Zusen Wang, Xueqing Yao, Tao Xiang, Yong Li, Ting Deng, Ruobing Ma, Qiang Cui, Lei Mei, Yang Lou, Shuo Mu, Zoltan Szallasi, Yongchang Zhang, Ming Yao, Kai Wang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4613.
https://doi.org/10.1158/1538-7445.AM2018-4613
Published: 01 July 2018
View article titled, Abstract 4613: The difference of molecular signatures in left- and right-sided colorectal cancer Chinese patients
Journal Articles

Abstract 5352: Racial/ethnic differences in prostate cancer genomic alterations

Albert Dobi, Gyorgy Petrovics, Shyh-Han Tan, Hua Li, Denise Young, Cara Schafer, Jesse Fox, Kevin Babcock, Heng-Cheng Hu, Gauthaman Sukumar, Yingjie Song, Lakshmi Ravindranath, Yongmei Chen, Joseph Cheng, Reinhard Ebner, Qingyu Xiao, Yidi Sun, Yixue Li, Yuan Ji, Jun Hou, Wendy Wang, Guo-Ping Zhao, Jacob Kagan, Sudhir Srivastava, Joel T. Moncur, Clifton L. Dalgard, Matthew Wilkerson, Inger L. Rosner, Jennifer Cullen, Matthew Freedman, Zoltan Szallasi, Isabell A. Sesterhenn, Shiv Srivastava
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5352.
https://doi.org/10.1158/1538-7445.AM2018-5352
Published: 01 July 2018
View article titled, Abstract 5352: Racial/ethnic differences in prostate cancer genomic alterations
Journal Articles

Abstract 140: LSAMP gene deletion is associated with rapid disease progression in prostate cancer of African American men

Albert Dobi, Gyorgy Petrovics, Hua Li, Shyh-Han Tan, Tanja Stümpel, Denise Young, Shilpa Katta, Qiyuan Li, Kai Ying, Bernward Klocke, Lakshmi Ravindranath, Indu Kohaar, Yongmei Chen, Dezső Ribli, Korbinian Grote, Hau Zou, Joseph Cheng, Clifton L. Dalgard, Shimin Zhang, István Csabai, Jacob Kagan, David Takeda, Massimo Loda, Sudhir Srivastava, Matthias Scherf, Martin Seifert, Timo Gaiser, David G. McLeod, Zoltan Szallasi, Reinhard Ebner, Thomas Werner, Isabell A. Sesterhenn, Matthew Freedman, Shiv Srivastava
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 140.
https://doi.org/10.1158/1538-7445.AM2016-140
Published: 15 July 2016
View article titled, Abstract 140: LSAMP gene deletion is associated with rapid disease progression in prostate cancer of African American men
Journal Articles

Abstract 2027: MECP2 is a frequently amplified oncogene with an unusual epigenetic mechanism of action

Manish Neupane, Allison P. Clark, Nicolai J. Birkbak, Aron Eklund, Steven E. Schumacher, Rameen Beroukhim, Zoltan Szallasi, Marc Vidal, David E. Hill, Daniel P. Silver
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2027.
https://doi.org/10.1158/1538-7445.AM2015-2027
Published: 01 August 2015
View article titled, Abstract 2027: MECP2 is a frequently amplified oncogene with an unusual epigenetic mechanism of action
Journal Articles

Abstract P3-06-11: Homologous recombination deficiency (HRD) assay predicts response to cisplatin neoadjuvant chemotherapy in patients with triple negative breast cancer

Andrea L Richardson, Daniel P Silver, Zoltan Szallasi, Nicolai J Birkbak, Zhigang C Wang, J Dirk Iglehart, Erica L Mayer, Eric P Winer, Nadine M Tung, Paula D Ryan, Steven J Isakoff, William T Barry, April Greene-Collozi, Alexander Gutin, Julia Reid, Chris Neff, Joshua Jones, Kirsten Timms, Anne-Renee Hartman, Judy E Garber
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P3-06-11.
https://doi.org/10.1158/1538-7445.SABCS14-P3-06-11
Published: 01 May 2015
View article titled, Abstract P3-06-11: Homologous recombination deficiency (HRD) assay predicts response to cisplatin neoadjuvant chemotherapy in patients with triple negative breast cancer
Journal Articles

Abstract 2822: A pan-cancer analysis of inferred homologous recombination deficiency identifies potential platinum benefit in novel subtypes

Andrea M. Marquard, Aron C. Eklund, Zhigang C. Wang, Andrea L. Richardson, Zoltan Szallasi, Nicolai J. Birkbak
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2822.
https://doi.org/10.1158/1538-7445.AM2014-2822
Published: 01 October 2014
View article titled, Abstract 2822: A pan-cancer analysis of inferred homologous recombination deficiency identifies potential platinum benefit in novel subtypes
Journal Articles

Abstract 1192: Establishment and characterization of a new patient-derived renal cell carcinoma xenograft panel

Susanne Flechsig, Annika Wulf-Goldenberg, Christian Schmees, Burkhard Jandrig, Jörg Hennenlotter, Jens Bedke, Martin Schostak, Andrew Crockford, Marco Gerlinger, James Larkin, Charles Swanton, Zoltan Szallasi, Iduna Fichtner, Jens Hoffmann
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1192.
https://doi.org/10.1158/1538-7445.AM2014-1192
Published: 01 October 2014
View article titled, Abstract 1192: Establishment and characterization of a new patient-derived renal cell carcinoma xenograft panel
Journal Articles

Abstract 4603: Intratumor heterogeneity in clear cell renal cell carcinoma (ccRCC): Multi-region sequencing redefines the mutational landscape of ccRCCs.

