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Journal Articles

Abstract 1515: Tertiary lymphoid structures restrain cancer evolution by supporting stem-like CD8+ T cells for sustained anti-tumor immunity

Pengxiang Wang, Chi Zhou, Zhiting Wei, Yue Wang, Yuli Gao, Fangliangzi Meng, Jian Zhou, Jia Fan, Qi Liu, Yunfan Sun
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1515.
https://doi.org/10.1158/1538-7445.AM2024-1515
Published: 22 March 2024
View article titled, Abstract 1515: Tertiary lymphoid structures restrain cancer evolution by supporting stem-like CD8+ T cells for sustained anti-tumor immunity
Journal Articles

Abstract 6726: Costimulatory IgM T-cell engagers with enhanced and durable cytotoxicity

Jie Xue, Keyu Li, Poonam Yakkundi, Palak Chadasama, Tina Mao, Zee Malik, Vidhya Rao, Madhura Joglekar, Kristene Mai, Gene Li, Deepal Pandya, Rodnie Rosete, Zhongde Ye, Leyla Tahrani, Jinqiu Wang, Nardeen Hanna, Elizabeth Perez, Yue Wang, Sachi Ahmed, Lusiana Widjaja, Paul Hinton, Krzysztof Bzymek, Bruce Keyt, Miho Oyasu, Liqin Liu, Angus Sinclair, Umesh S. Muchhal
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6726.
https://doi.org/10.1158/1538-7445.AM2024-6726
Published: 22 March 2024
View article titled, Abstract 6726: Costimulatory IgM T-cell engagers with enhanced and durable cytotoxicity
Journal Articles

Abstract 2282: Predictive association of tumor cells hijacked NFATC2 activities with resistance to immune checkpoint inhibition in melanoma patients

Bashir Lawal, Yue Wang, Parisa Lotfinejad, Xiaosong Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2282.
https://doi.org/10.1158/1538-7445.AM2024-2282
Published: 22 March 2024
View article titled, Abstract 2282: Predictive association of tumor cells hijacked NFATC2 activities with resistance to immune checkpoint inhibition in melanoma patients
Journal Articles

Abstract 5155: CD8+ T cells and CD4+central memory T cells as biomarkers of perioperative anti-PD-1 therapy in combination with concurrent chemoradiotherapy for locally advanced G/GEJ adenocarcinoma

Yue Wang, Yawei Chen, Ju Yang, Xiaoyu Zhou, Yutao Wei, Qin Liu, Yang Yang, Wenxian Guan, Baorui Liu, Jia Wei
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5155.
https://doi.org/10.1158/1538-7445.AM2024-5155
Published: 22 March 2024
View article titled, Abstract 5155: CD8<sup>+</sup> T cells and CD4<sup>+</sup>central memory T cells as biomarkers of perioperative anti-PD-1 therapy in combination with concurrent chemoradiotherapy for locally advanced G/GEJ adenocarcinoma
Journal Articles

Abstract 162: Fatty acid synthesis blockade synergizes with immune checkpoint blockade by repolarizing macrophages and enhancing anti-tumor cytotoxicity in gastric cancer

Hanbing Wang, Tao Shi, Yue Wang, Yuting Luo, Yunfeng Pan, Xiaoyu Zhou, Yue Zhang, Baorui Liu, Jia Wei
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 162.
https://doi.org/10.1158/1538-7445.AM2024-162
Published: 22 March 2024
View article titled, Abstract 162: Fatty acid synthesis blockade synergizes with immune checkpoint blockade by repolarizing macrophages and enhancing anti-tumor cytotoxicity in gastric cancer
Journal Articles

Abstract B034: Order-of-mutation effects on cancer progression: Models for myeloproliferative neoplasm

Yue Wang, Tom Chou, Blerta Shtylla
Journal: Cancer Research
Cancer Res (2024) 84 (3_Supplement_2): B034.
https://doi.org/10.1158/1538-7445.CANEVOL23-B034
Published: 01 February 2024
View article titled, Abstract B034: Order-of-mutation effects on cancer progression: Models for myeloproliferative neoplasm
Journal Articles

DPP9 Stabilizes NRF2 to Suppress Ferroptosis and Induce Sorafenib Resistance in Clear Cell Renal Cell Carcinoma

Kun Chang, Yingji Chen, Xuanzhi Zhang, Wei Zhang, Ning Xu, Bohan Zeng, Yue Wang, Tao Feng, Bo Dai, Fujiang Xu, Dingwei Ye, Chenji Wang
Journal: Cancer Research
Cancer Res (2023) 83 (23): 3940–3955.
https://doi.org/10.1158/0008-5472.CAN-22-4001
Published: 01 December 2023
View article titled, DPP9 Stabilizes NRF2 to Suppress Ferroptosis and Induce Sorafenib Resistance in Clear Cell Renal Cell Carcinoma
Open the PDF for DPP9 Stabilizes NRF2 to Suppress Ferroptosis and Induce Sorafenib Resistance in Clear Cell Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

