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Journal Articles

Abstract 763: The regulation of miR-125b1-peroxiredoxin like 2A anti-oxidative activity in oral squamous cell carcinoma

Yi-Fen Chen, Yun-Yen Wei, Cheng-Chieh Yang, Kuo-Wei Chang, Shu-Chun Lin
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 763.
https://doi.org/10.1158/1538-7445.AM2019-763
Published: 01 July 2019
View article titled, Abstract 763: The regulation of miR-125b1-<em>peroxiredoxin like 2A</em> anti-oxidative activity in oral squamous cell carcinoma
Journal Articles

Abstract 4422: miR-125b mediates oral cancer suppression by targeting the antioxidative gene peroxiredoxin like 2A (PRXL2A)

Yi-Fen Chen, Yun-Yen Wei, Cheng-Chieh Yang, Chung-Ji Liu, Kuo-Wei Chang, Shu-Chun Lin
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4422.
https://doi.org/10.1158/1538-7445.AM2018-4422
Published: 01 July 2018
View article titled, Abstract 4422: <em>miR-125b</em> mediates oral cancer suppression by targeting the antioxidative gene <em>peroxiredoxin like 2A</em> (<em>PRXL2A</em>)
Journal Articles

Abstract 4880: Characterization of genetic concordance between primary tumor cells, circulating tumor cells, and metastatic tumor cells from patients with prostate cancer

Lixin Yang, Linling Chen, Yafan Wang, Jeremy Jones, Yun Yen, Sofia Loera, Raju Pillai, Peiguo Chu, Dennis Weisenburger
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4880.
https://doi.org/10.1158/1538-7445.AM2015-4880
Published: 01 August 2015
View article titled, Abstract 4880: Characterization of genetic concordance between primary tumor cells, circulating tumor cells, and metastatic tumor cells from patients with prostate cancer
Journal Articles

Abstract 3017: Ribonucleotide reductase promotes uracil-mediated genome instability in tumor progression

Chih-Wei Chen, Ning Tsao, Yun Yen, Christine E. Lehman, Yuh-Hwa Wang, Chian-Feng Chen, Tse-Hsiang Wu, Sui-Chih Tien, Ming-Hsiang Lee, Zee-Fen Chang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3017.
https://doi.org/10.1158/1538-7445.AM2015-3017
Published: 01 August 2015
View article titled, Abstract 3017: Ribonucleotide reductase promotes uracil-mediated genome instability in tumor progression
Journal Articles

Abstract 3953: Enhanced radiation reponse in MCF-7 radioresistant cells by targeting Peroxiredoxin II

Tieli Wang, Anthony Joseph Diaz, Jian-Jian Li, Yun Yen, Daniel Tamae
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3953.
https://doi.org/10.1158/1538-7445.AM2014-3953
Published: 01 October 2014
View article titled, Abstract 3953: Enhanced radiation reponse in MCF-7 radioresistant cells by targeting Peroxiredoxin II
Journal Articles

Bcl2 Induces DNA Replication Stress by Inhibiting Ribonucleotide Reductase

Maohua Xie, Yun Yen, Taofeek K. Owonikoko, Suresh S. Ramalingam, Fadlo R. Khuri, Walter J. Curran, Paul W. Doetsch, Xingming Deng
Journal: Cancer Research
Cancer Res (2014) 74 (1): 212–223.
https://doi.org/10.1158/0008-5472.CAN-13-1536-T
Published: 05 January 2014
View article titled, Bcl2 Induces DNA Replication Stress by Inhibiting Ribonucleotide Reductase
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Includes: Supplementary data
Journal Articles

A Small-Molecule Blocking Ribonucleotide Reductase Holoenzyme Formation Inhibits Cancer Cell Growth and Overcomes Drug Resistance

Bingsen Zhou, Leila Su, Shuya Hu, Weidong Hu, M.L. Richard Yip, Jun Wu, Shikha Gaur, D. Lynne Smith, Yate-Ching Yuan, Timothy W. Synold, David Horne, Yun Yen
Journal: Cancer Research
Series: Author Choice
Cancer Res (2013) 73 (21): 6484–6493.
https://doi.org/10.1158/0008-5472.CAN-13-1094
Published: 31 October 2013
View article titled, A Small-Molecule Blocking Ribonucleotide Reductase Holoenzyme Formation Inhibits Cancer Cell Growth and Overcomes Drug Resistance
Open the PDF for A Small-Molecule Blocking Ribonucleotide Reductase Holoenzyme Formation Inhibits Cancer Cell Growth and Overcomes Drug Resistance in another window
Includes: Supplementary data
Journal Articles

Abstract 4356: EphB4 as a novel therapeutic target for head-neck SCC.

