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Journal Articles

Targeting Galectin-1 Overcomes Paclitaxel Resistance in Esophageal Squamous Cell Carcinoma

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Liting Zhou, Jie Tian, Keke Wang, Yijie Ma, Xiaojie Chen, Hui Luo, Bingbing Lu, Nan Wang, Penglei Wang, Xuejiao Liu, Ran Zhao, Simin Zhao, Jiutao Wang, Wenna Nie, Hong Ge, Wenting Liu, Tingxuan Gu, Kangdong Liu, Mee-Hyun Lee, Xiang Li, Zigang Dong
Journal: Cancer Research
Cancer Res (2024) 84 (22): 3894–3908.
https://doi.org/10.1158/0008-5472.CAN-23-2241
Published: 15 November 2024
View articletitled, Targeting Galectin-1 Overcomes Paclitaxel Resistance in Esophageal Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Cancer Etiology and Prevention Principle: “1 + X”

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Hui Liu, Zigang Dong
Journal: Cancer Research
Cancer Res (2021) 81 (21): 5377–5395.
https://doi.org/10.1158/0008-5472.CAN-21-1862
Published: 01 November 2021
View articletitled, Cancer Etiology and Prevention Principle: “1 + X”
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Includes: Supplementary data
Journal Articles

GSK3β-Mediated Expression of CUG-Translated WT1 Is Critical for Tumor Progression

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Hisae Yoshitomi, Kun Y. Lee, Ke Yao, Seung Ho Shin, Tianshun Zhang, Qiushi Wang, Souren Paul, Eunmiri Roh, Joohyun Ryu, Hanyong Chen, Faisal Aziz, Abhijit Chakraborty, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2021) 81 (4): 945–955.
https://doi.org/10.1158/0008-5472.CAN-20-1880
Published: 15 February 2021
View articletitled, GSK3β-Mediated Expression of CUG-Translated WT1 Is Critical for Tumor Progression
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Includes: Supplementary data
Journal Articles

Targeting CDK12 for Cancer Therapy: Function, Mechanism, and Drug Discovery

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Hui Liu, Kangdong Liu, Zigang Dong
Journal: Cancer Research
Cancer Res (2021) 81 (1): 18–26.
https://doi.org/10.1158/0008-5472.CAN-20-2245
Published: 04 January 2021
View articletitled, Targeting CDK12 for Cancer Therapy: Function, Mechanism, and Drug Discovery
Open the PDF for Targeting CDK12 for Cancer Therapy: Function, Mechanism, and Drug Discovery in another window
Includes: Supplementary data
Journal Articles

ARC Is a Critical Protector against Inflammatory Bowel Disease (IBD) and IBD-Associated Colorectal Tumorigenesis

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Qiushi Wang, Tianshun Zhang, Xiaoyu Chang, Do Young Lim, Keke Wang, Ruihua Bai, Ting Wang, Joohyun Ryu, Hanyong Chen, Ke Yao, Wei-Ya Ma, Lisa A. Boardman, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2020) 80 (19): 4158–4171.
https://doi.org/10.1158/0008-5472.CAN-20-0469
Published: 02 October 2020
View articletitled, ARC Is a Critical Protector against Inflammatory Bowel Disease (IBD) and IBD-Associated Colorectal Tumorigenesis
Open the PDF for ARC Is a Critical Protector against Inflammatory Bowel Disease (IBD) and IBD-Associated Colorectal Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

Abstract 1443: Inhibiting HMG-CoA reductase suppresses non-small cell lung carcinogenesis

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Qiushi Wang, Tianshun Zhang, Ruihua Bai, Keke Wang, Xiang Li, Kangdong Liu, Ting Wang, Xiaoyu Chang, Weiya Ma, Ann Bode, Qingxin Xia, Yongping Song, Zigang Dong
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1443.
https://doi.org/10.1158/1538-7445.AM2020-1443
Published: 15 August 2020
View articletitled, Abstract 1443: Inhibiting HMG-CoA reductase suppresses non-small cell lung carcinogenesis
Journal Articles

