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Journal Articles

Oncogenic ASPM Is a Regulatory Hub of Developmental and Stemness Signaling in Cancers

Kelvin K. Tsai, Byoung-Il Bae, Chung-Chi Hsu, Li-Hsin Cheng, Yuval Shaked

Cancer Res (2023) 83 (18): 2993–3000.

https://doi.org/10.1158/0008-5472.CAN-23-0158

Published: 15 September 2023

View article titled, Oncogenic ASPM Is a Regulatory Hub of Developmental and Stemness Signaling in Cancers

Includes: Supplementary data

Journal Articles

T Cells Promote Metastasis by Regulating Extracellular Matrix Remodeling following Chemotherapy

Jozafina Haj-Shomaly, Avital Vorontsova, Tamar Barenholz-Cohen, Oshrat Levi-Galibov, Mahesh Devarasetty, Michael Timaner, Ziv Raviv, Tim J. Cooper, Shay Soker, Peleg Hasson, Daphne Weihs, Ruth Scherz-Shouval, Yuval Shaked

Cancer Res (2022) 82 (2): 278–291.

https://doi.org/10.1158/0008-5472.CAN-21-1012

Published: 15 January 2022

View article titled, T Cells Promote Metastasis by Regulating Extracellular Matrix Remodeling following Chemotherapy

Includes: Supplementary data

Journal Articles

Abstract LB-401: A proteomics-based biomarker discovery platform for predicting clinical response to immune checkpoint inhibitor therapy in non-small cell lung cancer

Michal Harel, Irena Khononov, Eran Issler, Coren Lahav, Ella Fremder, Eyal Jacob, Nili Dahan, Ziv Raviv, Avishag Shkedy, Reema Jacob, Adam Dicker, Haim Bar, Ofer Sharon, Yuval Shaked

Cancer Res (2020) 80 (16_Supplement): LB-401.

https://doi.org/10.1158/1538-7445.AM2020-LB-401

Published: 15 August 2020

View article titled, Abstract LB-401: A proteomics-based biomarker discovery platform for predicting clinical response to immune checkpoint inhibitor therapy in non-small cell lung cancer

Journal Articles

Heparanase and Chemotherapy Synergize to Drive Macrophage Activation and Enhance Tumor Growth

Udayan Bhattacharya, Lilach Gutter-Kapon, Tal Kan, Ilanit Boyango, Uri Barash, Shi-Ming Yang, JingJing Liu, Miriam Gross-Cohen, Ralph D. Sanderson, Yuval Shaked, Neta Ilan, Israel Vlodavsky

Cancer Res (2020) 80 (1): 57–68.

https://doi.org/10.1158/0008-5472.CAN-19-1676

Published: 03 January 2020

View article titled, Heparanase and Chemotherapy Synergize to Drive Macrophage Activation and Enhance Tumor Growth

Includes: Supplementary data

Journal Articles

Therapy-Educated Mesenchymal Stem Cells Enrich for Tumor-Initiating Cells

Michael Timaner, Nitzan Letko-Khait, Ruslana Kotsofruk, Madeleine Benguigui, Ofrat Beyar-Katz, Chen Rachman-Tzemah, Ziv Raviv, Tomer Bronshtein, Marcelle Machluf, Yuval Shaked

Cancer Res (2018) 78 (5): 1253–1265.

https://doi.org/10.1158/0008-5472.CAN-17-1547

Published: 28 February 2018

View article titled, Therapy-Educated Mesenchymal Stem Cells Enrich for Tumor-Initiating Cells

Includes: Supplementary data

Journal Articles

Evidence Implicating Immunological Host Effects in the Efficacy of Metronomic Low-Dose Chemotherapy

Yuval Shaked, Elizabeth Pham, Santosh Hariharan, Ksenia Magidey, Ofrat Beyar-Katz, Ping Xu, Shan Man, Florence T.H. Wu, Valeria Miller, David Andrews, Robert S. Kerbel

Cancer Res (2016) 76 (20): 5983–5993.

