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Journal Articles

Abstract 6704: Development and characterization of a tri-specific selective CD8 T cell engager (CD8xCD3xCD19) for treatment of B cell lymphoma

Free
Zheng Yang, Wuzhong Shen, Guiyun Tu, Shenjie Xue, Ying Tan, Bingbin Xie, Jason Xu, Hanyang Chen, Shui Liu, Xiaoqiang Yan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6704.
https://doi.org/10.1158/1538-7445.AM2024-6704
Published: 22 March 2024
View articletitled, Abstract 6704: Development and characterization of a tri-specific selective CD8 T cell engager (CD8xCD3xCD19) for treatment of B cell lymphoma
Journal Articles

Nonsense-Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells Harboring SF3B1 or U2AF1 Mutations

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Abigael Cheruiyot, Shan Li, Sridhar Nonavinkere Srivatsan, Tanzir Ahmed, Yuhao Chen, Delphine S. Lemacon, Ying Li, Zheng Yang, Brian A. Wadugu, Wayne A. Warner, Shondra M. Pruett-Miller, Esther A. Obeng, Daniel C. Link, Dalin He, Fei Xiao, Xiaowei Wang, Julie M. Bailis, Matthew J. Walter, Zhongsheng You
Journal: Cancer Research
Cancer Res (2021) 81 (17): 4499–4513.
https://doi.org/10.1158/0008-5472.CAN-20-4016
Published: 01 September 2021
View articletitled, Nonsense-Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells Harboring SF3B1 or U2AF1 Mutations
Open the PDF for Nonsense-Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells Harboring SF3B1 or U2AF1 Mutations in another window
Includes: Supplementary data
Journal Articles

Abstract 1548: Acidic pH selective binding of VISTA to PSGL-1 and anti-tumor activity of combined VISTA and PD-1 blockade

Free
Robert J. Johnston, Linhui Julie Su, Jason Pinckney, David Critton, Arathi Krishnakumar, Martin Corbett, Andrew Rankin, Rose A. DiBella, Lynne Campbell, Xiaodi Deng, Haibin Chen, Alexander Kozhich, Jim Holloway, Zheng Yang, Ginger Rakestraw, Michael Quigley, Alan J. Korman
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1548.
https://doi.org/10.1158/1538-7445.AM2019-1548
Published: 01 July 2019
View articletitled, Abstract 1548: Acidic pH selective binding of VISTA to PSGL-1 and anti-tumor activity of combined VISTA and PD-1 blockade
Journal Articles

Abstract 5789: Discovery of clinical candidate BMS-986158, an oral BET inhibitor, for the treatment of cancer

Free
Ashvinikumar V. Gavai, Derek Norris, David Tortolani, Daniel O'Malley, Yufen Zhao, Claude Quesnelle, Patrice Gill, Wayne Vaccaro, Tram Huynh, Vijay Ahuja, Dharmpal Dodd, Christopher Mussari, Lalgudi Harikrishnan, Muthoni Kamau, John S. Tokarski, Steven Sheriff, Richard Rampulla, Dauh-Rurng Wu, Jianqing Li, Huiping Zhang, Peng Li, Dawn Sun, Henry Yip, Yingru Zhang, Arvind Mathur, Haiying Zhang, Christine Huang, Zheng Yang, Asoka Ranasinghe, Celia D'Arienzo, Ching Su, Gerry Everlof, Lisa Zhang, Nirmala Raghavan, John T. Hunt, Michael Poss, Gregory D. Vite, Richard A. Westhouse, Susan Wee
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5789.
https://doi.org/10.1158/1538-7445.AM2018-5789
Published: 01 July 2018
View articletitled, Abstract 5789: Discovery of clinical candidate BMS-986158, an oral BET inhibitor, for the treatment of cancer
Journal Articles

Abstract 5792: Preclinical antitumor activity of BMS-986158, an oral BET inhibitor, for the treatment of cancer

Free
Susan Wee, Donald Jackson, Heshani Desilva, Maya Dajee, Julie Carman, Petra Ross-MacDonald, Jinping Gan, Richard A. Westhouse, Christine Huang, Zheng Yang, Michael Poss, John T. Hunt, Gregory D. Vite, Ashvinikumar V. Gavai
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5792.
https://doi.org/10.1158/1538-7445.AM2018-5792
Published: 01 July 2018
View articletitled, Abstract 5792: Preclinical antitumor activity of BMS-986158, an oral BET inhibitor, for the treatment of cancer
Journal Articles

