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Journal Articles

Abstract 4925: Social determinant predictors of lung cancer incidence in diverse urban populations

Free
Vijeth Narra, Alex Krule, Abdul J. Zakkar, Mason Burrage-Burton, Farah Yousef, Vijayakrishna Gadi, Frank Weinberg, Mark Korpics, Yamilé Molina, Sage J. Kim, Margaret Geise-Wright, Zhengjia Chen, Elisabeta Marai, Ryan H. Nguyen, Ameen A. Salahudeen
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4925.
https://doi.org/10.1158/1538-7445.AM2025-4925
Published: 21 April 2025
View articletitled, Abstract 4925: Social determinant predictors of lung cancer incidence in diverse urban populations
Journal Articles

Abstract B037: Expression of MRTFA facilitates an immunosuppressive tumor microenvironment via upregulation of VSIR

Free
Kihak Lee, Stephanie M. Wilk, Alexa M. Gajda, Mohamed Haloul, Virgilia Macias, Elizabeth L. Wiley, Zhengjia Chen, Xinyi Liu, Xiaowei Wang, Maria Sverdlov, Kent F. Hoskins, Ekrem Emrah Er
Journal: Cancer Research
Cancer Res (2024) 84 (22_Supplement): B037.
https://doi.org/10.1158/1538-7445.TUMBODY-B037
Published: 17 November 2024
View articletitled, Abstract B037: Expression of MRTFA facilitates an immunosuppressive tumor microenvironment via upregulation of VSIR
Journal Articles

Abstract PO5-20-04: A Phase II Study of Ribociclib and Endocrine Treatment of Physician’s Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer (RaPhLRR Study)

Free
Oana Danciu, Nancy Chan, Kari Wisinski, Trish Millard, Kathleen Kemmer, Sneha Phadke, Zhengjia Chen, Ana Cuesta Fernandez, Melanie Clark, Alison Conlin, Coral Omene, Sima Ehsani, Stephanie Dublis, Vijayakrishna K. Gadi
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO5-20-04.
https://doi.org/10.1158/1538-7445.SABCS23-PO5-20-04
Published: 02 May 2024
View articletitled, Abstract PO5-20-04: A Phase II Study of Ribociclib and Endocrine Treatment of Physician’s Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer (RaPhLRR Study)
Journal Articles

The Proteomic Landscape of Growth Factor Signaling Networks Associated with FAT1 Mutations in Head and Neck Cancers

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Zhengjia Chen, Chao Zhang, Jianhong Chen, Dongsheng Wang, Jieqi Tu, Carter Van Waes, Nabil F. Saba, Zhuo G. Chen, Zhong Chen
Journal: Cancer Research
Cancer Res (2021) 81 (17): 4402–4416.
https://doi.org/10.1158/0008-5472.CAN-20-3659
Published: 01 September 2021
View articletitled, The Proteomic Landscape of Growth Factor Signaling Networks Associated with FAT1 Mutations in Head and Neck Cancers
Open the PDF for The Proteomic Landscape of Growth Factor Signaling Networks Associated with FAT1 Mutations in Head and Neck Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract 321: Identification of proteins associated with FAT1 mutations which potentially contribute to oncogenesis and progression of head and neck cancers

Free
Zhuo Georgia Chen, Zhengjia Chen, Chao Zhang, Jianhong Chen, Dongsheng Wang, Nabil F. Saba, Zhong Chen
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 321.
https://doi.org/10.1158/1538-7445.AM2021-321
Published: 01 July 2021
View articletitled, Abstract 321: Identification of proteins associated with FAT1 mutations which potentially contribute to oncogenesis and progression of head and neck cancers
Journal Articles

Mcl-1 Interacts with Akt to Promote Lung Cancer Progression

Free
Guo Chen, Dongkyoo Park, Andrew T. Magis, Madhusmita Behera, Suresh S. Ramalingam, Taofeek K. Owonikoko, Gabriel L. Sica, Keqiang Ye, Chao Zhang, Zhengjia Chen, Walter J. Curran, Xingming Deng
Journal: Cancer Research
Cancer Res (2019) 79 (24): 6126–6138.
https://doi.org/10.1158/0008-5472.CAN-19-0950
Published: 13 December 2019
View articletitled, Mcl-1 Interacts with Akt to Promote Lung Cancer Progression
Open the PDF for Mcl-1 Interacts with Akt to Promote Lung Cancer Progression in another window
Includes: Supplementary data
Journal Articles

Abstract 876: Effective reduction of PD-L1 expression by simultaneous blockade of EGFR and HER3 (ErbB3) in head and neck cancer

