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Younghun Han
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Journal Articles

Abstract 5228: Genome-wide association study and LD score regression analysis for cholangiocarcinoma

Younghun Han, Katherine A. McGlynn, Jinyoung Byun, Matthew A. Cooley, Manal M. Hassan, Christopher I. Amos, Lewis R. Roberts, The International Consortium for the Genetics of Biliary Tract Cancers
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5228.
https://doi.org/10.1158/1538-7445.AM2023-5228
Published: 04 April 2023
View article titled, Abstract 5228: Genome-wide association study and LD score regression analysis for cholangiocarcinoma
Journal Articles

Abstract 5218: Genome-wide association study of African Americans reveals new susceptibility loci contributing to lung cancer and mechanisms of population-specific etiology

Jinyoung Byun, Younghun Han, Xiangjun Xiao, Christine Lusk, Hoda J. Badr, Rayjean Hung, Ann G. Schwartz, Christopher I. Amos, INTEGRAL Consortium
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5218.
https://doi.org/10.1158/1538-7445.AM2023-5218
Published: 04 April 2023
View article titled, Abstract 5218: Genome-wide association study of African Americans reveals new susceptibility loci contributing to lung cancer and mechanisms of population-specific etiology
Journal Articles

Abstract 2121: Genetic correlation between lung cancer and environmental exposures

Rowland West Pettit, Jinyoung Byun, Younghun Han, Jacob Edelson, Quinn Ostrom, Kyle Walsh, Melissa Bondy, James McKay, Christopher Amos, INTEGRAL Consortium
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2121.
https://doi.org/10.1158/1538-7445.AM2020-2121
Published: 15 August 2020
View article titled, Abstract 2121: Genetic correlation between lung cancer and environmental exposures
Journal Articles

Abstract 3396: Multiethnic genome-wide meta-analysis of 34,329 cases and 35,732 controls identifies cross-ancestry loci for lung cancer susceptibility

Jinyoung Byun, Xiangjun Xiao, Younghun Han, Yafang Li, Ryan Sun, Xihao Li, Hufeng Zhou, Xihong Lin, James McKay, Rayjean Hung, Christopher Amos, INTEGRAL Consortium
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3396.
https://doi.org/10.1158/1538-7445.AM2020-3396
Published: 15 August 2020
View article titled, Abstract 3396: Multiethnic genome-wide meta-analysis of 34,329 cases and 35,732 controls identifies cross-ancestry loci for lung cancer susceptibility
Journal Articles

Abstract 2327: Genetic correlation analysis identifies glioma heritability enrichment in immune cell types and novel protective associations with auto-immune conditions

Quinn T. Ostrom, Jacob Edelson, Jinyoung Byun, Younghun Han, GLIOGENE Consortium, Kyle Walsh, Christopher Amos, Melissa Bondy
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2327.
https://doi.org/10.1158/1538-7445.AM2020-2327
Published: 15 August 2020
View article titled, Abstract 2327: Genetic correlation analysis identifies glioma heritability enrichment in immune cell types and novel protective associations with auto-immune conditions
Journal Articles

Abstract 1583: Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development

Yafang Li, Xiangjun Xiao, Ivan Gorlov, Younghun Han, Rayjean Hung, Christopher Amos
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1583.
https://doi.org/10.1158/1538-7445.AM2019-1583
Published: 01 July 2019
View article titled, Abstract 1583: Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development
Journal Articles

Abstract 1593: Genetic interactions in lung cancer using machine-learning approaches in genome-wide association studies

Jinyoung Byun, Younghun Han, Christopher I. Amos
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1593.
https://doi.org/10.1158/1538-7445.AM2019-1593
Published: 01 July 2019
View article titled, Abstract 1593: Genetic interactions in lung cancer using machine-learning approaches in genome-wide association studies
Journal Articles

Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk

Yesha M. Patel, Sunghim L. Park, Younghun Han, Lynne R. Wilkens, Heike Bickeböller, Albert Rosenberger, Neil Caporaso, Maria Teresa Landi, Irene Brüske, Angela Risch, Yongyue Wei, David C. Christiani, Paul Brennan, Richard Houlston, James McKay, John McLaughlin, Rayjean Hung, Sharon Murphy, Daniel O. Stram, Christopher Amos, Loïc Le Marchand
Journal: Cancer Research
Cancer Res (2016) 76 (19): 5768–5776.
https://doi.org/10.1158/0008-5472.CAN-16-0446
Published: 02 October 2016
View article titled, Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk
Open the PDF for Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk in another window
Includes: Supplementary data
Journal Articles

Abstract 2569: A genome wide association study of lung cancer identifies 11 novel susceptibility loci

James Dowling Mckay, Yafang Li, Younghun Han, Xiangjun Xioa, John Field, Xuchen Zong, Heike Bickeböller, David C. Christiani, Paul Brennan, Maria-Teresa Landi, Rayjean Hung, Christopher I. Amos, on behalf of the OncoArray Lung Cancer Group
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2569.
https://doi.org/10.1158/1538-7445.AM2016-2569
Published: 15 July 2016
View article titled, Abstract 2569: A genome wide association study of lung cancer identifies 11 novel susceptibility loci
Journal Articles

Abstract 2567: Characterizing histologic subtypes in lung cancer using principal component analysis

Jinyoung Byun, Younghun Han, Christopher I. Amos
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2567.
https://doi.org/10.1158/1538-7445.AM2016-2567
Published: 15 July 2016
View article titled, Abstract 2567: Characterizing histologic subtypes in lung cancer using principal component analysis
Journal Articles

Abstract 4610: Functional characterization of a multicancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148