Abstract 2782: Examining the dynamic regulation of OX40 following receptor agonism and T-cell activation: Implications for antibody-mediated enhancement of T-cell function

Free
Marie-Claude Gaudreau, Christina Milburn, Chan Gao, Alla Pritsker, Mark Fereshteh, Zheng Yang, Bryan Barnhart, Alan Korman, Michael Quigley
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2782.
https://doi.org/10.1158/1538-7445.AM2018-2782
Published: 01 July 2018
View articletitled, Abstract 2782: Examining the dynamic regulation of OX40 following receptor agonism and T-cell activation: Implications for antibody-mediated enhancement of T-cell function
Journal Articles

Abstract 344: Downregulation of osteoblastic N-cadherin decreases primary multiple myeloma cell - osteoblast interactions

Free
Wenting Zhang, Yexin Gu, Qiaoling Sun, David S. Siegel, Peter Tolias, Zheng Yang, Woo Lee, Jenny Zilberberg
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 344.
https://doi.org/10.1158/1538-7445.AM2015-344
Published: 01 August 2015
View articletitled, Abstract 344: Downregulation of osteoblastic N-cadherin decreases primary multiple myeloma cell - osteoblast interactions
Journal Articles

Abstract 1643: BMS-983970, an oral pan-Notch inhibitor for the treatment of cancer

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Ashvinikumar V. Gavai, Yufen Zhao, Daniel O'Malley, Brian Fink, Claude Quesnelle, Derek Norris, Libing Chen, Soong-Hoon Kim, Wen-Ching Han, Patrice Gill, Weifang Shan, Aaron Balog, Andrew Tebben, Richard Rampulla, Dauh-Rurng Wu, Yingru Zhang, Arvind Mathur, Haiqing Wang, Zheng Yang, Qian Ruan, Robin Moore, David Rodrigues, Asoka Ranasinghe, Celia D'Arienzo, Ching Kim Tye, Ching Su, Gerry Everlof, Melissa Yarde, Mary Ellen Cvijic, Krista Menard, Mei-Li Wen, George Trainor, Bruce Fischer, John Hunt, Gregory Vite, Richard Westhouse, Francis Lee
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1643.
https://doi.org/10.1158/1538-7445.AM2014-1643
Published: 01 October 2014
View articletitled, Abstract 1643: BMS-983970, an oral pan-Notch inhibitor for the treatment of cancer
Journal Articles

Abstract 719: Role of secreted frizzled-related proteins in inhibiting growth and invasion in human osteosarcoma

Free
Pay Chin Leow, Zheng Yang, Pui Lai Rachel Ee
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 719.
https://doi.org/10.1158/1538-7445.AM10-719
Published: 15 April 2010
View articletitled, Abstract 719: Role of secreted frizzled-related proteins in inhibiting growth and invasion in human osteosarcoma
Journal Articles

Curcumin inhibits cell proliferation, invasion and migration in U2OS human osteosarcoma cells

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Pay Chin Leow, Zheng Yang, Pui Lai Rachel Ee
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1200.
Published: 01 May 2008
View articletitled, Curcumin inhibits cell proliferation, invasion and migration in U2OS human osteosarcoma cells
Journal Articles

Pharmacodynamic biomarker

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Feng Roger Luo, Zheng Yang, Amy Camuso, Krista Fager, Kelly McGlinchey, Christine Flefleh, Mei-Li Wen, Richard Smykla, David Kan, Ivan Inigo, Stephen Castaneda, Robert Borzilleri, Louis Lombardo, Robert Wild, John Hunt, Robert Kramer, Francis Y. Lee
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 987–988.
Published: 01 May 2005
View articletitled, Pharmacodynamic biomarker
Journal Articles

BMS-536924, a potent, small molecule inhibitor of the IGF-1 receptor in vitro and in vivo

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Joan M. Carboni, Mark Wittman, Ricardo Attar, Praveen Balimane, Stephen Castaneda, Janet Dell, Marco Gottardis, Ann Greer, Ching-Ping Ho, Chen-Yi Hung, Warren Hurlburt, Ivan Inigo, David Kan, Francis Y. Lee, Aixin Li, Tai-An Lin, Becky Penhallow, Mark Saulnier, Upender Velaparthi, Zheng Yang, Kurt Zimmermann
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1406.
Published: 01 May 2005
View articletitled, BMS-536924, a potent, small molecule inhibitor of the IGF-1 receptor in vitro and in vivo