Ren Liu, Hai-yun Yen, Rizwan Masood, Uttam Sinha, Anthony El-Khoueiry, Stephen Liu, Barbara Gitlitz, Parkash S. Gill
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4356.
https://doi.org/10.1158/1538-7445.AM2013-4356
Published: 15 April 2013
View article titled, Abstract 4356: EphB4 as a novel therapeutic target for head-neck SCC.
Journal Articles

Abstract A9: De novo sequencing of circulating microRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer

Xiwei Wu, George Somlo, Melanie Palomares, Yun Yen, John Rossi, Harry Gao, Shizhen Emily Wang
Journal: Cancer Research
Cancer Res (2012) 72 (2_Supplement): A9.
https://doi.org/10.1158/1538-7445.NONRNA12-A9
Published: 03 April 2013
View article titled, Abstract A9: De novo sequencing of circulating microRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer
Journal Articles

Amplification of FRS2 and Activation of FGFR/FRS2 Signaling Pathway in High-Grade Liposarcoma

Keqiang Zhang, Kevin Chu, Xiwei Wu, Hanlin Gao, Jinhui Wang, Yate-Ching Yuan, Sofia Loera, Kimberley Ho, Yafan Wang, Warren Chow, Frank Un, Peiguo Chu, Yun Yen
Journal: Cancer Research
Cancer Res (2013) 73 (4): 1298–1307.
https://doi.org/10.1158/0008-5472.CAN-12-2086
Published: 14 February 2013
View article titled, Amplification of FRS2 and Activation of FGFR/FRS2 Signaling Pathway in High-Grade Liposarcoma
Open the PDF for Amplification of FRS2 and Activation of FGFR/FRS2 Signaling Pathway in High-Grade Liposarcoma in another window
Includes: Supplementary data
Journal Articles

Abstract 699: The prognostic value of DNA polymerase ≤ for breast cancers

Xiyong Liu, Hang Zhang, Sofia Loera, Yasheng Huang, Xutao Deng, Zheng Liu, Suzhan Zhang, Lirong Chen, Shu Zheng, Peiguo Chu, Kai-Ming Chou, Yun Yen
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 699.
https://doi.org/10.1158/1538-7445.AM2012-699
Published: 15 April 2012
View article titled, Abstract 699: The prognostic value of DNA polymerase ≤ for breast cancers
Journal Articles

Abstract 3279: Potential beneficial effects of the BRCA1 mutation carrier state on bone strength

Ying Liu, Hai-Yun Yen, Yankel Gabet, Nancy Wu, Malcolm C. Pike, Baruch Frenkel, Robert Maxson, Louis Dubeau
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3279.
https://doi.org/10.1158/1538-7445.AM2012-3279
Published: 15 April 2012
View article titled, Abstract 3279: Potential beneficial effects of the BRCA1 mutation carrier state on bone strength
Journal Articles

Abstract 5583: Decrease in expression of Gadd45 is associated with gemcitabine and hydroxyurea resistance in human head and neck squamous-cell carcinoma

Keqiang Zhang, Charles Kim, Xiwei Wu, Yafan Wang, Sofia Loera, Stephen Shibata, Yun Yen
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5583.
https://doi.org/10.1158/1538-7445.AM2012-5583
Published: 15 April 2012
View article titled, Abstract 5583: Decrease in expression of Gadd45 is associated with gemcitabine and hydroxyurea resistance in human head and neck squamous-cell carcinoma
Journal Articles

Abstract 4755: The role of a pair of cysteine residues in the redox properties of human ribonucleotide reductase small subunits hp53R2 and hRRM2

Bingsen Zhou, Leila Su, Shuya Hu, Yun Yen
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4755.
https://doi.org/10.1158/1538-7445.AM2012-4755
Published: 15 April 2012
View article titled, Abstract 4755: The role of a pair of cysteine residues in the redox properties of human ribonucleotide reductase small subunits hp53R2 and hRRM2
Journal Articles

