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Zechen Chong
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Journal Articles

Abstract 5056: Full spectrum of somatic structural variations (SVs) detection in COLO829 with long-read sequencing

Free
Zishan Peng, Zechen Chong
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5056.
https://doi.org/10.1158/1538-7445.AM2025-5056
Published: 21 April 2025
View articletitled, Abstract 5056: Full spectrum of somatic structural variations (SVs) detection in COLO829 with long-read sequencing
Journal Articles

Abstract 1248: Single-cell RNAseq revealed multiple resistance mechanisms in patient-derived xenograft model of rectal cancer during treatment

Free
Yuwei song, Regina K. Irwin, Karin M. Hardiman, Zechen Chong
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1248.
https://doi.org/10.1158/1538-7445.AM2025-1248
Published: 21 April 2025
View articletitled, Abstract 1248: Single-cell RNAseq revealed multiple resistance mechanisms in patient-derived xenograft model of rectal cancer during treatment
Journal Articles

Abstract 6414: Molecular differentiation between complete and incomplete responders to neoadjuvant therapy in rectal cancer

Free
Fengyuan Huang, M. Chandler McLeod, Regina Kay Irwin, Mary Smithson, Zongliang Yue, Min Gao, Karin M. Hardiman, Zechen Chong
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6414.
https://doi.org/10.1158/1538-7445.AM2024-6414
Published: 22 March 2024
View articletitled, Abstract 6414: Molecular differentiation between complete and incomplete responders to neoadjuvant therapy in rectal cancer
Journal Articles

Body Weight Correlates with Molecular Variances in Patients with Cancer

Open Access
Fengyuan Huang, Peng Xu, Zongliang Yue, Yuwei Song, Kaili Hu, Xinyang Zhao, Min Gao, Zechen Chong
Journal: Cancer Research
Cancer Res (2024) 84 (5): 757–770.
https://doi.org/10.1158/0008-5472.CAN-23-1463
Published: 04 March 2024
View articletitled, Body Weight Correlates with Molecular Variances in Patients with Cancer
Open the PDF for Body Weight Correlates with Molecular Variances in Patients with Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2864: Selective suppression of melanoma lacking IFN-γ pathway by JAK inhibition depends on T cells and host TNF signaling

Free
Hongxing Shen, Fengyuan Huang, Xiangmin Zhang, Oluwagbemiga A. Ojo, Yuebin Li, Hoa Quang Trummell, Joshua C. Anderson, John Fiveash, Markus Bredel, Eddy Yang, Christopher Willey, Zechen Chong, James Bonner, Lewis Z. Shi
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2864.
https://doi.org/10.1158/1538-7445.AM2023-2864
Published: 04 April 2023
View articletitled, Abstract 2864: Selective suppression of melanoma lacking IFN-γ pathway by JAK inhibition depends on T cells and host TNF signaling
Journal Articles

Gene Fusion Detection and Characterization in Long-Read Cancer Transcriptome Sequencing Data with FusionSeeker

Open Access
Yu Chen, Yiqing Wang, Weisheng Chen, Zhengzhi Tan, Yuwei Song, Human Genome Structural Variation Consortium, Herbert Chen, Zechen Chong
Journal: Cancer Research
Cancer Res (2023) 83 (1): 28–33.
https://doi.org/10.1158/0008-5472.CAN-22-1628
Published: 04 January 2023
View articletitled, Gene Fusion Detection and Characterization in Long-Read Cancer Transcriptome Sequencing Data with FusionSeeker
Open the PDF for Gene Fusion Detection and Characterization in Long-Read Cancer Transcriptome Sequencing Data with FusionSeeker in another window
Includes: Supplementary data
Journal Articles

Abstract 2101: RNF2 ablation reprograms the tumor-immune microenvironment and stimulates durable NK and CD4+ T cell-dependent anti-tumor immunity

Free
Zhuo Zhang, Lin Luo, Chuan Xing, Yu Chen, Peng Xu, Mao Li, Ling Zeng, Chao Li, Sadashib Ghosh, Deborah Della Manna, Tim Townes, William J. Britt, Narendra Wajapeyee, Barry P. Sleckman, Zechen Chong, Jianmei Wu Leavenworth, Eddy Yang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2101.
https://doi.org/10.1158/1538-7445.AM2022-2101
Published: 15 June 2022
View articletitled, Abstract 2101: RNF2 ablation reprograms the tumor-immune microenvironment and stimulates durable NK and CD4+ T cell-dependent anti-tumor immunity
Journal Articles