https://doi.org/10.1158/0008-5472.CAN-16-0136

Published: 13 October 2016

View article titled, Evidence Implicating Immunological Host Effects in the Efficacy of Metronomic Low-Dose Chemotherapy

Includes: Supplementary data

Journal Articles

Abstract B42: Dysregulation of key microRNAs controlling tumor-host interactions triggers escape from osteosarcoma dormancy

Galia Tiram, Paula Ofek, Taturo Udagawa, Noam Shomron, Maayan Roniger, Batsheva Kerem, Yuval Shaked, Sarit Aviel-Ronen, Iris Barshack, Marcelo Calderon, Rainer Haag, Ronit Satchi-Fainaro

Cancer Res (2016) 76 (15_Supplement): B42.

https://doi.org/10.1158/1538-7445.TME16-B42

Published: 28 July 2016

View article titled, Abstract B42: Dysregulation of key microRNAs controlling tumor-host interactions triggers escape from osteosarcoma dormancy

Journal Articles

Abstract B59: The dual effect of therapy-induced IL-1β expression on tumor progression: Role of tumor-associated macrophages

Tali Voloshin, Dror Alishekevitz, Valeria Miller, Lika Isakov, Rotem Bril, Moran Benhar, Roney Apte, Yuval Shaked

Cancer Res (2013) 73 (3_Supplement): B59.

https://doi.org/10.1158/1538-7445.TIM2013-B59

Published: 01 May 2014

View article titled, Abstract B59: The dual effect of therapy-induced IL-1β expression on tumor progression: Role of tumor-associated macrophages

Journal Articles

Abstract LB-343: Host response to paclitaxel chemotherapy promotes metastasis via the secretion of VEGF-C by macrophages.

Svetlana Gingis-Velitski, Orit Kaidar-Person, Dror Alishekevitz, Rotem Bril, Ella Fremder, Yuval Shaked

Cancer Res (2013) 73 (8_Supplement): LB-343.

https://doi.org/10.1158/1538-7445.AM2013-LB-343

Published: 15 April 2013

View article titled, Abstract LB-343: Host response to paclitaxel chemotherapy promotes metastasis via the secretion of VEGF-C by macrophages.

Journal Articles

Abstract 4377: Metronomic oral prodrug of gemcitabine (LY2334737) causes antitumor effects with concomitant increase in intratumoral blood flow

Giulio Francia, Yuval Shaked, Kae Hashimoto, John Sun, Ping Xu, Shan Man, Christina Hackl, Julie Stewart, Anne H. Dantzig, Mark Uhlik, Stuart Foster, Robert S. Kerbel

Cancer Res (2012) 72 (8_Supplement): 4377.

https://doi.org/10.1158/1538-7445.AM2012-4377

Published: 15 April 2012

View article titled, Abstract 4377: Metronomic oral prodrug of gemcitabine (LY2334737) causes antitumor effects with concomitant increase in intratumoral blood flow

Journal Articles

Abstract 4362: Identification and isolation of host factors in response to therapy: an approach to identify new targets for cancer therapy

Svetlana Gingis-Velitski, Tali Voloshin, Ella Fremder, Yuval Shaked

Cancer Res (2012) 72 (8_Supplement): 4362.

https://doi.org/10.1158/1538-7445.AM2012-4362

Published: 15 April 2012

View article titled, Abstract 4362: Identification and isolation of host factors in response to therapy: an approach to identify new targets for cancer therapy

Journal Articles

Combined Blockade of Integrin-α4β1 Plus Cytokines SDF-1α or IL-1β Potently Inhibits Tumor Inflammation and Growth

Michael C. Schmid, Christie J. Avraamides, Philippe Foubert, Yuval Shaked, Sang Won Kang, Robert S. Kerbel, Judith A. Varner

Cancer Res (2011) 71 (22): 6965–6975.

https://doi.org/10.1158/0008-5472.CAN-11-0588

Published: 13 November 2011

View article titled, Combined Blockade of Integrin-α4β1 Plus Cytokines SDF-1α or IL-1β Potently Inhibits Tumor Inflammation and Growth

Includes: Supplementary data

Journal Articles

Host Response to Short-term, Single-Agent Chemotherapy Induces Matrix Metalloproteinase-9 Expression and Accelerates Metastasis in Mice

