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Young Kwang Chae
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Journal Articles

Abstract 4113: Response to amivantamab, a bispecific EGF and MET receptor directed antibody, in a patient with an atypical EGFR mutated (G719X) non-small cell lung cancer (NSCLC) with leptomeningeal disease who progressed on osimertinib

Jinah Kim, Horyun Choi, Yeun Ho Lee, Leeseul Kim, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4113.
DOI: https://doi.org/10.1158/1538-7445.AM2022-4113
Published: 15 June 2022
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Abstract 4120: Acquired TPM3-NTRK1 fusion resistant to larotrectinib in a non-small cell lung cancer with EML4-ALK fusion progressed on lorlatinib

Horyun Choi, Jinah Kim, Yeun Ho Lee, Leeseul Kim, Na Hyun Kim, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4120.
DOI: https://doi.org/10.1158/1538-7445.AM2022-4120
Published: 15 June 2022
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Abstract 4121: Durable stable disease with nivolumab, PD-1 inhibitor, and subsequent bevacizumab, Anti-VEGF monoclonal antibody, in long standing recurrent respiratory papillomatosis with lung squamous cell carcinoma

Horyun Choi, Jinah Kim, Yeun Ho Lee, Leeseul Kim, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4121.
DOI: https://doi.org/10.1158/1538-7445.AM2022-4121
Published: 15 June 2022
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Abstract 5200: The incidence and risk factors of hyperprogressive disease(HPD) in non-small cell lung cancer(NSCLC) treated with immune checkpoint inhibitors(ICI)

Hyeonseon Kim, Yeun Ho Lee, Chiwoo Song, Leeseul Kim, Min Jeong Kim, Horyun Choi, Jinah Kim, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5200.
DOI: https://doi.org/10.1158/1538-7445.AM2022-5200
Published: 15 June 2022
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Abstract 1691: The landscape of intra-tumor heterogeneity (ITH) and its association with actionable mutation and blood tumor mutation burden (bTMB) in patients with non-small cell lung cancer (NSCLC) assessed by circulating tumor DNA (ctDNA)

Leeseul Kim, Yeun Ho Lee, Hye Sung Kim, Horyun Choi, Jinah Kim, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1691.
DOI: https://doi.org/10.1158/1538-7445.AM2022-1691
Published: 15 June 2022
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Journal Articles

Abstract 5785: Tumors with higher heterogeneity were associated with poorer survival outcome in early stage lung adenocarcinoma cancer patients with low tumor mutational burden

Stanislav Fridland, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5785.
DOI: https://doi.org/10.1158/1538-7445.AM2022-5785
Published: 15 June 2022
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Abstract 644: Deep learning-based H&E analyzer reveals distinct immune profiles and clinical outcomes among immune phenotypes in uterine corpus endometrial carcinoma

Horyun Choi, Leeseul Kim, Jinah Kim, Yeun Ho Lee, Hyung-Gyo Cho, Na Hyun Kim, Gahyun Gim, Sanghoon Song, Gahee Park, Soo Ick Cho, Sergio Pereira, Donggeun Yoo, Kyunghyun Paeng, Chan-Young Ock, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 644.
DOI: https://doi.org/10.1158/1538-7445.AM2022-644
Published: 15 June 2022
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Abstract 2722: Evaluation of in silico tools for variant classification in missense variants of solid cancer with actionable genetic targets

Chiwoo Song, Emma Yu, Ilene Hong, Grace Lee, Alice D. Lee, William Cheng, Eugene Kim, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2722.
DOI: https://doi.org/10.1158/1538-7445.AM2022-2722
Published: 15 June 2022
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Abstract 3343: Durable response to osimertinib monotherapy as first line treatment in stage IVB lung adenocarcinoma with atypical EGFR L747P mutation

Horyun Choi, Yeun Ho Lee, Jinah Kim, Leeseul Kim, Na Hyun Kim, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3343.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3343
Published: 15 June 2022
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Abstract 1985: Ipilimumab and nivolumab induced reactivation of hepatitis B (HBVr) in patient with metastatic squamous cell lung cancer

Leeseul Kim, Horyun Choi, Yeun Ho Lee, Jinah Kim, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1985.
DOI: https://doi.org/10.1158/1538-7445.AM2022-1985
Published: 15 June 2022
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Abstract 519: Hyperprogression in follicular thyroid cancer treated with combination immunotherapy

Yeun Ho Lee, Leeseul Kim, Myungwoo Nam, William Cheng, Won Kyung Hur, Jin Young Hwang, Yoonhee Choi, William H Bae, Eugene Kim, Heayoon Shauna Cho, Emma Yu, Chan Mi Jung, Christmann Low, Elena Vagia, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 519.
DOI: https://doi.org/10.1158/1538-7445.AM2021-519
Published: 01 July 2021
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Abstract 520: Potential role of serum proteome in predicting immune-related adverse events from immunotherapy in non-small cell lung cancer

