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Yuzhuo Wang
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Journal Articles

Abstract 1625: Redox homeostasis is a therapeutic vulnerability in lethal neuroendocrine prostate cancer

Mu-En Wang, Wei-Ling Tu, Ji-Hoon Kim, Yi Lu, Alyssa Bawcom, Andrew J. Armstrong, Qianben Wang, Yuzhuo Wang, Jiaoti Huang, Ming Chen
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1625.
https://doi.org/10.1158/1538-7445.AM2025-1625
Published: 21 April 2025
View articletitled, Abstract 1625: Redox homeostasis is a therapeutic vulnerability in lethal neuroendocrine prostate cancer
Journal Articles

Abstract 3299: Harnessing PIKfyve as a therapeutic vulnerability in neuroendocrine prostate cancer

Yang Zheng, Kyle Garcia Rogers, Arya Gopal Kamat, Sarah Nicole Yee, Rahul Mannan, Xia Jiang, Rowena Kannaiyan, Xuhong Cao, Yuzhuo Wang, Yuanyuan Qiao, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3299.
https://doi.org/10.1158/1538-7445.AM2024-3299
Published: 22 March 2024
View articletitled, Abstract 3299: Harnessing PIKfyve as a therapeutic vulnerability in neuroendocrine prostate cancer
Journal Articles

Abstract 2898: Development of the lipid kinase PIKfyve PROTAC degrader against neuroendocrine prostate cancer

Yuanyuan Qiao, Chungen Li, Yang Zheng, Xia Jiang, Sarah Nicole Yee, Caleb Cheng, Yi Bao, Yuping Zhang, Yuzhuo Wang, Zhen Wang, Ke Ding, Arul Chinnaiyan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2898.
https://doi.org/10.1158/1538-7445.AM2024-2898
Published: 22 March 2024
View articletitled, Abstract 2898: Development of the lipid kinase PIKfyve PROTAC degrader against neuroendocrine prostate cancer
Journal Articles

Abstract 948: A novel combinatorial therapy for lethal neuroendocrine prostate cancer

Mu-En Wang, Wei-Ling Tu, Yi Lu, Jinjin Wu, Alyssa Bawcom, Andrew J. Armstrong, Qianben Wang, Yuzhuo Wang, Jiaoti Huang, Ming Chen
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 948.
https://doi.org/10.1158/1538-7445.AM2024-948
Published: 22 March 2024
View articletitled, Abstract 948: A novel combinatorial therapy for lethal neuroendocrine prostate cancer
Journal Articles

Abstract 1723: Ferroptosis is a novel therapeutic target for RB1 deficient lethal prostate cancer

Mu-En Wang, Jiaqi Chen, Yi Lu, Jinjin Wy, Jianhong Ou, John Asara, Andrew Armstrong, Qianben Wang, Lei Li, Yuzhuo Wang, Jiaoti Huang, Ming Chen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1723.
https://doi.org/10.1158/1538-7445.AM2023-1723
Published: 04 April 2023
View articletitled, Abstract 1723: Ferroptosis is a novel therapeutic target for RB1 deficient lethal prostate cancer
Journal Articles

Abstract 4011: Preferential cytotoxicity of ESK981 in neuroendocrine prostate cancer

Yang Zheng, Kyle J. Garcia-Rogers, Yi Bao, Rahul Mannan, Tongchen He, Sarah N. Yee, Caleb Cheng, Xia Jiang, Isabella E. Taylor, Xuhong Cao, Yuzhuo Wang, Yuanyuan Qiao, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4011.
https://doi.org/10.1158/1538-7445.AM2023-4011
Published: 04 April 2023
View articletitled, Abstract 4011: Preferential cytotoxicity of ESK981 in neuroendocrine prostate cancer
Journal Articles

Immunotherapeutic Targeting and PET Imaging of DLL3 in Small-Cell Neuroendocrine Prostate Cancer

Jonathan Chou, Emily A. Egusa, Sinan Wang, Michelle L. Badura, Fei Lee, Anil P. Bidkar, Jun Zhu, Tanushree Shenoy, Kai Trepka, Troy M. Robinson, Veronica Steri, Jiaoti Huang, Yuzhuo Wang, Eric J. Small, Emily Chan, Bradley A. Stohr, Alan Ashworth, Brant Delafontaine, Sylvie Rottey, Keegan S. Cooke, Nooshin Hashemi Sadraei, Brian Yu, Mark Salvati, Julie M. Bailis, Felix Y. Feng, Robert R. Flavell, Rahul Aggarwal
Journal: Cancer Research
Cancer Res (2023) 83 (2): 301–315.
https://doi.org/10.1158/0008-5472.CAN-22-1433
Published: 18 January 2023
View articletitled, Immunotherapeutic Targeting and PET Imaging of DLL3 in Small-Cell Neuroendocrine Prostate Cancer
Open the PDF for Immunotherapeutic Targeting and PET Imaging of DLL3 in Small-Cell Neuroendocrine Prostate Cancer in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract 395: Characterizing the role of chaperone-mediated autophagy in prostate cancer treatment resistance

