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Journal Articles

Cancer Etiology and Prevention Principle: “1 + X”

Hui Liu, Zigang Dong

Cancer Res (2021) 81 (21): 5377–5395.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-1862

Published: 01 November 2021

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Includes: Supplementary data

Journal Articles

GSK3β-Mediated Expression of CUG-Translated WT1 Is Critical for Tumor Progression

Hisae Yoshitomi, Kun Y. Lee, Ke Yao, Seung Ho Shin, Tianshun Zhang, Qiushi Wang, Souren Paul, Eunmiri Roh, Joohyun Ryu, Hanyong Chen, Faisal Aziz, Abhijit Chakraborty, Ann M. Bode, Zigang Dong

Cancer Res (2021) 81 (4): 945–955.

DOI: https://doi.org/10.1158/0008-5472.CAN-20-1880

Published: 15 February 2021

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Includes: Supplementary data

Journal Articles

Targeting CDK12 for Cancer Therapy: Function, Mechanism, and Drug Discovery

Hui Liu, Kangdong Liu, Zigang Dong

Cancer Res (2021) 81 (1): 18–26.

DOI: https://doi.org/10.1158/0008-5472.CAN-20-2245

Published: 04 January 2021

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Includes: Supplementary data

Journal Articles

ARC Is a Critical Protector against Inflammatory Bowel Disease (IBD) and IBD-Associated Colorectal Tumorigenesis

Qiushi Wang, Tianshun Zhang, Xiaoyu Chang, Do Young Lim, Keke Wang, Ruihua Bai, Ting Wang, Joohyun Ryu, Hanyong Chen, Ke Yao, Wei-Ya Ma, Lisa A. Boardman, Ann M. Bode, Zigang Dong

Cancer Res (2020) 80 (19): 4158–4171.

DOI: https://doi.org/10.1158/0008-5472.CAN-20-0469

Published: 02 October 2020

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Includes: Supplementary data

Journal Articles

Abstract 422: IL-10 inhibition accelerates gastric tumorigenesis in mice with either Helicobacter pylori infection or chronic alcohol intake

Faisal aziz, Ann Bode, Zigang Dong

Cancer Res (2020) 80 (16_Supplement): 422.

DOI: https://doi.org/10.1158/1538-7445.AM2020-422

Published: 15 August 2020

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Journal Articles

Abstract 5810: Fyn kinase negatively regulates telomere length in stem cells and cancer cells

Souren Paul, Thi My Le Le, Joohyun Ryu, Ki Beom Bae, Ann M. Bode, Zigang Dong

Cancer Res (2020) 80 (16_Supplement): 5810.

DOI: https://doi.org/10.1158/1538-7445.AM2020-5810

Published: 15 August 2020

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Journal Articles

Abstract 6380: Suppression of the solar ultraviolet-induced skin carcinogenesis by TOPK inhibitor HI-TOPK-032

Eunmiri Roh, Yaping Han, Kanamata Reddy, Tatyana A. Zykova, Mee Hyun Lee, Ke Yao, Ruihua Bai, Clara Curiel-Lewandrowski, Zigang Dong

Cancer Res (2020) 80 (16_Supplement): 6380.

DOI: https://doi.org/10.1158/1538-7445.AM2020-6380

Published: 15 August 2020

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Journal Articles

Abstract 1443: Inhibiting HMG-CoA reductase suppresses non-small cell lung carcinogenesis

Qiushi Wang, Tianshun Zhang, Ruihua Bai, Keke Wang, Xiang Li, Kangdong Liu, Ting Wang, Xiaoyu Chang, Weiya Ma, Ann Bode, Qingxin Xia, Yongping Song, Zigang Dong

Cancer Res (2020) 80 (16_Supplement): 1443.

DOI: https://doi.org/10.1158/1538-7445.AM2020-1443

Published: 15 August 2020

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Journal Articles

Abstract 2469: RCC2 promotes esophageal cancer growth by regulating activity and expression of the Sox2 transcription factor

Ali J. Calderon-Aparicio, Hiroyuki Yamamoto, Humberto de vitto, Tianshun Zhang, Qiushi Wang, Ann M. Bode, Zigang Dong

Cancer Res (2020) 80 (16_Supplement): 2469.

DOI: https://doi.org/10.1158/1538-7445.AM2020-2469

Published: 15 August 2020

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Journal Articles

Abstract 2593: Inhibition of COX1/2-driven thromboxane A2 pathway suppresses Barrett's esophagus and esophageal adenocarcinoma development

Tianshun Zhang, Qiushi Wang, Wei-Ya Ma, Keke Wang, Xiaoyu Chang, Michele L. Johnson, Ruihua Bai, Ann M. Bode, Nathan R. Foster, Gary W. Falk, Prasad G. Iyer, Zigang Dong

Cancer Res (2020) 80 (16_Supplement): 2593.

DOI: https://doi.org/10.1158/1538-7445.AM2020-2593

Published: 15 August 2020

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Journal Articles

Abstract 1113: Targeting PRPK function blocks colon cancer metastasis

Tatyana Zykova, Ke Yao, Seung Ho Shin, Eunmiri Roh, Weiya Ma, Ann M. Bode, Zigang Dong

Cancer Res (2019) 79 (13_Supplement): 1113.

DOI: https://doi.org/10.1158/1538-7445.AM2019-1113

Published: 01 July 2019

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Journal Articles

Abstract 1770: RSK2 is required for TRAF6 phosphorylation-mediated colon inflammation

Ke Yao, Sung-Young Lee, Cong Peng, Do Young Lim, Hiroyuki Yamamoto, Joohyun Ryu, Tae-Gyu Lim, Hanyong Chen, Wei-Ya Ma, Ann M. Bode, Zigang Dong

Cancer Res (2019) 79 (13_Supplement): 1770.