Marco Gerlinger, Stuart Horswell, James Larkin, Andrew J. Rowan, Pierre Martinez, Ignacio Varela, Claudio R. Santos, Rosalie Fisher, Max P. Salm, Zoltan Szallasi, Nicholas Matthews, Aengus Stewart, P Andrew Futreal, Charles Swanton
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4603.
https://doi.org/10.1158/1538-7445.AM2013-4603
Published: 15 April 2013
View article titled, Abstract 4603: Intratumor heterogeneity in clear cell renal cell carcinoma (ccRCC): Multi-region sequencing redefines the mutational landscape of ccRCCs.
Journal Articles

Abstract LB-255: Exome mutation burden predicts clinical outcome in ovarian cancer carrying mutated BRCA1 and BRCA2 genes.

Nicolai Juul Birkbak, Bose Kochupurakkal, Jose MG Izarzugaza, Yang Li, Joyce Liu, Zoltan Szallasi, Ursula Matulonis, Andrea L. Richardson, J Dirk Iglehart, Zhigang C. Wang
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-255.
https://doi.org/10.1158/1538-7445.AM2013-LB-255
Published: 15 April 2013
View article titled, Abstract LB-255: Exome mutation burden predicts clinical outcome in ovarian cancer carrying mutated BRCA1 and BRCA2 genes.
Journal Articles

Abstract 964: Intra-tumor heterogeneity and Darwinian selection revealed by multi-region exome sequencing of renal cell carcinomas

Marco Gerlinger, Andrew Rowan, Stuart Horswell, James Larkin, David Endesfelder, Eva Gronroos, Pierre Martinez, Nicholas Matthews, Aengus Stewart, Patrick Tarpey, Ignacio Varela, Benjamin Phillimore, Sharmin Begum, Neil McDonald, Adam Butler, David Jones, Keiran Raine, Calli Latimer, Claudio Santos, Mahrokh Nohadani, Aron Eklund, Bradley Spencer-Dene, Graham Clark, Lisa Pickering, Gordon Stamp, Martin Gore, Zoltan Szallasi, Julian Downward, P Andrew Futreal, Charles Swanton
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 964.
https://doi.org/10.1158/1538-7445.AM2012-964
Published: 15 April 2012
View article titled, Abstract 964: Intra-tumor heterogeneity and Darwinian selection revealed by multi-region exome sequencing of renal cell carcinomas
Journal Articles

Abstract 4823: Copy number gain and increased expression of BLM and FANCI is associated with sensitivity to genotoxic chemotherapy in triple negative breast and serous ovarian cancer

Nicolai J. Birkbak, Yang Li, Zhigang C. Wang, Daniel P. Silver, James D. Iglehart, Judy E. Garber, Zoltan Szallasi, Andrea L. Richardson
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4823.
https://doi.org/10.1158/1538-7445.AM2012-4823
Published: 15 April 2012
View article titled, Abstract 4823: Copy number gain and increased expression of BLM and FANCI is associated with sensitivity to genotoxic chemotherapy in triple negative breast and serous ovarian cancer
Journal Articles

Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer

Nicolai J. Birkbak, Aron C. Eklund, Qiyuan Li, Sarah E. McClelland, David Endesfelder, Patrick Tan, Iain B. Tan, Andrea L. Richardson, Zoltan Szallasi, Charles Swanton
Journal: Cancer Research
Cancer Res (2011) 71 (10): 3447–3452.
https://doi.org/10.1158/0008-5472.CAN-10-3667
Published: 15 May 2011
View article titled, Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer
Open the PDF for Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer in another window
Includes: Supplementary data
Journal Articles

Chromosomal Instability Confers Intrinsic Multidrug Resistance

Alvin J.X. Lee, David Endesfelder, Andrew J. Rowan, Axel Walther, Nicolai J. Birkbak, P. Andrew Futreal, Julian Downward, Zoltan Szallasi, Ian P.M. Tomlinson, Michael Howell, Maik Kschischo, Charles Swanton
Journal: Cancer Research
Cancer Res (2011) 71 (5): 1858–1870.
https://doi.org/10.1158/0008-5472.CAN-10-3604
Published: 01 March 2011
View article titled, Chromosomal Instability Confers Intrinsic Multidrug Resistance
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Includes: Supplementary data
Journal Articles

Validating predictive profiles in HER2 positive early stage breast cancer using RNA microarray

Fanglei You, Scott Carter, Aron Eklund, J. D. Iglehart, Dennis Sgroi, Andrea Richardson, Zoltan Szallasi, Lyndsay N. Harris
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 442–443.
Published: 01 May 2005
View article titled, Validating predictive profiles in HER2 positive early stage breast cancer using RNA microarray
Journal Articles

Simultaneous Suppression of Epidermal Growth Factor Receptor and c-erbB-2 Reverses Aneuploidy and Malignant Phenotype of a Human Ovarian Carcinoma Cell Line

Svetlana D. Pack, Özgül M. Alper, Kurt Stromberg, Meena Augustus, Metin Özdemirli, Anne M. Miermont, Greg Klus, Marek Rusin, Rebecca Slack, Neville F. Hacker, Thomas Ried, Zoltan Szallasi, Özge Alper
Journal: Cancer Research
Cancer Res (2004) 64 (3): 789–794.
https://doi.org/10.1158/0008-5472.CAN-03-1982
Published: 10 February 2004
View article titled, Simultaneous Suppression of Epidermal Growth Factor Receptor and c-erbB-2 Reverses Aneuploidy and Malignant Phenotype of a Human Ovarian Carcinoma Cell Line
Open the PDF for Simultaneous Suppression of Epidermal Growth Factor Receptor and c-erbB-2 Reverses Aneuploidy and Malignant Phenotype of a Human Ovarian Carcinoma Cell Line in another window
Includes: Supplementary data