Nicholas Nikesitch, Eliana Beraldi, Fan Zhang, Hans Adomat, Robert Bell, Ladan Fazli, Christopher Wells, Nicholas Pinette, Yuzhuo Wang, Martin Gleave
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 395.
https://doi.org/10.1158/1538-7445.AM2022-395
Published: 15 June 2022
View articletitled, Abstract 395: Characterizing the role of chaperone-mediated autophagy in prostate cancer treatment resistance
Journal Articles

Abstract 5469: Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer

Lanbo Xiao, Abhijit Parolia, Yuanyuan Qiao, Pushpinder Bawa Pushpinder, Sanjana Eyunni, Rahul Mannan, Sandra E. Carson, Yu Chang, Xiaoju Wang, Yuping Zhang, Josh Vo, Steven Kregel, Stephanie A. Simko, Andrew D. Delekta, Mustapha Jaber, Heng Zheng, Ingrid Apel, Lisa McMurry, Fengyun Su, Rui Wang, Sylvia Wang, Sanjita Sasmal, Leena K. Satyam, Subhendu Mukherjee, Chandrasekhar AbbinenI, Kiran Aithal, Mital S. Bhakta, Jay Ghurye, Xuhong Cao, Nora M. Navone, Alexey Nesvizhskii, Rohit Mehra, Ulka Vaishampayan, Marco Blanchette, Yuzhuo Wang, Susanta Samajdar, Murali Ramachandra, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5469.
https://doi.org/10.1158/1538-7445.AM2022-5469
Published: 15 June 2022
View articletitled, Abstract 5469: Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer
Journal Articles

Abstract 3592: Targeting SWI/SNF ATPases in enhancer-addicted human cancers

Abhijit Parolia, Lanbo Xiao, Yuanyuan Qiao, Pushpinder Bawa, Sanjana Eyunni, Eleanor Young, Rahul Mannan, Sandra E. Carson, Yu Chang, Yuping Zhang, James George, Mustapha Jaber, Fengyun Su, Rui Wang, Sanjita Sasmal, Leena Khare, Subhendu Mukerjee, Chandrasekhar AbbinenI, Kiran Aithal, Xuhong Cao, Yuzhuo Wang, Susanta Samajdar, Murali Ramachandra, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3592.
https://doi.org/10.1158/1538-7445.AM2022-3592
Published: 15 June 2022
View articletitled, Abstract 3592: Targeting SWI/SNF ATPases in enhancer-addicted human cancers
Journal Articles

Abstract 5729: Dynamic phase separation of the androgen receptor and its coactivators to regulate gene expression

Fan Zhang, Maitree Biswas, Joseph Lee, Shreyas Lingadahalli, Samantha Wong, Christopher Wells, Neetu Saxena, Bei Sun, Ana K. Parra-Nuñez, Christophe Sanchez, Jane Foo, Novia Chan, Lauren Ung, Nabeel Khan, Umut Berkay Altıntaş, Jennifer M. Bui, Yuzhuo Wang, Ladan Fazli, Paul S. Rennie, Nathan Lack, Artem Cherkasov, Martin E. Gleave, Joerg Gsponer, Nada Lallous
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5729.
https://doi.org/10.1158/1538-7445.AM2022-5729
Published: 15 June 2022
View articletitled, Abstract 5729: Dynamic phase separation of the androgen receptor and its coactivators to regulate gene expression
Journal Articles

Abstract 3698: Conditionally reprogrammed cells from patient-derived xenograft to model neuroendocrine prostate cancer development

Xinpei Ci, Jun Hao, Xin Dong, Hui Xue, Rebecca Wu, Anne M. Haegert, Colin C. Collins, Dong Lin, Yuzhuo Wang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3698.
https://doi.org/10.1158/1538-7445.AM2019-3698
Published: 01 July 2019
View articletitled, Abstract 3698: Conditionally reprogrammed cells from patient-derived xenograft to model neuroendocrine prostate cancer development
Journal Articles

Abstract 3410: Copy number estimation from whole-exome sequencing in tumors

Shawn Anderson, Zhiwei Che, Raja Keshavan, Andrea O'Hara, Dong Lin, Yuzhuo Wang, Colin Collins, Soheil Shams
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3410.
https://doi.org/10.1158/1538-7445.AM2018-3410
Published: 01 July 2018
View articletitled, Abstract 3410: Copy number estimation from whole-exome sequencing in tumors
Journal Articles