Svetlana Gingis-Velitski, David Loven, Liat Benayoun, Michal Munster, Rotem Bril, Tali Voloshin, Dror Alishekevitz, Francesco Bertolini, Yuval Shaked

Cancer Res (2011) 71 (22): 6986–6996.

https://doi.org/10.1158/0008-5472.CAN-11-0629

Published: 13 November 2011

View article titled, Host Response to Short-term, Single-Agent Chemotherapy Induces Matrix Metalloproteinase-9 Expression and Accelerates Metastasis in Mice

Includes: Supplementary data

Journal Articles

Abstract 4357: Tumor initiating cells promoting angiogenesis as a model of tumor re-growth following chemotherapy

Liat Benayoun, Tali Voloshin, Svetlana Gingis-Veltski, Rotem Segev, Michal Munster, Rotem Bril, Yuval Shaked

Cancer Res (2011) 71 (8_Supplement): 4357.

https://doi.org/10.1158/1538-7445.AM2011-4357

Published: 15 April 2011

View article titled, Abstract 4357: Tumor initiating cells promoting angiogenesis as a model of tumor re-growth following chemotherapy

Journal Articles

Abstract 382: Platelets are implicated in the rapid host responses induced by cytotoxic chemotherapy which limit its anti-tumor efficacy

Chlöe C. Milsom, Yuval Shaked, Christina R. Lee, Shan Man, Robert S. Kerbel

Cancer Res (2010) 70 (8_Supplement): 382.

https://doi.org/10.1158/1538-7445.AM10-382

Published: 15 April 2010

View article titled, Abstract 382: Platelets are implicated in the rapid host responses induced by cytotoxic chemotherapy which limit its anti-tumor efficacy

Journal Articles

Contribution of Granulocyte Colony-Stimulating Factor to the Acute Mobilization of Endothelial Precursor Cells by Vascular Disrupting Agents

Yuval Shaked, Terence Tang, Jill Woloszynek, Laura G. Daenen, Shan Man, Ping Xu, Shi-Rong Cai, Jeffrey M. Arbeit, Emile E. Voest, David J. Chaplin, Jon Smythe, Adrian Harris, Paul Nathan, Ian Judson, Gordon Rustin, Francesco Bertolini, Daniel C. Link, Robert S. Kerbel

Cancer Res (2009) 69 (19): 7524–7528.

https://doi.org/10.1158/0008-5472.CAN-09-0381

Published: 01 October 2009

View article titled, Contribution of Granulocyte Colony-Stimulating Factor to the Acute Mobilization of Endothelial Precursor Cells by Vascular Disrupting Agents

Includes: Supplementary data

Journal Articles

Glioma Tumor Stem-Like Cells Promote Tumor Angiogenesis and Vasculogenesis via Vascular Endothelial Growth Factor and Stromal-Derived Factor 1

Chris Folkins, Yuval Shaked, Shan Man, Terence Tang, Christina R. Lee, Zhenping Zhu, Robert M. Hoffman, Robert S. Kerbel

Cancer Res (2009) 69 (18): 7243–7251.

https://doi.org/10.1158/0008-5472.CAN-09-0167

Published: 14 September 2009

View article titled, Glioma Tumor Stem-Like Cells Promote Tumor Angiogenesis and Vasculogenesis via Vascular Endothelial Growth Factor and Stromal-Derived Factor 1

Includes: Supplementary data

Journal Articles

Glioma tumor stem-like cells promote tumor angiogenesis via VEGF- and SDF1-mediated promotion of endothelial cell activity and recruitment of bone marrow-derived endothelial progenitor cells

Chris Folkins, Yuval Shaked, Shan Man, Terence Tang, Christina Lee, Robert Kerbel

Cancer Res (2008) 68 (9_Supplement): 1097.

Published: 01 May 2008

View article titled, Glioma tumor stem-like cells promote tumor angiogenesis via VEGF- and SDF1-mediated promotion of endothelial cell activity and recruitment of bone marrow-derived endothelial progenitor cells

Journal Articles

Molecular mechanisms responsible for vascular disrupting agent-induced acute mobilization and tumor homing of circulating endothelial progenitor cells.

