1-20 of 51
Yu-Tzu Tai
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract CT043: Preliminary activity and safety of OBT076 in patients with CD205 positive solid tumors: Results from the phase 1b part C sequential expansion cohort

Free
Lauriane Eberst, Daniel Flora, Cécile Vicier, Rita Saude Conde, Harald Haeske, Andrew Dickinson, Chloe Nicholson, Christian Rohlff, Yu-Tzu Tai, Clément Dumont
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_2): CT043.
https://doi.org/10.1158/1538-7445.AM2025-CT043
Published: 25 April 2025
View articletitled, Abstract CT043: Preliminary activity and safety of OBT076 in patients with CD205 positive solid tumors: Results from the phase 1b part C sequential expansion cohort
Journal Articles

Retraction: Effects of Oligonucleotide N3′→P5′ Thio-phosphoramidate (GRN163) Targeting Telomerase RNA in Human Multiple Myeloma Cells

Free
Masaharu Akiyama, Teru Hideshima, Masood A. Shammas, Toshiaki Hayashi, Makoto Hamasaki, Yu-Tzu Tai, Paul Richardson, Sergei Gryaznov, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6): 937.
https://doi.org/10.1158/0008-5472.CAN-24-0518
Published: 15 March 2024
View articletitled, Retraction: Effects of Oligonucleotide N3′→P5′ Thio-phosphoramidate (GRN163) Targeting Telomerase RNA in Human Multiple Myeloma Cells
Open the PDF for Retraction: Effects of Oligonucleotide N3′→P5′ Thio-phosphoramidate (GRN163) Targeting Telomerase RNA in Human Multiple Myeloma Cells in another window
Journal Articles

Retraction: Cytokines Modulate Telomerase Activity in a Human Multiple Myeloma Cell Line

Free
Masaharu Akiyama, Teru Hideshima, Toshiaki Hayashi, Yu-Tzu Tai, Constantine S. Mitsiades, Nicholas Mitsiades, Dharminder Chauhan, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6): 940.
https://doi.org/10.1158/0008-5472.CAN-24-0516
Published: 15 March 2024
View articletitled, Retraction: Cytokines Modulate Telomerase Activity in a Human Multiple Myeloma Cell Line
Open the PDF for Retraction: Cytokines Modulate Telomerase Activity in a Human Multiple Myeloma Cell Line in another window
Journal Articles

Retraction: Mechanisms by which SGN-40, a Humanized Anti-CD40 Antibody, Induces Cytotoxicity in Human Multiple Myeloma Cells: Clinical Implications

Free
Yu-Tzu Tai, Laurence P. Catley, Constantine S. Mitsiades, Renate Burger, Klaus Podar, Reshma Shringpaure, Teru Hideshima, Dharminder Chauhan, Makoto Hamasaki, Kenji Ishitsuka, Paul Richardson, Steven P. Treon, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6): 936.
https://doi.org/10.1158/0008-5472.CAN-24-0520
Published: 15 March 2024
View articletitled, Retraction: Mechanisms by which SGN-40, a Humanized Anti-CD40 Antibody, Induces Cytotoxicity in Human Multiple Myeloma Cells: Clinical Implications
Open the PDF for Retraction: Mechanisms by which SGN-40, a Humanized Anti-CD40 Antibody, Induces Cytotoxicity in Human Multiple Myeloma Cells: Clinical Implications in another window
Journal Articles

Retraction: Nuclear Factor-κB p65 Mediates Tumor Necrosis Factor α-induced Nuclear Translocation of Telomerase Reverse Transcriptase Protein

Free
Masaharu Akiyama, Teru Hideshima, Toshiaki Hayashi, Yu-Tzu Tai, Constantine S. Mitsiades, Nicholas Mitsiades, Dharminder Chauhan, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6): 939.
https://doi.org/10.1158/0008-5472.CAN-24-0517
Published: 15 March 2024
View articletitled, Retraction: Nuclear Factor-κB p65 Mediates Tumor Necrosis Factor α-induced Nuclear Translocation of Telomerase Reverse Transcriptase Protein
Open the PDF for Retraction: Nuclear Factor-κB p65 Mediates Tumor Necrosis Factor α-induced Nuclear Translocation of Telomerase Reverse Transcriptase Protein in another window
Journal Articles

