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Journal Articles

The Proteomic Landscape of Growth Factor Signaling Networks Associated with FAT1 Mutations in Head and Neck Cancers

Zhengjia Chen, Chao Zhang, Jianhong Chen, Dongsheng Wang, Jieqi Tu, Carter Van Waes, Nabil F. Saba, Zhuo G. Chen, Zhong Chen

Cancer Res (2021) 81 (17): 4402–4416.

https://doi.org/10.1158/0008-5472.CAN-20-3659

Published: 01 September 2021

View articletitled, The Proteomic Landscape of Growth Factor Signaling Networks Associated with FAT1 Mutations in Head and Neck Cancers

Includes: Supplementary data

Journal Articles

Abstract 1907: Src-Met signaling confers apoptosis resistance to EGFR and PI3K co-targeting independently of AKT and ERK pathway activation in head and neck cancer

Abu S. Anisuzzaman, Abedul Haque, Zhuo G. Chen, Dong M. Shin, A.R.M. Ruhul Amin

Cancer Res (2020) 80 (16_Supplement): 1907.

https://doi.org/10.1158/1538-7445.AM2020-1907

Published: 15 August 2020

View articletitled, Abstract 1907: Src-Met signaling confers apoptosis resistance to EGFR and PI3K co-targeting independently of AKT and ERK pathway activation in head and neck cancer

Journal Articles

mTORC2 Suppresses GSK3-Dependent Snail Degradation to Positively Regulate Cancer Cell Invasion and Metastasis

Shuo Zhang, Guoqing Qian, Qian-Qian Zhang, Yuying Yao, Dongsheng Wang, Zhuo G. Chen, Li-Jing Wang, Mingwei Chen, Shi-Yong Sun

Cancer Res (2019) 79 (14): 3725–3736.

https://doi.org/10.1158/0008-5472.CAN-19-0180

Published: 15 July 2019

View articletitled, mTORC2 Suppresses GSK3-Dependent Snail Degradation to Positively Regulate Cancer Cell Invasion and Metastasis

Includes: Supplementary data

Journal Articles

Abstract 4598: mTORC2 suppresses GSK3-dependent, but b-TrCP-independent, Snail degradation, contributing to positive regulation of cancer cell invasion and metastasis

Shuo Zhang, Guoqing Qian, Qian-Qian Zhang, Yuying Yao, DongSheng Wang, Zhuo G. Chen, Lijing Wang, Mingwei Chen, Shi-Yong Sun

Cancer Res (2019) 79 (13_Supplement): 4598.

https://doi.org/10.1158/1538-7445.AM2019-4598

Published: 01 July 2019

View articletitled, Abstract 4598: mTORC2 suppresses GSK3-dependent, but b-TrCP-independent, Snail degradation, contributing to positive regulation of cancer cell invasion and metastasis

Journal Articles

Abstract 3701: Targeted Bcl2 siRNA delivery using DNA nanoparticles in cancer therapy

Mohammad Aminur Rahman, Pengfei Wang, Dongsheng Wang, Sreenivas Nannapaneni, Selwyn J. Hurwitz, Zhuo G. Chen, Yonggang Ke, Dong M. Shin

Cancer Res (2018) 78 (13_Supplement): 3701.

https://doi.org/10.1158/1538-7445.AM2018-3701

Published: 01 July 2018

View articletitled, Abstract 3701: Targeted Bcl2 siRNA delivery using DNA nanoparticles in cancer therapy

Journal Articles

Abstract 187: Efficient delivery of Bcl2 siRNA by DNA nanoparticles to inhibit cellular growth and cancer progression

Mohammad Aminur Rahman, Pengfei Wang, Dongsheng Wang, Selwyn J. Hurwitz, Zhengjia Chen, Zhuo G. Chen, Yonggang Ke, Dong M. Shin

Cancer Res (2017) 77 (13_Supplement): 187.

https://doi.org/10.1158/1538-7445.AM2017-187

Published: 01 July 2017

View articletitled, Abstract 187: Efficient delivery of Bcl2 siRNA by DNA nanoparticles to inhibit cellular growth and cancer progression

