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Journal Articles

Abstract 3082: The liver microenvironment promotes glycolysis in metastatic colorectal cancer by activating her3

Moeez Ghani Rathore, Kimberly Curry, Christina Boutros, Zhenghe Wang, Jordan Winter, Rui Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3082.
https://doi.org/10.1158/1538-7445.AM2024-3082
Published: 22 March 2024
View article titled, Abstract 3082: The liver microenvironment promotes glycolysis in metastatic colorectal cancer by activating her3
Journal Articles

Abstract 3636: Liver endothelium secreted LRG1 promotes metastatic colorectal cancer growth through the HER3/RSK/EIF4B AXIS

Moeez Ghani Rathore, Michelle Wright, Wei Huang, Derek Taylor, Yamu Li, Jordan Winter, Zhenghe Wang, John Greenwood, Stephen Moss, Rui Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3636.
https://doi.org/10.1158/1538-7445.AM2023-3636
Published: 04 April 2023
View article titled, Abstract 3636: Liver endothelium secreted LRG1 promotes metastatic colorectal cancer growth through the HER3/RSK/EIF4B AXIS
Journal Articles

Abstract 3177: Liver endothelium secreted LRG1 is a novel ligand of HER3 to promote metastatic colorectal cancer growth

Moeez Ghani Rathore, Wei Zhang, Michel'le Wright, Jordan Winter, Yamu Li, Zhenghe Wang, Rui Wang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3177.
https://doi.org/10.1158/1538-7445.AM2022-3177
Published: 15 June 2022
View article titled, Abstract 3177: Liver endothelium secreted LRG1 is a novel ligand of HER3 to promote metastatic colorectal cancer growth
Journal Articles

5-Fluorouracil Enhances the Antitumor Activity of the Glutaminase Inhibitor CB-839 against PIK3CA-Mutant Colorectal Cancers

Yiqing Zhao, Xiujing Feng, Yicheng Chen, J. Eva Selfridge, Shashank Gorityala, Zhanwen Du, Janet M. Wang, Yujun Hao, Gino Cioffi, Ronald A. Conlon, Jill S. Barnholtz-Sloan, Joel Saltzman, Smitha S. Krishnamurthi, Shaveta Vinayak, Martina Veigl, Yan Xu, David L. Bajor, Sanford D. Markowitz, Neal J. Meropol, Jennifer R. Eads, Zhenghe Wang
Journal: Cancer Research
Cancer Res (2020) 80 (21): 4815–4827.
https://doi.org/10.1158/0008-5472.CAN-20-0600
Published: 03 November 2020
View article titled, 5-Fluorouracil Enhances the Antitumor Activity of the Glutaminase Inhibitor CB-839 against <em>PIK3CA</em>-Mutant Colorectal Cancers
Open the PDF for 5-Fluorouracil Enhances the Antitumor Activity of the Glutaminase Inhibitor CB-839 against <em>PIK3CA</em>-Mutant Colorectal Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract LB-294: Targeting glutamine addiction of PIK3CA mutant colorectal cancers: From preclinical models to clinical trials

Yiqing Zhao, Jennifer Eads, David Bajor, zhenghe wang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-294.
https://doi.org/10.1158/1538-7445.AM2019-LB-294
Published: 01 July 2019
View article titled, Abstract LB-294: Targeting glutamine addiction of PIK3CA mutant colorectal cancers: From preclinical models to clinical trials
Journal Articles

Abstract 2379: PTPRT pseudo-phosphatase domain is a denitrase that contributes to its tumor suppressor function

Yiqing Zhao, Zhenghe Wang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2379.
https://doi.org/10.1158/1538-7445.AM2018-2379
Published: 01 July 2018
View article titled, Abstract 2379: PTPRT pseudo-phosphatase domain is a denitrase that contributes to its tumor suppressor function
Journal Articles

Abstract 3126: CEMIP, a secreted protein highly induced in colon cancer and associated with poor patient survival

Stephen P. Fink, Lois Myeroff, Revital Kariv, Petra Platzer, Baozhong Xin, Debra Mikkola, Earl Lawrence, Nathan Morris, Arman Nosrati, James Willson, Joseph Willis, Martina Veigl, Jill Barnholtz-Sloan, Zhenghe Wang, Sanford Markowitz
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3126.
https://doi.org/10.1158/1538-7445.AM2016-3126
Published: 15 July 2016
View article titled, Abstract 3126: CEMIP, a secreted protein highly induced in colon cancer and associated with poor patient survival
Journal Articles

Abstract 1125: Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancers

Yujun Hao, Yardena Samuels, Qingling Li, Dawid Krokowski, Henri Brunengraber, Maria Hatzoglou, Guo-Fang Zhang, Bert Vogelstein, Zhenghe Wang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1125.
https://doi.org/10.1158/1538-7445.AM2015-1125
Published: 01 August 2015
View article titled, Abstract 1125: Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancers
Journal Articles

Abstract 5155: Gain of direct interaction with IRS1 by the helical domain mutations of p110 alpha is crucial for their oncogenic functions.