Abstract 422: IL-10 inhibition accelerates gastric tumorigenesis in mice with either Helicobacter pylori infection or chronic alcohol intake

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Faisal aziz, Ann Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 422.
https://doi.org/10.1158/1538-7445.AM2020-422
Published: 15 August 2020
View articletitled, Abstract 422: IL-10 inhibition accelerates gastric tumorigenesis in mice with either Helicobacter pylori infection or chronic alcohol intake
Journal Articles

Abstract 5810: Fyn kinase negatively regulates telomere length in stem cells and cancer cells

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Souren Paul, Thi My Le Le, Joohyun Ryu, Ki Beom Bae, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5810.
https://doi.org/10.1158/1538-7445.AM2020-5810
Published: 15 August 2020
View articletitled, Abstract 5810: Fyn kinase negatively regulates telomere length in stem cells and cancer cells
Journal Articles

Abstract 6380: Suppression of the solar ultraviolet-induced skin carcinogenesis by TOPK inhibitor HI-TOPK-032

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Eunmiri Roh, Yaping Han, Kanamata Reddy, Tatyana A. Zykova, Mee Hyun Lee, Ke Yao, Ruihua Bai, Clara Curiel-Lewandrowski, Zigang Dong
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6380.
https://doi.org/10.1158/1538-7445.AM2020-6380
Published: 15 August 2020
View articletitled, Abstract 6380: Suppression of the solar ultraviolet-induced skin carcinogenesis by TOPK inhibitor HI-TOPK-032
Journal Articles

Abstract 2469: RCC2 promotes esophageal cancer growth by regulating activity and expression of the Sox2 transcription factor

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Ali J. Calderon-Aparicio, Hiroyuki Yamamoto, Humberto de vitto, Tianshun Zhang, Qiushi Wang, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2469.
https://doi.org/10.1158/1538-7445.AM2020-2469
Published: 15 August 2020
View articletitled, Abstract 2469: RCC2 promotes esophageal cancer growth by regulating activity and expression of the Sox2 transcription factor
Journal Articles

Abstract 2593: Inhibition of COX1/2-driven thromboxane A2 pathway suppresses Barrett's esophagus and esophageal adenocarcinoma development

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Tianshun Zhang, Qiushi Wang, Wei-Ya Ma, Keke Wang, Xiaoyu Chang, Michele L. Johnson, Ruihua Bai, Ann M. Bode, Nathan R. Foster, Gary W. Falk, Prasad G. Iyer, Zigang Dong
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2593.
https://doi.org/10.1158/1538-7445.AM2020-2593
Published: 15 August 2020
View articletitled, Abstract 2593: Inhibition of COX1/2-driven thromboxane A2 pathway suppresses Barrett's esophagus and esophageal adenocarcinoma development
Journal Articles

Abstract 1770: RSK2 is required for TRAF6 phosphorylation-mediated colon inflammation

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Ke Yao, Sung-Young Lee, Cong Peng, Do Young Lim, Hiroyuki Yamamoto, Joohyun Ryu, Tae-Gyu Lim, Hanyong Chen, Wei-Ya Ma, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1770.
https://doi.org/10.1158/1538-7445.AM2019-1770
Published: 01 July 2019
View articletitled, Abstract 1770: RSK2 is required for TRAF6 phosphorylation-mediated colon inflammation
Journal Articles

Abstract 1113: Targeting PRPK function blocks colon cancer metastasis

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Tatyana Zykova, Ke Yao, Seung Ho Shin, Eunmiri Roh, Weiya Ma, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1113.
https://doi.org/10.1158/1538-7445.AM2019-1113
Published: 01 July 2019
View articletitled, Abstract 1113: Targeting PRPK function blocks colon cancer metastasis
Journal Articles

