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Journal Articles

MEN1 Degradation Induced by Neddylation and the CUL4B–DCAF7 Axis Promotes Pancreatic Neuroendocrine Tumor Progression

Junfeng Xu, Zeng Ye, Qifeng Zhuo, Heli Gao, Yi Qin, Xin Lou, Wuhu Zhang, Fei Wang, Yan Wang, Desheng Jing, Guixiong Fan, Yue Zhang, Xuemin Chen, Jie Chen, Xiaowu Xu, Xianjun Yu, Shunrong Ji
Journal: Cancer Research
Cancer Res (2023) 83 (13): 2226–2247.
https://doi.org/10.1158/0008-5472.CAN-22-3599
Published: 05 July 2023
View article titled, MEN1 Degradation Induced by Neddylation and the CUL4B–DCAF7 Axis Promotes Pancreatic Neuroendocrine Tumor Progression
Open the PDF for MEN1 Degradation Induced by Neddylation and the CUL4B–DCAF7 Axis Promotes Pancreatic Neuroendocrine Tumor Progression in another window
Includes: Supplementary data
Journal Articles

Abstract 1020: Tissue-informed ctDNA MRD assay detects post-surgery minimal residual disease in HCC patients

Jie Hu, Haoran Tang, Feng Xie, Yue Zhang, Shidong Jia, Jian Zhou
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1020.
https://doi.org/10.1158/1538-7445.AM2023-1020
Published: 04 April 2023
View article titled, Abstract 1020: Tissue-informed ctDNA MRD assay detects post-surgery minimal residual disease in HCC patients
Journal Articles

Abstract 2936: INCA33890, a novel PD-1×TGFꞵR2 bispecific antibody conditionally antagonizes TGFꞵ signaling in primary immune cells co-expressing PD-1

Liang-Chuan S. Wang, Rinse Klooster, Ashwini Kulkarni, Amaya Garcia de Vinuesa, Maxim Soloviev, Linda JA Hendriks, Lu Huo, Michael Weber, Arpita Mondal, Yonghong Zhao, Shane Harvey, Xin He, Hong Chang, April Horsey, Alla Volgina, Yue Zhang, Veethika Pandey, Yan-Ou Yang, Jonathan Rios-Doria, Evgeniy Eruslanov, Daniel J. Powell, Steven M. Albelda, John de Kruif, Horacio Nastri, Cecile Geuijen, Patrick A. Mayes
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2936.
https://doi.org/10.1158/1538-7445.AM2023-2936
Published: 04 April 2023
View article titled, Abstract 2936: INCA33890, a novel PD-1×TGFꞵR2 bispecific antibody conditionally antagonizes TGFꞵ signaling in primary immune cells co-expressing PD-1
Journal Articles

Abstract 4745: Prostatic fluid-based cfDNA methylation profiling distinguish benign hyperplasia from prostate cancer

Hang Dong, Haoran Tang, Yue Zhang, Shidong Jia
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4745.
https://doi.org/10.1158/1538-7445.AM2023-4745
Published: 04 April 2023
View article titled, Abstract 4745: Prostatic fluid-based cfDNA methylation profiling distinguish benign hyperplasia from prostate cancer
Journal Articles

Abstract 5582: Liquid biopsy-based comprehensive genomic profiling reveal mutational landscape in real-world patients with unresectable NSCLC

Haoran Tang, Feng Xie, Yue Zhang, Shidong Jia
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5582.
https://doi.org/10.1158/1538-7445.AM2023-5582
Published: 04 April 2023
View article titled, Abstract 5582: Liquid biopsy-based comprehensive genomic profiling reveal mutational landscape in real-world patients with unresectable NSCLC
Journal Articles

Abstract 1049: Liquid biopsy-based comprehensive genomic profiling reveal mutational landscape in advanced breast cancer

Haoran Tang, Feng Xie, Yue Zhang, Shidong Jia
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1049.
https://doi.org/10.1158/1538-7445.AM2023-1049
Published: 04 April 2023
View article titled, Abstract 1049: Liquid biopsy-based comprehensive genomic profiling reveal mutational landscape in advanced breast cancer
Journal Articles

Abstract 2197: Comparative genomic profiling and disease monitoring in unresectable gastric and colon cancer

Haoran Tang, Feng Xie, Yue Zhang, Shidong Jia
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2197.
https://doi.org/10.1158/1538-7445.AM2023-2197
Published: 04 April 2023
View article titled, Abstract 2197: Comparative genomic profiling and disease monitoring in unresectable gastric and colon cancer
Journal Articles

Abstract 2752: Targeting intracellular tumor antigens using fully human TCR mimic antibodies derived from HLA transgenic RenMiceTM

