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Journal Articles

Abstract 6896: A pan-KRAS degrader for the treatment of KRAS-mutant cancers

Free
Mu-Sheng Zeng, Jie Yang, Qiao-Li Wang Wang, Guan-Nan Wang, Jia-Cong Ye, Zi-Qian Li, Jing-Yun Wang, Zhao-Hui Liang, Shu-Xin Li, Cong Sun, Wen-Ting Liao, Yi-Jun Gao, Jing Wang, Yong Mao, Chunjing Yu, Guo-Kai Feng
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6896.
https://doi.org/10.1158/1538-7445.AM2025-6896
Published: 21 April 2025
View articletitled, Abstract 6896: A pan-KRAS degrader for the treatment of KRAS-mutant cancers
Journal Articles

Abstract CT170: Trial in progress: A phase 1, first in human clinical trial for T-Plex, a multiplexed, enhanced T cell receptor-engineered T cell therapy (TCR-T) for solid tumors

Free
Justin Moser, Brian Pico, Brian Henick, Rom Leidner, Jared Weiss, James Isaacs, Jaspreet Grewal, Michael Hurwitz, Jim Murray, Marlyane Motta, Yun Wang, Shrikanta Chattopadhyay, Debora Barton, Gavin MacBeath, Sajeve Thomas
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT170.
https://doi.org/10.1158/1538-7445.AM2024-CT170
Published: 05 April 2024
View articletitled, Abstract CT170: Trial in progress: A phase 1, first in human clinical trial for T-Plex, a multiplexed, enhanced T cell receptor-engineered T cell therapy (TCR-T) for solid tumors
Journal Articles

Abstract CT151: Trial in progress:A phase 1 trial of TSC-100 and TSC-101, engineered T cell therapies that target minor histocompatibility antigens to eliminate residual disease after hematopoietic cell transplantation

Free
Monzr Al Malki, Alla Keyzner, Hyung Suh, Uday Popat, Chen Yi-Bin, Saar Gill, Melhem Solh, Joseph Uberti, Iris Isufi, Erica Buonomo, Yun Wang, Jim Murray, Gavin MacBeath, Debora Barton, Shrikanta Chattopadhyay, Ran Reshef
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT151.
https://doi.org/10.1158/1538-7445.AM2024-CT151
Published: 05 April 2024
View articletitled, Abstract CT151: Trial in progress:A phase 1 trial of TSC-100 and TSC-101, engineered T cell therapies that target minor histocompatibility antigens to eliminate residual disease after hematopoietic cell transplantation
Journal Articles

Abstract 4687: Primary study on the anticancer role of BAM15 in lung cancer cells

Free
Mei-yin Zhang, Yue-Ning Wang, Yu-Feng Zhou, Shuo-Cheng Wang, Shi-Juan Mai, Hui-Yun Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4687.
https://doi.org/10.1158/1538-7445.AM2024-4687
Published: 22 March 2024
View articletitled, Abstract 4687: Primary study on the anticancer role of BAM15 in lung cancer cells
Journal Articles

Abstract LB154: Circ0003039 interacts with calreticulin to inhibit the progression of hepatocellular carcinoma by suppressing wnt/beta-catenin signaling pathway

Free
Yue-Ning Wang, Yu-Feng Zhou, Ji Liu, Mei-Yin Zhang, Shuo-Cheng Wang, Shi-Juan Mai, Hui-Yun Wang
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB154.
https://doi.org/10.1158/1538-7445.AM2023-LB154
Published: 14 April 2023
View articletitled, Abstract LB154: Circ0003039 interacts with calreticulin to inhibit the progression of hepatocellular carcinoma by suppressing wnt/beta-catenin signaling pathway
Journal Articles

WNT5a Signaling through ROR2 Activates the Hippo Pathway to Suppress YAP1 Activity and Tumor Growth

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Keshan Wang, Fen Ma, Seiji Arai, Yun Wang, Andreas Varkaris, Larysa Poluben, Olga Voznesensky, Fang Xie, Xiaoping Zhang, Xin Yuan, Steven P. Balk
Journal: Cancer Research
Cancer Res (2023) 83 (7): 1016–1030.
https://doi.org/10.1158/0008-5472.CAN-22-3003
Published: 04 April 2023
View articletitled, WNT5a Signaling through ROR2 Activates the Hippo Pathway to Suppress YAP1 Activity and Tumor Growth
Open the PDF for WNT5a Signaling through ROR2 Activates the Hippo Pathway to Suppress YAP1 Activity and Tumor Growth in another window
Includes: Supplementary data
Journal Articles

mTORC1 Promotes ARID1A Degradation and Oncogenic Chromatin Remodeling in Hepatocellular Carcinoma

