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Journal Articles

Abstract 5072: “Armed” oncolytic herpes simplex virus enables CD19 CAR-T for solid tumor cell treatment as a combination therapy

Yanxin Zheng, Yuanyuan Liu, Tianyi Deng, Yue Huang, Ziwen Liu, Borui Zhan, Xusha Zhou, Runbin Yan, Jiangtao Ren, Yun Xing, Guixing Wu, Yonghong Liu, Jing Zhao, Xiaoqing Chen, Grace Zhou
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5072.
https://doi.org/10.1158/1538-7445.AM2023-5072
Published: 04 April 2023
View article titled, Abstract 5072: “Armed” oncolytic herpes simplex virus enables CD19 CAR-T for solid tumor cell treatment as a combination therapy
Journal Articles

Abstract 5736: AZD9592: An EGFR-cMET bispecific antibody-drug conjugate (ADC) targeting key oncogenic drivers in non-small-cell lung cancer (NSCLC) and beyond

Frank Comer, Yariv Mazor, Elaine Hurt, Chunning Yang, Ryan Fleming, Harini Shandilya, Balakumar Vijayakrishnan, Meghan Sterba, Ruoyan Chen, Edward Rosfjord, Nicolas Floch, Anton I. Rosenbaum, Yue Huang, Jiaqi Yuan, Kevin Beaumont, Lisa Godfrey, Lara McGrath, Fernanda Arnaldez, Puja Sapra
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5736.
https://doi.org/10.1158/1538-7445.AM2023-5736
Published: 04 April 2023
View article titled, Abstract 5736: AZD9592: An EGFR-cMET bispecific antibody-drug conjugate (ADC) targeting key oncogenic drivers in non-small-cell lung cancer (NSCLC) and beyond
Journal Articles

Abstract 1765: Discovery and first disclosure of AZD8205, a B7-H4-targeted antibody-drug conjugate utilizing a novel topoisomerase I linker-warhead

Krista Kinneer, Niall J. Dickinson, Luke Masterson, Thais Cailleau, Ian Hutchinson, Balakumar Vijayakrishnan, Nazzareno Dimasi, R. James Christie, Mary McFarlane, Kathryn Ball, Arthur Lewis, Sofia Koch, Lee Brown, Yue Huang, Anton I. Rosenbaum, Jiaqi Yuan, Si Mou, Noel R. Monks, Jon Chesebrough, Ravinder Tammali, Judith Anderton, Darrin Sabol, Frances Anne Tosto, Philipp Wortmann, Zachary A. Cooper, Pauline Ryan, John Hood, Carlos Fernandez Teruel, Carlos Serra Traynor, Andy Pike, Michael Davies, Elisabetta Leo, Kimberly Cook, Nadia Luheshi, Philip W. Howard, Puja Sapra
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1765.
https://doi.org/10.1158/1538-7445.AM2022-1765
Published: 15 June 2022
View article titled, Abstract 1765: Discovery and first disclosure of AZD8205, a B7-H4-targeted antibody-drug conjugate utilizing a novel topoisomerase I linker-warhead
Journal Articles

Abstract 2597: Non-clinical studies of systemic delivery of oncolytic virus arms with IL-12 and anti-PD-1 antibody

Yanxin Zheng, Runbin Yan, Yuxin Tang, Borui Zhan, Yue Huang, Dongyao Ni, Xiaoqing Chen, Grace Zhou
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2597.
https://doi.org/10.1158/1538-7445.AM2021-2597
Published: 01 July 2021
View article titled, Abstract 2597: Non-clinical studies of systemic delivery of oncolytic virus arms with IL-12 and anti-PD-1 antibody
Journal Articles

Abstract 2651: Combination of an anti-angiogenic antibody with PD1/PDL1 blockade agents produces synergistic anti-tumor efficacy in preclinical models

Liting Xue, Haoyu Zhang, Qian Wang, Feng Li, Xinxin Li, Xiaohong Yu, Zhihong Lu, Yue Huang, Wenqing Yang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2651.
https://doi.org/10.1158/1538-7445.AM2021-2651
Published: 01 July 2021
View article titled, Abstract 2651: Combination of an anti-angiogenic antibody with PD1/PDL1 blockade agents produces synergistic anti-tumor efficacy in preclinical models
Journal Articles

Abstract P3-01-24: The cancer-associated TRPC5 opposite strand protein, a novel regulatory factor for cell proliferation in triple negative breast cancer