Kevin M. Brown, Jun Fang, Jinping Jia, Zhaoming Wang, Matthew Makowski, Tongwu Zhang, Jason Hoskins, Jiyeon Choi, Younghun Han, Mingfeng Zhang, Mai Xu, Peter Kanetsky, Andresson Thorkell, Gloria M. Petersen, Katherine L. Nathanson, Christopher I. Amos, Maria T. Landi, Stephen J. Chanock, Michiel Vermeulen, Laufey T. Amundadottir
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4610.
https://doi.org/10.1158/1538-7445.AM2015-4610
Published: 01 August 2015
View article titled, Abstract 4610: Functional characterization of a multicancer risk locus on chr5p15.33 reveals regulation of <em>TERT</em> by ZNF148
Journal Articles

Abstract 4609: Risk loci in telomere structure and maintenance genes across five cancer types: GAME-ON Consortium

Sara Karami, Younghun Han, Fredrick R. Schumacher, Zsofia Kote-Jarai, Sara Lindstrom, John S. Witte, Iona Cheng, Shenying Fang, Jiali Han, Peter Kraft, Fengju Song, Rayjean J. Hung, James McKay, Stephen J. Chanock, Mala Pande, Angela Risch, Hongbing Shen, Christopher A. Haiman, Lisa Boardman, Cornelia M. Ulrich, Graham Casey, Ulrike Peters, Nilanjan Chatterjee, Brandon Pierce, Wei Zheng, Christopher I. Amos, Jennifer A. Doherty
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4609.
https://doi.org/10.1158/1538-7445.AM2015-4609
Published: 01 August 2015
View article titled, Abstract 4609: Risk loci in telomere structure and maintenance genes across five cancer types: GAME-ON Consortium
Journal Articles

Abstract 2174: Identification of genetic factors contributing to development of common cancers through tissue-specific protein interaction analysis

David C. Qian, Jinyoung Byun, Younghun Han, David J. Hunter, Brian E. Henderson, Rosalind Eeles, Christopher A. Haiman, Douglas F. Easton, Rayjean J. Hung, Christopher I. Amos
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2174.
https://doi.org/10.1158/1538-7445.AM2015-2174
Published: 01 August 2015
View article titled, Abstract 2174: Identification of genetic factors contributing to development of common cancers through tissue-specific protein interaction analysis
Journal Articles

Genetic Determinants for Promoter Hypermethylation in the Lungs of Smokers: A Candidate Gene-Based Study

Shuguang Leng, Christine A. Stidley, Yushi Liu, Christopher K. Edlund, Randall P. Willink, Younghun Han, Maria Teresa Landi, Michael Thun, Maria A. Picchi, Shannon E. Bruse, Richard E. Crowell, David Van Den Berg, Neil E. Caporaso, Christopher I. Amos, Jill M. Siegfried, Yohannes Tesfaigzi, Frank D. Gilliland, Steven A. Belinsky
Journal: Cancer Research
Cancer Res (2012) 72 (3): 707–715.
https://doi.org/10.1158/0008-5472.CAN-11-3194
Published: 31 January 2012
View article titled, Genetic Determinants for Promoter Hypermethylation in the Lungs of Smokers: A Candidate Gene-Based Study
Open the PDF for Genetic Determinants for Promoter Hypermethylation in the Lungs of Smokers: A Candidate Gene-Based Study in another window
Includes: Supplementary data
Journal Articles

Abstract LB-441: The genome wide gene-environment interaction analysis for asbestos exposure on lung cancer susceptibility

Sheng Wei, Li-e Wang, Michelle K. McHugh, Younghun Han, Christopher I. Amos, Margaret R. Spitz, Momiao Xiong, Qingyi Wei
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-441.
https://doi.org/10.1158/1538-7445.AM2011-LB-441
Published: 15 April 2011
View article titled, Abstract LB-441: The genome wide gene-environment interaction analysis for asbestos exposure on lung cancer susceptibility
Journal Articles

Abstract 889: An analysis of single nucleotide polymorphisms of 125 DNA repair genes in the Texas genome-wide association study of lung cancer with a replication for the XRCC4 SNPs

Hongping Yu, Hui Zhao, Li-E Wang, Younghun Han, Chen Wei V., Christopher I. Amos, Thorunn Rafnar, Patrick Sulem, Kari Stefansson, Maria Teresa Landi, Neil Caporaso, Demetrius Albanes, Michael Thun, James D. McKay, Paul Brennan, Yufei Wang, Richard S Houlston, Margaret R. Spitz, Qingyi Wei
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 889.
https://doi.org/10.1158/1538-7445.AM2011-889
Published: 15 April 2011
View article titled, Abstract 889: An analysis of single nucleotide polymorphisms of 125 DNA repair genes in the Texas genome-wide association study of lung cancer with a replication for the <em>XRCC4</em> SNPs
Journal Articles

Abstract 2849: A functional promoter variant (rs2075533 C>T) in TNFSF8 involved in apoptosis contributes to decreased risk of lung cancer — a finding from Texas lung cancer genome-wide association study

Sheng Wei, Jiangong Niu, Hui Zhao, Zhensheng Liu, Li-E Wang, Younghun Han, Christopher I. Amos, Margaret R. Spitz, Qingyi Wei
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2849.
https://doi.org/10.1158/1538-7445.AM10-2849
Published: 15 April 2010
View article titled, Abstract 2849: A functional promoter variant (rs2075533 C&gt;T) in <em>TNFSF</em>8 involved in apoptosis contributes to decreased risk of lung cancer — a finding from Texas lung cancer genome-wide association study