Yujun Hao, Chao Wang, Weiping Zheng, David Sedwick, Sanford Markowitz, Rob Ewing, Lili Liu, Zhenghe Wang
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5155.
https://doi.org/10.1158/1538-7445.AM2013-5155
Published: 15 April 2013
View article titled, Abstract 5155: Gain of direct interaction with IRS1 by the helical domain mutations of p110 alpha is crucial for their oncogenic functions.
Journal Articles

Abstract 229: Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase non-receptor type 14

Peng Zhang, Zhenghe Wang
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 229.
https://doi.org/10.1158/1538-7445.AM2012-229
Published: 15 April 2012
View article titled, Abstract 229: Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase non-receptor type 14
Journal Articles

microRNA-21 Negatively Regulates Cdc25A and Cell Cycle Progression in Colon Cancer Cells

Peng Wang, Fangdong Zou, Xiaodong Zhang, Hua Li, Austin Dulak, Robert J. Tomko, Jr., John S. Lazo, Zhenghe Wang, Lin Zhang, Jian Yu
Journal: Cancer Research
Cancer Res (2009) 69 (20): 8157–8165.
https://doi.org/10.1158/0008-5472.CAN-09-1996
Published: 14 October 2009
View article titled, microRNA-21 Negatively Regulates Cdc25A and Cell Cycle Progression in Colon Cancer Cells
Open the PDF for microRNA-21 Negatively Regulates Cdc25A and Cell Cycle Progression in Colon Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Ugene, a Newly Identified Protein That Is Commonly Overexpressed in Cancer and Binds Uracil DNA Glycosylase

Chunguang Guo, Xiaodong Zhang, Stephen P. Fink, Petra Platzer, Keith Wilson, James K.V. Willson, Zhenghe Wang, Sanford D. Markowitz
Journal: Cancer Research
Cancer Res (2008) 68 (15): 6118–6126.
https://doi.org/10.1158/0008-5472.CAN-08-1259
Published: 01 August 2008
View article titled, Ugene, a Newly Identified Protein That Is Commonly Overexpressed in Cancer and Binds Uracil DNA Glycosylase
Open the PDF for Ugene, a Newly Identified Protein That Is Commonly Overexpressed in Cancer and Binds Uracil DNA Glycosylase in another window
Includes: Supplementary data
Journal Articles

Three Classes of Genes Mutated In Colorectal Cancers with Chromosomal Instability

Zhenghe Wang, Jordan M. Cummins, Dong Shen, Daniel P. Cahill, Prasad V. Jallepalli, Tian-Li Wang, D. Williams Parsons, Giovanni Traverso, Mark Awad, Natalie Silliman, Janine Ptak, Steve Szabo, James K. V. Willson, Sanford D. Markowitz, Michael L. Goldberg, Roger Karess, Kenneth W. Kinzler, Bert Vogelstein, Victor E. Velculescu, Christoph Lengauer
Journal: Cancer Research
Cancer Res (2004) 64 (9): 2998–3001.
https://doi.org/10.1158/0008-5472.CAN-04-0587
Published: 03 May 2004
View article titled, Three Classes of Genes Mutated In Colorectal Cancers with Chromosomal Instability
Open the PDF for Three Classes of Genes Mutated In Colorectal Cancers with Chromosomal Instability in another window
Journal Articles

Phosphorylation of β-Catenin at S33, S37, or T41 Can Occur in the Absence of Phosphorylation at T45 in Colon Cancer Cells

Zhenghe Wang, Bert Vogelstein, Kenneth W. Kinzler
Journal: Cancer Research
Cancer Res (2003) 63 (17): 5234–5235.
Published: 18 September 2003
View article titled, Phosphorylation of β-Catenin at S33, S37, or T41 Can Occur in the Absence of Phosphorylation at T45 in Colon Cancer Cells
Open the PDF for Phosphorylation of β-Catenin at S33, S37, or T41 Can Occur in the Absence of Phosphorylation at T45 in Colon Cancer Cells in another window