Abstract 4079: Single-cell RNA-seq revealed important pathways in response to neoadjuvant therapy resistance in rectal cancer

Free
Yu Chen, Regina K. Irwin, Gregory W. Williams, Mary Smithson, Karin M. Hardiman, Zechen Chong
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4079.
https://doi.org/10.1158/1538-7445.AM2022-4079
Published: 15 June 2022
View articletitled, Abstract 4079: Single-cell RNA-seq revealed important pathways in response to neoadjuvant therapy resistance in rectal cancer
Journal Articles

Abstract A024: Multiple resistance mechanisms identified via Single-cell RNAseq in patient derived xenograft model of rectal cancer during treatment

Free
Yu Chen, Regina K. Irwin, Gregory W. Williams, Mary Smithson, Zechen Chong, Karin M. Hardiman
Journal: Cancer Research
Cancer Res (2022) 82 (10_Supplement): A024.
https://doi.org/10.1158/1538-7445.EVODYN22-A024
Published: 15 May 2022
View articletitled, Abstract A024: Multiple resistance mechanisms identified via Single-cell RNAseq in patient derived xenograft model of rectal cancer during treatment
Journal Articles

Abstract SY10-02: Pan-cancer study of recurrent and heterogeneous RNA aberrations and association with whole-genome variants

Free
Samirkumar Amin, Philip Awadalla, Andrew Biankin, Paul Boutros, Alvis Brazma, Angela Norie Brooks, Claudia Calabrese, David Chang, Aurélien Chateigner, Ken Chen, Zechen Chong, Brian Craft, Chad Creighton, Deniz Demircioğlu, Nuno Fonseca, Milana Frenkel-Morgenstern, Gad Getz, Jonathan Göke, Mary Goldman, Liliana Greger, Syed Haider, Yao He, Katherine Hoadley, Yuan Ji, Andre Kahles, Ekta Khurana, Jan Korbel, Kjong Lehmann, Han Liang, Fenglin Liu, Maximillian Marin, Matthew Meyerson, Akinyemi Ojesina, Francis Ouellette, Chandra Pedamallu, Marc Perry, Gunnar Rätsch, Roland Schwarz, Yuichi Shiraishi, Cameron Soulette, Oliver Stegle, Patrick Tan, Alfonso Valencia, Linda Xiang, Christina Yung, Junjun Zhang, Fan Zhang, Zemin Zhang, Jingchun Zhu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): SY10-02.
https://doi.org/10.1158/1538-7445.AM2017-SY10-02
Published: 01 July 2017
View articletitled, Abstract SY10-02: Pan-cancer study of recurrent and heterogeneous RNA aberrations and association with whole-genome variants
Journal Articles

Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations

Free
Turgut Dogruluk, Yiu Huen Tsang, Maribel Espitia, Fengju Chen, Tenghui Chen, Zechen Chong, Vivek Appadurai, Armel Dogruluk, Agna Karina Eterovic, Penelope E. Bonnen, Chad J. Creighton, Ken Chen, Gordon B. Mills, Kenneth L. Scott
Journal: Cancer Research
Cancer Res (2015) 75 (24): 5341–5354.
https://doi.org/10.1158/0008-5472.CAN-15-1654
Published: 14 December 2015
View articletitled, Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations
Open the PDF for Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations in another window
Includes: Supplementary data
Journal Articles

Abstract P6-06-01: Studies on tumor heterogeneity using a preclinical model of breast cancer caused by genetic alteration of the ATX-LPA axis

Free
Lorenzo Federico, Kang Jin Jeong, Dong Zhang, Zhenlin Ju, Zechen Chong, Jennifer B Dennison, Gordon B Mills
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P6-06-01.
https://doi.org/10.1158/1538-7445.SABCS14-P6-06-01
Published: 01 May 2015
View articletitled, Abstract P6-06-01: Studies on tumor heterogeneity using a preclinical model of breast cancer caused by genetic alteration of the ATX-LPA axis