Myungwoo Nam, Leeseul Kim, William Cheng, William H. Bae, Jin Young Hwang, Yoonhee Choi, Yeun Ho Lee, Won Kyung Hur, Chan Mi Jung, Heayoon S. Cho, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 520.
DOI: https://doi.org/10.1158/1538-7445.AM2021-520
Published: 01 July 2021
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Abstract 673: The role of mass spectrometry-based serum proteomics signatures in predicting clinical outcomes in cancer patients treated with immune check point inhibitors (ICI)

Yoonhee Choi, Jin Young Hwang, Won Kyung Hur, Myungwoo Nam, Leeseul Kim, Yeun Ho Lee, William Cheng, Eugene Kim, Emma Yu, Chan Mi Jung, William Han Bae, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 673.
DOI: https://doi.org/10.1158/1538-7445.AM2021-673
Published: 01 July 2021
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Abstract 626: The neoantigen and immune landscape of epithelial mesenchymal transition (EMT) low and high score serous ovarian cancers

Won Kyung Hur, Jin Young Hwang, Leeseul Kim, Myungwoo Nam, William H. Bae, Yoonhee Choi, Yeun Ho Lee, Heayoon S. Cho, Emma Yu, Chan Mi Jung, William Cheng, Eugene Kim, Christmann Low, Victor Wang, Jeff Chuang, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 626.
DOI: https://doi.org/10.1158/1538-7445.AM2021-626
Published: 01 July 2021
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Abstract 678: Exceptional response to PD-L1 inhibitor after radiation therapy in a patient with small cell neuroendocrine tumor of the prostate gland refractory to combination treatment with PD-1 and CTLA-4 inhibitors

Leeseul Kim, William Cheng, Yeun Ho Lee, Myungwoo Nam, Won Kyung Hur, Jin Young Hwang, Yoonhee Choi, William H Bae, Cyra Y. Kang, Heayoon Shauna Cho, Emma Yu, Chan Mi Jung, Eugene Kim, Christmann Low, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 678.
DOI: https://doi.org/10.1158/1538-7445.AM2021-678
Published: 01 July 2021
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Abstract 451: Immune landscape of endometrial carcinoma and its association with neoantigen landscape and TGF-β signaling pathway related genes mutation status

William H. Bae, Jin Young Hwang, Won Kyung Hur, Myungwoo Nam, Yoonhee Choi, Leeseul Kim, Yeun Ho Lee, William Cheng, Eugene Kim, Emma Yu, Chan Mi Jung, Heayoon S. Cho, Jeff Chuang, Victor Wang, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 451.
DOI: https://doi.org/10.1158/1538-7445.AM2021-451
Published: 01 July 2021
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Abstract 452: TGF-β signaling pathway-related gene mutations are associated with increased neoantigen counts, enhanced cytolytic activity, and improved survival outcomes in TP53-mutated endometrial carcinoma

William H. Bae, Jin Young Hwang, Won Kyung Hur, Myungwoo Nam, Yoonhee Choi, Leeseul Kim, Yeun Ho Lee, William Cheng, Eugene Kim, Emma Yu, Chan Mi Jung, Jeff Chuang, Victor Wang, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 452.
DOI: https://doi.org/10.1158/1538-7445.AM2021-452
Published: 01 July 2021
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Abstract 453: The neoantigen and immune landscape of low and high grade serous ovarian cancers

Won Kyung Hur, Jin Young Hwang, Leeseul Kim, Myungwoo Nam, William H. Bae, Yoonhee Choi, Yeun Ho Lee, William Cheng, Heayoon S. Cho, Emma Yu, Chan Mi Jung, Eugene Kim, Christmann Low, Victor Wang, Jeff Chuang, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 453.
DOI: https://doi.org/10.1158/1538-7445.AM2021-453
Published: 01 July 2021
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Abstract PO-003: CRESTONE – Clinical study of response to seribantumab in tumors with neuregulin-1 (NRG1) Fusions – A phase 2 study of the anti-HER3 mAb for advanced or metastatic solid tumors (NCT04383210)

Johanna C. Bendell, Kian-Huat Lim, Mark E. Burkard, Jessica J. Lin, Young Kwang Chae, Mark A. Socinski, Gazala Khan, Karen L. Reckamp, Shawn Leland, Douglas Plessinger, Lori Kunkel, Efrat Dotan, Gregory Otterson, Sai-Hong Ignatius Ou, Tejas Patil, John V. Heymach, Edward S. Kim
Journal: Cancer Research
Cancer Res (2020) 80 (22_Supplement): PO-003.
DOI: https://doi.org/10.1158/1538-7445.PANCA20-PO-003
Published: 13 November 2020
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Abstract 5076: Comprehensive deep learning analysis of H&E tissue phenomics reveals distinct immune landscape and transcriptomic enrichment profile among immune inflamed, excluded and desert subtypes in non-small cell lung cancer

Jonghanne Park, Chan-Young Ock, Kyunghyun Paeng, Sehhoon Park, Horyun Choi, Dongyup Lee, Gahyun Gim, Sukjoo Cho, Yoon La Choi, Se-Hoon Lee, Young Kwang Chae
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5076.
DOI: https://doi.org/10.1158/1538-7445.AM2020-5076
Published: 15 August 2020
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