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Yuichiro Doki
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Journal Articles

Abstract 5855: Spatial transcriptomics deciphers the cellular society of advanced colorectal cancer

Masahiro Hashimoto, Yuki Ozato, Yusuke Nakano, Tadashi Abe, Yuichi Hisamastu, Takeo Toshima, Yusuke Yonemura, Mamoru Uemura, Takaaki Masuda, Hirofumi Yamamoto, Masaki Mori, Hidetoshi Eguchi, Yuichiro Doki, Koshi Mimori
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5855.
https://doi.org/10.1158/1538-7445.AM2023-5855
Published: 04 April 2023
View article titled, Abstract 5855: Spatial transcriptomics deciphers the cellular society of advanced colorectal cancer
Journal Articles

Abstract 101: Convergent genomic diversity and novel oncogenic metabolism in intrahepatic cholangiocarcinoma

Yusuke Nakano, Akihiro Kitagawa, Masahiro Hashimoto, Tadashi Abe, Yuichi Hisamatsu, Takeo Toshima, Yusuke Yonemura, Takaaki Masuda, Akira Inoue, Hidetoshi Eguchi, Yuichiro Doki, Koshi Mimori
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 101.
https://doi.org/10.1158/1538-7445.AM2023-101
Published: 04 April 2023
View article titled, Abstract 101: Convergent genomic diversity and novel oncogenic metabolism in intrahepatic cholangiocarcinoma
Journal Articles

Abstract 892: Single-cell RNA sequencing of patient-derived organoid reveals treatment-induced tumor resistance through cancer stem cells

Shiki Fujino, Aya Ito, Masayoshi Yasui, Chu Matsuda, Masayuki Ohue, Masafumi Horie, Shinichi Yachida, Yuichiro Doki, Hidetoshi Eguchi, Norikatsu Miyoshi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 892.
https://doi.org/10.1158/1538-7445.AM2022-892
Published: 15 June 2022
View article titled, Abstract 892: Single-cell RNA sequencing of patient-derived organoid reveals treatment-induced tumor resistance through cancer stem cells
Journal Articles

Abstract 2630: Heterogeneity inducible tumor stem cells relate distant metastasis and the treatment resistance

Norikatsu Miyoshi, Shiki Fujino, Yuki Sekido, Tsuyoshi Hata, Takayuki Ogino, Hidekazu Takahashi, Mamoru Uemura, HIrofumi Yamamoto, Yuichiro Doki, Hidetoshi Eguchi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2630.
https://doi.org/10.1158/1538-7445.AM2022-2630
Published: 15 June 2022
View article titled, Abstract 2630: Heterogeneity inducible tumor stem cells relate distant metastasis and the treatment resistance
Journal Articles

Abstract 6170: Newly emerging CD44 negative cells after irradiation reproduce CD44 positive cells and promote radioresistance

Masaru Sasaki, Norikatsu Miyoshi, Shiki Fujino, Takayuki Ogino, Hidekazu Takahashi, Mamoru Uemura, Chu Matsuda, Hirofumi Yamamoto, Tsunekazu Mizushima, Masaki Mori, Yuichiro Doki
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6170.
https://doi.org/10.1158/1538-7445.AM2020-6170
Published: 15 August 2020
View article titled, Abstract 6170: Newly emerging CD44 negative cells after irradiation reproduce CD44 positive cells and promote radioresistance
Journal Articles

Abstract 4962: Tumor heterogeneity driven by cancer stem cell expressing POU5F1

Norikatsu Miyoshi, Shiki Fujino, Masaru Sasaki, Takayuki Ogino, Hidekazu Takahashi, Mamoru Uemura, Chu Matsuda, Tsunekazu Mizushima, Hidetoshi Eguchi, Yuichiro Doki
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4962.
https://doi.org/10.1158/1538-7445.AM2020-4962
Published: 15 August 2020
View article titled, Abstract 4962: Tumor heterogeneity driven by cancer stem cell expressing POU5F1
Journal Articles

Abstract 5266: Continuous trifluridine treatment in colorectal cancer cell lines- investigating its potential

Kenta Tsunekuni, Kazuaki Matsuoka, Takashi Kobunai, Teiji Takechi, Hidetoshi Eguchi, Masaki Mori, Yuichiro Doki, Hideshi Ishii
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5266.
https://doi.org/10.1158/1538-7445.AM2020-5266
Published: 15 August 2020
View article titled, Abstract 5266: Continuous trifluridine treatment in colorectal cancer cell lines- investigating its potential
Journal Articles