Journal Articles

Abstract 4110: Combinatory approaches targeting EGFR, HER2 and c-MET in recurrent SCCHN

Dongsheng Wang, Kelly R. Magliocca, Sreenivas Nannapaneni, Coner Steuer, Mihir R. Patel, Mark W. El-Deiry, Xu Wang, Zhengjia Chen, Dong M. Shin, Nabil F. Saba, Zhuo G. Chen

Cancer Res (2017) 77 (13_Supplement): 4110.

https://doi.org/10.1158/1538-7445.AM2017-4110

Published: 01 July 2017

View articletitled, Abstract 4110: Combinatory approaches targeting EGFR, HER2 and c-MET in recurrent SCCHN

Journal Articles

Modulation of Bax and mTOR for Cancer Therapeutics

Cancer Res (2017) 77 (11): 3001–3012.

https://doi.org/10.1158/0008-5472.CAN-16-2356

Published: 31 May 2017

View articletitled, Modulation of Bax and mTOR for Cancer Therapeutics

Includes: Supplementary data

Journal Articles

Abstract 515: Survivin contributes to radiation resistance in head and neck cancer through regulation of DNA damage repair

Xu Wang, Jonathan J. Beitler, Wen Huang, Guo Chen, Sreenivas Nannapaneni, Nabil F. Saba, Xingming Deng, Zhuo G. Chen, Dong M. Shin

Cancer Res (2016) 76 (14_Supplement): 515.

https://doi.org/10.1158/1538-7445.AM2016-515

Published: 15 July 2016

View articletitled, Abstract 515: Survivin contributes to radiation resistance in head and neck cancer through regulation of DNA damage repair

Journal Articles

Abstract 1866: HER3 targeting sensitizes HNSCC to cetuximab - evidence from cell line and patient derived xenograft (PDX) models

Dongsheng Wang, Guoqing Qian, hongzheng zhang, kelly R. Magliocca, sreenivas nannapaneni, zhengjia chen, mihir R. patel, Mark W. El-Deiry, J.trad Wadsworth, dong M. Shin, fadlo R. khuri, Nabil F. Saba, Zhuo G. chen

Cancer Res (2016) 76 (14_Supplement): 1866.

https://doi.org/10.1158/1538-7445.AM2016-1866

Published: 15 July 2016

View articletitled, Abstract 1866: HER3 targeting sensitizes HNSCC to cetuximab - evidence from cell line and patient derived xenograft (PDX) models

Journal Articles

Abstract B15: RSK2 signals through stathmin to promote microtubule dynamics and tumor metastasis

Gina Alesi, Lingtao Jin, Dan Li, Kelly Magliocca, Yibin Kang, Zhuo G. Chen, Dong M. Shin, Fadlo R. Khuri, Sumin Kang

Cancer Res (2016) 76 (7_Supplement): B15.

https://doi.org/10.1158/1538-7445.TUMMET15-B15

Published: 26 May 2016

View articletitled, Abstract B15: RSK2 signals through stathmin to promote microtubule dynamics and tumor metastasis

Journal Articles

Abstract 20: Honokiol radiosensitizes squamous cells carcinoma of head and neck by down-regulation of survivin

Xu Wang, Jonathan J. Beitler, Wen Huang, Guoqing Qian, Kelly Magliocca, Jun Zhang, Sreenivas Nannapaneni, Sungjin Kim, Zhengjia Chen, Saba F. Nabil, Zhuo G. Chen, Jack L. Arbiser, Dong M. Shin

Cancer Res (2015) 75 (15_Supplement): 20.

https://doi.org/10.1158/1538-7445.AM2015-20

Published: 01 August 2015

View articletitled, Abstract 20: Honokiol radiosensitizes squamous cells carcinoma of head and neck by down-regulation of survivin

Journal Articles

Abstract 813: Human papillomavirus 16 oncoprotein E6 upregulates c-Met partially through p53 in squamous cell carcinoma of the head and neck

