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Journal Articles

Abstract CT010: Phase I dose-escalation and expansion study of JS107, a claudin 18.2 (CLDN18.2)-targeting antibody-drug conjugate (ADC), as monotherapy or in combination for patients (pts) with advanced solid tumors

Cancer Res (2025) 85 (8_Supplement_2): CT010.

https://doi.org/10.1158/1538-7445.AM2025-CT010

Published: 25 April 2025

View articletitled, Abstract CT010: Phase I dose-escalation and expansion study of JS107, a claudin 18.2 (CLDN18.2)-targeting antibody-drug conjugate (ADC), as monotherapy or in combination for patients (pts) with advanced solid tumors

Journal Articles

Abstract 391: Pharmacological suppression of neuroblastoma growth via RBM39 degradation by the molecular glue PPI-011

Yu Cao, Qilei Han, Penxuan Ren, Bin Zhang, Lin Wang, Xianglei Zhang, Lei Zhou, Song Feng, James X. Rong, Lianghe Mei, Kai Li, Fang Bai

Cancer Res (2025) 85 (8_Supplement_1): 391.

https://doi.org/10.1158/1538-7445.AM2025-391

Published: 21 April 2025

View articletitled, Abstract 391: Pharmacological suppression of neuroblastoma growth via RBM39 degradation by the molecular glue PPI-011

Journal Articles

Abstract 5921: Correlation between MET amplification/overexpression status and response to MCLA-129 in advanced non-small-cell lung cancer (NSCLC): biomarker results from a phase 1 trial

Cancer Res (2025) 85 (8_Supplement_1): 5921.

https://doi.org/10.1158/1538-7445.AM2025-5921

Published: 21 April 2025

View articletitled, Abstract 5921: Correlation between MET amplification/overexpression status and response to MCLA-129 in advanced non-small-cell lung cancer (NSCLC): biomarker results from a phase 1 trial

Journal Articles

Abstract CT153: Pemigatinib in Chinese patients with advanced/metastatic or surgically unresectable cholangiocarcinoma Including FGFR2 fusion or rearrangement: Updated overall survival from an open-label, single-arm, multicenter Phase II study

Cancer Res (2023) 83 (8_Supplement): CT153.

https://doi.org/10.1158/1538-7445.AM2023-CT153

Published: 14 April 2023

View articletitled, Abstract CT153: Pemigatinib in Chinese patients with advanced/metastatic or surgically unresectable cholangiocarcinoma Including FGFR2 fusion or rearrangement: Updated overall survival from an open-label, single-arm, multicenter Phase II study

Journal Articles

Abstract 5528: Palliative and end of life care utilization in Asian and White patients with stage IV lung cancer

Xiao Hu, John W. Melson, Stacey Pan, Yana Salei, Yu Cao

Cancer Res (2023) 83 (7_Supplement): 5528.

https://doi.org/10.1158/1538-7445.AM2023-5528

Published: 04 April 2023

View articletitled, Abstract 5528: Palliative and end of life care utilization in Asian and White patients with stage IV lung cancer

Journal Articles

AMPK Alpha-1 Intrinsically Regulates the Function and Differentiation of Tumor Myeloid-Derived Suppressor Cells

Jimena Trillo-Tinoco, Rosa A. Sierra, Eslam Mohamed, Yu Cao, Álvaro de Mingo-Pulido, Danielle L. Gilvary, Carmen M. Anadon, Tara Lee Costich, Sheng Wei, Elsa R. Flores, Brian Ruffell, José R. Conejo-Garcia, Paulo C. Rodriguez

Cancer Res (2019) 79 (19): 5034–5047.

https://doi.org/10.1158/0008-5472.CAN-19-0880

Published: 01 October 2019

View articletitled, AMPK Alpha-1 Intrinsically Regulates the Function and Differentiation of Tumor Myeloid-Derived Suppressor Cells

