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Abstract 1875: PBK expression promotes the aggressive phenotypes of mesothelioma

Kazumi Hori, Ichidai Tanaka, Tatsuhiro Sato, Mika Sato, Yuta Kodama, Hideyuki Itoigawa, Yuichi Abe, Taketo Kato, Ayumu Taguchi, Mitsuo Sato, Yoshitaka Sekido, Toyofumi Fengshi Yoshikawa, Makoto Ishii

Cancer Res (2025) 85 (8_Supplement_1): 1875.

https://doi.org/10.1158/1538-7445.AM2025-1875

Published: 21 April 2025

View articletitled, Abstract 1875: PBK expression promotes the aggressive phenotypes of mesothelioma

Journal Articles

Abstract 1046: Statin inhibits malignant mesothelioma cell growth by inactivating YAP1

Kosuke Tanaka, Taketo Kato, Akihiro Matsushita, Hiromi Furuta, Yuko Murakami, Hirotaka Osada, Yoshitaka Sekido

Cancer Res (2016) 76 (14_Supplement): 1046.

https://doi.org/10.1158/1538-7445.AM2016-1046

Published: 15 July 2016

View articletitled, Abstract 1046: Statin inhibits malignant mesothelioma cell growth by inactivating YAP1

Journal Articles

Chromatin Regulator PRC2 Is a Key Regulator of Epigenetic Plasticity in Glioblastoma

Atsushi Natsume, Motokazu Ito, Keisuke Katsushima, Fumiharu Ohka, Akira Hatanaka, Keiko Shinjo, Shinya Sato, Satoru Takahashi, Yuta Ishikawa, Ichiro Takeuchi, Hiroki Shimogawa, Motonari Uesugi, Hideyuki Okano, Seung U. Kim, Toshihiko Wakabayashi, Jean-Pierre J. Issa, Yoshitaka Sekido, Yutaka Kondo

Cancer Res (2013) 73 (14): 4559–4570.

https://doi.org/10.1158/0008-5472.CAN-13-0109

Published: 15 July 2013

View articletitled, Chromatin Regulator PRC2 Is a Key Regulator of Epigenetic Plasticity in Glioblastoma

Includes: Supplementary data

Journal Articles

Abstract 4313: A LIM protein ajuba suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade.

Ichidai Tanaka, Hirotaka Osada, Makiko Fujii, Yoshitaka Sekido

Cancer Res (2013) 73 (8_Supplement): 4313.

https://doi.org/10.1158/1538-7445.AM2013-4313

Published: 15 April 2013

View articletitled, Abstract 4313: A LIM protein ajuba suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade.

Journal Articles

EGFR-TKI Resistance Due to BIM Polymorphism Can Be Circumvented in Combination with HDAC Inhibition

Takayuki Nakagawa, Shinji Takeuchi, Tadaaki Yamada, Hiromichi Ebi, Takako Sano, Shigeki Nanjo, Daisuke Ishikawa, Mitsuo Sato, Yoshinori Hasegawa, Yoshitaka Sekido, Seiji Yano

Cancer Res (2013) 73 (8): 2428–2434.

https://doi.org/10.1158/0008-5472.CAN-12-3479

Published: 15 April 2013

View articletitled, EGFR-TKI Resistance Due to BIM Polymorphism Can Be Circumvented in Combination with HDAC Inhibition

Includes: Supplementary data

Journal Articles

Abstract 5003: Integrated analysis of genetic and epigenetic alterations reveals CpG island methylator phenotype associated with distinct clinical characters of lung adenocarcinoma

Keiko Shinjo, Yasuyuki Okamoto, Ichiro Takeuchi, Makiko Fujii, Hirotaka Osada, Noriyasu Usami, Hidemi Ito, Toyoaki Hida, Yoshitaka Sekido, Yutaka Kondo

Cancer Res (2012) 72 (8_Supplement): 5003.

https://doi.org/10.1158/1538-7445.AM2012-5003

Published: 15 April 2012

View articletitled, Abstract 5003: Integrated analysis of genetic and epigenetic alterations reveals CpG island methylator phenotype associated with distinct clinical characters of lung adenocarcinoma