Abstract 4656: TRAF1 is critical for regulating the BRAF/MEK/ERK pathway in non-small cell lung carcinogenesis

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Qiushi Wang, Tianshun Zhang, Ge Gao, Ann Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4656.
https://doi.org/10.1158/1538-7445.AM2019-4656
Published: 01 July 2019
View articletitled, Abstract 4656: TRAF1 is critical for regulating the BRAF/MEK/ERK pathway in non-small cell lung carcinogenesis
Journal Articles

Abstract 4798: The Ashitaba (Angelica keiskei) chalcones 4-hydroxyderricin and xanthoangelol suppress melanomagenesis by targeting BRAF and PI3-K

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Tianshun Zhang, Qiushi Wang, Hitoshi Ashida, Ann Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4798.
https://doi.org/10.1158/1538-7445.AM2019-4798
Published: 01 July 2019
View articletitled, Abstract 4798: The Ashitaba (Angelica keiskei) chalcones 4-hydroxyderricin and xanthoangelol suppress melanomagenesis by targeting BRAF and PI3-K
Journal Articles

Abstract 2959: Deoxysappanchalcone inhibits cell growth by regulation of TOPK signaling pathway in colon cancer

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Ran Zhao, Hai Huang, Bu Young Choi, Mengqiu Song, Fanxiang Yin, Xiaorong Fu, Hanyong Chen, Jung Hyun Shim, Mee-Hyun Lee, Zigang Dong
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2959.
https://doi.org/10.1158/1538-7445.AM2019-2959
Published: 01 July 2019
View articletitled, Abstract 2959: Deoxysappanchalcone inhibits cell growth by regulation of TOPK signaling pathway in colon cancer
Journal Articles

Abstract 5293: Celf2 suppresses non-small cell lung carcinoma growth by inhibiting the prex2-pten interaction

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Yiu To Yeung, Suyu Fan, Bingbing Lu, Xiang Li, Ann M. Bode, Zigang Dong
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5293.
https://doi.org/10.1158/1538-7445.AM2019-5293
Published: 01 July 2019
View articletitled, Abstract 5293: Celf2 suppresses non-small cell lung carcinoma growth by inhibiting the prex2-pten interaction
Journal Articles

Abstract 1718: Down-regulation of p16INK4a by hYSK1 promotes cancer cell migration under hypoxic conditions

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Mee-Hyun Lee, Jung-Hyun Shim, Zigang Dong, Young-Joon Surh, Bu Young Choi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1718.
https://doi.org/10.1158/1538-7445.AM2019-1718
Published: 01 July 2019
View articletitled, Abstract 1718: Down-regulation of p16INK4a by hYSK1 promotes cancer cell migration under hypoxic conditions
Journal Articles

Abstract 4299: Targeting AKT with oridonin inhibits growth of esophageal squamous cell carcinoma in vitro and patient-derived xenografts in vivo

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Mengqiu Song, Ran Zhao, Hua Xie, Hanyong Chen, Kangdong Liu, Ann M. Bode, Mee-Hyun Lee, Zigang Dong
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4299.
https://doi.org/10.1158/1538-7445.AM2019-4299
Published: 01 July 2019
View articletitled, Abstract 4299: Targeting AKT with oridonin inhibits growth of esophageal squamous cell carcinoma in vitro and patient-derived xenografts in vivo
Journal Articles

Abstract 4391: Disruption of the translation initiation complex by eIF4A mutant inhibits prostate tumor growth in vivo

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Puja Singh, Hanyong Chen, Hanxuan Li, Young-In Chi, Bin Liu, Junxuan Lu, Wei Li, Zigang Dong, Yibin Deng
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4391.
https://doi.org/10.1158/1538-7445.AM2019-4391
Published: 01 July 2019
View articletitled, Abstract 4391: Disruption of the translation initiation complex by eIF4A mutant inhibits prostate tumor growth in vivo