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Yu Zhan
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Journal Articles

Abstract 4033: Pan-exon mutant KIT inhibitor DCC-3009 demonstrates tumor regressions in preclinical gastrointestinal stromal tumor models

Bryan D. Smith, Subha Vogeti, Timothy M. Caldwell, Hanumaiah Telikepalli, Yu Mi Ahn, Gada Al-Ani, Stacie L. Bulfer, Andrew Greenwood, Cale L. Heiniger, Joshua W. Large, Cynthia B. Leary, Wei-Ping Lu, Kylie Luther, William C. Patt, Max D. Petty, Yeni K. Romero, Forrest A. Stanley, Kristen L. Stoltz, Daniel C. Tanner, Sihyung Yang, Yu Zhan, Bertrand Le Bourdonnec, Daniel L. Flynn
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4033.
https://doi.org/10.1158/1538-7445.AM2023-4033
Published: 04 April 2023
View article titled, Abstract 4033: Pan-exon mutant KIT inhibitor DCC-3009 demonstrates tumor regressions in preclinical gastrointestinal stromal tumor models
Journal Articles

Abstract 3600: DCC-3116, a first-in-class selective inhibitor of ULK1/2 kinases and autophagy, synergizes with the KRASG12C inhibitor sotorasib resulting in tumor regression in KRAS mutant NSCLC xenograft models

Martin McMahon, Madhumita Bogdan, Mary J. Timson, Hikmat Al-Hashimi, Phaedra Ghazi, Yu Zhan, Bryan D. Smith, Conan G. Kinsey, Daniel L. Flynn
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3600.
https://doi.org/10.1158/1538-7445.AM2022-3600
Published: 15 June 2022
View article titled, Abstract 3600: DCC-3116, a first-in-class selective inhibitor of ULK1/2 kinases and autophagy, synergizes with the KRAS<sup>G12C</sup> inhibitor sotorasib resulting in tumor regression in KRAS mutant NSCLC xenograft models
Journal Articles

Abstract 5833: Senescence is a central response to chemotherapy in ovarian cancer

Michael Skulimowski, Llilians Calvo-Gonzales, Shuofei Cheng, Isabelle Clément, Lise Portelance, Yu Zhan, Euridice Carmona, Manon de Ladurantaye, Julie Lafontaine, Kurosh Rahimi, Diane Provencher, Anne-Marie Mes-Masson, Francis Rodier
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5833.
https://doi.org/10.1158/1538-7445.AM2020-5833
Published: 15 August 2020
View article titled, Abstract 5833: Senescence is a central response to chemotherapy in ovarian cancer
Journal Articles

Abstract A074: Aberrant activation of a gastrointestinal transcriptional circuit in prostate cancer mediates castration resistance

Shipra Shukla, Joanna Cyrta, Devan Murphy, Edward Walczak, Leili Ran, Praveen Agrawal, Yuanyuan Xie, Yuedan Chen, Shangqian Wang, Yu Zhan, Wai Pung E. Wong, Andrea Sboner, Himisha Beltran, Juan-Miguel Mosquera, Jessica Sher, Zhen Cao, John Wongvipat, Richard P. Koche, Anuradha Gopalan, Deyou Zheng, Mark Rubin, Howard I. Scher, Ping Chi, Yu Chen
Journal: Cancer Research
Cancer Res (2018) 78 (16_Supplement): A074.
https://doi.org/10.1158/1538-7445.PRCA2017-A074
Published: 14 August 2018
View article titled, Abstract A074: Aberrant activation of a gastrointestinal transcriptional circuit in prostate cancer mediates castration resistance
Journal Articles

Abstract 867: Blocking breast cancer metastasis by targeting HuR-FOXQ1 signaling axis

Xiaoqing Wu, Gulhumay Gardashova, Lan Lan, Yu Zhan, Jiajun Liu, Dan A. Dixon, Jeffrey Aubé, Danny R. Welch, Liang Xu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 867.
https://doi.org/10.1158/1538-7445.AM2018-867
Published: 01 July 2018
View article titled, Abstract 867: Blocking breast cancer metastasis by targeting HuR-FOXQ1 signaling axis
Journal Articles

Abstract 2863: Dissecting the structural basis for inhibitors of RNA-binding proteins

Lan Lan, Minli Xing, Xiaoqing Wu, Philip Gao, Justin T. Douglas, Yu Zhan, Gulhumay Gardashova, Jiajun Liu, Robert P. Hanzlik, Jeffrey Aubé, Kristi L. Neufeld, Berl R. Oakley, Roberto N. De Guzman, Liang Xu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2863.
https://doi.org/10.1158/1538-7445.AM2018-2863
Published: 01 July 2018
View article titled, Abstract 2863: Dissecting the structural basis for inhibitors of RNA-binding proteins
Journal Articles

ETV1-Positive Cells Give Rise to BRAFV600E-Mutant Gastrointestinal Stromal Tumors

Leili Ran, Devan Murphy, Jessica Sher, Zhen Cao, Shangqian Wang, Edward Walczak, Youxin Guan, Yuanyuan Xie, Shipra Shukla, Yu Zhan, Cristina R. Antonescu, Yu Chen, Ping Chi
Journal: Cancer Research
Cancer Res (2017) 77 (14): 3758–3765.
https://doi.org/10.1158/0008-5472.CAN-16-3510
Published: 13 July 2017
View article titled, ETV1-Positive Cells Give Rise to <em>BRAF<sup>V600E</sup></em>-Mutant Gastrointestinal Stromal Tumors
Open the PDF for ETV1-Positive Cells Give Rise to <em>BRAF<sup>V600E</sup></em>-Mutant Gastrointestinal Stromal Tumors in another window
Includes: Supplementary data
Journal Articles

Gut Microbiota Protects against Gastrointestinal Tumorigenesis Caused by Epithelial Injury

Yu Zhan, Po-Ju Chen, William D. Sadler, Fuyuan Wang, Sara Poe, Gabriel Núñez, Kathryn A. Eaton, Grace Y. Chen
Journal: Cancer Research
Cancer Res (2013) 73 (24): 7199–7210.
https://doi.org/10.1158/0008-5472.CAN-13-0827
Published: 16 December 2013
View article titled, Gut Microbiota Protects against Gastrointestinal Tumorigenesis Caused by Epithelial Injury
Open the PDF for Gut Microbiota Protects against Gastrointestinal Tumorigenesis Caused by Epithelial Injury in another window
Includes: Supplementary data