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Journal Articles

Abstract 3602: Mechanisms of CAR T cell dysfunction and identification of transcription factors that drive the exhaustion phenotype

M. Angela Aznar, Charly R. Good, Shunichiro Kuramitsu, Parisa Samareh, Sangya Agarwal, Greg Donahue, Kenichi Ishiyama, Nils Wellhausen, Austin K. Rennels, Yujie Ma, Lifeng Tian, Sonia Guedan, Katherine A. Alexander, Zhen Zhang, Philipp C. Rommel, Nathan Singh, Karl M. Glastad, Max W. Richardson, Keisuke Watanabe, Janos L. Tanyi, Mark H. O’Hara, Marco Ruella, Simon F. Lacey, Edmund K. Moon, Stephen J. Schuster, Steven M. Albelda, Lewis L. Lanier, Regina M. Young, Shelley L. Berger, Carl H. June
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3602.
https://doi.org/10.1158/1538-7445.AM2022-3602
Published: 15 June 2022
View article titled, Abstract 3602: Mechanisms of CAR T cell dysfunction and identification of transcription factors that drive the exhaustion phenotype
Journal Articles

Abstract LB205: The IRF8-MEF2D transcription factor circuit regulated by a druggable multiple post-translational modification (PTM) reader ZMYND8 in acute myeloid leukemia

Zhendong Cao, Krista A. Budinich, Hua Huang, Bin Lu, Zhen Zhang, Diqiu Ren, Yeqiao Zhou, Yuhan Huang, Bianca Pingul, Molly C. Kingsley, Alexandra K. Lenard, Jun Qi, Martin P. Carroll, Gerd A. Blobel, Robert B. Faryabi, Kathrin M. Bernt, Shelley L. Berger, Junwei Shi
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB205.
https://doi.org/10.1158/1538-7445.AM2021-LB205
Published: 01 July 2021
View article titled, Abstract LB205: The IRF8-MEF2D transcription factor circuit regulated by a druggable multiple post-translational modification (PTM) reader ZMYND8 in acute myeloid leukemia
Journal Articles

Abstract 60: Induction of T cell dysfunction and NK-like T cell differentiation in vitro and in patients after CAR T cell treatment

Charly R. Good, Shunichiro Kuramitsu, Parisa Samareh, Greg Donahue, Kenichi Ishiyama, Yujie Ma, Nils Wellhausen, Lifeng Tian, Sangya Agarwal, Sonia Guedan, M. Angela Aznar, Katherine A. Alexander, Zhen Zhang, Nathan Singh, Max W. Richardson, Keisuke Watanabe, Janos L. Tanyi, Mark H. O'Hara, Marco Ruella, Simon F. Lacey, Edmund K. Moon, Stephen J. Schuster, Steven M. Albelda, Lewis L. Lanier, Regina M. Young, Shelley L. Berger, Carl H. June
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 60.
https://doi.org/10.1158/1538-7445.AM2021-60
Published: 01 July 2021
View article titled, Abstract 60: Induction of T cell dysfunction and NK-like T cell differentiation in vitro and in patients after CAR T cell treatment
Journal Articles

Abstract 5123: Proteogenomic characterization reveals mitotic kinase and replication stress implicated in ovarian high-grade serous cancer

Jason McDermott, Osama Arshad, Vladislav Petyuk, Yi Fu, Marina Gritsenko, Chia-Feng Tsai, Samuel Payne, Mathangi Thiagarajan, Christopher Kinsinger, Ana Robles, Emily Boja, Henry Rodriguez, Daniel Chan, Bing Zhang, Zhen Zhang, Li Ding, Richard Smith, Tao Liu, Karin Rodland
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5123.
https://doi.org/10.1158/1538-7445.AM2020-5123
Published: 15 August 2020
View article titled, Abstract 5123: Proteogenomic characterization reveals mitotic kinase and replication stress implicated in ovarian high-grade serous cancer
Journal Articles

Abstract 2179: Population remodeling in the acquisition of endocrine resistance in breast cancer

Rong Hu, Surojeet Sengupta, Catherine Sevigny, Zhen Zhang, Yue Wang, Robert Clarke
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2179.
https://doi.org/10.1158/1538-7445.AM2018-2179
Published: 01 July 2018
View article titled, Abstract 2179: Population remodeling in the acquisition of endocrine resistance in breast cancer
Journal Articles

Metformin-Induced Reduction of CD39 and CD73 Blocks Myeloid-Derived Suppressor Cell Activity in Patients with Ovarian Cancer