Yangyang Cui, Jinghui Peng, Yue Huang, Ziyi Fu, Hui Xie, Shui Wang
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-01-24.
https://doi.org/10.1158/1538-7445.SABCS19-P3-01-24
Published: 15 February 2020
View article titled, Abstract P3-01-24: The cancer-associated TRPC5 opposite strand protein, a novel regulatory factor for cell proliferation in triple negative breast cancer
Journal Articles

EBF1-Mediated Upregulation of Ribosome Assembly Factor PNO1 Contributes to Cancer Progression by Negatively Regulating the p53 Signaling Pathway

Aling Shen, Youqin Chen, Liya Liu, Yue Huang, Hongwei Chen, Fei Qi, Jiumao Lin, Zhiqing Shen, Xiangyan Wu, Meizhu Wu, Qiongyu Li, Liman Qiu, Na Yu, Thomas J. Sferra, Jun Peng
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (9): 2257–2270.
https://doi.org/10.1158/0008-5472.CAN-18-3238
Published: 01 May 2019
View article titled, EBF1-Mediated Upregulation of Ribosome Assembly Factor PNO1 Contributes to Cancer Progression by Negatively Regulating the p53 Signaling Pathway
Open the PDF for EBF1-Mediated Upregulation of Ribosome Assembly Factor PNO1 Contributes to Cancer Progression by Negatively Regulating the p53 Signaling Pathway in another window
Includes: Supplementary data
Journal Articles

Abstract 1927: Targeting IL-13RA2 in melanoma and pancreatic cancer

Rafal Zielinski, Izabela Tworowska, Stanislaw Skora, Aleksandra Rusin, Radjendirane Venugopal, Arumugam Jayakumar, Izabela Fokt, Yaan Kang, Jason Fleming, Yue Huang, Denise Herpai, Waldemar Debinski, Waldemar Priebe
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1927.
https://doi.org/10.1158/1538-7445.AM2018-1927
Published: 01 July 2018
View article titled, Abstract 1927: Targeting IL-13RA2 in melanoma and pancreatic cancer
Journal Articles

Abstract 3101: Pituitary homeobox 2 (PITX2) promotes thyroid carcinogenesis by activation of cyclin D2

Yue Huang, Guozhang Zhu
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3101.
https://doi.org/10.1158/1538-7445.AM10-3101
Published: 15 April 2010
View article titled, Abstract 3101: Pituitary homeobox 2 (PITX2) promotes thyroid carcinogenesis by activation of cyclin D2
Journal Articles

PITX2 is overexpressed in human thyroid cancer and functions in cell proliferation

Yue Huang, Guozhang Zhu
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): LB-166.
Published: 01 May 2008
View article titled, PITX2 is overexpressed in human thyroid cancer and functions in cell proliferation
Journal Articles

Overexpression of Bcl-xL Inhibits Ara-C-induced Mitochondrial Loss of Cytochrome c and Other Perturbations That Activate the Molecular Cascade of Apoptosis

Caryn Naekyung Kim, Xiaodong Wang, Yue Huang, Ana Maria Ibrado, Linda Liu, Guofu Fang, Kapil Bhalla
Journal: Cancer Research
Cancer Res (1997) 57 (15): 3115–3120.
Published: 01 August 1997
View article titled, Overexpression of Bcl-x<sub>L</sub> Inhibits Ara-C-induced Mitochondrial Loss of Cytochrome <em>c</em> and Other Perturbations That Activate the Molecular Cascade of Apoptosis
Open the PDF for Overexpression of Bcl-x<sub>L</sub> Inhibits Ara-C-induced Mitochondrial Loss of Cytochrome <em>c</em> and Other Perturbations That Activate the Molecular Cascade of Apoptosis in another window
Journal Articles

Overexpression of Bcl-2 or Bcl-xL Inhibits Ara-C-induced CPP32/Yama Protease Activity and Apoptosis of Human Acute Myelogenous Leukemia HL-60 Cells

Ana Maria Ibrado, Yue Huang, Guofu Fang, Linda Liu, Kapil Bhalla
Journal: Cancer Research
Cancer Res (1996) 56 (20): 4743–4748.
Published: 01 October 1996
View article titled, Overexpression of Bcl-2 or Bcl-x<sub>L</sub> Inhibits Ara-C-induced CPP32/Yama Protease Activity and Apoptosis of Human Acute Myelogenous Leukemia HL-60 Cells
Open the PDF for Overexpression of Bcl-2 or Bcl-x<sub>L</sub> Inhibits Ara-C-induced CPP32/Yama Protease Activity and Apoptosis of Human Acute Myelogenous Leukemia HL-60 Cells in another window