Abstract 1535: Identification of novel epithelial-mesenchymal transition inducers and their clinical significance in colorectal cancer

Satoshi Ishikawa, Naohiro Nishida, Shiki Fujino, Takayuki Ogino, Hidekazu Takahashi, Norikatsu Miyoshi, Mamoru Uemura, Chu Matsuda, Tsunekazu Mizusima, Hirofumi Yamamoto, Koshi Mimori, Masaki Mori, Yuichiro Doki, Hidedoshi Eguchi
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1535.
https://doi.org/10.1158/1538-7445.AM2020-1535
Published: 15 August 2020
View article titled, Abstract 1535: Identification of novel epithelial-mesenchymal transition inducers and their clinical significance in colorectal cancer
Journal Articles

Abstract 2150: CD103+ tumor infiltrating lymphocytes predict a favorable prognosis in human colorectal cancer

Masatoshi Kitakaze, Masamitsu Konno, Taroh Satoh, Tsunekazu Mizushima, Yuichiro Doki, Hideshi Ishii
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2150.
https://doi.org/10.1158/1538-7445.AM2020-2150
Published: 15 August 2020
View article titled, Abstract 2150: CD103+ tumor infiltrating lymphocytes predict a favorable prognosis in human colorectal cancer
Journal Articles

Abstract 264: Long noncoding RNA LNC01534 regulates cancer stem cells in colorectal cancer

Masahisa Ohtsuka, Wu Xin, Momoko Ichihara, Haruka Hirose, Hidekazu Takahashi, Chu Matsuda, Hiroki Akamatsu, Tsunekazu Mizushima, Yuichiro Doki, Hirofumi Yamamoto
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 264.
https://doi.org/10.1158/1538-7445.AM2020-264
Published: 15 August 2020
View article titled, Abstract 264: Long noncoding RNA LNC01534 regulates cancer stem cells in colorectal cancer
Journal Articles

Abstract 4000: PDGFR is a key factor to regulate stemness and epithelial mesenchymal transition of colorectal cancer with suppression of tumor microenvironment

Shiki Fujino, Norikatsu Miyoshi, Aya Ito, Masaru Sasaki, Takasyuki Ogino, Hidekazu Takahashi, Mamoru Uemura, Chu Matsuda, Tsunekazu Mizushima, Yuichiro Doki
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4000.
https://doi.org/10.1158/1538-7445.AM2020-4000
Published: 15 August 2020
View article titled, Abstract 4000: PDGFR is a key factor to regulate stemness and epithelial mesenchymal transition of colorectal cancer with suppression of tumor microenvironment
Journal Articles

Abstract 108: Efficiency improvement niche factors in drug susceptibility test using two dimension organoids derived from colorectal cancer

Kazuhiro Saso, Norikatsu Miyoshi, Masaru Sasaki, Shiki Fujino, Hidekazu Takahashi, Naotsugu Haraguchi, Taishi Hata, Chu Matsuda, Tsunekazu Mizushima, Masaki Mori, Yuichiro Doki
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 108.
https://doi.org/10.1158/1538-7445.AM2019-108
Published: 01 July 2019
View article titled, Abstract 108: Efficiency improvement niche factors in drug susceptibility test using two dimension organoids derived from colorectal cancer
Journal Articles

Abstract 2963: CD44+/CD133+ colorectal cancer stem cells are sensitive to trifluridine

Kenta Tsunekuni, Masamitsu Konno, Jun Koseki, Ayumu Asai, Kazuaki Matsuoka, Teiji Takechi, Yuichiro Doki, Masaki Mori, Hideshi Ishii
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2963.
https://doi.org/10.1158/1538-7445.AM2019-2963
Published: 01 July 2019
View article titled, Abstract 2963: CD44<sup>+</sup>/CD133<sup>+</sup> colorectal cancer stem cells are sensitive to trifluridine
Journal Articles

Abstract 1519: The impact of ICOS+ Tregs on prognosis of gastric cancer patients

Shinya Urakawa, Hisashi Wada, Masaki Mori, Yuichiro Doki
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1519.
https://doi.org/10.1158/1538-7445.AM2019-1519
Published: 01 July 2019
View article titled, Abstract 1519: The impact of ICOS+ Tregs on prognosis of gastric cancer patients
Journal Articles

Abstract 1578: Cohesin complex-related genes in colorectal cancer

Masaru Sasaki, Norikatsu Miyoshi, Kazuhiro Saso, Shiki Fujino, Hidekazu Takahashi, Naotsugu Haraguchi, Chu Matsuda, Taishi Hata, Hirofumi Yamamoto, Tsunekazu Mizushima, Masaki Mori, Yuichiro Doki
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1578.
https://doi.org/10.1158/1538-7445.AM2019-1578
Published: 01 July 2019
View article titled, Abstract 1578: Cohesin complex-related genes in colorectal cancer
Journal Articles