Lifeng Li, Liping Wang, Jieyao Li, Zhirui Fan, Li Yang, Zhen Zhang, Chaoqi Zhang, Dongli Yue, Guohui Qin, Tengfei Zhang, Feng Li, Xinfeng Chen, Yu Ping, Dan Wang, Qun Gao, Qianyi He, Lan Huang, Hong Li, Jianmin Huang, Xuan Zhao, Wenhua Xue, Zhi Sun, Jingli Lu, Jane J. Yu, Jie Zhao, Bin Zhang, Yi Zhang
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (7): 1779–1791.
https://doi.org/10.1158/0008-5472.CAN-17-2460
Published: 01 April 2018
View article titled, Metformin-Induced Reduction of CD39 and CD73 Blocks Myeloid-Derived Suppressor Cell Activity in Patients with Ovarian Cancer
Open the PDF for Metformin-Induced Reduction of CD39 and CD73 Blocks Myeloid-Derived Suppressor Cell Activity in Patients with Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 208: Proteomic measurements of protein abundance and phosphorylation identify novel kinase-substrate relationships in ovarian cancer

Jason E. McDermott, Tao Liu, Samuel Payne, Vladislav Petyuk, Hui Zhang, Zhen Zhang, Daniel Chan, Richard Smith, Karin Rodland, Clinical Proteomic Tumor Analysis Consortium
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 208.
https://doi.org/10.1158/1538-7445.AM2017-208
Published: 01 July 2017
View article titled, Abstract 208: Proteomic measurements of protein abundance and phosphorylation identify novel kinase-substrate relationships in ovarian cancer
Journal Articles

Abstract B2-41: Inference of differential dependency networks between tumor and stroma by integrated UNDO-KDDN software tool

Lulu Chen, Niya Wang, Robert Clarke, Zhen Zhang, Yue Wang
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_2): B2-41.
https://doi.org/10.1158/1538-7445.COMPSYSBIO-B2-41
Published: 15 November 2015
View article titled, Abstract B2-41: Inference of differential dependency networks between tumor and stroma by integrated UNDO-KDDN software tool
Journal Articles

Abstract B1-26: NetFill: A network-based method to identify a parsimonious set of mediators to link mRNA and protein signatures using existing knowledge

Li Chen, Bai Zhang, Hui Zhang, Yue Wang, Daniel W. Chan, Zhen Zhang
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_2): B1-26.
https://doi.org/10.1158/1538-7445.COMPSYSBIO-B1-26
Published: 15 November 2015
View article titled, Abstract B1-26: NetFill: A network-based method to identify a parsimonious set of mediators to link mRNA and protein signatures using existing knowledge
Journal Articles

Abstract 1570: Early Detection Research Network (EDRN) validation of circulating ovarian cancer biomarkers

Steven J. Skates, Karen S. Anderson, Tao Liu, Vathany Kulasingam, Dustin Rabideau, Chaochao Wu, Michael Gillette, Andrew K. Godwin, Nicole Urban, Anna Lokshin, Jeffrey Marks, Eleftherios Diamandis, Zhen Zhang, Sudhir Srivastava, Jacob Kagan, Christos Patriotis, Karin Rodland
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1570.
https://doi.org/10.1158/1538-7445.AM2015-1570
Published: 01 August 2015
View article titled, Abstract 1570: Early Detection Research Network (EDRN) validation of circulating ovarian cancer biomarkers
Journal Articles

Abstract 2485: A novel quantitative proteomics approach to identify proteins that elicit antibody responses in vaccinated pancreatic cancer patients.

Darshil T. Jhaveri, Min-Sik Kim, Lanqing Huang, Rajni Sharma, Zhen Zhang, Robert A. Anders, Akhilesh Pandey, Elizabeth M. Jaffee
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2485.
https://doi.org/10.1158/1538-7445.AM2013-2485
Published: 15 April 2013
View article titled, Abstract 2485: A novel quantitative proteomics approach to identify proteins that elicit antibody responses in vaccinated pancreatic cancer patients.
Journal Articles

Abstract 4797: Global phosphotyrosine survey reveals the evidence of activation of multiple tyrosine kinase signaling pathways in basal-like breast cancer cells