Available to Purchase
Shanshan Zhang, Yu-Feng Zhou, Jian Cao, Stephen K. Burley, Hui-Yun Wang, X.F. Steven Zheng
Journal: Cancer Research
Cancer Res (2021) 81 (22): 5652–5665.
https://doi.org/10.1158/0008-5472.CAN-21-0206
Published: 15 November 2021
View articletitled, mTORC1 Promotes ARID1A Degradation and Oncogenic Chromatin Remodeling in Hepatocellular Carcinoma
Open the PDF for mTORC1 Promotes ARID1A Degradation and Oncogenic Chromatin Remodeling in Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

MYC-Activated LncRNA MNX1-AS1 Promotes the Progression of Colorectal Cancer by Stabilizing YB1

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Qi-Nian Wu, Xiao-Jing Luo, Jia Liu, Yun-Xin Lu, Yun Wang, Jingjing Qi, Ze-Xian Liu, Qi-Tao Huang, Ze-Kun Liu, Jia-Bin Lu, Ying Jin, Heng-Ying Pu, Pei-Shan Hu, Jia-Bo Zheng, Zhao-Lei Zeng, Huai-Qiang Ju, Dan Xie, Qi Zhao, Ruihua Xu
Journal: Cancer Research
Cancer Res (2021) 81 (10): 2636–2650.
https://doi.org/10.1158/0008-5472.CAN-20-3747
Published: 15 May 2021
View articletitled, MYC-Activated LncRNA MNX1-AS1 Promotes the Progression of Colorectal Cancer by Stabilizing YB1
Open the PDF for MYC-Activated LncRNA MNX1-AS1 Promotes the Progression of Colorectal Cancer by Stabilizing YB1 in another window
Includes: Supplementary data
Journal Articles

Abstract 1416: Long non-coding RNA GAN1 inhibits tumor progression by regulating the mir-26a/PTEN axis in lung cancer

Free
Rui-qi Wang, Xiao-Ran Long, Mei-Yin Zhang, Dong-Ni Chen, Zhe-Sheng Wen, Shi-Juan Mai, Hui-Yun Wang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1416.
https://doi.org/10.1158/1538-7445.AM2020-1416
Published: 15 August 2020
View articletitled, Abstract 1416: Long non-coding RNA GAN1 inhibits tumor progression by regulating the mir-26a/PTEN axis in lung cancer
Journal Articles

Abstract 1289: CSDE1 mediated translation reprogramming under stress

Free
Jiajia Cui, Ao-Xiang Guo, Lei-Yun Wang, Ji-Ye Yin
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1289.
https://doi.org/10.1158/1538-7445.AM2020-1289
Published: 15 August 2020
View articletitled, Abstract 1289: CSDE1 mediated translation reprogramming under stress
Journal Articles

Abstract 5977: Maf1 suppresses hepatocarcinogenesis in mice through inhibition of Akt-mTOR signaling

Free
Di Cao, Xiaoxing Li, Yang Yang, Yu-Feng Zhou, Mei-Yin Zhang, Shan-Shan Zhang, Qian-Nan Ren, Hui-Zhong Zhang, Yao-Jun Zhang, Shi-Juan Mai, Hui-Yun Wang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5977.
https://doi.org/10.1158/1538-7445.AM2020-5977
Published: 15 August 2020
View articletitled, Abstract 5977: Maf1 suppresses hepatocarcinogenesis in mice through inhibition of Akt-mTOR signaling
Journal Articles

Correction: ME1 Regulates NADPH Homeostasis to Promote Gastric Cancer Growth and Metastasis

Free
Yun-Xin Lu, Huai-Qiang Ju, Ze-Xian Liu, Dong-Liang Chen, Yun Wang, Qi Zhao, Qi-Nian Wu, Zhao-lei Zeng, Hai-Bo Qiu, Pei-Shan Hu, Zhi-Qiang Wang, Dong-Sheng Zhang, Feng Wang, Rui-Hua Xu
Journal: Cancer Research
Cancer Res (2019) 79 (14): 3789.
https://doi.org/10.1158/0008-5472.CAN-19-1611
Published: 15 July 2019
View articletitled, Correction: ME1 Regulates NADPH Homeostasis to Promote Gastric Cancer Growth and Metastasis
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Journal Articles

Abstract 1358: Translational regulation of DNA repair: The mechanism under cap-independent translational regulation of RPA2