Guoqing Qian, Dongsheng Wang, Kelly R. Magliocca, Praveen Duggal, Sreenivas Nannapaneni, Sungjin Kim, Zhengjia Chen, Dong M. Shin, Nabil F. Saba, Zhuo G. Chen

Cancer Res (2015) 75 (15_Supplement): 813.

https://doi.org/10.1158/1538-7445.AM2015-813

Published: 01 August 2015

View articletitled, Abstract 813: Human papillomavirus 16 oncoprotein E6 upregulates c-Met partially through p53 in squamous cell carcinoma of the head and neck

Journal Articles

Abstract 29: Potent curcumin analog FLLL12 induces apoptosis in lung cancer cells through death receptor-5-dependent pathway

Abedul Haque, Mohammad A. Rahman, James R. Fuchs, Zhuo G. Chen, Fadlo R. Khuri, Dong M. Shin, A.R.M. Ruhul Amin

Cancer Res (2015) 75 (15_Supplement): 29.

https://doi.org/10.1158/1538-7445.AM2015-29

Published: 01 August 2015

View articletitled, Abstract 29: Potent curcumin analog FLLL12 induces apoptosis in lung cancer cells through death receptor-5-dependent pathway

Journal Articles

Abstract 2283: Potent curcumin analog FLLL-12 targets both intrinsic and extrinsic signaling pathways to induce apoptosis in lung cancers

A.R.M. Ruhul Amin, Abedul Haque, Mohammad A. Rahman, James R. Fuchs, Zhuo G. Chen, Dong M. Shin

Cancer Res (2014) 74 (19_Supplement): 2283.

https://doi.org/10.1158/1538-7445.AM2014-2283

Published: 01 October 2014

View articletitled, Abstract 2283: Potent curcumin analog FLLL-12 targets both intrinsic and extrinsic signaling pathways to induce apoptosis in lung cancers

Journal Articles

Abstract 2269: Combination of erlotinib and epigallocatechin-3-gallate induces apoptosis of squamous cell carcinoma of the head and neck through posttranslational regulation of Bim and Bcl-2

Abedul Haque, Mohammad A. Rahman, Zhuo G. Chen, Dong M. Shin, A.R.M. Ruhul Amin

Cancer Res (2014) 74 (19_Supplement): 2269.

https://doi.org/10.1158/1538-7445.AM2014-2269

Published: 01 October 2014

View articletitled, Abstract 2269: Combination of erlotinib and epigallocatechin-3-gallate induces apoptosis of squamous cell carcinoma of the head and neck through posttranslational regulation of Bim and Bcl-2

Journal Articles

Abstract 3763: Ribonucleotide reductase subunit M2 plays important role in cisplatin resistance of cancer cells

Mohammad Aminur Rahman, A.R.M. R. Amin, Xianghong Peng, Jun Zhang, Zhuo G. Chen, Dong M. Shin

Cancer Res (2014) 74 (19_Supplement): 3763.

https://doi.org/10.1158/1538-7445.AM2014-3763

Published: 01 October 2014

View articletitled, Abstract 3763: Ribonucleotide reductase subunit M2 plays important role in cisplatin resistance of cancer cells

Journal Articles

Abstract 2925: p90RSK2 coordinates pro-apoptotic and anti-apoptotic signaling pathways to protect cancer cells from anoikis.

Lingtao Jin, Dan Li, Jongseok Lee, Gina N. Alesi, Jun Fan, Hee-Bum Kang, Dongsheng Wang, Haian Fu, Jack Taunton, Titus J. Boggon, Meghan Tucker, Ting-Lei Gu, Zhuo G. Chen, Dong M. Shin, Fadlo R. Khuri, Sumin Kang

Cancer Res (2013) 73 (8_Supplement): 2925.

https://doi.org/10.1158/1538-7445.AM2013-2925

Published: 15 April 2013

View articletitled, Abstract 2925: p90RSK2 coordinates pro-apoptotic and anti-apoptotic signaling pathways to protect cancer cells from anoikis.

