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Journal Articles

Abstract 552: FGFR4 and CD276 dualtargeting CAR-T cells for treating rhabdomyosarcoma and other solid tumors

Meijie Tian, Adam Cheuk, David Milewski, Jun S. Wei, Hsien-Chao Chou, Yong Yean Kim, Young K. Song, Brad St. Croix, Mitchell Ho, Javed Khan
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 552.
DOI: https://doi.org/10.1158/1538-7445.AM2022-552
Published: 15 June 2022
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Journal Articles

Abstract 3581: Multi-omic analysis identifies mechanisms of resistance to CD19 CAR T-cell therapy in children with acute lymphoblastic leukemia

Katherine E. Masih, Rebecca Gardner, Hsien-Chao Chou, Abdalla Abdelmaksoud, Young K. Song, Luca Mariani, Vineela Gangalapudi, Berkley E. Gryder, Ashley Wilson, Serifat O. Adebola, Benjamin Z. Stanton, Chaoyu Wang, Xinyu Wen, Gregoire Altan-Bonnet, Michael C. Kelly, Jun S. Wei, Martha L. Bulyk, Michael C. Jensen, Rimas J. Orentas, Javed Khan
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3581.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3581
Published: 15 June 2022
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Journal Articles

Abstract LB-141: Increased epigenetic plasticity and tumor heterogeneity predict resistance to CD19 CAR T cell therapy in pre-treatment pediatric acute lymphoblastic leukemia

Katherine E. Masih, Abdalla Abdelmaksoud, David Milewski, Berkley E. Gryder, Rebecca Gardner, Ashley L. Wilson, Benjamin Z. Stanton, Young K. Song, Chaoyu Wang, Xinyu Wen, Serifat Adebola, Zachary Rae, Adam Cheuk, Justin Lack, Gregoire Altan-Bonnet, Michael Kelly, Jun Wei, Michael Jensen, Rimas J. Orentas
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): LB-141.
DOI: https://doi.org/10.1158/1538-7445.AM2020-LB-141
Published: 15 August 2020
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Journal Articles

Abstract 3445: Immuno-transcriptomic profiling identifies actionable genomic alterations in pediatric solid malignancies

Jun S. Wei, Andrew S. Brohl, Sivasish Sindiri, David Milewski, Young K. Song, Sushma Nagaraj, Vineela Gangalapudi, Xinyu Wen, Marc Ladanyi, Javed Khan
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3445.
DOI: https://doi.org/10.1158/1538-7445.AM2020-3445
Published: 15 August 2020
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Journal Articles

Abstract A13: Immunogenomic approaches to optimize immunotherapeutic targeting of neuroblastoma

Meijie Tian, Adam Tai-Chi Cheuk, Jeetendra Kumar, Young K. Song, Sivasish Sindiri, Nan Li, Christopher M. Dower, Mitchell Ho, Brad St. Croix, Javed Khan
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): A13.
DOI: https://doi.org/10.1158/1538-7445.PEDCA19-A13
Published: 15 July 2020
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Journal Articles

Abstract PR17: Immunogenomic landscape of pediatric solid malignancies

Jun S. Wei, Andrew S. Brohl, Sivasish Sindiri, Young K. Song, Sushma Najaraj, Vineela Gangalapudi, Xinyu Wen, Marc Ladanyi, Javed Khan
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): PR17.
DOI: https://doi.org/10.1158/1538-7445.PEDCA19-PR17
Published: 15 July 2020
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Abstract A11: A comprehensive and integrative omic analysis of multiply relapsed refractory pediatric pre-B cell acute lymphoblastic leukemia predicts response to CD19 CAR T-cell therapy

Katherine E. Masih, Rebecca Gardner, Berkley E. Gryder, Abdalla Abdelmaksoud, Ashley Wilson, Serifat Adebola, Benjamin Z. Stanton, Young K. Song, Justin Lack, Chaoyu Wang, Xinyu Wen, Zachary Rae, Adam Cheuk, Gregoire Altan-Bonnet, Michael Kelly, Jun S. Wei, Michael C. Jensen, Rimas J. Orentas, Javed Khan
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): A11.
DOI: https://doi.org/10.1158/1538-7445.PEDCA19-A11
Published: 15 July 2020
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Journal Articles