Includes: Supplementary data

Journal Articles

Abstract 3275: Inhibition of ER-stress factor C/EBP homologous protein (Chop) with LNAplus™ antisense-oligonucleotides to improve immunotherapy of cancer

Richard Klar, Yu Cao, Eslam Mohamed, Sven Michel, Monika Schell, Lisa Hinterwimmer, Stefanie Raith, Paulo Rodriguez, Frank Jaschinski

Cancer Res (2019) 79 (13_Supplement): 3275.

https://doi.org/10.1158/1538-7445.AM2019-3275

Published: 01 July 2019

View articletitled, Abstract 3275: Inhibition of ER-stress factor C/EBP homologous protein (Chop) with LNAplus™ antisense-oligonucleotides to improve immunotherapy of cancer

Journal Articles

Abstract 2572: The novel long non-coding RNA PANCR is an intracellular p53 activator

Yu Cao

Cancer Res (2017) 77 (13_Supplement): 2572.

https://doi.org/10.1158/1538-7445.AM2017-2572

Published: 01 July 2017

View articletitled, Abstract 2572: The novel long non-coding RNA PANCR is an intracellular p53 activator

Journal Articles

Abstract 665: Blocking IL-1-NF-kB axis inhibits Kras-induced pancreatic ductal adenocarcinoma

Jianhua Ling, Jie Fu, Min Wu, Yu Cao, Paul Chiao

Cancer Res (2016) 76 (14_Supplement): 665.

https://doi.org/10.1158/1538-7445.AM2016-665

Published: 15 July 2016

View articletitled, Abstract 665: Blocking IL-1-NF-kB axis inhibits Kras-induced pancreatic ductal adenocarcinoma

Journal Articles

Abstract 1301: Inter- and intra-tumoral immune and genomic heterogeneity in patients with metastatic melanoma

Alexandre Reuben, Zachary A. Cooper, Whijae Roh, Yu Cao, Jacob Austin-Breneman, Hong Jiang, Rodabe N. Amaria, Pei-Ling Chen, Michael T. Tetzlaff, Lynda Chin, Andrew Futreal, Michael A. Davies, Jennifer A. Wargo

Cancer Res (2015) 75 (15_Supplement): 1301.

https://doi.org/10.1158/1538-7445.AM2015-1301

Published: 01 August 2015

View articletitled, Abstract 1301: Inter- and intra-tumoral immune and genomic heterogeneity in patients with metastatic melanoma

Journal Articles

Abstract LB-222: Long-term subclonal evolution of CLL from immune selective pressure after allogeneic stem cell transplant and donor lymphocyte infusion

Haven R. Garber, Hannah Beird, Yu Cao, Jianhua Zhang, Rachel Sargent, Pei Lin, Sahil Seth, Xingzhi Song, Huandong Sun, Xizeng Mao, Lisa St John, Karen Clise-Dwyer, Gheath Alatrash, P. Andrew Futreal, Jeffrey J. Molldrem

Cancer Res (2015) 75 (15_Supplement): LB-222.

https://doi.org/10.1158/1538-7445.AM2015-LB-222

Published: 01 August 2015

View articletitled, Abstract LB-222: Long-term subclonal evolution of CLL from immune selective pressure after allogeneic stem cell transplant and donor lymphocyte infusion

Journal Articles

Abstract 5348: Impaired self-renewal and colitis susceptibility of colonic mucosa in mice lacking AKR1B8

Yi Shen, Jun Ma, Ruilan Yan, Hongyan Ling, Xiaoning Li, Wancai Yang, John Gao, Yiwen Bu, Ahmed Alsalman, Cheifei Huang, Yu Cao, Shuangbai Zhou, Laxiang Wan, Yingchun He, Zhiqi Wang, Ali Khazaal, Mei Chris Huang, Duan-Fang Liao, Deliang Cao

Cancer Res (2014) 74 (19_Supplement): 5348.

https://doi.org/10.1158/1538-7445.AM2014-5348

Published: 01 October 2014

View articletitled, Abstract 5348: Impaired self-renewal and colitis susceptibility of colonic mucosa in mice lacking AKR1B8