DOI: https://doi.org/10.1158/1538-7445.AM2019-1770

Published: 01 July 2019

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Journal Articles

Abstract 2959: Deoxysappanchalcone inhibits cell growth by regulation of TOPK signaling pathway in colon cancer

Ran Zhao, Hai Huang, Bu Young Choi, Mengqiu Song, Fanxiang Yin, Xiaorong Fu, Hanyong Chen, Jung Hyun Shim, Mee-Hyun Lee, Zigang Dong

Cancer Res (2019) 79 (13_Supplement): 2959.

DOI: https://doi.org/10.1158/1538-7445.AM2019-2959

Published: 01 July 2019

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Journal Articles

Abstract 1718: Down-regulation of p16^INK4a by hYSK1 promotes cancer cell migration under hypoxic conditions

Mee-Hyun Lee, Jung-Hyun Shim, Zigang Dong, Young-Joon Surh, Bu Young Choi

Cancer Res (2019) 79 (13_Supplement): 1718.

DOI: https://doi.org/10.1158/1538-7445.AM2019-1718

Published: 01 July 2019

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Journal Articles

Abstract 4656: TRAF1 is critical for regulating the BRAF/MEK/ERK pathway in non-small cell lung carcinogenesis

Qiushi Wang, Tianshun Zhang, Ge Gao, Ann Bode, Zigang Dong

Cancer Res (2019) 79 (13_Supplement): 4656.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4656

Published: 01 July 2019

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Journal Articles

Abstract 4798: The Ashitaba (Angelica keiskei) chalcones 4-hydroxyderricin and xanthoangelol suppress melanomagenesis by targeting BRAF and PI3-K

Tianshun Zhang, Qiushi Wang, Hitoshi Ashida, Ann Bode, Zigang Dong

Cancer Res (2019) 79 (13_Supplement): 4798.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4798

Published: 01 July 2019

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Journal Articles

Abstract 5293: Celf2 suppresses non-small cell lung carcinoma growth by inhibiting the prex2-pten interaction

Yiu To Yeung, Suyu Fan, Bingbing Lu, Xiang Li, Ann M. Bode, Zigang Dong

Cancer Res (2019) 79 (13_Supplement): 5293.

DOI: https://doi.org/10.1158/1538-7445.AM2019-5293

Published: 01 July 2019

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Journal Articles

Abstract 4299: Targeting AKT with oridonin inhibits growth of esophageal squamous cell carcinoma in vitro and patient-derived xenografts in vivo

Mengqiu Song, Ran Zhao, Hua Xie, Hanyong Chen, Kangdong Liu, Ann M. Bode, Mee-Hyun Lee, Zigang Dong

Cancer Res (2019) 79 (13_Supplement): 4299.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4299

Published: 01 July 2019

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Journal Articles

Abstract 4391: Disruption of the translation initiation complex by eIF4A mutant inhibits prostate tumor growth in vivo

Puja Singh, Hanyong Chen, Hanxuan Li, Young-In Chi, Bin Liu, Junxuan Lu, Wei Li, Zigang Dong, Yibin Deng

Cancer Res (2019) 79 (13_Supplement): 4391.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4391

Published: 01 July 2019

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Journal Articles

AKT as a Therapeutic Target for Cancer

Mengqiu Song, Ann M. Bode, Zigang Dong, Mee-Hyun Lee

Cancer Res (2019) 79 (6): 1019–1031.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-2738

Published: 15 March 2019

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NARROW

Cancer Etiology and Prevention Principle: “1 + X”

GSK3β-Mediated Expression of CUG-Translated WT1 Is Critical for Tumor Progression

Targeting CDK12 for Cancer Therapy: Function, Mechanism, and Drug Discovery

ARC Is a Critical Protector against Inflammatory Bowel Disease (IBD) and IBD-Associated Colorectal Tumorigenesis

Abstract 422: IL-10 inhibition accelerates gastric tumorigenesis in mice with either Helicobacter pylori infection or chronic alcohol intake

Abstract 5810: Fyn kinase negatively regulates telomere length in stem cells and cancer cells

Abstract 6380: Suppression of the solar ultraviolet-induced skin carcinogenesis by TOPK inhibitor HI-TOPK-032

Abstract 1443: Inhibiting HMG-CoA reductase suppresses non-small cell lung carcinogenesis

Abstract 2469: RCC2 promotes esophageal cancer growth by regulating activity and expression of the Sox2 transcription factor

Abstract 2593: Inhibition of COX1/2-driven thromboxane A2 pathway suppresses Barrett's esophagus and esophageal adenocarcinoma development

Abstract 1113: Targeting PRPK function blocks colon cancer metastasis

Abstract 1770: RSK2 is required for TRAF6 phosphorylation-mediated colon inflammation

Abstract 2959: Deoxysappanchalcone inhibits cell growth by regulation of TOPK signaling pathway in colon cancer

Abstract 1718: Down-regulation of p16^INK4a by hYSK1 promotes cancer cell migration under hypoxic conditions

Abstract 4656: TRAF1 is critical for regulating the BRAF/MEK/ERK pathway in non-small cell lung carcinogenesis

Abstract 4798: The Ashitaba (Angelica keiskei) chalcones 4-hydroxyderricin and xanthoangelol suppress melanomagenesis by targeting BRAF and PI3-K

Abstract 5293: Celf2 suppresses non-small cell lung carcinoma growth by inhibiting the prex2-pten interaction

Abstract 4299: Targeting AKT with oridonin inhibits growth of esophageal squamous cell carcinoma in vitro and patient-derived xenografts in vivo

Abstract 4391: Disruption of the translation initiation complex by eIF4A mutant inhibits prostate tumor growth in vivo

AKT as a Therapeutic Target for Cancer

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