Abstract 3653: Immunogenomic landscape of pediatric solid malignancies

Jun S. Wei, Andrew S. Brohl, Young K. Song, Sushma Najaraj, Vineela Gangalapudi, Ashley Walton, Xinyu Wen, Marc Ladanyi, Javed Khan
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3653.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3653
Published: 01 July 2019
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Journal Articles

Abstract 1744: RNAseq identified immune signatures associated with adverse outcome in high-risk neuroblastoma

Jun S. Wei, Shile Zhang, Igor Kuznetsov, Young K. Song, Shahab Asgharzadeh, Sivasish Sindiri, Xinyu Wen, Rajesh Patidar, Jaime M. Guidry Auvil, Daniela S. Gerhard, Robert Seeger, John M. Maris, Javed Khan
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1744.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1744
Published: 01 July 2017
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Journal Articles

Abstract 126: The transcriptome landscape of high-risk neuroblastoma

Jun S. Wei, Shile Zhang, Young K. Song, Shahab Asgharzadeh, Sivasish Sindiri, Xinyu Wen, Rajesh Patidar, Jaime M. Guidry Auvil, Daniela S. Gerhard, Robert Seeger, John M. Maris, Javed Khan
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 126.
DOI: https://doi.org/10.1158/1538-7445.AM2016-126
Published: 15 July 2016
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Journal Articles

Abstract A25: Reprogramming RAS-driven rhabdomyosarcoma via MEK inhibition

Marielle E. Yohe, Berkley E. Gryder, Jack F. Shern, Young K. Song, Hongling Liao, Hsein-Chao Chou, Sivasish Sindiri, Arnulfo Mendoza, Xiaohu Zhang, Rajarashi Guha, Diana C. Haines, James P. Madigan, Jun S. Wei, Marc Ferrer, Craig J. Thomas, Javed Khan
Journal: Cancer Research
Cancer Res (2016) 76 (5_Supplement): A25.
DOI: https://doi.org/10.1158/1538-7445.PEDCA15-A25
Published: 04 April 2016
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Journal Articles

Abstract B31: Combined siRNA and small molecule screening identifies Aurora B kinase as an effective target in MYCN-driven neuroblastoma

Dominik Bogen, Jun S. Wei, David O. Azorsa, Pinar Ormanoglu, Eugen Buehler, Rajarshi Guha, Jonathan M. Keller, Lesley A. Mathews Griner, Marc Ferrer, Young K. Song, Hongling Liao, Arnulfo Mendoza, Berkley E. Gryder, Sivasish Sindri, Jianbin He, Xinyu Wen, Xinyu Wen, Shile Zhang, John F. Shern, Marielle E. Yohe, Sabine Taschner-Mandl, Jason Shohet, Craig J. Thomas, Scott E. Martin, Peter F. Ambros, Javed Khan
Journal: Cancer Research
Cancer Res (2016) 76 (5_Supplement): B31.
DOI: https://doi.org/10.1158/1538-7445.PEDCA15-B31
Published: 04 April 2016
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Journal Articles

Abstract 3218: Transcriptome characterization by RNA sequencing identifies molecular and clinical subgroups in high risk neuroblastoma

Shile Zhang, Jun S. Wei, Rajesh Patidar, Young K. Song, Sivasish Sindiri, Xinyu Wen, Shahab Asgharzadeh, Robert C. Seeger, John M. Maris, Jamie M. Guidry Auvil, Daniela S. Gerhard, Javed Khan
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3218.
DOI: https://doi.org/10.1158/1538-7445.AM2015-3218
Published: 01 August 2015
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Journal Articles

Abstract 3882: Clinical exome and transcriptome sequencing for identification of actionable cancer targets: A pilot study for children and young adults with relapsed or refractory solid tumors