Free
Zhuo Georgia Chen, Dongsheng Wang, Christopher C. Griffith, Sreenivas Nannapaneni, Conor Steuer, Mihir R. Patel, Mark W. El-Deiry, Xu Wang, Yuzi Zhang, Zhengjia Chen, Diego Alvarado, Dong M. Shin, Nabil F. Saba
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 876.
https://doi.org/10.1158/1538-7445.AM2018-876
Published: 01 July 2018
View articletitled, Abstract 876: Effective reduction of PD-L1 expression by simultaneous blockade of EGFR and HER3 (ErbB3) in head and neck cancer
Journal Articles

Abstract 187: Efficient delivery of Bcl2 siRNA by DNA nanoparticles to inhibit cellular growth and cancer progression

Free
Mohammad Aminur Rahman, Pengfei Wang, Dongsheng Wang, Selwyn J. Hurwitz, Zhengjia Chen, Zhuo G. Chen, Yonggang Ke, Dong M. Shin
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 187.
https://doi.org/10.1158/1538-7445.AM2017-187
Published: 01 July 2017
View articletitled, Abstract 187: Efficient delivery of Bcl2 siRNA by DNA nanoparticles to inhibit cellular growth and cancer progression
Journal Articles

Abstract 4110: Combinatory approaches targeting EGFR, HER2 and c-MET in recurrent SCCHN

Free
Dongsheng Wang, Kelly R. Magliocca, Sreenivas Nannapaneni, Coner Steuer, Mihir R. Patel, Mark W. El-Deiry, Xu Wang, Zhengjia Chen, Dong M. Shin, Nabil F. Saba, Zhuo G. Chen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4110.
https://doi.org/10.1158/1538-7445.AM2017-4110
Published: 01 July 2017
View articletitled, Abstract 4110: Combinatory approaches targeting EGFR, HER2 and c-MET in recurrent SCCHN
Journal Articles

Abstract LB-348: Developing a personalized anti-metastatic therapy to treat KRAS, LKB1-mutant lung adenocarcinoma

Free
Melissa Gilbert-Ross, Jessica Konen, Junghui Koo, John Shupe, Gabriel L. Sica, Zhengjia Chen, Brian S. Robinson, Madhusmita Behera, Michael R. Rossi, Geoffrey H. Smith, Charles E. Hill, Suresh M. Ramalingam, Haian Fu, Fadlo R. Khuri, Wei Zhou, Adam Marcus
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-348.
https://doi.org/10.1158/1538-7445.AM2016-LB-348
Published: 15 July 2016
View articletitled, Abstract LB-348: Developing a personalized anti-metastatic therapy to treat KRAS, LKB1-mutant lung adenocarcinoma
Journal Articles

Abstract 1866: HER3 targeting sensitizes HNSCC to cetuximab - evidence from cell line and patient derived xenograft (PDX) models

Free
Dongsheng Wang, Guoqing Qian, hongzheng zhang, kelly R. Magliocca, sreenivas nannapaneni, zhengjia chen, mihir R. patel, Mark W. El-Deiry, J.trad Wadsworth, dong M. Shin, fadlo R. khuri, Nabil F. Saba, Zhuo G. chen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1866.
https://doi.org/10.1158/1538-7445.AM2016-1866
Published: 15 July 2016
View articletitled, Abstract 1866: HER3 targeting sensitizes HNSCC to cetuximab - evidence from cell line and patient derived xenograft (PDX) models
Journal Articles

Abstract 20: Honokiol radiosensitizes squamous cells carcinoma of head and neck by down-regulation of survivin

Free
Xu Wang, Jonathan J. Beitler, Wen Huang, Guoqing Qian, Kelly Magliocca, Jun Zhang, Sreenivas Nannapaneni, Sungjin Kim, Zhengjia Chen, Saba F. Nabil, Zhuo G. Chen, Jack L. Arbiser, Dong M. Shin
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 20.
https://doi.org/10.1158/1538-7445.AM2015-20
Published: 01 August 2015
View articletitled, Abstract 20: Honokiol radiosensitizes squamous cells carcinoma of head and neck by down-regulation of survivin
Journal Articles

Abstract CT303: A phase I pharmacokinetic and pharmacodynamic evaluation of the combination of everolimus and buparlisib for concurrent mTOR and PI3K pathway blockade in patients with advanced solid tumors

Free
Taofeek Kunle Owonikoko, R.Donald Harvey, Colleen Lewis, Zhengjia Chen, John S. Kauh, Meredith Renfroe, Rijalda Deovic, Gabriel L. Sica, Bradley C. Carthon, Wayne Bernard Harris, Bassel F. El-Rayes, Suresh S. Ramalingam, Fadlo R. Khuri
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): CT303.
https://doi.org/10.1158/1538-7445.AM2015-CT303
Published: 01 August 2015
View articletitled, Abstract CT303: A phase I pharmacokinetic and pharmacodynamic evaluation of the combination of everolimus and buparlisib for concurrent mTOR and PI3K pathway blockade in patients with advanced solid tumors
Journal Articles

