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Zainab Jagani
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Journal Articles

Abstract 361: Identification of a novel dependence on the SWI/SNF chromatin remodeling complex in uveal melanoma

Florencia Rago, Xiaoqin Xiang, Aurore Desplat, Emilie Niemezyk, David Ruddy, Grainne Kerr, Eusebio Manchado Robles, Deborah Castelletti, Zainab Jagani
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 361.
https://doi.org/10.1158/1538-7445.AM2018-361
Published: 01 July 2018
View article titled, Abstract 361: Identification of a novel dependence on the SWI/SNF chromatin remodeling complex in uveal melanoma
Journal Articles

Abstract 1025: Controlled and endogenous depletion of a synthetic lethal target in human cancer cell lines via SMASh degron engineering

Florencia Rago, Matthew T. Dimare, Geoffrey Bushold, Avnish Kapoor, Hyo-eun C. Bhang, Zainab Jagani
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1025.
https://doi.org/10.1158/1538-7445.AM2017-1025
Published: 01 July 2017
View article titled, Abstract 1025: Controlled and endogenous depletion of a synthetic lethal target in human cancer cell lines via SMASh degron engineering
Journal Articles

Abstract LB-126: ARID1B is a specific vulnerability in ARID1A-mutant cancers

Katherine Helming, Xiaofeng Wang, Boris Wilson, Francisca Vazquez, Jeffrey Haswell, Haley Manchester, Youngha Kim, Gregory V. Kryukov, Mahmoud Ghandi, Andrew J. Aguirre, Zainab Jagani, Zhong Wang, Levi Garraway, William Hahn, Charles Roberts
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-126.
https://doi.org/10.1158/1538-7445.AM2014-LB-126
Published: 01 October 2014
View article titled, Abstract LB-126: ARID1B is a specific vulnerability in ARID1A-mutant cancers
Journal Articles

Abstract 444: BRM/SMARCA2 is a critical synthetic lethal target in BRG1-deficient cancers

Mariela Jaskelioff, Gregory Hoffman, Rami Rahal, Kay Xiang, Kristy Haas, Veronica Saenz-Vash, Huili Zhai, Nicholas Keen, Frank Stegmeier, Zainab Jagani
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 444.
https://doi.org/10.1158/1538-7445.AM2014-444
Published: 01 October 2014
View article titled, Abstract 444: BRM/SMARCA2 is a critical synthetic lethal target in BRG1-deficient cancers
Journal Articles

The Polycomb Group Protein Bmi-1 Is Essential for the Growth of Multiple Myeloma Cells

Zainab Jagani, Dmitri Wiederschain, Alice Loo, Dan He, Rebecca Mosher, Paul Fordjour, John Monahan, Michael Morrissey, Yung-Mae Yao, Christoph Lengauer, Markus Warmuth, William R. Sellers, Marion Dorsch
Journal: Cancer Research
Cancer Res (2010) 70 (13): 5528–5538.
https://doi.org/10.1158/0008-5472.CAN-09-4229
Published: 30 June 2010
View article titled, The Polycomb Group Protein Bmi-1 Is Essential for the Growth of Multiple Myeloma Cells
Open the PDF for The Polycomb Group Protein Bmi-1 Is Essential for the Growth of Multiple Myeloma Cells in another window
Includes: Supplementary data
Journal Articles

Proteasome Inhibition Causes Regression of Leukemia and Abrogates BCR-ABL–Induced Evasion of Apoptosis in Part through Regulation of Forkhead Tumor Suppressors

Zainab Jagani, Keli Song, Jeffery L. Kutok, M. Rajan Dewar, Armelle Melet, Tanya Santos, Alexandra Grassian, Saghi Ghaffari, Catherine Wu, Ruibao Ren, Heather Yeckes Rodin, Kenneth Miller, Roya Khosravi-Far
Journal: Cancer Research
Cancer Res (2009) 69 (16): 6546–6555.
https://doi.org/10.1158/0008-5472.CAN-09-0605
Published: 12 August 2009
View article titled, Proteasome Inhibition Causes Regression of Leukemia and Abrogates BCR-ABL–Induced Evasion of Apoptosis in Part through Regulation of Forkhead Tumor Suppressors
Open the PDF for Proteasome Inhibition Causes Regression of Leukemia and Abrogates BCR-ABL–Induced Evasion of Apoptosis in Part through Regulation of Forkhead Tumor Suppressors in another window
Includes: Supplementary data
Journal Articles

PI3K Pathway Activation Mediates Resistance to MEK Inhibitors in KRAS Mutant Cancers

Susan Wee, Zainab Jagani, Kay Xiaoqin Xiang, Alice Loo, Marion Dorsch, Yung-Mae Yao, William R. Sellers, Christoph Lengauer, Frank Stegmeier
Journal: Cancer Research
Cancer Res (2009) 69 (10): 4286–4293.
https://doi.org/10.1158/0008-5472.CAN-08-4765
Published: 15 May 2009
View article titled, PI3K Pathway Activation Mediates Resistance to MEK Inhibitors in KRAS Mutant Cancers
Open the PDF for PI3K Pathway Activation Mediates Resistance to MEK Inhibitors in KRAS Mutant Cancers in another window
Includes: Supplementary data
Journal Articles

Oncogene-induced regulation of proteasomal degradation pathway: mechanism for tumorigenecity

Keli Song, Zainab Jagani, Nordine Benhaga, Jeffery Kutok, Roya Khosravi-Far
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 456.
Published: 01 May 2007
View article titled, Oncogene-induced regulation of proteasomal degradation pathway: mechanism for tumorigenecity
Journal Articles

Proteasomal degradation pathway in oncogene-induced evasion from apoptosis: Targeted therapy in leukemia

Zainab Jagani, Keli Song, Nordine Benhaga, Armelle Melet, Alexandra Grassian, Dale Mierke, Jeff Kutok, Roya Khosravi-Far
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 715.
Published: 15 April 2006
View article titled, Proteasomal degradation pathway in oncogene-induced evasion from apoptosis: Targeted therapy in leukemia
Journal Articles

Oncogene-induced regulation of proteasomal degradation pathway:A mechanism for tumorigenicity

Zainab Jagani, Keli Song, Nordine Benhaga, Saghi Ghaffari, Harvey Lodish, Jeffery Kutok, Roya Khosravi-Far
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 609.
Published: 01 May 2005
View article titled, Oncogene-induced regulation of proteasomal degradation pathway:A mechanism for tumorigenicity
Journal Articles

Bcr-Abl induced evasion from apoptosis: A mechanism for tumorigenicity.

Zainab Jagani, Saghi Ghaffari, Claire Kitidis, Harvey Lodish, Roya Khosravi-Far
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 776.
Published: 01 April 2004
View article titled, Bcr-Abl induced evasion from apoptosis: A mechanism for tumorigenicity.