Journal Articles

Abstract 3082: TGF-β synergistically stimulates malignant mesothelioma growth with defects in the Hippo pathway by inducing CTGF expression

Makiko Fujii, Takeshi Toyoda, Hayao Nakanishi, Yasushi Yatabe, Ayuko Sato, Yasue Matsudaira, Hidemi Ito, Hideki Murakami, Yutaka Kondo, Eisaku Kondo, Tohru Tsujimura, Toyoaki Hida, Hirotaka Osada, Yoshitaka Sekido

Cancer Res (2012) 72 (8_Supplement): 3082.

https://doi.org/10.1158/1538-7445.AM2012-3082

Published: 15 April 2012

View articletitled, Abstract 3082: TGF-β synergistically stimulates malignant mesothelioma growth with defects in the Hippo pathway by inducing CTGF expression

Journal Articles

Abstract 3135: Epigenetic regulation of miR-1275 through histone H3 lysine 27 trimethylation during human glioma stem-like cell differentiation

Keisuke Katsushima, Keiko Shinjo, Fumiharu Ohka, Makiko Fujii, Hirotaka Osada, Yoshitaka Sekido, Atsushi Natsume, Yutaka Kondo

Cancer Res (2012) 72 (8_Supplement): 3135.

https://doi.org/10.1158/1538-7445.AM2012-3135

Published: 15 April 2012

View articletitled, Abstract 3135: Epigenetic regulation of miR-1275 through histone H3 lysine 27 trimethylation during human glioma stem-like cell differentiation

Journal Articles

miR-375 Is Activated by ASH1 and Inhibits YAP1 in a Lineage-Dependent Manner in Lung Cancer

Eri Nishikawa, Hirotaka Osada, Yasumasa Okazaki, Chinatsu Arima, Shuta Tomida, Yoshio Tatematsu, Ayumu Taguchi, Yukako Shimada, Kiyoshi Yanagisawa, Yasushi Yatabe, Shinya Toyokuni, Yoshitaka Sekido, Takashi Takahashi

Cancer Res (2011) 71 (19): 6165–6173.

https://doi.org/10.1158/0008-5472.CAN-11-1020

Published: 29 September 2011

View articletitled, miR-375 Is Activated by ASH1 and Inhibits YAP1 in a Lineage-Dependent Manner in Lung Cancer

Includes: Supplementary data

Journal Articles

Abstract 718: Acquired epithelial-mesenchymal transition like feature in an EGFR-mutant lung cancer cell line with acquired resistance to erlotinib

Kenichi Suda, Kenji Tomizawa, Hirotaka Osada, Yoshitaka Sekido, Yasushi Yatabe, Tetsuya Mitsudomi

Cancer Res (2011) 71 (8_Supplement): 718.

https://doi.org/10.1158/1538-7445.AM2011-718

Published: 15 April 2011

View articletitled, Abstract 718: Acquired epithelial-mesenchymal transition like feature in an EGFR-mutant lung cancer cell line with acquired resistance to erlotinib

Journal Articles

Abstract 3992: Roles of ASH1-miR-375 pathway in development of lung cancers with neuroendocrine features

Osada Hirotaka, Eri Nishikawa, Chinatsu Arima, Yasumasa Okazaki, Shuta Tomida, Yoshio Tatematsu, Ayumu Taguchi, Yukako Shimada, Kiyoshi Yanagisawa, Shinya Toyokuni, Yoshitaka Sekido, Takashi Takahashi

Cancer Res (2011) 71 (8_Supplement): 3992.

https://doi.org/10.1158/1538-7445.AM2011-3992

Published: 15 April 2011

View articletitled, Abstract 3992: Roles of ASH1-miR-375 pathway in development of lung cancers with neuroendocrine features

Journal Articles

Abstract 4811: Analysis of epigenetic alterations in mice with humanized liver after hepatitis virus infection

Yasuyuki Okamoto, Keiko Shinjo, Yasuhito Tanaka, Makiko Fujii, Hideki Murakami, Hirotaka Osada, Hiromi Kataoka, Takashi Joh, Yoshitaka Sekido, Yutaka Kondo

Cancer Res (2011) 71 (8_Supplement): 4811.

