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Journal Articles

CLK1 Activates YAP to Promote Intrahepatic Cholangiocarcinogenesis

Shuai Xue, Xiangzheng Chen, Guoteng Qiu, Haotian Liao, Zeyuan Qiang, Zheng Zhang, Xuping Feng, Lin Xu, Rui Xie, Hongyu Zhou, Jiwei Huang, Yong Zeng, Haichuan Wang
Journal: Cancer Research
Cancer Res (2025) 85 (6): 1035–1048.
https://doi.org/10.1158/0008-5472.CAN-24-0147
Published: 14 March 2025
View article titled, CLK1 Activates YAP to Promote Intrahepatic Cholangiocarcinogenesis
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Includes: Supplementary data
Journal Articles

Abstract 4505: Discovery of a cebrelon-based PTPN1/PTPN2 dual targeting degrader for cancer immunotherapy

Zihan Qu, Yunpeng Bai, Jiajun Dong, Zheng Zhang, Bo Huang, Yiming Miao, Andy W. Tao, Philip S. Low, Zhong-Yin Zhang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4505.
https://doi.org/10.1158/1538-7445.AM2024-4505
Published: 22 March 2024
View article titled, Abstract 4505: Discovery of a cebrelon-based PTPN1/PTPN2 dual targeting degrader for cancer immunotherapy
Journal Articles

Abstract 1973: Discovery of the first-in-class SHP1 covalent inhibitor for cancer immunotherapy

Zihan Qu, Frederick Nguele Meke, Zheng Zhang, Yunpeng Bai, Aaron D. Krabill, Christine S. Muli, Brenson A. Jassim, Jiajun Dong, Jinyue Li, Nguyen Yuyen, Andy W. Tao, Darci T. Trader, Zhong-Yin Zhang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1973.
https://doi.org/10.1158/1538-7445.AM2024-1973
Published: 22 March 2024
View article titled, Abstract 1973: Discovery of the first-in-class SHP1 covalent inhibitor for cancer immunotherapy
Journal Articles

ASS1-Mediated Reductive Carboxylation of Cytosolic Glutamine Confers Ferroptosis Resistance in Cancer Cells

Qiangsheng Hu, Jie Dai, Zheng Zhang, Huansha Yu, Jing Zhang, Xinsheng Zhu, Yi Qin, Lele Zhang, Peng Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (10): 1646–1665.
https://doi.org/10.1158/0008-5472.CAN-22-1999
Published: 15 May 2023
View article titled, ASS1-Mediated Reductive Carboxylation of Cytosolic Glutamine Confers Ferroptosis Resistance in Cancer Cells
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Includes: Supplementary data
Journal Articles

Abstract 3617: METTL16 drives leukemogenesis and maintains leukemia stem cell self-renewal via reprogramming BCAA metabolism

Li Han, Lei Dong, Keith Leung, Zhicong Zhao, Yangchan Li, Ying Qing, Jianhuang Xue, Chao Shen, Zhenhua Chen, Lei Gao, Kitty Wang, Keren Zhou, Wei Li, Brandon Tan, Zheng Zhang, Xi Qin, Rui Su, Xiaolan Deng, Jianjun Chen
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3617.
https://doi.org/10.1158/1538-7445.AM2022-3617
Published: 15 June 2022
View article titled, Abstract 3617: METTL16 drives leukemogenesis and maintains leukemia stem cell self-renewal via reprogramming BCAA metabolism
Journal Articles

Abstract 5685: Recognition of internal mRNA N7-methylguanosine by QKI shuttles transcripts into stress granules and modulates drug resistance

Zhicong Zhao, Lei Dong, Li Han, Yangchan Li, Jianhuang Xue, Keren Zhou, Wei Li, Xiaolan Deng, Ying Qing, Brandon Tan, Zhenhua Chen, Chao Shen, Andrew Small, Kitty Wang, Keith Leung, Zheng Zhang, Xi Qin, Qiang Xia, Rui Su, Jianjun Chen
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5685.
https://doi.org/10.1158/1538-7445.AM2022-5685
Published: 15 June 2022
View article titled, Abstract 5685: Recognition of internal mRNA <em>N7</em>-methylguanosine by QKI shuttles transcripts into stress granules and modulates drug resistance
Journal Articles