TONSL Is an Immortalizing Oncogene and a Therapeutic Target in Breast Cancer

Aditi S. Khatpe, Rebecca Dirks, Poornima Bhat-Nakshatri, Henry Mang, Katie Batic, Sarah Swiezy, Jacob Olson, Xi Rao, Yue Wang, Hiromi Tanaka, Sheng Liu, Jun Wan, Duojiao Chen, Yunlong Liu, Fang Fang, Sandra Althouse, Emily Hulsey, Maggie M. Granatir, Rebekah Addison, Constance J. Temm, George Sandusky, Audrey Lee-Gosselin, Kenneth Nephew, Kathy D. Miller, Harikrishna Nakshatri
Journal: Cancer Research
Cancer Res (2023) 83 (8): 1345–1360.
https://doi.org/10.1158/0008-5472.CAN-22-3667
Published: 14 April 2023
View article titled, TONSL Is an Immortalizing Oncogene and a Therapeutic Target in Breast Cancer
Open the PDF for TONSL Is an Immortalizing Oncogene and a Therapeutic Target in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 5458: TONSL is an immortalizing oncogene of the chromosome 8q24.3 amplicon and new therapeutic target in breast cancer

Aditi S. Khatpe, Rebecca Dirks, Poornima Bhat-Nakshatri, Henry Mang, Katie Batic, Sarah Swiezy, Jacob Olson, Xi Rao, Yue Wang, Hiromi Tanaka, Sheng Liu, Jun Wan, Duojiao Chen, Yunlong Liu, Fang Fang, Sandra Althouse, Emily Hilsey, Maggie M. Granatir, Rebekah Addison, Constance J. Temm, George Sandusky, Audrey Lee-Gosselin, Kenneth Nephew Nephew, Kathy D. Miller, Harikrishna Nakshatri
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5458.
https://doi.org/10.1158/1538-7445.AM2023-5458
Published: 04 April 2023
View article titled, Abstract 5458: TONSL is an immortalizing oncogene of the chromosome 8q24.3 amplicon and new therapeutic target in breast cancer
Journal Articles

Abstract 296: Antigen-independent delivery of 4-1BB agonist to the tumor microenvironment improves immune response while reducing hepatotoxicity

Hyesun Hyun, Bo Sun, Stephanie A. Montgomery, Teresa Griffin, Juanzhu Yan, Albert Wielgus, Yue Wang, Tian Zhang, Jianjun Cheng, Andrew Z. Wang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 296.
https://doi.org/10.1158/1538-7445.AM2022-296
Published: 15 June 2022
View article titled, Abstract 296: Antigen-independent delivery of 4-1BB agonist to the tumor microenvironment improves immune response while reducing hepatotoxicity
Journal Articles

Abstract 5594: Systematic identification of the chemo-immunotherapy synergism to overcome immunotherapy resistance in cancer

Yue Wang, Yifei Wang, Xiaofei Wang, Zehua Wang, Min Zhang, Da Yang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5594.
https://doi.org/10.1158/1538-7445.AM2022-5594
Published: 15 June 2022
View article titled, Abstract 5594: Systematic identification of the chemo-immunotherapy synergism to overcome immunotherapy resistance in cancer
Journal Articles

Abstract 6199: Fusion genes: Novel therapeutic targets for gastric signet ring cell carcinoma

Yue Wang, Tao Shi, Xuan Wang, Jinwei Hu, Lixia Yu, Qin Liu, Nandie Wu, Baorui Liu, Jia Wei
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6199.
https://doi.org/10.1158/1538-7445.AM2022-6199
Published: 15 June 2022
View article titled, Abstract 6199: Fusion genes: Novel therapeutic targets for gastric signet ring cell carcinoma
Journal Articles

Abstract 6176: CD56 dim+ immune infiltration and reprogrammed TMEs associated with response to neoadjuvant anti-PD-1 immunotherapy plus concurrent chemoradiotherapy in locally advanced gastric or gastroesophageal junction adenocarcinoma

Jia Wei, Qin Liu, Hui Chen, Xin Zhang, Feilong Zhao, Yao Fu, Ju Yang, Yue Wang, Shiqing Chen, Xiaochen Zhao, Yuezong Bai, Wenxian Guan, Baorui Liu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6176.
https://doi.org/10.1158/1538-7445.AM2022-6176
Published: 15 June 2022
View article titled, Abstract 6176: CD56 dim<sup>+</sup> immune infiltration and reprogrammed TMEs associated with response to neoadjuvant anti-PD-1 immunotherapy plus concurrent chemoradiotherapy in locally advanced gastric or gastroesophageal junction adenocarcinoma
Journal Articles

Abstract P2-12-15: Neoadjuvant liposomal doxorubicin and carboplatin is effective and tolerable for the treatment of early stage triple negative breast cancer