https://doi.org/10.1158/1538-7445.AM2011-4811

Published: 15 April 2011

View articletitled, Abstract 4811: Analysis of epigenetic alterations in mice with humanized liver after hepatitis virus infection

Journal Articles

Abstract 61: Integrated analysis of genetic and epigenetic alterations reveals CpG island methylator phenotype associated with clinical outcome of lung adenocarcinoma

Keiko Shinjo, Yutaka Kondo, Yasuyuki Okamoto, Toshihiko Yokoyama, Noriyasu Usami, Makiko Fujii, Hideki Murakami, Hirotaka Osada, Yoshitaka Sekido

Cancer Res (2011) 71 (8_Supplement): 61.

https://doi.org/10.1158/1538-7445.AM2011-61

Published: 15 April 2011

View articletitled, Abstract 61: Integrated analysis of genetic and epigenetic alterations reveals CpG island methylator phenotype associated with clinical outcome of lung adenocarcinoma

Journal Articles

Abstract 1657: A pivotal role for epithelial cell adhesion molecule (EpCAM) in survival of lung cancer cells

Tetsunari Hase, Mitsuo Sato, Kenya Yoshida, Yoshihiro Takeyama, Momen Elshazley, Yoshitaka Sekido, Adi F. Gazdar, John D. Minna, Masashi Kondo, Yoshinori Hasegawa

Cancer Res (2011) 71 (8_Supplement): 1657.

https://doi.org/10.1158/1538-7445.AM2011-1657

Published: 15 April 2011

View articletitled, Abstract 1657: A pivotal role for epithelial cell adhesion molecule (EpCAM) in survival of lung cancer cells

Journal Articles

LATS2 Is a Tumor Suppressor Gene of Malignant Mesothelioma

Hideki Murakami, Tetsuya Mizuno, Tetsuo Taniguchi, Makiko Fujii, Futoshi Ishiguro, Takayuki Fukui, Shinya Akatsuka, Yoshitsugu Horio, Toyoaki Hida, Yutaka Kondo, Shinya Toyokuni, Hirotaka Osada, Yoshitaka Sekido

Cancer Res (2011) 71 (3): 873–883.

https://doi.org/10.1158/0008-5472.CAN-10-2164

Published: 01 February 2011

View articletitled, LATS2 Is a Tumor Suppressor Gene of Malignant Mesothelioma

Includes: Supplementary data

Journal Articles

Abstract 629: Hepatocyte growth factor induces resistance to an irreversible epidermal growth factor receptor inhibitor in EGFR-T790M mutant lung cancer

Tadaaki Yamada, Kunio Matsumoto, Ivan Shterev Donev, Yoshitaka Sekido, Yasuhiko Nishioka, Saburo Sone, Seiji Yano

Cancer Res (2010) 70 (8_Supplement): 629.

https://doi.org/10.1158/1538-7445.AM10-629

Published: 15 April 2010

View articletitled, Abstract 629: Hepatocyte growth factor induces resistance to an irreversible epidermal growth factor receptor inhibitor in EGFR-T790M mutant lung cancer

Journal Articles

Abstract 2302: Knockdown of ZEB1, a master epithelial-to-mesenchymal transition (EMT) inducing gene, suppresses growth of pleural mesothelioma cell lines

Mihoko Horio, Mitsuo Sato, Yoshihiro Takeyama, Tetsunari Hase, Kenya Yoshida, Yoshitaka Sekido, Masashi Kondo, Yoshinori Hasegawa

Cancer Res (2010) 70 (8_Supplement): 2302.

https://doi.org/10.1158/1538-7445.AM10-2302

Published: 15 April 2010

View articletitled, Abstract 2302: Knockdown of ZEB1, a master epithelial-to-mesenchymal transition (EMT) inducing gene, suppresses growth of pleural mesothelioma cell lines

Journal Articles

Abstract 2295: Knockdown of ZEB1, a master EMT gene, suppresses anchorage-independent cell growth of lung cancer cells

Mitsuo Sato, Yoshihiro Takeyama, Mihoko Horio, Tetsunari Hase, Kenya Yoshida, Harunori Nakashima, Naozumi Hashimoto, Yoshitaka Sekido, Adi F. Gazdar, John D. Minna, Masashi Kondo, Yoshinori Hasegawa

