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Journal Articles

Abstract LB364: Generation and Application of a Robust Humanized Mouse Tumor Model System for Evaluation of NK-Targeting Therapeutics

Feng Lu, Weiqun Ding, Guangliang Yang, Yaoqing Jia, Zhaoxiang Wang, Xusheng Yuan, Ming Yin, Zhijian Yang, WenQing Yang

Cancer Res (2024) 84 (7_Supplement): LB364.

https://doi.org/10.1158/1538-7445.AM2024-LB364

Published: 05 April 2024

View article titled, Abstract LB364: Generation and Application of a Robust Humanized Mouse Tumor Model System for Evaluation of NK-Targeting Therapeutics

Journal Articles

Abstract LB362: Systematic development and characterization of orthotopic animal tumor models: A proactive approach to mimic patients' tumor microenvironments for drug discovery

WenQing Yang, Xusheng Yuan, Guangliang Yang, Xiaojun Tong, Weiqun Ding, Qiuxia Zhang, Feng Lu, Zhijian Yang

Cancer Res (2024) 84 (7_Supplement): LB362.

https://doi.org/10.1158/1538-7445.AM2024-LB362

Published: 05 April 2024

View article titled, Abstract LB362: Systematic development and characterization of orthotopic animal tumor models: A proactive approach to mimic patients' tumor microenvironments for drug discovery

Journal Articles

Prolonged survival and lacking response to gemcitabine in athymic but not in SCID-beige mice bearing orthotopically transplanted H69AR lung tumors

Christof Granzow, Xiao-Ming Li, Huaiyu Ma, Zhijian Yang, Robert Hoffman, Marijana Kopun

Cancer Res (2008) 68 (9_Supplement): 2069.

Published: 01 May 2008

View article titled, Prolonged survival and lacking response to gemcitabine in athymic but not in SCID-beige mice bearing orthotopically transplanted H69AR lung tumors

Journal Articles

The role of RANK-signaling in breast cancer development and metastasis

Wei Tan, Weizhou Zhang, Li Tang, Zhijian Yang, Jun-Li Luo, Robert Hoffman, Michael Karin

Cancer Res (2008) 68 (9_Supplement): 4200.

Published: 01 May 2008

View article titled, The role of RANK-signaling in breast cancer development and metastasis

Journal Articles

Imaging the differential engraftment of GFP-expressing spleen and bone marrow cells in various organs of chemotherapy-treated recipient mice

Yuji Heike, Zhijian Yang, Huaiyu Ma, Robert Hoffman, Yuriko Morita, Atsuko Soeda, Hiroaki Makiyama, Kensei Tobinai, Yoichi Takaue

Cancer Res (2007) 67 (9_Supplement): 1330.

Published: 01 May 2007

View article titled, Imaging the differential engraftment of GFP-expressing spleen and bone marrow cells in various organs of chemotherapy-treated recipient mice

Journal Articles

Quantitation of PEGylated methioninase protein in blood

Shukuan Li, Zhijian Yang, Huaiyu Ma, Ming Zhao, Xiao-ming Li, Yuying Tan, Shigeo Yagi, Robert Hoffman

Cancer Res (2007) 67 (9_Supplement): 5569.

Published: 01 May 2007

View article titled, Quantitation of PEGylated methioninase protein in blood

Journal Articles

Efficacy of dietary antioxidants combined with a chemotherapeutic agents on human colon cancer in a fluorescent orthotopic mouse model

Huaiyu Ma, Tapas Das, Suzette Pereira, Xiao-Ming Li, Zhijian Yang, Shigeo Yagi, Pradip Mukerji, Robert Hoffman

Cancer Res (2007) 67 (9_Supplement): 623.

Published: 01 May 2007

View article titled, Efficacy of dietary antioxidants combined with a chemotherapeutic agents on human colon cancer in a fluorescent orthotopic mouse model

Journal Articles

Targeted Therapy with a Salmonella Typhimurium Leucine-Arginine Auxotroph Cures Orthotopic Human Breast Tumors in Nude Mice

Ming Zhao, Meng Yang, Huaiyu Ma, Xiaoming Li, Xiuying Tan, Shukuan Li, Zhijian Yang, Robert M. Hoffman

Cancer Res (2006) 66 (15): 7647–7652.

https://doi.org/10.1158/0008-5472.CAN-06-0716

Published: 02 August 2006

View article titled, Targeted Therapy with a Salmonella Typhimurium Leucine-Arginine Auxotroph Cures Orthotopic Human Breast Tumors in Nude Mice

Journal Articles

A novel alkylateing agent, glufosfamide, enhances activity of gemcitabine in models of pancreatic cancer

William S. Ammons, Jin-Wei Wang, Zhijian Yang, Robert M. Hoffman, George F. Tidmarsh, Alan Colowick

Cancer Res (2006) 66 (8_Supplement): 1113.