Yuval Shaked, Terence Tang, Jill Mayer, Laura Daenen, Shan Man, Ping Xu, Shi-Rong Cai, John Wong, Jeffrey Arbeit, Judy Varner, Emile Voest, David Chaplin, Adrian Harris, Paul Nathan, Gordon Rustin, Francesco Bertolini, Daniel Link, Robert Kerbel

Cancer Res (2008) 68 (9_Supplement): 5854.

Published: 01 May 2008

View article titled, Molecular mechanisms responsible for vascular disrupting agent-induced acute mobilization and tumor homing of circulating endothelial progenitor cells.

Journal Articles

Chemotherapy-induced surge in endothelial precursor cells: Implications for antiangiogenic drugs as chemosensitizing agents

Yuval Shaked, Erik Henke, Jeanine Roodhart, Patrizia Mancuso, Marlies Langenberg, Marco Colleoni, Shan Man, Ping Xu, Laura Daenen, Urban Emmenegger, Terence Tang, Francesco Bertolini, Emile Voest, Robert Benezra, Robert Kerbel

Cancer Res (2008) 68 (9_Supplement): 1120.

Published: 01 May 2008

View article titled, Chemotherapy-induced surge in endothelial precursor cells: Implications for antiangiogenic drugs as chemosensitizing agents

NARROW

Oncogenic ASPM Is a Regulatory Hub of Developmental and Stemness Signaling in Cancers

T Cells Promote Metastasis by Regulating Extracellular Matrix Remodeling following Chemotherapy

Abstract LB-401: A proteomics-based biomarker discovery platform for predicting clinical response to immune checkpoint inhibitor therapy in non-small cell lung cancer

Heparanase and Chemotherapy Synergize to Drive Macrophage Activation and Enhance Tumor Growth

Therapy-Educated Mesenchymal Stem Cells Enrich for Tumor-Initiating Cells

Evidence Implicating Immunological Host Effects in the Efficacy of Metronomic Low-Dose Chemotherapy

Abstract B42: Dysregulation of key microRNAs controlling tumor-host interactions triggers escape from osteosarcoma dormancy

Abstract B59: The dual effect of therapy-induced IL-1β expression on tumor progression: Role of tumor-associated macrophages

Abstract LB-343: Host response to paclitaxel chemotherapy promotes metastasis via the secretion of VEGF-C by macrophages.

Abstract 4377: Metronomic oral prodrug of gemcitabine (LY2334737) causes antitumor effects with concomitant increase in intratumoral blood flow

Abstract 4362: Identification and isolation of host factors in response to therapy: an approach to identify new targets for cancer therapy

Combined Blockade of Integrin-α4β1 Plus Cytokines SDF-1α or IL-1β Potently Inhibits Tumor Inflammation and Growth

Host Response to Short-term, Single-Agent Chemotherapy Induces Matrix Metalloproteinase-9 Expression and Accelerates Metastasis in Mice

Abstract 4357: Tumor initiating cells promoting angiogenesis as a model of tumor re-growth following chemotherapy

Abstract 382: Platelets are implicated in the rapid host responses induced by cytotoxic chemotherapy which limit its anti-tumor efficacy

Contribution of Granulocyte Colony-Stimulating Factor to the Acute Mobilization of Endothelial Precursor Cells by Vascular Disrupting Agents

Glioma Tumor Stem-Like Cells Promote Tumor Angiogenesis and Vasculogenesis via Vascular Endothelial Growth Factor and Stromal-Derived Factor 1

Glioma tumor stem-like cells promote tumor angiogenesis via VEGF- and SDF1-mediated promotion of endothelial cell activity and recruitment of bone marrow-derived endothelial progenitor cells

Molecular mechanisms responsible for vascular disrupting agent-induced acute mobilization and tumor homing of circulating endothelial progenitor cells.

Chemotherapy-induced surge in endothelial precursor cells: Implications for antiangiogenic drugs as chemosensitizing agents

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