Cancer Res (2010) 70 (8_Supplement): 2295.

https://doi.org/10.1158/1538-7445.AM10-2295

Published: 15 April 2010

View articletitled, Abstract 2295: Knockdown of ZEB1, a master EMT gene, suppresses anchorage-independent cell growth of lung cancer cells

Journal Articles

Epigenetic Profiles Distinguish Malignant Pleural Mesothelioma from Lung Adenocarcinoma

Cancer Res (2009) 69 (23): 9073–9082.

https://doi.org/10.1158/0008-5472.CAN-09-1595

Published: 30 November 2009

View articletitled, Epigenetic Profiles Distinguish Malignant Pleural Mesothelioma from Lung Adenocarcinoma

Includes: Supplementary data

Journal Articles

Abstract #5165: Comprehensive methylation analysis reveals characteristic methylation profiling of CpG island methylator phenotype-negative colorectal cancers in distal colon

Yutaka Kondo, Byonggu An, Keiko Shinjo, Yasuyuki Okamoto, Hidenori Yokoyama, Kenji Yamao, Takashi Hirai, Yasushi Yatabe, Makiko Fujii, Hideki Murakami, Hirotaka Osada, Lanlan Shen, Jean-Pierre Issa, Yoshitaka Sekido

Cancer Res (2009) 69 (9_Supplement): 5165.

Published: 01 May 2009

View articletitled, Abstract #5165: Comprehensive methylation analysis reveals characteristic methylation profiling of CpG island methylator phenotype-negative colorectal cancers in distal colon

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Abstract 1875: PBK expression promotes the aggressive phenotypes of mesothelioma

Abstract 1046: Statin inhibits malignant mesothelioma cell growth by inactivating YAP1

Chromatin Regulator PRC2 Is a Key Regulator of Epigenetic Plasticity in Glioblastoma

Abstract 4313: A LIM protein ajuba suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade.

EGFR-TKI Resistance Due to BIM Polymorphism Can Be Circumvented in Combination with HDAC Inhibition

Abstract 5003: Integrated analysis of genetic and epigenetic alterations reveals CpG island methylator phenotype associated with distinct clinical characters of lung adenocarcinoma

Abstract 3082: TGF-β synergistically stimulates malignant mesothelioma growth with defects in the Hippo pathway by inducing CTGF expression

Abstract 3135: Epigenetic regulation of miR-1275 through histone H3 lysine 27 trimethylation during human glioma stem-like cell differentiation

miR-375 Is Activated by ASH1 and Inhibits YAP1 in a Lineage-Dependent Manner in Lung Cancer

Abstract 718: Acquired epithelial-mesenchymal transition like feature in an EGFR-mutant lung cancer cell line with acquired resistance to erlotinib

Abstract 3992: Roles of ASH1-miR-375 pathway in development of lung cancers with neuroendocrine features

Abstract 4811: Analysis of epigenetic alterations in mice with humanized liver after hepatitis virus infection

Abstract 61: Integrated analysis of genetic and epigenetic alterations reveals CpG island methylator phenotype associated with clinical outcome of lung adenocarcinoma

Abstract 1657: A pivotal role for epithelial cell adhesion molecule (EpCAM) in survival of lung cancer cells

LATS2 Is a Tumor Suppressor Gene of Malignant Mesothelioma

Abstract 629: Hepatocyte growth factor induces resistance to an irreversible epidermal growth factor receptor inhibitor in EGFR-T790M mutant lung cancer

Abstract 2302: Knockdown of ZEB1, a master epithelial-to-mesenchymal transition (EMT) inducing gene, suppresses growth of pleural mesothelioma cell lines

Abstract 2295: Knockdown of ZEB1, a master EMT gene, suppresses anchorage-independent cell growth of lung cancer cells

Epigenetic Profiles Distinguish Malignant Pleural Mesothelioma from Lung Adenocarcinoma

Abstract #5165: Comprehensive methylation analysis reveals characteristic methylation profiling of CpG island methylator phenotype-negative colorectal cancers in distal colon

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