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Journal Articles

Abstract 1489: Deposition of genetically engineered T cell attracting antigen presenting cells in the glioma microenvironment with low intensity pulsed ultrasound-based blood-brain barrier opening triggers therapeutic responses in preclinical glioma models

Aria Sabbagh, Kevin Beccaria, Xiaoyang Ling, Anantha Marisetty, Martina Ott, Ling-Yuan Kong, Dexing Fang, Jun Wei, Carole Desseaux, Guillaume Bouchoux, Michael Canney, Alexandre Carpentier, Amy B. Heimberger
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1489.
https://doi.org/10.1158/1538-7445.AM2021-1489
Published: 01 July 2021
View article titled, Abstract 1489: Deposition of genetically engineered T cell attracting antigen presenting cells in the glioma microenvironment with low intensity pulsed ultrasound-based blood-brain barrier opening triggers therapeutic responses in preclinical glioma models
Journal Articles

Abstract 5746: CRISPR9-mediated FGL2-KO in tumor cells impairs tumor progression in brain and triggers antitumor immune memory systematically via NF-κB dependent Batf3 expression in DCs

Jun Yan, Qingnan Zhao, Konrad Gabrusiewicz, Ling-Yuan Kong, Longfei Huo, Xueqing Xia, Jun Wei, Jingda Xu, Eric Davis, Amy B. Heimberger, Shulin Li
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5746.
https://doi.org/10.1158/1538-7445.AM2018-5746
Published: 01 July 2018
View article titled, Abstract 5746: CRISPR9-mediated FGL2-KO in tumor cells impairs tumor progression in brain and triggers antitumor immune memory systematically via NF-<em>κ</em>B dependent Batf3 expression in DCs
Journal Articles

Abstract 4291: An optimized therapeutic nanoparticle delivery platform of miRNA in preclinical murine models of malignancy

Nasser K. Yaghi, Jun Wei, Ling-Yuan Kong, Yuuri Hashimoto, Edjah K. Nduom, Neal Huang, Xiaoyang Ling, Shouhao Zhou, Jonathan M. Levine, Virginia R. Fajt, Kiyoshi Tachikawa, Padmanabh Chivukula, David C. Webb, Joseph E. Payne, Amy B. Heimberger
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4291.
https://doi.org/10.1158/1538-7445.AM2015-4291
Published: 01 August 2015
View article titled, Abstract 4291: An optimized therapeutic nanoparticle delivery platform of miRNA in preclinical murine models of malignancy
Journal Articles

Abstract B62: miR-124 systemically enhances antitumor clearance by inhibiting STAT3 signaling and reversing glioma-associated immune suppression.

Jun Wei, Ling-Yuan Kong, Fei Wang, Shuo Xu, Tiffany Doucette, Sherise D. Ferguson, Yuhui Yang, Kayla McEnery, Krishan Jethwa, Olsi Gjyshi, Wei Qiao, Frederick Lang, Ganesh Rao, Greg N. Fuller, George A. Calin, Amy B. Heimberger
Journal: Cancer Research
Cancer Res (2013) 73 (1_Supplement): B62.
https://doi.org/10.1158/1538-7445.TUMIMM2012-B62
Published: 02 April 2014
View article titled, Abstract B62: miR-124 systemically enhances antitumor clearance by inhibiting STAT3 signaling and reversing glioma-associated immune suppression.
Journal Articles

miR-124 Inhibits STAT3 Signaling to Enhance T Cell–Mediated Immune Clearance of Glioma

Jun Wei, Fei Wang, Ling-Yuan Kong, Shuo Xu, Tiffany Doucette, Sherise D. Ferguson, Yuhui Yang, Kayla McEnery, Krishan Jethwa, Olsi Gjyshi, Wei Qiao, Nicholas B. Levine, Frederick F. Lang, Ganesh Rao, Gregory N. Fuller, George A. Calin, Amy B. Heimberger
Journal: Cancer Research
Cancer Res (2013) 73 (13): 3913–3926.
https://doi.org/10.1158/0008-5472.CAN-12-4318
Published: 30 June 2013
View article titled, miR-124 Inhibits STAT3 Signaling to Enhance T Cell–Mediated Immune Clearance of Glioma
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Includes: Supplementary data
Journal Articles

Abstract 5322: Glioma cancer stem cells induce immune suppressive macrophages

Adam SG Wu, Jun Wei, Ling-Yuan Kong, Yongtao Wang, Waldemar Priebe, Raymond Sawaya, Frederick F. Lang, Amy B. Heimberger
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5322.
https://doi.org/10.1158/1538-7445.AM10-5322
Published: 15 April 2010
View article titled, Abstract 5322: Glioma cancer stem cells induce immune suppressive macrophages
Journal Articles

Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma

Ling-Yuan Kong, Mohamed Abou-Ghazal, Arup Chakraborty, Greg Fuller, Timothy Madden, Wei Qiao, Wei Qiao, Elizabeth Grimm, Waldemar Priebe, Amy Heimberger
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4873.
Published: 01 May 2008
View article titled, Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
Journal Articles

A Novel Small Molecule Inhibitor of Signal Transducers and Activators of Transcription 3 Reverses Immune Tolerance in Malignant Glioma Patients

S. Farzana Hussain, Ling-Yuan Kong, Justin Jordan, Charles Conrad, Timothy Madden, Isabella Fokt, Waldemar Priebe, Amy B. Heimberger
Journal: Cancer Research
Cancer Res (2007) 67 (20): 9630–9636.
https://doi.org/10.1158/0008-5472.CAN-07-1243
Published: 17 October 2007
View article titled, A Novel Small Molecule Inhibitor of Signal Transducers and Activators of Transcription 3 Reverses Immune Tolerance in Malignant Glioma Patients
Open the PDF for A Novel Small Molecule Inhibitor of Signal Transducers and Activators of Transcription 3 Reverses Immune Tolerance in Malignant Glioma Patients in another window
Includes: Supplementary data
Journal Articles

Degrasyn Activates Proteasomal-Dependent Degradation of c-Myc

Geoffrey Bartholomeusz, Moshe Talpaz, William Bornmann, Ling-Yuan Kong, Nicholas J. Donato
Journal: Cancer Research
Cancer Res (2007) 67 (8): 3912–3918.
https://doi.org/10.1158/0008-5472.CAN-06-4464
Published: 17 April 2007
View article titled, Degrasyn Activates Proteasomal-Dependent Degradation of c-Myc
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Journal Articles

Matrix Metalloproteinase Activity Modulates Tumor Size, Cell Motility, and Cell Invasiveness in Murine Aggressive Fibromatosis

Yuan Kong, Raymond Poon, Puviindran Nadesan, Tamara Di Muccio, Riccardo Fodde, Rama Khokha, Benjamin A. Alman
Journal: Cancer Research
Cancer Res (2004) 64 (16): 5795–5803.
https://doi.org/10.1158/0008-5472.CAN-03-3112
Published: 16 August 2004
View article titled, Matrix Metalloproteinase Activity Modulates Tumor Size, Cell Motility, and Cell Invasiveness in Murine Aggressive Fibromatosis
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