Published: 15 April 2006

View article titled, A novel alkylateing agent, glufosfamide, enhances activity of gemcitabine in models of pancreatic cancer

Journal Articles

Breast-tumor-targeted therapy with a Salmonella typhimurium LEU-ARG auxotroph

Ming Zhao, Meng Yang, Xiao-Ming Li, Xiuying Tan, Skukuan Li, Huaiyu Ma, Zhijian Yang, Robert M. Hoffman

Cancer Res (2006) 66 (8_Supplement): 513.

Published: 15 April 2006

View article titled, Breast-tumor-targeted therapy with a Salmonella typhimurium LEU-ARG auxotroph

Journal Articles

An effective method to remove endotoxin from PEGylated recombinant methioninase

Shukuan Li, Xinghua Sun, Zhijian Yang, Yuying Tan, Shigeo Yagi, Robert M. Hoffman

Cancer Res (2006) 66 (8_Supplement): 513.

Published: 15 April 2006

View article titled, An effective method to remove endotoxin from PEGylated recombinant methioninase

Journal Articles

The effect of PEGylation on the enzyme kinetics of recombinant methioninase

Shukuan Li, Zhijian Yang, Xinghua Sun, Yuying Tan, Shigeo Yagi, Robert M. Hoffman

Cancer Res (2006) 66 (8_Supplement): 513.

Published: 15 April 2006

View article titled, The effect of PEGylation on the enzyme kinetics of recombinant methioninase

Journal Articles

Role of activation of the Polycomb Group (PcG) protein chromatin silencing pathway in metastatic prostate cancer

Gennadi V. Glinsky, Olga Berezovska, Zhijian Yang, Xiao-Ming Li, Robert M. Hoffman, Anna B. Glinskii

Cancer Res (2006) 66 (8_Supplement): 995.

Published: 15 April 2006

View article titled, Role of activation of the Polycomb Group (PcG) protein chromatin silencing pathway in metastatic prostate cancer

Journal Articles

PEGylation confers greatly extended half-life and attenuated immunogenicity to recombinant methioninase in primates

Zhijian Yang, Junhua Wang, Quan Lu, Jinbao Xu, Yoshinao Kobayashi, Tomoaki Takakura, Akio Takimoto, Takayuki Yoshioka, Changgen Lian, Chunmei Chen, Dongdong Zhang, Ying Zhang, Shukuan Li, Xinghua Sun, Yuying Tan, Shigeo Yagi, Eugene P. Frenkel, Robert M. Hoffman

Cancer Res (2005) 65 (9_Supplement): 329.

Published: 01 May 2005

View article titled, PEGylation confers greatly extended half-life and attenuated immunogenicity to recombinant methioninase in primates

Journal Articles

Imageable intratibial implantation model of GFP-expressing multiple myeloma cells

Meng Yang, Mingxu Xu, Zhijian Yang, Ping Jiang, Constantine Mitsiades, Robert M. Hoffman

Cancer Res (2005) 65 (9_Supplement): 1392.

Published: 01 May 2005

View article titled, Imageable intratibial implantation model of GFP-expressing multiple myeloma cells

Journal Articles

An improved optically imageable metastatic model of human colon cancer orthotopically implanted on the cecum

Huaiyu Ma, Jin Wei Wang, Xiao-Ming Li, Zhijian Yang, Meng Yang, A. R. Moossa, Robert M. Hoffman

Cancer Res (2005) 65 (9_Supplement): 1334.

Published: 01 May 2005

View article titled, An improved optically imageable metastatic model of human colon cancer orthotopically implanted on the cecum

Journal Articles

Targeting of breast cancer with selected amino acid auxotrophic variants of GFP-expressing Salmonella typhimurium

Ming Zhao, Xiao-Ming Li, Meng Yang, Yin Yie, Xuiying Tan, Ping Jiang, Zhijian Yang, Sanford Barsky, Robert M. Hoffman

Cancer Res (2005) 65 (9_Supplement): 1189.