Abstract 706: Ribonucleotide reductase small subunit M2 is a potential prognostic biomarker in human epidermal growth factor receptor 2- positive and triple negative breast cancers

Hang Zhang, Xiyong Liu, Xutao Deng, Zheng Liu, Charles Warden, Yasheng Huang, Rui Bai, Huarong Chen, Sofia Loera, Jiaping Peng, Lun Zhou, Weiting Ge, Hanguang Hu, Suzhan Zhang, Peiguo Chu, Shu Zheng, Yun Yen
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 706.
https://doi.org/10.1158/1538-7445.AM2012-706
Published: 15 April 2012
View article titled, Abstract 706: Ribonucleotide reductase small subunit M2 is a potential prognostic biomarker in human epidermal growth factor receptor 2- positive and triple negative breast cancers
Journal Articles

Combining Histone Deacetylase Inhibitor Vorinostat with Aurora Kinase Inhibitors Enhances Lymphoma Cell Killing with Repression of c-Myc, hTERT, and microRNA Levels

Leo Kretzner, Anna Scuto, Pamela M. Dino, Claudia M. Kowolik, Jun Wu, Patrick Ventura, Richard Jove, Stephen J. Forman, Yun Yen, Mark H. Kirschbaum
Journal: Cancer Research
Cancer Res (2011) 71 (11): 3912–3920.
https://doi.org/10.1158/0008-5472.CAN-10-2259
Published: 31 May 2011
View article titled, Combining Histone Deacetylase Inhibitor Vorinostat with Aurora Kinase Inhibitors Enhances Lymphoma Cell Killing with Repression of c-Myc, hTERT, and microRNA Levels
Open the PDF for Combining Histone Deacetylase Inhibitor Vorinostat with Aurora Kinase Inhibitors Enhances Lymphoma Cell Killing with Repression of c-Myc, hTERT, and microRNA Levels in another window
Includes: Supplementary data
Journal Articles

Ribonucleotide Reductase Small Subunit M2B Prognoses Better Survival in Colorectal Cancer

Xiyong Liu, Lily Lai, Xiaochen Wang, Lijun Xue, Sofia Leora, Jun Wu, Shuya Hu, Keqiang Zhang, Mei-Ling Kuo, Lun Zhou, Hang Zhang, Yafan Wang, Yan Wang, Bingsen Zhou, Rebecca A. Nelson, Shu Zheng, Suzhan Zhang, Peiguo Chu, Yun Yen
Journal: Cancer Research
Cancer Res (2011) 71 (9): 3202–3213.
https://doi.org/10.1158/0008-5472.CAN-11-0054
Published: 29 April 2011
View article titled, Ribonucleotide Reductase Small Subunit M2B Prognoses Better Survival in Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Abstract 1196: FZD7 plays a critical role in triple negative breast cancer proliferation

Lixin Yang, Xiwei Wu, Xutao Deng, Sean Lau, George Somlo, Yun Yen
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1196.
https://doi.org/10.1158/1538-7445.AM2011-1196
Published: 15 April 2011
View article titled, Abstract 1196: FZD7 plays a critical role in triple negative breast cancer proliferation
Journal Articles

Abstract 1306: A Phase 1b/2a study of CRLX101, a novel nanopharmaceutical of camptothecin, in solid tumor cancer patients who have failed standard therapy

Glen Weiss, Yun Yen, Jeffrey Neidhart, Cissy S. Young, Sara Weiss, John Ryan
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1306.
https://doi.org/10.1158/1538-7445.AM2011-1306
Published: 15 April 2011
View article titled, Abstract 1306: A Phase 1b/2a study of CRLX101, a novel nanopharmaceutical of camptothecin, in solid tumor cancer patients who have failed standard therapy
Journal Articles

Abstract 3258: Development of novel ribonucleotide reductase inhibitors: A story from structural analysis to preclinical study

Bingsen Zhou, Leila Su, Yate-Ching Yuan, Shuya Hu, Yun Yen
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3258.
https://doi.org/10.1158/1538-7445.AM2011-3258
Published: 15 April 2011
View article titled, Abstract 3258: Development of novel ribonucleotide reductase inhibitors: A story from structural analysis to preclinical study