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Journal Articles

Abstract 4781: Epigenetic regulation of neuroblastoma tumorigenicity through MLL1 and JMJD3 modulation in cancer stem cells

Saurabh Agarwal, Zaowen Chen, Julie A. Tomolonis, Sanjeev A. Vasudevan, Jason M. Shohet
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4781.
https://doi.org/10.1158/1538-7445.AM2017-4781
Published: 01 July 2017
View article titled, Abstract 4781: Epigenetic regulation of neuroblastoma tumorigenicity through MLL1 and JMJD3 modulation in cancer stem cells
Journal Articles

Abstract A15: Epigenetic regulators maintain neuroblastoma cancer stem cells: Model to treatment

Saurabh Agarwal, Zaowen Chen, Sanjeev Vasudevan, Jason M. Shohet
Journal: Cancer Research
Cancer Res (2016) 76 (5_Supplement): A15.
https://doi.org/10.1158/1538-7445.PEDCA15-A15
Published: 04 April 2016
View article titled, Abstract A15: Epigenetic regulators maintain neuroblastoma cancer stem cells: Model to treatment
Journal Articles

G-CSF Promotes Neuroblastoma Tumorigenicity and Metastasis via STAT3-Dependent Cancer Stem Cell Activation

Saurabh Agarwal, Anna Lakoma, Zaowen Chen, John Hicks, Leonid S. Metelitsa, Eugene S. Kim, Jason M. Shohet
Journal: Cancer Research
Cancer Res (2015) 75 (12): 2566–2579.
https://doi.org/10.1158/0008-5472.CAN-14-2946
Published: 14 June 2015
View article titled, G-CSF Promotes Neuroblastoma Tumorigenicity and Metastasis via STAT3-Dependent Cancer Stem Cell Activation
Open the PDF for G-CSF Promotes Neuroblastoma Tumorigenicity and Metastasis via STAT3-Dependent Cancer Stem Cell Activation in another window
Includes: Supplementary data
Journal Articles

Abstract B44: The epigenetic modifier CHAF1A opposes neuroblastoma differentiation via metabolic reprogramming

Eveline Barbieri, Zaowen Chen, Anna Lakoma, Eugene Kim, Jason Shohet
Journal: Cancer Research
Cancer Res (2014) 74 (20_Supplement): B44.
https://doi.org/10.1158/1538-7445.PEDCAN-B44
Published: 09 October 2014
View article titled, Abstract B44: The epigenetic modifier CHAF1A opposes neuroblastoma differentiation via metabolic reprogramming
Journal Articles

Abstract B58: The novel MDM2 inhibitor RG7388 is highly effective against neuroblastoma in vitro and in vivo

Anna Lakoma, Eveline Barbieri, Matthew C. McVay, Zaowen Chen, Charitra Adhikari, Jason M. Shohet, Eugene S. Kim
Journal: Cancer Research
Cancer Res (2014) 74 (20_Supplement): B58.
https://doi.org/10.1158/1538-7445.PEDCAN-B58
Published: 09 October 2014
View article titled, Abstract B58: The novel MDM2 inhibitor RG7388 is highly effective against neuroblastoma in vitro and in vivo
Journal Articles

Histone Chaperone CHAF1A Inhibits Differentiation and Promotes Aggressive Neuroblastoma

Eveline Barbieri, Katleen De Preter, Mario Capasso, Zaowen Chen, Danielle M. Hsu, Gian Paolo Tonini, Steve Lefever, John Hicks, Rogier Versteeg, Andrea Pession, Frank Speleman, Eugene S. Kim, Jason M. Shohet
Journal: Cancer Research
Cancer Res (2014) 74 (3): 765–774.
https://doi.org/10.1158/0008-5472.CAN-13-1315
Published: 02 February 2014
View article titled, Histone Chaperone CHAF1A Inhibits Differentiation and Promotes Aggressive Neuroblastoma
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Includes: Supplementary data
Journal Articles

G-CSF Receptor Positive Neuroblastoma Subpopulations Are Enriched in Chemotherapy-Resistant or Relapsed Tumors and Are Highly Tumorigenic