Published: 01 May 2005

View article titled, Targeting of breast cancer with selected amino acid auxotrophic variants of GFP-expressing Salmonella typhimurium

Journal Articles

Sensitive assay of tumor S-adenosyl-methionine and S-adenosyl-homocysteine

Shukuan Li, Zhijian Yang, Xinghua Sun, Xiao-Ming Li, Mingxu Xu, Huaiyu Ma, Yuying Tan, Shigeo Yagi, Robert M. Hoffman

Cancer Res (2005) 65 (9_Supplement): 556.

Published: 01 May 2005

View article titled, Sensitive assay of tumor S-adenosyl-methionine and S-adenosyl-homocysteine

Journal Articles

PEGylation Confers Greatly Extended Half-Life and Attenuated Immunogenicity to Recombinant Methioninase in Primates

Zhijian Yang, Junhua Wang, Quan Lu, Jinbao Xu, Yoshinao Kobayashi, Tomoaki Takakura, Akio Takimoto, Takayuji Yoshioka, Changgen Lian, Chunmei Chen, Dongdong Zhang, Ying Zhang, Shukuan Li, Xinghua Sun, Yuying Tan, Shigeo Yagi, Eugene P. Frenkel, Robert M. Hoffman

Cancer Res (2004) 64 (18): 6673–6678.

https://doi.org/10.1158/0008-5472.CAN-04-1822

Published: 16 September 2004

View article titled, PEGylation Confers Greatly Extended Half-Life and Attenuated Immunogenicity to Recombinant Methioninase in Primates

Journal Articles

Circulating Half-Life of PEGylated Recombinant Methioninase Holoenzyme Is Highly Dose Dependent on Cofactor Pyridoxal-5′-Phosphate

Zhijian Yang, Xinghua Sun, Shukuan Li, Yuying Tan, Xiaoen Wang, Nan Zhang, Shigeo Yagi, Tomoaki Takakura, Yoshinao Kobayashi, Akio Takimoto, Takayuki Yoshioka, Akinori Suginaka, Eugene P. Frenkel, Robert M. Hoffman

Cancer Res (2004) 64 (16): 5775–5778.

https://doi.org/10.1158/0008-5472.CAN-04-1406

Published: 16 August 2004

View article titled, Circulating Half-Life of PEGylated Recombinant Methioninase Holoenzyme Is Highly Dose Dependent on Cofactor Pyridoxal-5′-Phosphate

NARROW

Abstract LB364: Generation and Application of a Robust Humanized Mouse Tumor Model System for Evaluation of NK-Targeting Therapeutics

Abstract LB362: Systematic development and characterization of orthotopic animal tumor models: A proactive approach to mimic patients' tumor microenvironments for drug discovery

Prolonged survival and lacking response to gemcitabine in athymic but not in SCID-beige mice bearing orthotopically transplanted H69AR lung tumors

The role of RANK-signaling in breast cancer development and metastasis

Imaging the differential engraftment of GFP-expressing spleen and bone marrow cells in various organs of chemotherapy-treated recipient mice

Quantitation of PEGylated methioninase protein in blood

Efficacy of dietary antioxidants combined with a chemotherapeutic agents on human colon cancer in a fluorescent orthotopic mouse model

Targeted Therapy with a Salmonella Typhimurium Leucine-Arginine Auxotroph Cures Orthotopic Human Breast Tumors in Nude Mice

A novel alkylateing agent, glufosfamide, enhances activity of gemcitabine in models of pancreatic cancer

Breast-tumor-targeted therapy with a Salmonella typhimurium LEU-ARG auxotroph

An effective method to remove endotoxin from PEGylated recombinant methioninase

The effect of PEGylation on the enzyme kinetics of recombinant methioninase

Role of activation of the Polycomb Group (PcG) protein chromatin silencing pathway in metastatic prostate cancer

PEGylation confers greatly extended half-life and attenuated immunogenicity to recombinant methioninase in primates

Imageable intratibial implantation model of GFP-expressing multiple myeloma cells

An improved optically imageable metastatic model of human colon cancer orthotopically implanted on the cecum

Targeting of breast cancer with selected amino acid auxotrophic variants of GFP-expressing Salmonella typhimurium

Sensitive assay of tumor S-adenosyl-methionine and S-adenosyl-homocysteine

PEGylation Confers Greatly Extended Half-Life and Attenuated Immunogenicity to Recombinant Methioninase in Primates

Circulating Half-Life of PEGylated Recombinant Methioninase Holoenzyme Is Highly Dose Dependent on Cofactor Pyridoxal-5′-Phosphate

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