Journal Articles

Abstract 3189: Potent curcumin analogue FLLL-12 targets protein translational pathways to inhibit EGFR, AKT and Bcl-2: potential role in apoptosis induction.

A.R.M. Ruhul Amin, Mohammad A. Rahman, Dongsheng Wang, Fadlo R. Khuri, James R. Fuchs, Zhuo G. Chen, Dong M. Shin

Cancer Res (2013) 73 (8_Supplement): 3189.

https://doi.org/10.1158/1538-7445.AM2013-3189

Published: 15 April 2013

View articletitled, Abstract 3189: Potent curcumin analogue FLLL-12 targets protein translational pathways to inhibit EGFR, AKT and Bcl-2: potential role in apoptosis induction.

Journal Articles

Abstract 1588: Synergistic apoptosis by combination of natural compound EGCG and resveratrol in head and neck cancer: Potential role for AKT-dependent signaling

A.R.M. Ruhul Amin, Mohammad Aminur Rahman, Dongsheng Wang, Fadlo R. Khuri, Zhuo G. Chen, Dong M. Shin

Cancer Res (2012) 72 (8_Supplement): 1588.

https://doi.org/10.1158/1538-7445.AM2012-1588

Published: 15 April 2012

View articletitled, Abstract 1588: Synergistic apoptosis by combination of natural compound EGCG and resveratrol in head and neck cancer: Potential role for AKT-dependent signaling

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The Proteomic Landscape of Growth Factor Signaling Networks Associated with FAT1 Mutations in Head and Neck Cancers

Abstract 1907: Src-Met signaling confers apoptosis resistance to EGFR and PI3K co-targeting independently of AKT and ERK pathway activation in head and neck cancer

mTORC2 Suppresses GSK3-Dependent Snail Degradation to Positively Regulate Cancer Cell Invasion and Metastasis

Abstract 4598: mTORC2 suppresses GSK3-dependent, but b-TrCP-independent, Snail degradation, contributing to positive regulation of cancer cell invasion and metastasis

Abstract 3701: Targeted Bcl2 siRNA delivery using DNA nanoparticles in cancer therapy

Abstract 187: Efficient delivery of Bcl2 siRNA by DNA nanoparticles to inhibit cellular growth and cancer progression

Abstract 4110: Combinatory approaches targeting EGFR, HER2 and c-MET in recurrent SCCHN

Modulation of Bax and mTOR for Cancer Therapeutics

Abstract 515: Survivin contributes to radiation resistance in head and neck cancer through regulation of DNA damage repair

Abstract 1866: HER3 targeting sensitizes HNSCC to cetuximab - evidence from cell line and patient derived xenograft (PDX) models

Abstract B15: RSK2 signals through stathmin to promote microtubule dynamics and tumor metastasis

Abstract 20: Honokiol radiosensitizes squamous cells carcinoma of head and neck by down-regulation of survivin

Abstract 813: Human papillomavirus 16 oncoprotein E6 upregulates c-Met partially through p53 in squamous cell carcinoma of the head and neck

Abstract 29: Potent curcumin analog FLLL12 induces apoptosis in lung cancer cells through death receptor-5-dependent pathway

Abstract 2283: Potent curcumin analog FLLL-12 targets both intrinsic and extrinsic signaling pathways to induce apoptosis in lung cancers

Abstract 2269: Combination of erlotinib and epigallocatechin-3-gallate induces apoptosis of squamous cell carcinoma of the head and neck through posttranslational regulation of Bim and Bcl-2

Abstract 3763: Ribonucleotide reductase subunit M2 plays important role in cisplatin resistance of cancer cells

Abstract 2925: p90RSK2 coordinates pro-apoptotic and anti-apoptotic signaling pathways to protect cancer cells from anoikis.

Abstract 3189: Potent curcumin analogue FLLL-12 targets protein translational pathways to inhibit EGFR, AKT and Bcl-2: potential role in apoptosis induction.

Abstract 1588: Synergistic apoptosis by combination of natural compound EGCG and resveratrol in head and neck cancer: Potential role for AKT-dependent signaling

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