Retraction: Insulin-like Growth Factor-1 Induces Adhesion and Migration in Human Multiple Myeloma Cells via Activation of β1-Integrin and Phosphatidylinositol 3′-Kinase/AKT Signaling

Free
Yu-Tzu Tai, Klaus Podar, Laurence Catley, Yu-Hua Tseng, Masaharu Akiyama, Reshma Shringarpure, Renate Burger, Teru Hideshima, Dharminder Chauhan, Nicholas Mitsiades, Paul Richardson, Nikhil C. Munshi, C. Ronald Kahn, Constantine Mitsiades, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2024) 84 (6): 938.
https://doi.org/10.1158/0008-5472.CAN-24-0519
Published: 15 March 2024
View articletitled, Retraction: Insulin-like Growth Factor-1 Induces Adhesion and Migration in Human Multiple Myeloma Cells via Activation of β1-Integrin and Phosphatidylinositol 3′-Kinase/AKT Signaling
Open the PDF for Retraction: Insulin-like Growth Factor-1 Induces Adhesion and Migration in Human Multiple Myeloma Cells via Activation of β1-Integrin and Phosphatidylinositol 3′-Kinase/AKT Signaling in another window
Journal Articles

Abstract LB217: ROBO1 promotes homing, dissemination, and survival of multiple myeloma within the bone marrow microenvironment

Free
Giada Bianchi, Peter G. Czarnecki, Matthew Ho, Aldo M. Roccaro, Antonio Sacco, Yawara Kawano, Annamaria Gulla, Anil Aktas Samur, Tianzeng Cheng, Kenneth Wen, Yu-Tzu Tai, Maria Moscvin, Xinchen Wu, Gulden Camci-Unal, Matteo Claudio Da VIa, Niccolo Bolli, Ruben D. Carrasco, Irene M. Ghobrial, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB217.
https://doi.org/10.1158/1538-7445.AM2021-LB217
Published: 01 July 2021
View articletitled, Abstract LB217: ROBO1 promotes homing, dissemination, and survival of multiple myeloma within the bone marrow microenvironment
Journal Articles

Abstract 2240: Genomic profiling of smoldering multiple myeloma classifies distinct molecular groups

Free
Shankara Anand, Mark Bustoros, François Aguet, Romanos Sklavenitis-Pistofidis, Robert Redd, Benny Zhitomirsky, Andrew J. Dunford, Yu-Tzu Tai, Selina J. Chavda, Cody Boehner, Carl J. Neuse, Tineke Casneuf, Lorenzo Trippa, Chip Stewart, Kwee Yong, Irene Ghobrial, Gad Getz
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2240.
https://doi.org/10.1158/1538-7445.AM2021-2240
Published: 01 July 2021
View articletitled, Abstract 2240: Genomic profiling of smoldering multiple myeloma classifies distinct molecular groups
Journal Articles

Abstract 642: TRAF2 mediates sensitivity to immunomodulatory drugs via NF-κB and ERK signaling in myeloma cells

Free
Jiye Liu, Teru Hideshima, Lijie Xing, Su Wang, Wenrong Zhou, Daisuke Ogiya, Kenneth Wen, Yu-Tzu Tai, Yong Cang, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 642.
https://doi.org/10.1158/1538-7445.AM2020-642
Published: 15 August 2020
View articletitled, Abstract 642: TRAF2 mediates sensitivity to immunomodulatory drugs via NF-κB and ERK signaling in myeloma cells
Journal Articles

Abstract 383: APOBEC3B is induced by activation of DNA repair pathway and modulates the survival and treatment response in human multiple myeloma

Free
Lijie Xing, Jiye Liu, Liang Lin, Shih-Feng Cho, Kenneth Wen, Tengteng Yu, Gang An, Ligui Qiu, Kenneth Anderson, Yu-Tzu Tai
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 383.
https://doi.org/10.1158/1538-7445.AM2019-383
Published: 01 July 2019
View articletitled, Abstract 383: APOBEC3B is induced by activation of DNA repair pathway and modulates the survival and treatment response in human multiple myeloma
Journal Articles