Abstract 813: Human papillomavirus 16 oncoprotein E6 upregulates c-Met partially through p53 in squamous cell carcinoma of the head and neck

Free
Guoqing Qian, Dongsheng Wang, Kelly R. Magliocca, Praveen Duggal, Sreenivas Nannapaneni, Sungjin Kim, Zhengjia Chen, Dong M. Shin, Nabil F. Saba, Zhuo G. Chen
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 813.
https://doi.org/10.1158/1538-7445.AM2015-813
Published: 01 August 2015
View articletitled, Abstract 813: Human papillomavirus 16 oncoprotein E6 upregulates c-Met partially through p53 in squamous cell carcinoma of the head and neck
Journal Articles

Abstract 1852: Enhancing specificity in predication of human papillomavirus associated oropharyngeal squamous cell carcinoma by combining biomarkers p16 and β-catenin

Free
Guoqing Qian, Hong Xu, Zhongliang Hu, Sungjin Kim, Dongsheng Wang, Hongzheng Zhang, Zhengjia Chen, Susan Muller, Nabil Saba, Dong M. Shin, Andrew Wang, Zhuo Georgia Chen
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1852.
https://doi.org/10.1158/1538-7445.AM2014-1852
Published: 01 October 2014
View articletitled, Abstract 1852: Enhancing specificity in predication of human papillomavirus associated oropharyngeal squamous cell carcinoma by combining biomarkers p16 and β-catenin
Journal Articles

Abstract 922: Evaluating markers of cisplatin sensitivity and survival in small cell lung cancer

Free
Taofeek Kunle Owonikoko, Guojing Zhang, Gabriel L. Sica, Zhengjia Chen, Jeffrey M. Switchenko, Sungjin Kim, Anthony A. Gal, Suresh S. Ramalingam, Xingming Deng, Michael R. Rossi, Jeanne Kowalski, Fadlo R. Khuri
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 922.
https://doi.org/10.1158/1538-7445.AM2014-922
Published: 01 October 2014
View articletitled, Abstract 922: Evaluating markers of cisplatin sensitivity and survival in small cell lung cancer
Journal Articles

Abstract 3223: EGFR targeted iron-oxide nanoparticles for photodynamic therapy in head and neck cancer

Free
Dongsheng Wang, Xulei Qin, Guoqing Qian, Luma Halig, Baowei Fei, Zhengjia Chen, Zhuo Georgia Chen, Nabil F. Saba, Dong M. Shin, Hong Xu, Andrew Y. Wang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3223.
https://doi.org/10.1158/1538-7445.AM2014-3223
Published: 01 October 2014
View articletitled, Abstract 3223: EGFR targeted iron-oxide nanoparticles for photodynamic therapy in head and neck cancer
Journal Articles

Abstract 4829: Evaluation prognostic significance of circulating tumor cells (CTCs) using multiplexed gold nanoparticles in patients with head and neck cancer

Free
Xu Wang, Ximei Qian, Jonathan J. Beitler, Jun Zhang, Hyunseok Kang, Zhuo (Georgia) Chen, Kelly R. Magliocca, Xiaojing Wang, Zhengjia Chen, Shuming Nie, Dong M. Shin
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4829.
https://doi.org/10.1158/1538-7445.AM2014-4829
Published: 01 October 2014
View articletitled, Abstract 4829: Evaluation prognostic significance of circulating tumor cells (CTCs) using multiplexed gold nanoparticles in patients with head and neck cancer
Journal Articles

Abstract 889: Growth differentiation factor 15 causes increased invasiveness and EMT in HER2-overexpressing breast cancer via activation of p38 MAPK.

Free
Jayashree P. Joshi, Zhengjia Chen, Rita Nahta
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 889.
https://doi.org/10.1158/1538-7445.AM2013-889
Published: 15 April 2013
View articletitled, Abstract 889: Growth differentiation factor 15 causes increased invasiveness and EMT in HER2-overexpressing breast cancer via activation of p38 MAPK.
Journal Articles

Abstract LB-194: Window of opportunity preoperative interrogation of mTOR pathway in patients with resectable non-small cell lung cancer (NSCLC).

Free
Taofeek Kunle Owonikoko, Daniel L. Miller, Seth Force, Gabriel Sica, Scott Kono, Madhusmita Behera, Jennifer Mendel, Zhengjia Chen, Allan Pickens, Robert W. Fu, William F. Auffermann, Jaqueline Rogerio, William E. Torres, Haian Fu, John Hohneker, Shi-Yong Sun, Anthony A. Gal, Suresh S. Ramalingam, Fadlo R. Khuri
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-194.
https://doi.org/10.1158/1538-7445.AM2013-LB-194
Published: 15 April 2013
View articletitled, Abstract LB-194: Window of opportunity preoperative interrogation of mTOR pathway in patients with resectable non-small cell lung cancer (NSCLC).