Journal Articles

Abstract 4512: Construction and characterization of novel, human serine protease granzyme B-based cancer therapeutics targeting the TNFR family member Fn14

Hong Zhou, Khalid A. Mohamedali, Yu Cao, Mary Migliorini, Lawrence H. Cheung, Walter N. Hittelman, Jeffrey A. Winkles, Michael G. Rosenblum

Cancer Res (2014) 74 (19_Supplement): 4512.

https://doi.org/10.1158/1538-7445.AM2014-4512

Published: 01 October 2014

View articletitled, Abstract 4512: Construction and characterization of novel, human serine protease granzyme B-based cancer therapeutics targeting the TNFR family member Fn14

Journal Articles

Abstract 4509: The fully human, proapoptotic fusion protein Granzyme B/VEGF₁₂₁ targets tumor vasculature and inhibits tumor growth

Khalid A. Mohamedali, Lawrence H. Cheung, Yu Cao, Walter N. Hittelman, Michael G. Rosenblum

Cancer Res (2014) 74 (19_Supplement): 4509.

https://doi.org/10.1158/1538-7445.AM2014-4509

Published: 01 October 2014

View articletitled, Abstract 4509: The fully human, proapoptotic fusion protein Granzyme B/VEGF121 targets tumor vasculature and inhibits tumor growth

Journal Articles

Abstract C71: DEAR1 orchestrates selective control over the epithelial-mesenchymal transition axis of TGFβ's function

Nanyue Chen, Seetharaman Balasenthil, Yu Cao, Ann M. Killary

Cancer Res (2013) 73 (3_Supplement): C71.

https://doi.org/10.1158/1538-7445.TIM2013-C71

Published: 01 May 2014

View articletitled, Abstract C71: DEAR1 orchestrates selective control over the epithelial-mesenchymal transition axis of TGFβ's function

Journal Articles

Abstract 5479: The fully human pro-apoptotic fusion toxin Granzyme B/VEGF₁₂₁ targets vasculature and ablates tumor growth.

Khalid A. Mohamedali, Lawrence H. Cheung, Yu Cao, Walter N. Hittelman, Michael G. Rosenblum

Cancer Res (2013) 73 (8_Supplement): 5479.

https://doi.org/10.1158/1538-7445.AM2013-5479

Published: 15 April 2013

View articletitled, Abstract 5479: The fully human pro-apoptotic fusion toxin Granzyme B/VEGF121 targets vasculature and ablates tumor growth.

Journal Articles

Abstract 860: In vitro and in vivo studies of a novel, functionalized, completely human serine protease targeting Her2/neu. Activity against Herceptin- and multi-drug resistant tumor cells .

Yu Cao, Khalid A. Mohamedali, John W. Marks, Lawrence H. Cheung, Walter N. Hittelman, Michael G. Rosenblum

Cancer Res (2013) 73 (8_Supplement): 860.

https://doi.org/10.1158/1538-7445.AM2013-860

Published: 15 April 2013

View articletitled, Abstract 860: In vitro and in vivo studies of a novel, functionalized, completely human serine protease targeting Her2/neu. Activity against Herceptin- and multi-drug resistant tumor cells .

Journal Articles

Abstract 2185: Development and characterization of the fully human chimeric protein GrB-TWEAK targeting Fn14-positive solid tumor cells.

Hong Zhou, Mary Migliorini, Yu Cao, Lawrence H. Cheung, Walter N. Hittelman, Jeffrey A. Winkles, Michael G. Rosenblum

Cancer Res (2013) 73 (8_Supplement): 2185.

https://doi.org/10.1158/1538-7445.AM2013-2185

Published: 15 April 2013

View articletitled, Abstract 2185: Development and characterization of the fully human chimeric protein GrB-TWEAK targeting Fn14-positive solid tumor cells.

Journal Articles

Abstract 4426: Metabolism and tissue distribution of curcumin in mouse GI tract.