Abstract 3832: A proliferation-inducing ligand (APRIL) directly impacts immune regulatory subsets to regulate suppressive multiple myeloma bone marrow microenvironment

Free
Yu-Tzu Tai, Liang Lin, Liji Xing, Liji Xing, Kenneth Wen, Nikhil Munshi, Paul Richardson, Kenneth Anderson
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3832.
https://doi.org/10.1158/1538-7445.AM2018-3832
Published: 01 July 2018
View articletitled, Abstract 3832: A proliferation-inducing ligand (APRIL) directly impacts immune regulatory subsets to regulate suppressive multiple myeloma bone marrow microenvironment
Journal Articles

Abstract 567: The lysosomal transporter SLC46A3 is a potential predictive biomarker for antibody-drug conjugates bearing the non-cleavable warheads SG3376 and DM1

Free
Krista Kinneer, Yu-Tzu Tai, Sriram Sridhar, John Meekin, Sandrina Phipps, Ben Ruddle, Ryan Fleming, Nazzareno Dimasi, Ronald Herbst, Arnaud Tiberghien, Luke Masterson, Philip Howard, Kenneth Anderson, David Tice
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 567.
https://doi.org/10.1158/1538-7445.AM2018-567
Published: 01 July 2018
View articletitled, Abstract 567: The lysosomal transporter SLC46A3 is a potential predictive biomarker for antibody-drug conjugates bearing the non-cleavable warheads SG3376 and DM1
Journal Articles

Abstract 3283: APRIL/BCMA activation promotes human multiple myeloma progression and further induces immunosuppressive bone marrow microenvironment

Free
Yu-Tzu Tai, Chirag Acharya, Gang An, Michele Moschetta, Mike Y. Zhong, Xiaoyan Feng, Michele Cea, Antonia Cagnetta, Kenneth Wen, Hans van Eenennaam, Andrea van Elsas, Nikhil Munshi, Kenneth Anderson
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3283.
https://doi.org/10.1158/1538-7445.AM2016-3283
Published: 15 July 2016
View articletitled, Abstract 3283: APRIL/BCMA activation promotes human multiple myeloma progression and further induces immunosuppressive bone marrow microenvironment
Journal Articles

Targeting the miR-221–222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma

Free
Jian-Jun Zhao, Zhang-Bo Chu, Yu Hu, Jianhong Lin, Zhongqiu Wang, Meng Jiang, Ming Chen, Xujun Wang, Yue Kang, Yangsheng Zhou, Triona Ni Chonghaile, Melanie E. Johncilla, Yu-Tzu Tai, Jin Q. Cheng, Antony Letai, Nikhil C. Munshi, Kenneth C. Anderson, Ruben D. Carrasco
Journal: Cancer Research
Cancer Res (2015) 75 (20): 4384–4397.
https://doi.org/10.1158/0008-5472.CAN-15-0457
Published: 14 October 2015
View articletitled, Targeting the miR-221–222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma
Open the PDF for Targeting the miR-221–222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma in another window
Includes: Supplementary data
Journal Articles

Abstract 394: A novel anti-a proliferation-inducing ligand hAPRIL.01A monoclonal antibody targets multiple myeloma cells in the bone marrow microenvironment

Free
Yu-Tzu Tai, Chirag Acharya, Gang An, Mike Y. Zhong, Xiaoyan Feng, Hua Jiang, Hans van Eenennaam, Andrea van Elsas, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 394.
https://doi.org/10.1158/1538-7445.AM2015-394
Published: 01 August 2015
View articletitled, Abstract 394: A novel anti-a proliferation-inducing ligand hAPRIL.01A monoclonal antibody targets multiple myeloma cells in the bone marrow microenvironment
Journal Articles

Abstract LB-38: Zebrafish embryos provide a permissive environment for the growth and dissemination of primary human myeloma and its precursor cells

Free
Dongdong MA, Arinze Nwokeji, Jianhong Lin, Yu-Tzu Tai, Nikhil Munshi, Robert I. Handin
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-38.
https://doi.org/10.1158/1538-7445.AM2014-LB-38
Published: 01 October 2014
View articletitled, Abstract LB-38: Zebrafish embryos provide a permissive environment for the growth and dissemination of primary human myeloma and its precursor cells
Journal Articles

