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Youyuan Xu
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Journal Articles

Abstract LB-303: Anti-IGF1R therapy with dalotuzumab is efficacious in pre-clinical models of erlotinib refractory NSCLC

Youyuan Xu, Sharda Jha, Kara Sykes, Cloud P. Paweletz, Michael Nebozhyn, Igor Feldman, andrey Loboda, john Reilly, Christopher Winter, Theresa Zhang, Sriram Sathyanarayanan
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-303.
https://doi.org/10.1158/1538-7445.AM10-LB-303
Published: 15 April 2010
View article titled, Abstract LB-303: Anti-IGF1R therapy with dalotuzumab is efficacious in pre-clinical models of erlotinib refractory NSCLC
Journal Articles

Reactivation of Androgen Receptor–Regulated TMPRSS2:ERG Gene Expression in Castration-Resistant Prostate Cancer

Changmeng Cai, Hongyun Wang, Youyuan Xu, Shaoyong Chen, Steven P. Balk
Journal: Cancer Research
Cancer Res (2009) 69 (15): 6027–6032.
https://doi.org/10.1158/0008-5472.CAN-09-0395
Published: 29 July 2009
View article titled, Reactivation of Androgen Receptor–Regulated <em>TMPRSS2:ERG</em> Gene Expression in Castration-Resistant Prostate Cancer
Open the PDF for Reactivation of Androgen Receptor–Regulated <em>TMPRSS2:ERG</em> Gene Expression in Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract #2809: Combination treatment with the anti-IGF1R antibody MK-0646 and the mTOR inhibitor deforolimus leads to more effective PI3K pathway targeting and anti-tumor activity

Sriram Sathyanarayanan, Sharda Jha, Richard Klinghoffer, Youyuan Xu, Mark Bittinger, Jason Frazier, Alessandra Di Bacco, Michael Chastain, Astrid Kral, Nancy Kohl, Brian Haines, Katharine Yen, Shailaja Kasibhatla, Christopher Winter
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2809.
Published: 01 May 2009
View article titled, Abstract #2809: Combination treatment with the anti-IGF1R antibody MK-0646 and the mTOR inhibitor deforolimus leads to more effective PI3K pathway targeting and anti-tumor activity
Journal Articles

Androgens Induce Prostate Cancer Cell Proliferation through Mammalian Target of Rapamycin Activation and Post-transcriptional Increases in Cyclin D Proteins

Youyuan Xu, Shao-Yong Chen, Kenneth N. Ross, Steven P. Balk
Journal: Cancer Research
Cancer Res (2006) 66 (15): 7783–7792.
https://doi.org/10.1158/0008-5472.CAN-05-4472
Published: 02 August 2006
View article titled, Androgens Induce Prostate Cancer Cell Proliferation through Mammalian Target of Rapamycin Activation and Post-transcriptional Increases in Cyclin D Proteins
Open the PDF for Androgens Induce Prostate Cancer Cell Proliferation through Mammalian Target of Rapamycin Activation and Post-transcriptional Increases in Cyclin D Proteins in another window
Journal Articles

Androgen receptor signaling induces prostate cancer cell proliferation through mTOR activation and post-transcriptional increases in cyclin D proteins

Youyuan Xu, Shaoyong Chen, Steven P. Balk
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 688.
Published: 15 April 2006
View article titled, Androgen receptor signaling induces prostate cancer cell proliferation through mTOR activation and post-transcriptional increases in cyclin D proteins