Xinyan Wu, Santosh Renuse, Lily Chen, Raghothama Chaerkady, Min-Sik Kim, Saddiq Zahari, Nandini Sahasrabuddhe, Jun Zhong, Yi Yang, Manoj Kashyap, Arivusudar Marimuthu, Min Ling, Mary Jo Fackler, Vanessa Merino, Zhen Zhang, Saraswati Sukumar, Akhilesh Pandey
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4797.
https://doi.org/10.1158/1538-7445.AM2012-4797
Published: 15 April 2012
View article titled, Abstract 4797: Global phosphotyrosine survey reveals the evidence of activation of multiple tyrosine kinase signaling pathways in basal-like breast cancer cells
Journal Articles

Abstract 4816: OVA1: An in vitro diagnostic multivariate index assay for preoperative assessment of ovarian tumors

Zhen Zhang, Lori Sokoll, Chris Desimone, Leigh Seamon, Rachel Ware, Scott Goodrich, Iwona Podzielinski, Alan Smith, Joseph Santoso, John R. van Nagell, Daniel W. Chan, Frederick R. Ueland
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4816.
https://doi.org/10.1158/1538-7445.AM10-4816
Published: 15 April 2010
View article titled, Abstract 4816: OVA1: An in vitro diagnostic multivariate index assay for preoperative assessment of ovarian tumors
Journal Articles

Abstract #LB-96: Phase III validation of ovarian cancer biomarkers in pre-diagnostic specimens from the PLCO screening trial

Daniel Cramer, Robert Bast, Charlotte Clarke, Kevin Coombes, Eleftherios Diamandis, Eric Fung, Andrew Godwin, Anna Lockshin, Karen Lu, Martin McIntosh, Gil Mor, Steve Skates, Patrick Sluss, Mark Thornquist, Zhen Zhang, Nicole Urban
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-96.
Published: 01 May 2009
View article titled, Abstract #LB-96: Phase III validation of ovarian cancer biomarkers in pre-diagnostic specimens from the PLCO screening trial
Journal Articles

Abstract #5301: Suppression of annexin A11 in ovarian cancer: implications in chemoresistance

Jin Song, Ie-ming Shih, Daniel Chan, Zhen Zhang
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5301.
Published: 01 May 2009
View article titled, Abstract #5301: Suppression of annexin A11 in ovarian cancer: implications in chemoresistance
Journal Articles

Epigenetic silencing of annexin A11 confers chemoresistance to ovarian cancer cells through modulating cell proliferation

Jin Song, Ie-ming Shih, Xiaer Sun, Daniel Chan, Zhen Zhang
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 153.
Published: 01 May 2008
View article titled, Epigenetic silencing of annexin A11 confers chemoresistance to ovarian cancer cells through modulating cell proliferation
Journal Articles

Identification and validation of proteins associated with ‘acquired’ cisplatin resistance in human ovarian cancer

Jin Song, Ie-Ming Shih, Daniel Chan, Zhen Zhang
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 5070.
Published: 01 May 2007
View article titled, Identification and validation of proteins associated with ‘acquired’ cisplatin resistance in human ovarian cancer
Journal Articles

Biomarkers for screening patients with high risk of ovarian and breast cancers

Martin Donach, Grazia Artioli, Giuseppe Banna, Weiwei Feng, Robert C. Bast, Zhen Zhang, Yinhua Yu, Maria O. Nicoletto
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2675.
Published: 01 May 2007
View article titled, Biomarkers for screening patients with high risk of ovarian and breast cancers
Journal Articles

MAPK inhibitors regulate NAP2 and GRO-alpha expression in ovarian cancer cell line with BRAF mutation

Xiaer Sun, Jin Song, IeMing Shih, Daniel Chan, Zhen Zhang
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1829.
Published: 01 May 2007
View article titled, MAPK inhibitors regulate NAP2 and GRO-alpha expression in ovarian cancer cell line with BRAF mutation
Journal Articles

Notch3 Gene Amplification in Ovarian Cancer

Joon T. Park, Mei Li, Kentaro Nakayama, Tsui-Lien Mao, Ben Davidson, Zhen Zhang, Robert J. Kurman, Charles G. Eberhart, Ie-Ming Shih, Tian-Li Wang
Journal: Cancer Research
Cancer Res (2006) 66 (12): 6312–6318.
https://doi.org/10.1158/0008-5472.CAN-05-3610
Published: 15 June 2006
View article titled, <em>Notch3</em> Gene Amplification in Ovarian Cancer
Open the PDF for <em>Notch3</em> Gene Amplification in Ovarian Cancer in another window
Includes: Supplementary data