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Journal Articles

Abstract LB-114: RAF inhibitor LXH254 effectively inhibits B-and-CRAF, but not ARAF

Kelli-Ann Monaco, Scott Delach, Paul Fordjour, Salonee Parikh, Yun Feng, Mariela Jaskelioff, Darrin Stuart, Giordano Caponigro
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-114.
https://doi.org/10.1158/1538-7445.AM2019-LB-114
Published: 01 July 2019
View article titled, Abstract LB-114: RAF inhibitor LXH254 effectively inhibits B-and-CRAF, but not ARAF
Journal Articles

Abstract DDT01-04: Pharmacological profile and anti-tumor properties of LXH254, a highly selective RAF kinase inhibitor

Darrin D. Stuart, Wenlin Shao, Yuji Mishina, Yun Feng, Giordano Caponigro, Vesselina G. Cooke, Stacey Rivera, Fang Shen, Joshua Korn, Lesley A. Mathews Griner, Giselle Nishiguchi, Benjamin Taft, Lifeng Wan, Sharadha Subramanian, Yan Lou, Lina Setti, Matthew Burger, Victor Tamez, Alice Rico, Robert Aversa, John Tellew, Jacob R. Haling, Valery Polyakov, Amy Lambert, Richard Zang, Ann Van Abbema, Mohamad Hekmat-Nejad, Payman Amiri, Mallika Singh, Nicholas Keen, Michael P. Dillon, Emma Lees, William R. Sellers, Savithri Ramurthy
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): DDT01-04.
https://doi.org/10.1158/1538-7445.AM2018-DDT01-04
Published: 01 July 2018
View article titled, Abstract DDT01-04: Pharmacological profile and anti-tumor properties of LXH254, a highly selective RAF kinase inhibitor
Journal Articles

Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF

Wenlin Shao, Yuji M. Mishina, Yun Feng, Giordano Caponigro, Vesselina G. Cooke, Stacy Rivera, Yingyun Wang, Fang Shen, Joshua M. Korn, Lesley A. Mathews Griner, Gisele Nishiguchi, Alice Rico, John Tellew, Jacob R. Haling, Robert Aversa, Valery Polyakov, Richard Zang, Mohammad Hekmat-Nejad, Payman Amiri, Mallika Singh, Nicholas Keen, Michael P. Dillon, Emma Lees, Savithri Ramurthy, William R. Sellers, Darrin D. Stuart
Journal: Cancer Research
Cancer Res (2018) 78 (6): 1537–1548.
https://doi.org/10.1158/0008-5472.CAN-17-2033
Published: 14 March 2018
View article titled, Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF
Open the PDF for Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF in another window
Includes: Supplementary data
Journal Articles

Abstract 1818: Enhanced antitumor and anti-angiogenic effects of Apatinib combined with chemotherapy in a zebrafish model of non-small cell lung cancer

Yi Xiang, Wenchao Zhang, Zhuanbin Wu, Zijun Qian, Jianping Zhou, Xiaofei Wang, Weiqin Wang, Ling Zhou, Jing Liu, Yun Feng, Min Zhou, Guochao Shi, Beili Gao
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1818.
https://doi.org/10.1158/1538-7445.AM2017-1818
Published: 01 July 2017
View article titled, Abstract 1818: Enhanced antitumor and anti-angiogenic effects of Apatinib combined with chemotherapy in a zebrafish model of non-small cell lung cancer
Journal Articles

Abstract 330: Development of a highly selective B/CRAF kinase inhibitor that exhibits antitumor activities in RAS and BRAF mutant tumors with minimal paradoxical activation

Wenlin Shao, Yuji Mishina, Yun Feng, Giordano Caponigro, Savithri Ramurthy, Vesselina Cooke, Lesley Griner, Gisele Nishiguchi, Alice Rico, Ben Taft, Matthew Burger, Huw Tanner, Valery Polyakov, Brent Appleton, John Tellew, Richard Zang, Mohammad Hekmat-Nejad, Payman Amiri, Mallika Singh, Darrin Stuart
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 330.
https://doi.org/10.1158/1538-7445.AM2016-330
Published: 15 July 2016
View article titled, Abstract 330: Development of a highly selective B/CRAF kinase inhibitor that exhibits antitumor activities in RAS and BRAF mutant tumors with minimal paradoxical activation
Journal Articles