Jun Du, Taolin Liu, Wanbo Tang, Yue Zhang, Limin Zhao, Xin Jiao, Chao Sun, Pengfei Du, Yuqi Zhang, Baihong Liu, Qingcong Lin, Yi Yang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2752.
https://doi.org/10.1158/1538-7445.AM2023-2752
Published: 04 April 2023
View article titled, Abstract 2752: Targeting intracellular tumor antigens using fully human TCR mimic antibodies derived from HLA transgenic RenMice<sup>TM</sup>
Journal Articles

Abstract PD11-10: PD11-10 Efficacy, Safety, and Tolerability of KN046 (an anti-PD-L1/CTLA-4 Bispecific Antibody) in combination with Nab-paclitaxel in Metastatic Triple-negative Breast Cancer (mTNBC):Final results of the Phase II trial

Qiao Li, Qingyuan Zhang, Yue Zhang, Quchang Ouyang, Qiang Liu, Tao Sun, Feng Ye, Baochun Zhang, Ting Xu, Summer Xia, Karl Zhang, Bangyong Zhang, Binghe Xu
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): PD11-10.
https://doi.org/10.1158/1538-7445.SABCS22-PD11-10
Published: 01 March 2023
View article titled, Abstract PD11-10: PD11-10 Efficacy, Safety, and Tolerability of KN046 (an anti-PD-L1/CTLA-4 Bispecific Antibody) in combination with Nab-paclitaxel in Metastatic Triple-negative Breast Cancer (mTNBC):Final results of the Phase II trial
Journal Articles

Abstract 5315: Anti-tumor activity of KRASG12C inhibitors is enhanced when combined with Cdc42 effector p21-activated kinase 4 targeting agents

Husain Yar Khan, Sahar Bannoura, Hirva Mamdani, Amro Aboukameel, Yousef Mzannar, Yiwei Li, Mohammad Najeeb Al-Hallak, Ibrahim Azar, Steve Kim, Rafic Beydoun, Ramzi Mohammad, Yosef Landesman, Yue Zhang, Erkan Baloglu, William Senapedis, Ammar Sukari, Misako Nagasaka, Anthony Shields, Asfar S. Azmi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5315.
https://doi.org/10.1158/1538-7445.AM2022-5315
Published: 15 June 2022
View article titled, Abstract 5315: Anti-tumor activity of KRAS<sup>G12C</sup> inhibitors is enhanced when combined with Cdc42 effector p21-activated kinase 4 targeting agents
Journal Articles

Abstract 579: Anti-myeloid poly-pharmacy allows FGFR4-targeted chimeric antigen receptors to effectively treat an orthotopic model of rhabdomyosarcoma

Peter M. Sullivan, Rajesh Kumar, Wei Li, Lingyang Wang, Yue Zhang, Sophie Jamet, Adam Cheuk, Javed Khan, Dimiter S. Dimitrov, Rimas J. Orentas
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 579.
https://doi.org/10.1158/1538-7445.AM2022-579
Published: 15 June 2022
View article titled, Abstract 579: Anti-myeloid poly-pharmacy allows FGFR4-targeted chimeric antigen receptors to effectively treat an orthotopic model of rhabdomyosarcoma
Journal Articles

Thymosin α-1 Reverses M2 Polarization of Tumor-Associated Macrophages during Efferocytosis

Yi-ting Wei, Xu-ru Wang, Chunguang Yan, Fang Huang, Yunpeng Zhang, Xueming Liu, Zhi-fa Wen, Xiao-tong Sun, Yue Zhang, Yong-qiang Chen, Rong Gao, Ning Pan, Li-xin Wang
Journal: Cancer Research
Cancer Res (2022) 82 (10): 1991–2002.
https://doi.org/10.1158/0008-5472.CAN-21-4260
Published: 16 May 2022
View article titled, Thymosin α-1 Reverses M2 Polarization of Tumor-Associated Macrophages during Efferocytosis
Open the PDF for Thymosin α-1 Reverses M2 Polarization of Tumor-Associated Macrophages during Efferocytosis in another window
Includes: Supplementary data
Journal Articles

Abstract GS1-06: A randomized control phase III trial of entinostat, a once weekly, class I selective histone deacetylase inhibitor, in combination with exemestane in patients with hormone receptor positive advanced breast cancer

Binghe Xu, Qingyuan Zhang, Xichun Hu, Qing Li, Tao Sun, Wei Li, Quchang Ouyang, Jingfen Wang, Zhongsheng Tong, Min Yan, Huiping Li, Xiaohua Zeng, Changping Shan, Xian Wang, Xi Yan, Jian Zhang, Yue Zhang, Jiani Wang, Liang Zhang, Ying Lin, Jifeng Feng, Qianjun Chen, Jian Huang, Yongkui Lu, Hongsheng Li, Jinsheng Wu, Jing Cheng, Yanrong Hao, Cuizhi Geng, Min Lu, Yanping Li, Xi Chen, Lihua Song, Xueying Wu, Changlu Hu, Xinhong Wu, Xiaojia Wang, Yueyin Pan, Yuehong Cui, Guohua Yu, Sanyuan Sun
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): GS1-06.
https://doi.org/10.1158/1538-7445.SABCS21-GS1-06
Published: 15 February 2022
View article titled, Abstract GS1-06: A randomized control phase III trial of entinostat, a once weekly, class I selective histone deacetylase inhibitor, in combination with exemestane in patients with hormone receptor positive advanced breast cancer
Journal Articles