Wen-I Chang, Andrew S. Brohl, Rajesh Patidar, Jack F. Shern, Jun S. Wei, Young K. Song, Hongling Liao, Jimmy Lin, Sivasish Sindiri, Li Chen, Berkley Gryder, Marielle E. Yohe, Shile Zhang, Melinda S. Merchant, Brigitte C. Widemann, Javed Khan
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3882.
DOI: https://doi.org/10.1158/1538-7445.AM2015-3882
Published: 01 August 2015
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Journal Articles

Abstract A12: Systematic identification of germline mutations in rhabdomyosarcoma and neuroblastoma using massively paralleled sequencing

Jun S. Wei, Rajesh Patidar, John Shern, Shile Zhang, Trevor Pugh, Sharon J. Diskin, Sivasish Sindiri, Young K. Song, Hongling Liao, Xinyu Wen, Jianjun Wang, Stephen X. Skapek, James R. Anderson, Frederic G. Barr, Robert C. Seeger, John M. Maris, Douglas Hawkins, Javed Khan
Journal: Cancer Research
Cancer Res (2014) 74 (20_Supplement): A12.
DOI: https://doi.org/10.1158/1538-7445.PEDCAN-A12
Published: 09 October 2014
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Abstract 5081: Systematic identification of germline mutations in rhabdomyosarcoma and neuroblastoma using massively paralleled sequencing

Jun S. Wei, Rajesh Patidar, John Shern, Shile Zhang, Trevor Pugh, Sharon J. Diskin, Sivasish Sindiri, Young K. Song, Hongling Liao, Xinyu Wen, Jianjun Wang, Stephen X. Skapek, James R. Anderson, Frederic G. Barr, Robert C. Seeger, John M. Maris, Douglas S. Hawkins, Javed Khan
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5081.
DOI: https://doi.org/10.1158/1538-7445.AM2014-5081
Published: 01 October 2014
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Journal Articles

Abstract 3413: A genetic analysis of splicing in neuroblastoma identifies opposing functions for FUBP1 splice variants in MYC regulation

Justin Chen, Christopher S. Hackett, Shile Zhang, Young K. Song, Annette Molinaro, David A. Quigley, Allan Balmain, William C. Gustafson, Terry A. Van Dyke, Pui-Yan Kwok, Javed Khan, William A. Weiss
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3413.
DOI: https://doi.org/10.1158/1538-7445.AM2014-3413
Published: 01 October 2014
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Journal Articles

Abstract 2619: Whole genome and transcriptome sequencing identifies an activating mutation of LPAR1 in a patient with metastatic neuroblastoma.

Jun S. Wei, Peter Johansson, Li Chen, Young K. Song, Catherine Tolman, Samuel Li, Laura Hurd, Rajesh Patidar, Xinyu Wen, Thomas C. Badgett, Adam Cheuk, Jean-Claude Marshall, Patricia Steeg, José Pedro Vaqué Díez, J Silvio Gutkind, Javed Khan
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2619.
DOI: https://doi.org/10.1158/1538-7445.AM2013-2619
Published: 15 April 2013
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Abstract 4398: Synthetic lethal siRNA screening to identify novel combinational therapies with Topotecan in neuroblastoma.

Dominik Bogen, Eugen C. Buehler, Pinar Tuzmen, Rajesh Patidar, David Azorsa, Young K. Song, Hongling Liao, Catherine A. Tolman, Xinyu Wen, Jianbin N. He, Scott E. Martin, Jun S. Wei, Javed Khan
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4398.
DOI: https://doi.org/10.1158/1538-7445.AM2013-4398
Published: 15 April 2013
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Journal Articles

Abstract 3161: Massively parallel transcriptome sequencing in neuroblastoma reveals specific mRNA splicing patterns controlled by RNA binding splicing factors.

Shile Zhang, Tom Badgett, Jun Wei, Young K. Song, Dominik Bogen, Peter Johansson, Catherine Tolman, Jianbin He, Xinyu Wen, Zhihui Liu, Carol Thiele, Javed Khan
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3161.
DOI: https://doi.org/10.1158/1538-7445.AM2013-3161
Published: 15 April 2013
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