MTAP Deficiency–Induced Metabolic Reprogramming Creates a Vulnerability to Cotargeting De Novo Purine Synthesis and Glycolysis in Pancreatic Cancer

Qiangsheng Hu, Yi Qin, Shunrong Ji, Xiuhui Shi, Weixing Dai, Guixiong Fan, Shuo Li, Wenyan Xu, Wensheng Liu, Mengqi Liu, Zheng Zhang, Zeng Ye, Zhijun Zhou, Jingxuan Yang, Qifeng Zhuo, Xianjun Yu, Min Li, Xiaowu Xu
Journal: Cancer Research
Cancer Res (2021) 81 (19): 4964–4980.
https://doi.org/10.1158/0008-5472.CAN-20-0414
Published: 01 October 2021
View article titled, MTAP Deficiency–Induced Metabolic Reprogramming Creates a Vulnerability to Cotargeting <em>De Novo</em> Purine Synthesis and Glycolysis in Pancreatic Cancer
Open the PDF for MTAP Deficiency–Induced Metabolic Reprogramming Creates a Vulnerability to Cotargeting <em>De Novo</em> Purine Synthesis and Glycolysis in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Predicting Responses to Neoadjuvant Chemotherapy in Breast Cancer: ACRIN 6691 Trial of Diffuse Optical Spectroscopic Imaging

Bruce J. Tromberg, Zheng Zhang, Anaïs Leproux, Thomas D. O'Sullivan, Albert E. Cerussi, Philip M. Carpenter, Rita S. Mehta, Darren Roblyer, Wei Yang, Keith D. Paulsen, Brian W. Pogue, Shudong Jiang, Peter A. Kaufman, Arjun G. Yodh, So Hyun Chung, Mitchell Schnall, Bradley S. Snyder, Nola Hylton, David A. Boas, Stefan A. Carp, Steven J. Isakoff, David Mankoff
Journal: Cancer Research
Cancer Res (2016) 76 (20): 5933–5944.
https://doi.org/10.1158/0008-5472.CAN-16-0346
Published: 13 October 2016
View article titled, Predicting Responses to Neoadjuvant Chemotherapy in Breast Cancer: ACRIN 6691 Trial of Diffuse Optical Spectroscopic Imaging
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Includes: Supplementary data
Journal Articles

Inflammation-Dependent IL18 Signaling Restricts Hepatocellular Carcinoma Growth by Enhancing the Accumulation and Activity of Tumor-Infiltrating Lymphocytes

Geoffrey J. Markowitz, Pengyuan Yang, Jing Fu, Gregory A. Michelotti, Rui Chen, Jianhua Sui, Bin Yang, Wen-Hao Qin, Zheng Zhang, Fu-Sheng Wang, Anna Mae Diehl, Qi-Jing Li, Hongyang Wang, Xiao-Fan Wang
Journal: Cancer Research
Cancer Res (2016) 76 (8): 2394–2405.
https://doi.org/10.1158/0008-5472.CAN-15-1548
Published: 14 April 2016
View article titled, Inflammation-Dependent IL18 Signaling Restricts Hepatocellular Carcinoma Growth by Enhancing the Accumulation and Activity of Tumor-Infiltrating Lymphocytes
Open the PDF for Inflammation-Dependent IL18 Signaling Restricts Hepatocellular Carcinoma Growth by Enhancing the Accumulation and Activity of Tumor-Infiltrating Lymphocytes in another window
Includes: Supplementary data
Journal Articles

Abstract A1-04: The role of chromatin remodeler CHD1 in genomic alterations and prostate cancer progression

Wennuan Liu, Lindsey Ulkus Rodrigues, Tao Li, Zheng Zhang, Leah Rider, Lina Romero, Lilly S. Zheng, William B. Isaacs, Scott Cramer, Jianfeng Xu
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_1): A1-04.
https://doi.org/10.1158/1538-7445.TRANSCAGEN-A1-04
Published: 15 November 2015
View article titled, Abstract A1-04: The role of chromatin remodeler CHD1 in genomic alterations and prostate cancer progression
Journal Articles

Abstract S4-04: Predicting pre-surgical neoadjuvant chemotherapy response in breast cancer using diffuse optical spectroscopic imaging (DOSI): Results from the ACRIN 6691 study