Abstract LB-34: Investigating novel biological functions of tankyrases in cancer

Marie Schoumacher, Yun Feng, Yuji Mishina, Wenlin Shao
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-34.
https://doi.org/10.1158/1538-7445.AM2012-LB-34
Published: 15 April 2012
View article titled, Abstract LB-34: Investigating novel biological functions of tankyrases in cancer
Journal Articles

Potent anticancer activity of a pan-deacetylase inhibitor panobinostat (LBH589) as a single agent in in vitro and in vivo tumor models

Wenlin Shao, Joseph Growney, Yun Feng, Ping Wang, Yan Yan-Neale, Gregory O'Connor, Paul Kwon, Yung-mae Yao, Stephen Fawell, Peter Atadja
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 735.
Published: 01 May 2008
View article titled, Potent anticancer activity of a pan-deacetylase inhibitor panobinostat (LBH589) as a single agent in <em>in vitro</em> and <em>in vivo</em> tumor models
Journal Articles

Potent anticancer activity of the deacetylase inhibitor panobinostat (LBH589) in colon cancer cell lines and patient-derived primary colon cancer xenografts

Youzhen Wang, Joseph Growney, Jane Cheng, Colleen Kowal, Guizhi Yang, Rebecca Mosher, Ronald Meyer, Yan Yan-Neale, Minying Pu, Wenlin Shao, Yun Feng, Paul Kwon, Peter Atadja, Stephen Fawell, Yung-mae Yao
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2442.
Published: 01 May 2008
View article titled, Potent anticancer activity of the deacetylase inhibitor panobinostat (LBH589) in colon cancer cell lines and patient-derived primary colon cancer xenografts
Journal Articles

ROS Fusion Tyrosine Kinase Activates a SH2 Domain–Containing Phosphatase-2/Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Signaling Axis to Form Glioblastoma in Mice

Al Charest, Erik W. Wilker, Margaret E. McLaughlin, Keara Lane, Ram Gowda, Shanie Coven, Kevin McMahon, Steven Kovach, Yun Feng, Michael B. Yaffe, Tyler Jacks, David Housman
Journal: Cancer Research
Cancer Res (2006) 66 (15): 7473–7481.
https://doi.org/10.1158/0008-5472.CAN-06-1193
Published: 02 August 2006
View article titled, ROS Fusion Tyrosine Kinase Activates a SH2 Domain–Containing Phosphatase-2/Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Signaling Axis to Form Glioblastoma in Mice
Open the PDF for ROS Fusion Tyrosine Kinase Activates a SH2 Domain–Containing Phosphatase-2/Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Signaling Axis to Form Glioblastoma in Mice in another window
Includes: Supplementary data
Journal Articles

Expression Profiling Identifies a Novel α-Methylacyl-CoA Racemase Exon with Fumarate Hydratase Homology

Grace L. Shen-Ong, Yun Feng, Dean A. Troyer
Journal: Cancer Research
Cancer Res (2003) 63 (12): 3296–3301.
Published: 15 June 2003
View article titled, Expression Profiling Identifies a Novel α-Methylacyl-CoA Racemase Exon with Fumarate Hydratase Homology
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Includes: Supplementary data
Journal Articles

Receptor Binding of Human Granulocyte Colony-stimulating Factor to the Blast Cells of Myeloid Leukemia

Yun-Feng Piao, Tetsuro Okabe
Journal: Cancer Research
Cancer Res (1990) 50 (6): 1671–1674.
Published: 01 March 1990
View article titled, Receptor Binding of Human Granulocyte Colony-stimulating Factor to the Blast Cells of Myeloid Leukemia
Open the PDF for Receptor Binding of Human Granulocyte Colony-stimulating Factor to the Blast Cells of Myeloid Leukemia in another window