Abstract 3687: Colorectal cancer stem cell expressing POU5F1 promotes liver metastasis

Norikatsu Miyoshi, Shiki Fujino, Masaru Sasaki, Kazuhiro Saso, Hidekazu Takahashi, Naotsugu Haraguchi, Taishi Hata, Chu Matsuda, Tsunekazu Mizushima, Masaki Mori, Yuichiro Doki
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3687.
https://doi.org/10.1158/1538-7445.AM2019-3687
Published: 01 July 2019
View article titled, Abstract 3687: Colorectal cancer stem cell expressing POU5F1 promotes liver metastasis
Journal Articles

Abstract 3707: 2D organoid (2DO) as human tumor model for predicting therapeutic effect of anti-cancer drugs

Shiki Fujino, Norikatsu Miyoshi, Kazuhiro Saso, Masaru Sasaki, Masayoshi Yasui, Masayuki Ohue, HIdekazu Takahashi, Naotsugu Haraguchi, Chu Matsuda, Taishi Hata, Tsunekazu Mizushima, Masaki Mori, Yuichiro Doki
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3707.
https://doi.org/10.1158/1538-7445.AM2019-3707
Published: 01 July 2019
View article titled, Abstract 3707: 2D organoid (2DO) as human tumor model for predicting therapeutic effect of anti-cancer drugs
Journal Articles

Disruption of Endolysosomal RAB5/7 Efficiently Eliminates Colorectal Cancer Stem Cells

Mitsunobu Takeda, Jun Koseki, Hidekazu Takahashi, Norikatsu Miyoshi, Naohiro Nishida, Junichi Nishimura, Taishi Hata, Chu Matsuda, Tsunekazu Mizushima, Hirofumi Yamamoto, Hideshi Ishii, Yuichiro Doki, Masaki Mori, Naotsugu Haraguchi
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (7): 1426–1437.
https://doi.org/10.1158/0008-5472.CAN-18-2192
Published: 01 April 2019
View article titled, Disruption of Endolysosomal RAB5/7 Efficiently Eliminates Colorectal Cancer Stem Cells
Open the PDF for Disruption of Endolysosomal RAB5/7 Efficiently Eliminates Colorectal Cancer Stem Cells in another window
Includes: Supplementary data
Journal Articles

A Convolutional Neural Network Uses Microscopic Images to Differentiate between Mouse and Human Cell Lines and Their Radioresistant Clones

Masayasu Toratani, Masamitsu Konno, Ayumu Asai, Jun Koseki, Koichi Kawamoto, Keisuke Tamari, Zhihao Li, Daisuke Sakai, Toshihiro Kudo, Taroh Satoh, Katsutoshi Sato, Daisuke Motooka, Daisuke Okuzaki, Yuichiro Doki, Masaki Mori, Kazuhiko Ogawa, Hideshi Ishii
Journal: Cancer Research
Cancer Res (2018) 78 (23): 6703–6707.
https://doi.org/10.1158/0008-5472.CAN-18-0653
Published: 03 December 2018
View article titled, A Convolutional Neural Network Uses Microscopic Images to Differentiate between Mouse and Human Cell Lines and Their Radioresistant Clones
Open the PDF for A Convolutional Neural Network Uses Microscopic Images to Differentiate between Mouse and Human Cell Lines and Their Radioresistant Clones in another window
Includes: Supplementary data
Journal Articles

p63-Dependent Dickkopf3 Expression Promotes Esophageal Cancer Cell Proliferation via CKAP4

Chihiro Kajiwara, Katsumi Fumoto, Hirokazu Kimura, Satoshi Nojima, Keita Asano, Kazuki Odagiri, Makoto Yamasaki, Hayato Hikita, Tetsuo Takehara, Yuichiro Doki, Eiichi Morii, Akira Kikuchi
Journal: Cancer Research
Cancer Res (2018) 78 (21): 6107–6120.
https://doi.org/10.1158/0008-5472.CAN-18-1749
Published: 01 November 2018
View article titled, p63-Dependent Dickkopf3 Expression Promotes Esophageal Cancer Cell Proliferation via CKAP4
Open the PDF for p63-Dependent Dickkopf3 Expression Promotes Esophageal Cancer Cell Proliferation via CKAP4 in another window
Includes: Supplementary data