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Jia-Jia Cui, Lei-Yun Wang, Ao-Xiang Guo, Ji-Ye Yin
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1358.
https://doi.org/10.1158/1538-7445.AM2018-1358
Published: 01 July 2018
View articletitled, Abstract 1358: Translational regulation of DNA repair: The mechanism under cap-independent translational regulation of RPA2
Journal Articles

ME1 Regulates NADPH Homeostasis to Promote Gastric Cancer Growth and Metastasis

Free
Yun-Xin Lu, Huai-Qiang Ju, Ze-Xian Liu, Dong-Liang Chen, Yun Wang, Qi Zhao, Qi-Nian Wu, Zhao-lei Zeng, Hai-Bo Qiu, Pei-Shan Hu, Zhi-Qiang Wang, Dong-Sheng Zhang, Feng Wang, Rui-Hua Xu
Journal: Cancer Research
Cancer Res (2018) 78 (8): 1972–1985.
https://doi.org/10.1158/0008-5472.CAN-17-3155
Published: 12 April 2018
View articletitled, ME1 Regulates NADPH Homeostasis to Promote Gastric Cancer Growth and Metastasis
Open the PDF for ME1 Regulates NADPH Homeostasis to Promote Gastric Cancer Growth and Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 1093: Synergistic action of sorafenib and carfilzomib against hepatocellular carcinoma in vitro and in vivo

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Chao Jiang, Rui Xu, Xiao-Xing Li, Hui-Yun Wang, X.F. Steven Zheng
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1093.
https://doi.org/10.1158/1538-7445.AM2017-1093
Published: 01 July 2017
View articletitled, Abstract 1093: Synergistic action of sorafenib and carfilzomib against hepatocellular carcinoma in vitro and in vivo
Journal Articles

Abstract 5541: Identification of sod and sod2 as potential prognostic biomarkers for patients with non-small cell lung cancer

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Chen Yin, Ren Wang, Xiao-xing Li, Yang Yang, Mei-yin Zhang, Hui-Yun Wang, Steven X. Zheng
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5541.
https://doi.org/10.1158/1538-7445.AM2017-5541
Published: 01 July 2017
View articletitled, Abstract 5541: Identification of sod and sod2 as potential prognostic biomarkers for patients with non-small cell lung cancer
Journal Articles

Abstract 2545: Upregulated lncRNA-HNGA1, a target of miR-378a, contributes to aerobic glycolysis of head and neck squamous cell carcinoma through increasing levels of the C-C chemokine receptor type 7 (CCR7)

Free
Yun Wang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2545.
https://doi.org/10.1158/1538-7445.AM2017-2545
Published: 01 July 2017
View articletitled, Abstract 2545: Upregulated lncRNA-HNGA1, a target of miR-378a, contributes to aerobic glycolysis of head and neck squamous cell carcinoma through increasing levels of the C-C chemokine receptor type 7 (CCR7)
Journal Articles

Abstract 1407: Translational regulation of RPA2 via IRES by UNR and eIF3a

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Jia-Jia Cui, Lei-Yun Wang, Ji-Ye Yin
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1407.
https://doi.org/10.1158/1538-7445.AM2017-1407
Published: 01 July 2017
View articletitled, Abstract 1407: Translational regulation of RPA2 via IRES by UNR and eIF3a
Journal Articles

EGFL6 Regulates the Asymmetric Division, Maintenance, and Metastasis of ALDH+ Ovarian Cancer Cells

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Shoumei Bai, Patrick Ingram, Yu-Chih Chen, Ning Deng, Alex Pearson, Yashar S. Niknafs, Patrick O'Hayer, Yun Wang, Zhong-Yin Zhang, Elisa Boscolo, Joyce Bischoff, Euisik Yoon, Ronald J. Buckanovich
Journal: Cancer Research
Cancer Res (2016) 76 (21): 6396–6409.
https://doi.org/10.1158/0008-5472.CAN-16-0225
Published: 31 October 2016
View articletitled, EGFL6 Regulates the Asymmetric Division, Maintenance, and Metastasis of ALDH+ Ovarian Cancer Cells
Open the PDF for EGFL6 Regulates the Asymmetric Division, Maintenance, and Metastasis of ALDH+ Ovarian Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 1029: Rab1A and Rab1B promote esophageal squamous cell carcinoma through activating mTORC1 signaling and inhibiting autophagy

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Xian-Zi Yang, Ren Wang, Xiao-Xing Li, Yang Yang, Hui-Yun Wang, X. F. Steven Zheng.
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1029.
https://doi.org/10.1158/1538-7445.AM2016-1029
Published: 15 July 2016
View articletitled, Abstract 1029: Rab1A and Rab1B promote esophageal squamous cell carcinoma through activating mTORC1 signaling and inhibiting autophagy