Abstract 1058: Inhibition of nuclear transport protein XPO1 potentiates the effect of KRASG12C inhibitors

Husain Y. Khan, Md. Hafiz Uddin, Yue Zhang, Yosef Landesman, Ammar Sukari, Misako Nagasaka, Asfar S. Azmi
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1058.
https://doi.org/10.1158/1538-7445.AM2021-1058
Published: 01 July 2021
View article titled, Abstract 1058: Inhibition of nuclear transport protein XPO1 potentiates the effect of KRAS<sup>G12C</sup> inhibitors
Journal Articles

Abstract 1546: Defining the immune microenvironment in Ewing's sarcoma to potentiate IL1RAP-targeted CAR-T immunotherapy

Rajesh Kumar, Peter Sullivan, Wei Li, Haifeng Zhang, Virginia Hoglund, Lingyang Wang, Yue Zhang, Poul H. Sorensen, Dimiter S. Dimitrov, Rimas J. Orentas
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1546.
https://doi.org/10.1158/1538-7445.AM2021-1546
Published: 01 July 2021
View article titled, Abstract 1546: Defining the immune microenvironment in Ewing's sarcoma to potentiate IL1RAP-targeted CAR-T immunotherapy
Journal Articles

Abstract 1545: Development of FGFR4-targeted chimeric antigen receptors (CARs) for the treatment of rhabdomyosarcoma

Peter Sullivan, Rajesh Kumar, Wei Li, Lingyang Wang, Yue Zhang, Adam Cheuk, Nityashree Shivaprasad, Javed Khan, Dimiter S. Dimitrov, Rimas J. Orentas
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1545.
https://doi.org/10.1158/1538-7445.AM2021-1545
Published: 01 July 2021
View article titled, Abstract 1545: Development of FGFR4-targeted chimeric antigen receptors (CARs) for the treatment of rhabdomyosarcoma
Journal Articles

Abstract 1660: Preliminary safety tolerability & efficacy results of KN046 (an anti-PD-L1/CTLA-4 bispecific antibody) in combination with Nab-paclitaxel in patients with metastatic triple-negative breast cancer (mTNBC)

Binghe Xu, Qiao Li, Qingyuan Zhang, Yue Zhang, Quchang Ouyang, Yang Zhang, Qiang Liu, Tao Sun, June Xu, Jing Yang, Yue Yang, Xin Luo, Paul Kong, Ting Xu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1660.
https://doi.org/10.1158/1538-7445.AM2021-1660
Published: 01 July 2021
View article titled, Abstract 1660: Preliminary safety tolerability &amp; efficacy results of KN046 (an anti-PD-L1/CTLA-4 bispecific antibody) in combination with Nab-paclitaxel in patients with metastatic triple-negative breast cancer (mTNBC)
Journal Articles

Abstract 2138: Whole genome cfDNA profiles reveal common signatures of Immune checkpoint inhibition response in kidney, melanoma, and lung cancers

Hayley Donnella, Yue Zhang, Irving Wang, Francesco Vallania, Maggie Louie, C. Jimmy Lin
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2138.
https://doi.org/10.1158/1538-7445.AM2021-2138
Published: 01 July 2021
View article titled, Abstract 2138: Whole genome cfDNA profiles reveal common signatures of Immune checkpoint inhibition response in kidney, melanoma, and lung cancers
Journal Articles

Abstract PS16-08: Germline mutation landscape in Chinese breast cancer patients

Nan Wang, Jiayang Zhang, Lu Tan, Hao Liao, Yaxin Liu, Xinyu Gui, Jiaxin Niu, Feng Xie, Yue Zhang, Yong Huang, Jianjun Yu, Huiping Li
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS16-08.
https://doi.org/10.1158/1538-7445.SABCS20-PS16-08
Published: 15 February 2021
View article titled, Abstract PS16-08: Germline mutation landscape in Chinese breast cancer patients
Journal Articles

Abstract PS2-25: Cell-free DNA based detection of mono-allelic versus bi-allelic loss of function for essential genes in breast cancer

Feng Xie, Haoran Tang, Yue Zhang, Yong Huang
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS2-25.
https://doi.org/10.1158/1538-7445.SABCS20-PS2-25
Published: 15 February 2021
View article titled, Abstract PS2-25: Cell-free DNA based detection of mono-allelic versus bi-allelic loss of function for essential genes in breast cancer