Nancy Chan, Shou-en Lu, Yue Wang, Gregory M Riedlinger, Coral Omene, Mridula George, Jyoti Malhotra, Maria Kowzun, Firas G Eladoumikdachi, Lindsay B Potdevin, Shicha Kumar, Kant Matsuda, Shruti Desai, Nayana Patel, Deborah L Toppmeyer, Shridar Ganesan, Kim Hirshfield
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-12-15.
https://doi.org/10.1158/1538-7445.SABCS21-P2-12-15
Published: 15 February 2022
View article titled, Abstract P2-12-15: Neoadjuvant liposomal doxorubicin and carboplatin is effective and tolerable for the treatment of early stage triple negative breast cancer
Journal Articles

Abstract OT1-17-02: A phase II study of pembrolizumab plus fulvestrant in hormone receptor positive, HER-2 negative advanced/metastatic breast cancer patients

Nancy Chan, Dirk Moore, Pavankumar Tandra, Jatin Rana, Coral Omene, Mridula George, Jairam Krishnamurthy, Shruti Desai, Nayana Patel, Yue Wang, Marc Bicomong, Xiao-wei Tan, Kim Hirshfield, Shridar Ganesan, Deborah Toppmeyer
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): OT1-17-02.
https://doi.org/10.1158/1538-7445.SABCS21-OT1-17-02
Published: 15 February 2022
View article titled, Abstract OT1-17-02: A phase II study of pembrolizumab plus fulvestrant in hormone receptor positive, HER-2 negative advanced/metastatic breast cancer patients
Journal Articles

Abstract 2249: Molecular landscape and actionable alterations in Chinese soft-tissue sarcoma patients

Hua Bao, Yue Wang, Rui Liu, Xue Wu, Yang Shao
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2249.
https://doi.org/10.1158/1538-7445.AM2021-2249
Published: 01 July 2021
View article titled, Abstract 2249: Molecular landscape and actionable alterations in Chinese soft-tissue sarcoma patients
Journal Articles

Tumor Fibroblast–Derived FGF2 Regulates Expression of SPRY1 in Esophageal Tumor–Infiltrating T Cells and Plays a Role in T-cell Exhaustion

Qing-yun Chen, Yi-ni Li, Xin-yue Wang, Xu Zhang, Yi Hu, Lei Li, Da-qin Suo, Ke Ni, Zhuo Li, Jia-rong Zhan, Ting-ting Zeng, Ying-hui Zhu, Yan Li, Li-jia Ma, Xin-Yuan Guan
Journal: Cancer Research
Cancer Res (2020) 80 (24): 5583–5596.
https://doi.org/10.1158/0008-5472.CAN-20-1542
Published: 15 December 2020
View article titled, Tumor Fibroblast–Derived FGF2 Regulates Expression of SPRY1 in Esophageal Tumor–Infiltrating T Cells and Plays a Role in T-cell Exhaustion
Open the PDF for Tumor Fibroblast–Derived FGF2 Regulates Expression of SPRY1 in Esophageal Tumor–Infiltrating T Cells and Plays a Role in T-cell Exhaustion in another window
Includes: Supplementary data
Journal Articles

ERINA Is an Estrogen-Responsive LncRNA That Drives Breast Cancer through the E2F1/RB1 Pathway

Zihui Fang, Yue Wang, Zehua Wang, Meishu Xu, Songrong Ren, Da Yang, Mei Hong, Wen Xie
Journal: Cancer Research
Cancer Res (2020) 80 (20): 4399–4413.
https://doi.org/10.1158/0008-5472.CAN-20-1031
Published: 15 October 2020
View article titled, <em>ERINA</em> Is an Estrogen-Responsive LncRNA That Drives Breast Cancer through the E2F1/RB1 Pathway
Open the PDF for <em>ERINA</em> Is an Estrogen-Responsive LncRNA That Drives Breast Cancer through the E2F1/RB1 Pathway in another window
Includes: Supplementary data
Journal Articles

Circadian Rhythm Is Disrupted by ZNF704 in Breast Carcinogenesis

Chao Yang, Jiajing Wu, Xinhua Liu, Yue Wang, Beibei Liu, Xing Chen, Xiaodi Wu, Dong Yan, Lulu Han, Shumeng Liu, Lin Shan, Yongfeng Shang
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (19): 4114–4128.
https://doi.org/10.1158/0008-5472.CAN-20-0493
Published: 02 October 2020
View article titled, Circadian Rhythm Is Disrupted by ZNF704 in Breast Carcinogenesis
Open the PDF for Circadian Rhythm Is Disrupted by ZNF704 in Breast Carcinogenesis in another window
Includes: Supplementary data
Journal Articles

Abstract 2267: MEDI5083, a novel CD40L-Fc fusion protein, activates the CD40 pathway on antigen-presenting cells and promotes robust anti-tumor immune responses in both hot and cold murine tumor models

Deepali Malhotra, Sean Turman, Kelly McGlinchey, Yaya Wang, Yue Wang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2267.
https://doi.org/10.1158/1538-7445.AM2020-2267
Published: 15 August 2020
View article titled, Abstract 2267: MEDI5083, a novel CD40L-Fc fusion protein, activates the CD40 pathway on antigen-presenting cells and promotes robust anti-tumor immune responses in both hot and cold murine tumor models