Yu Cao, Ming Chiu, Kenneth K. Chan, Ronald Xu, Zhongfa Liu

Cancer Res (2013) 73 (8_Supplement): 4426.

https://doi.org/10.1158/1538-7445.AM2013-4426

Published: 15 April 2013

View articletitled, Abstract 4426: Metabolism and tissue distribution of curcumin in mouse GI tract.

Journal Articles

Abstract 2730: Anti-Her2/neu immunotoxins: Impact of monovalent and bivalent designs on in vitro and in vivo antitumor efficacy

Yu Cao, John W. Marks, Zhigang Liu, Lawrence H. Chueng, Walter N. Hittelman, Michael G. Rosenblum

Cancer Res (2012) 72 (8_Supplement): 2730.

https://doi.org/10.1158/1538-7445.AM2012-2730

Published: 15 April 2012

View articletitled, Abstract 2730: Anti-Her2/neu immunotoxins: Impact of monovalent and bivalent designs on in vitro and in vivo antitumor efficacy

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Abstract CT010: Phase I dose-escalation and expansion study of JS107, a claudin 18.2 (CLDN18.2)-targeting antibody-drug conjugate (ADC), as monotherapy or in combination for patients (pts) with advanced solid tumors

Abstract 391: Pharmacological suppression of neuroblastoma growth via RBM39 degradation by the molecular glue PPI-011

Abstract 5921: Correlation between MET amplification/overexpression status and response to MCLA-129 in advanced non-small-cell lung cancer (NSCLC): biomarker results from a phase 1 trial

Abstract CT153: Pemigatinib in Chinese patients with advanced/metastatic or surgically unresectable cholangiocarcinoma Including FGFR2 fusion or rearrangement: Updated overall survival from an open-label, single-arm, multicenter Phase II study

Abstract 5528: Palliative and end of life care utilization in Asian and White patients with stage IV lung cancer

AMPK Alpha-1 Intrinsically Regulates the Function and Differentiation of Tumor Myeloid-Derived Suppressor Cells

Abstract 3275: Inhibition of ER-stress factor C/EBP homologous protein (Chop) with LNAplus™ antisense-oligonucleotides to improve immunotherapy of cancer

Abstract 2572: The novel long non-coding RNA PANCR is an intracellular p53 activator

Abstract 665: Blocking IL-1-NF-kB axis inhibits Kras-induced pancreatic ductal adenocarcinoma

Abstract 1301: Inter- and intra-tumoral immune and genomic heterogeneity in patients with metastatic melanoma

Abstract LB-222: Long-term subclonal evolution of CLL from immune selective pressure after allogeneic stem cell transplant and donor lymphocyte infusion

Abstract 5348: Impaired self-renewal and colitis susceptibility of colonic mucosa in mice lacking AKR1B8

Abstract 4512: Construction and characterization of novel, human serine protease granzyme B-based cancer therapeutics targeting the TNFR family member Fn14

Abstract 4509: The fully human, proapoptotic fusion protein Granzyme B/VEGF₁₂₁ targets tumor vasculature and inhibits tumor growth

Abstract C71: DEAR1 orchestrates selective control over the epithelial-mesenchymal transition axis of TGFβ's function

Abstract 5479: The fully human pro-apoptotic fusion toxin Granzyme B/VEGF₁₂₁ targets vasculature and ablates tumor growth.

Abstract 860: In vitro and in vivo studies of a novel, functionalized, completely human serine protease targeting Her2/neu. Activity against Herceptin- and multi-drug resistant tumor cells .

Abstract 2185: Development and characterization of the fully human chimeric protein GrB-TWEAK targeting Fn14-positive solid tumor cells.

Abstract 4426: Metabolism and tissue distribution of curcumin in mouse GI tract.

Abstract 2730: Anti-Her2/neu immunotoxins: Impact of monovalent and bivalent designs on in vitro and in vivo antitumor efficacy

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