Abstract 972: B-cell maturation antigen (BCMA) activation in human multiple myeloma cells promotes myeloma cell growth and survival in the bone marrow microenvironment via upregulated MCL-1 and NFκB signaling

Free
Yu-Tzu Tai, Chirag Acharya, Mike Y. Zhong, Michele Cea, Antonia Cagnetta, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 972.
https://doi.org/10.1158/1538-7445.AM2014-972
Published: 01 October 2014
View articletitled, Abstract 972: B-cell maturation antigen (BCMA) activation in human multiple myeloma cells promotes myeloma cell growth and survival in the bone marrow microenvironment via upregulated MCL-1 and NFκB signaling
Journal Articles

Abstract 644: Novel anti-B cell maturation antigen-monomethyl auristatin F antibody-drug conjugate (GSK2857916) induces potent and selective anti-multiple myeloma activity via enhanced effector function and direct tumor cell killing

Free
Yu-Tzu Tai, Chirag Acharya, Mike Y. Zhong, Michele Cea, Antonia Cagnetta, Patrick A. Mayes, Jenny Craigen, Louise Gliddon, James Smothers, Amanda L. Christie, Andrew L. Kung, Paul Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 644.
https://doi.org/10.1158/1538-7445.AM2014-644
Published: 01 October 2014
View articletitled, Abstract 644: Novel anti-B cell maturation antigen-monomethyl auristatin F antibody-drug conjugate (GSK2857916) induces potent and selective anti-multiple myeloma activity via enhanced effector function and direct tumor cell killing
Journal Articles

Selective and Potent Akt Inhibition Triggers Anti-Myeloma Activities and Enhances Fatal Endoplasmic Reticulum Stress Induced by Proteasome Inhibition

Free
Naoya Mimura, Teru Hideshima, Toshiyasu Shimomura, Rikio Suzuki, Hiroto Ohguchi, Ola Rizq, Shohei Kikuchi, Yasuhiro Yoshida, Francesca Cottini, Jana Jakubikova, Diana Cirstea, Gullu Gorgun, Jiro Minami, Yu-Tzu Tai, Paul G. Richardson, Teruhiro Utsugi, Atsushi Iwama, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2014) 74 (16): 4458–4469.
https://doi.org/10.1158/0008-5472.CAN-13-3652
Published: 13 August 2014
View articletitled, Selective and Potent Akt Inhibition Triggers Anti-Myeloma Activities and Enhances Fatal Endoplasmic Reticulum Stress Induced by Proteasome Inhibition
Open the PDF for Selective and Potent Akt Inhibition Triggers Anti-Myeloma Activities and Enhances Fatal Endoplasmic Reticulum Stress Induced by Proteasome Inhibition in another window
Includes: Supplementary data
Journal Articles

miR-30-5p Functions as a Tumor Suppressor and Novel Therapeutic Tool by Targeting the Oncogenic Wnt/β-Catenin/BCL9 Pathway

Free
Jian-Jun Zhao, Jianhong Lin, Di Zhu, Xujun Wang, Daniel Brooks, Ming Chen, Zhang-Bo Chu, Kohichi Takada, Bryan Ciccarelli, Samir Admin, Jianguo Tao, Yu-Tzu Tai, Steven Treon, Geraldine Pinkus, Winston Patrick Kuo, Teru Hideshima, Mary Bouxsein, Nikhil Munshi, Kenneth Anderson, Ruben Carrasco
Journal: Cancer Research
Cancer Res (2014) 74 (6): 1801–1813.
https://doi.org/10.1158/0008-5472.CAN-13-3311-T
Published: 13 March 2014
View articletitled, miR-30-5p Functions as a Tumor Suppressor and Novel Therapeutic Tool by Targeting the Oncogenic Wnt/β-Catenin/BCL9 Pathway
Open the PDF for miR-30-5p Functions as a Tumor Suppressor and Novel Therapeutic Tool by Targeting the Oncogenic Wnt/β-Catenin/BCL9 Pathway in another window
Includes: Supplementary data