Danielle M. Hsu, Saurabh Agarwal, Ashley Benham, Cristian Coarfa, Denae N. Trahan, Zaowen Chen, Paris N. Stowers, Amy N. Courtney, Anna Lakoma, Eveline Barbieri, Leonid S. Metelitsa, Preethi Gunaratne, Eugene S. Kim, Jason M. Shohet
Journal: Cancer Research
Cancer Res (2013) 73 (13): 4134–4146.
https://doi.org/10.1158/0008-5472.CAN-12-4056
Published: 30 June 2013
View article titled, G-CSF Receptor Positive Neuroblastoma Subpopulations Are Enriched in Chemotherapy-Resistant or Relapsed Tumors and Are Highly Tumorigenic
Open the PDF for G-CSF Receptor Positive Neuroblastoma Subpopulations Are Enriched in Chemotherapy-Resistant or Relapsed Tumors and Are Highly Tumorigenic in another window
Includes: Supplementary data
Journal Articles

Abstract 3744: G-CSF-dependent regulation of STAT3 in neuroblastoma cancer stem cell subpopulations.

Saurabh Agarwal, Zaowen Chen, Danielle Hsu, Eugene Kim, Jason M. Shohet
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3744.
https://doi.org/10.1158/1538-7445.AM2013-3744
Published: 15 April 2013
View article titled, Abstract 3744: G-CSF-dependent regulation of STAT3 in neuroblastoma cancer stem cell subpopulations.
Journal Articles

Abstract 2291: Oncogenic hsa-miR-1323 down-regulates MYCN/ALK and reveals PAG1 as a novel tumor suppressor for neuroblastoma

Rajib Ghosh, Zaowen Chen, Danielle Patterson, Denae N. Sikorski, Eugene S. Kim, Jason M. Shohet, Preethi H. Gunaratne
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2291.
https://doi.org/10.1158/1538-7445.AM2012-2291
Published: 15 April 2012
View article titled, Abstract 2291: Oncogenic hsa-miR-1323 down-regulates MYCN/ALK and reveals PAG1 as a novel tumor suppressor for neuroblastoma
Journal Articles

A Genome-Wide Search for Promoters That Respond to Increased MYCN Reveals Both New Oncogenic and Tumor Suppressor MicroRNAs Associated with Aggressive Neuroblastoma

Jason M. Shohet, Rajib Ghosh, Cristian Coarfa, Andrew Ludwig, Ashley L. Benham, Zaowen Chen, Danielle M. Patterson, Eveline Barbieri, Pieter Mestdagh, Denae N. Sikorski, Aleksandar Milosavljevic, Eugene S. Kim, Preethi H. Gunaratne
Journal: Cancer Research
Cancer Res (2011) 71 (11): 3841–3851.
https://doi.org/10.1158/0008-5472.CAN-10-4391
Published: 31 May 2011
View article titled, A Genome-Wide Search for Promoters That Respond to Increased MYCN Reveals Both New Oncogenic and Tumor Suppressor MicroRNAs Associated with Aggressive Neuroblastoma
Open the PDF for A Genome-Wide Search for Promoters That Respond to Increased MYCN Reveals Both New Oncogenic and Tumor Suppressor MicroRNAs Associated with Aggressive Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Abstract 674: Cooperative induction of apoptosis through p53 signaling and mTOR inhibition in neuroblastoma

Eveline Barbieri, Zaowen Chen, Andrew Ludwig, Eugene Kim, Danielle Patterson, Denae Sikorski, Jason Shohet
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 674.
https://doi.org/10.1158/1538-7445.AM10-674
Published: 15 April 2010
View article titled, Abstract 674: Cooperative induction of apoptosis through p53 signaling and mTOR inhibition in neuroblastoma
Journal Articles

MYCN-Directed Centrosome Amplification Requires MDM2-Mediated Suppression of p53 Activity in Neuroblastoma Cells

Andrew D. Slack, Zaowen Chen, Andrew D. Ludwig, John Hicks, Jason M. Shohet
Journal: Cancer Research
Cancer Res (2007) 67 (6): 2448–2455.
https://doi.org/10.1158/0008-5472.CAN-06-1661
Published: 15 March 2007
View article titled, MYCN-Directed Centrosome Amplification Requires MDM2-Mediated Suppression of p53 Activity in Neuroblastoma Cells
Open the PDF for MYCN-Directed Centrosome Amplification Requires MDM2-Mediated Suppression of p53 Activity in Neuroblastoma Cells in another window