Bruce J Tromberg, Zheng Zhang, Anais Leproux, Thomas D O'Sullivan, Albert E Cerussi, Philip Carpenter, Rita Mehta, Darren Roblyer, Wei Yang, Keith D Paulsen, Brian W Pogue, Shudong Jiang, Peter Kaufman, Arjun G Yodh, So-Hyun Chung, Mitchell Schnall, Brad Snyder, Nola Hylton, David A Boas, Stefan A Carp, Steven J Isakoff, David Mankoff
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): S4-04.
https://doi.org/10.1158/1538-7445.SABCS14-S4-04
Published: 01 May 2015
View article titled, Abstract S4-04: Predicting pre-surgical neoadjuvant chemotherapy response in breast cancer using diffuse optical spectroscopic imaging (DOSI): Results from the ACRIN 6691 study
Journal Articles

Abstract 1997: Resveratrol modifies the activity and expression of antioxidant enzymes in somatic cancer cells

Md. Asaduzzaman Khan, Han-chun Chen, Xin-xing Wan, Ai-hua Xu, Dian-zheng Zhang
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1997.
https://doi.org/10.1158/1538-7445.AM2012-1997
Published: 15 April 2012
View article titled, Abstract 1997: Resveratrol modifies the activity and expression of antioxidant enzymes in somatic cancer cells
Journal Articles

Abstract 2741: Applying a biological pathway-based approach to interrogate the genome-wide association data on prostate cancer

Junjie Feng, Jielin Sun, Zheng Zhang, Yi Zhu, Jianfeng Xu
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2741.
https://doi.org/10.1158/1538-7445.AM2011-2741
Published: 15 April 2011
View article titled, Abstract 2741: Applying a biological pathway-based approach to interrogate the genome-wide association data on prostate cancer
Journal Articles

A Novel Prostate Cancer Susceptibility Locus at 19q13

Fang-Chi Hsu, Jielin Sun, Fredrik Wiklund, Sarah D. Isaacs, Kathleen E. Wiley, Lina D. Purcell, Zhengrong Gao, Pär Stattin, Yi Zhu, Seong-Tae Kim, Zheng Zhang, Wennuan Liu, Bao-Li Chang, Patrick C. Walsh, David Duggan, John D. Carpten, William B. Isaacs, Henrik Grönberg, Jianfeng Xu, S. Lilly Zheng
Journal: Cancer Research
Cancer Res (2009) 69 (7): 2720–2723.
https://doi.org/10.1158/0008-5472.CAN-08-3347
Published: 01 April 2009
View article titled, A Novel Prostate Cancer Susceptibility Locus at 19q13
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Includes: Supplementary data
Journal Articles

Sequence Variants at 22q13 Are Associated with Prostate Cancer Risk

Jielin Sun, Siqun Lilly Zheng, Fredrik Wiklund, Sarah D. Isaacs, Ge Li, Kathleen E. Wiley, Seong-Tae Kim, Yi Zhu, Zheng Zhang, Fang-Chi Hsu, Aubrey R. Turner, Pär Stattin, Wennuan Liu, Jin Woo Kim, David Duggan, John Carpten, William Isaacs, Henrik Grönberg, Jianfeng Xu, Bao-Li Chang
Journal: Cancer Research
Cancer Res (2009) 69 (1): 10–15.
https://doi.org/10.1158/0008-5472.CAN-08-3464
Published: 31 December 2008
View article titled, Sequence Variants at 22q13 Are Associated with Prostate Cancer Risk
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Includes: Supplementary data
Journal Articles

Tissue allies of HAb18G/CD147 MAb on cancer tissues

Yu Li, Zheng Zhang, Yang Zhang, Hui Jie Bian, Xiang Min Yang, Zhi-Nan Chen
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1476.
Published: 01 May 2007
View article titled, Tissue allies of HAb18G/CD147 MAb on cancer tissues
Journal Articles

Design of multiplexed oligionucleotide ligation assays for high throughput insertion-deletion polymorphism genotyping

Ryan T. Koehler, Zheng Zhang, Andreas R. Tobler, Sabine Short, Michael Wenz, Francisco M. De La Vega
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 696.
Published: 15 April 2006
View article titled, Design of multiplexed oligionucleotide ligation assays for high throughput insertion-deletion polymorphism genotyping