Abstract 238: Interaction analysis between germline susceptibility loci and somatic alterations in lung cancer

Yuzhuo Wang, Cheng Wang, Meng Zhu, Guangfu Jin, Hongbing Shen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 238.
https://doi.org/10.1158/1538-7445.AM2018-238
Published: 01 July 2018
View articletitled, Abstract 238: Interaction analysis between germline susceptibility loci and somatic alterations in lung cancer
Journal Articles

Abstract 1918: Patient-derived hormone-naive prostate cancer xenograft models reveal GRB10 as an AR-repressed gene driving the development of castration-resistant prostate cancer

Jun Hao, Xinpei Ci, Hui Xue, Rebecca Wu, Xin Dong, Fang Zhang, Sifeng Qu, Fan Zhang, Anne M. Haegert, Peter W. Gout, Colin Collins, Martin E. Gleave, Dong Lin, Yuzhuo Wang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1918.
https://doi.org/10.1158/1538-7445.AM2018-1918
Published: 01 July 2018
View articletitled, Abstract 1918: Patient-derived hormone-naive prostate cancer xenograft models reveal GRB10 as an AR-repressed gene driving the development of castration-resistant prostate cancer
Journal Articles

Abstract 773: A heterochromatin gene signature unveils HP1α mediating neuroendocrine prostate cancer development and aggressiveness

Xinpei Ci, Jun Hao, Xin Dong, Stephen Y. Choi, Hui Xue, Sifeng Qu, Ladan Fazli, Francesco Crea, Christopher Ong, Amina Zoubeidi, Housheng H. He, Martin E. Gleave, Colin C. Collins, Dong Lin, Yuzhuo Wang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 773.
https://doi.org/10.1158/1538-7445.AM2018-773
Published: 01 July 2018
View articletitled, Abstract 773: A heterochromatin gene signature unveils HP1α mediating neuroendocrine prostate cancer development and aggressiveness
Journal Articles

Heterochromatin Protein 1α Mediates Development and Aggressiveness of Neuroendocrine Prostate Cancer

Xinpei Ci, Jun Hao, Xin Dong, Stephen Y. Choi, Hui Xue, Rebecca Wu, Sifeng Qu, Peter W. Gout, Fang Zhang, Anne M. Haegert, Ladan Fazli, Francesco Crea, Christopher J. Ong, Amina Zoubeidi, Housheng H. He, Martin E. Gleave, Colin C. Collins, Dong Lin, Yuzhuo Wang
Journal: Cancer Research
Cancer Res (2018) 78 (10): 2691–2704.
https://doi.org/10.1158/0008-5472.CAN-17-3677
Published: 14 May 2018
View articletitled, Heterochromatin Protein 1α Mediates Development and Aggressiveness of Neuroendocrine Prostate Cancer
Open the PDF for Heterochromatin Protein 1α Mediates Development and Aggressiveness of Neuroendocrine Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 4420: Elevated glycolytic gene signature in patient-derived neuroendocrine prostate cancer xenograft models and its clinical relevance

Stephen Y. Choi, Susan L. Ettinger, Dong Lin, Hui Xue, Robert H. Bell, Fan Mo, Michael Pollak, Colin C. Collins, Yuzhuo Wang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4420.
https://doi.org/10.1158/1538-7445.AM2017-4420
Published: 01 July 2017
View articletitled, Abstract 4420: Elevated glycolytic gene signature in patient-derived neuroendocrine prostate cancer xenograft models and its clinical relevance
Journal Articles

Abstract 3189: Neuronal transcription factor BRN2 is an androgen suppressed driver of neuroendocrine differentiation in prostate cancer

Jennifer L. Bishop, Daksh Thaper, Sepideh Vahid, Ravi S. Munuganti, Paul Ahn, Alastair Davies, Kirsi Ketola, Ka Mun Nip, Dong Lin, Yuzhuo Wang, Himisha Beltran, Amina Zoubeidi
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3189.
https://doi.org/10.1158/1538-7445.AM2017-3189
Published: 01 July 2017
View articletitled, Abstract 3189: Neuronal transcription factor BRN2 is an androgen suppressed driver of neuroendocrine differentiation in prostate cancer
Journal Articles

Abstract 1834: Semaphorin 3C is an androgen receptor-regulated gene

Kevin J. Tam, Kush Dalal, Michael Hsing, Chi Wing Cheng, Yan Ting Chiang, Aishwariya Sharma, James W. Peacock, Artem Cherkasov, Yuzhuo Wang, Martin E. Gleave, Paul S. Rennie, Christopher J. Ong
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1834.
https://doi.org/10.1158/1538-7445.AM2016-1834
Published: 15 July 2016
View articletitled, Abstract 1834: Semaphorin 3C is an androgen receptor-regulated gene