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Journal Articles

Abstract 5847: A histone deacetylase inhibitor OBP-801 and eribulin synergistically inhibit the growth with apoptosis in triple-negative breast cancer cells

Hisako Ono, Yoshihiro Sowa, Yosuke Iizumi, Mano Horinaka, Tetsuya Taguchi, Toshiyuki Sakai

Cancer Res (2018) 78 (13_Supplement): 5847.

https://doi.org/10.1158/1538-7445.AM2018-5847

Published: 01 July 2018

View article titled, Abstract 5847: A histone deacetylase inhibitor OBP-801 and eribulin synergistically inhibit the growth with apoptosis in triple-negative breast cancer cells

Journal Articles

Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity

Nobuya Ishii, Naoki Harada, Eric W. Joseph, Kazuhiro Ohara, Takaaki Miura, Hiroshi Sakamoto, Yutaka Matsuda, Yasushi Tomii, Yukako Tachibana-Kondo, Hitoshi Iikura, Toshihiro Aoki, Nobuo Shimma, Mikio Arisawa, Yoshihiro Sowa, Poulikos I. Poulikakos, Neal Rosen, Yuko Aoki, Toshiyuki Sakai

Cancer Res (2013) 73 (13): 4050–4060.

https://doi.org/10.1158/0008-5472.CAN-12-3937

Published: 30 June 2013

View article titled, Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity

Includes: Supplementary data

Journal Articles

Abstract 242: Anti-obesity drugorlistat enhances sensitivity toTRAIL by two different pathways inhormone-refractory prostate cancer cells

Jun Fujiwara, Yoshihiro Sowa, Mano Horinaka, Makoto Koyama, Miki Wakada, Tsuneharu Miki, Toshiyuki Sakai

Cancer Res (2012) 72 (8_Supplement): 242.

https://doi.org/10.1158/1538-7445.AM2012-242

Published: 15 April 2012

View article titled, Abstract 242: Anti-obesity drugorlistat enhances sensitivity toTRAIL by two different pathways inhormone-refractory prostate cancer cells

Journal Articles

Abstract 3585: Antitumor activities of JTP-74057 (GSK1120212), a novel MEK1/2 inhibitor, on colorectal cancer cell lines in vitro and in vivo

Takayuki Yamaguchi, Reina Kakefuda, Nobuyuki Tajima, Yoshihiro Sowa, Toshiyuki Sakai

Cancer Res (2011) 71 (8_Supplement): 3585.

https://doi.org/10.1158/1538-7445.AM2011-3585

Published: 15 April 2011

View article titled, Abstract 3585: Antitumor activities of JTP-74057 (GSK1120212), a novel MEK1/2 inhibitor, on colorectal cancer cell lines in vitro and in vivo

Journal Articles

Abstract 3606: CH5126766 is a novel allosteric inhibitor of MEK that prevents its phosphorylation by RAF

Nobuya Ishii, Naoki Harada, Hiroshi Sakamoto, Yutaka Matsuda, Yasushi Tomii, Yukako Tachibana-Kondo, Takaaki Miura, Kazuhiro Ohara, Hitoshi Iikura, Toshihiro Aoki, Nobuo Shimma, Mikio Arisawa, Eric Joseph, Poulikos Poulikakos, Yoshihiro Sowa, Neal Rosen, Yuko Aoki, Toshiyuki Sakai

Cancer Res (2011) 71 (8_Supplement): 3606.

https://doi.org/10.1158/1538-7445.AM2011-3606

Published: 15 April 2011

View article titled, Abstract 3606: CH5126766 is a novel allosteric inhibitor of MEK that prevents its phosphorylation by RAF

Journal Articles

Abstract 606: Expression and role of high mobility group protein AT-hook 1 (HMGA1) in human renal cell carcinoma

Natsuki Takaha, Ichiro Takeuchi, Yoshihiro Sowa, Yasunori Kimura, Terukazu Nakamura, Fumiya Hongo, Kazuya Mikami, Akihiro Kawauchi, Tsuneharu Miki

Cancer Res (2011) 71 (8_Supplement): 606.

https://doi.org/10.1158/1538-7445.AM2011-606

Published: 15 April 2011

View article titled, Abstract 606: Expression and role of high mobility group protein AT-hook 1 (HMGA1) in human renal cell carcinoma

Journal Articles

Abstract 5415: Histone deacetylase inhibitors and 15-deoxy-Δ^12,14-prostaglandin J₂ synergistically induce apoptosis

Makoto Koyama, Yasuyuki Izutani, Ahmed E. Goda, Taka-aki Matsui, Mano Horinaka, Mitsuhiro Tomosugi, Jun Fujiwara, Yoshitaka Nakamura, Miki Wakada, Shingo Yogosawa, Yoshihiro Sowa, Toshiyuki Sakai

Cancer Res (2010) 70 (8_Supplement): 5415.

https://doi.org/10.1158/1538-7445.AM10-5415

Published: 15 April 2010

View article titled, Abstract 5415: Histone deacetylase inhibitors and 15-deoxy-Δ12,14-prostaglandin J2 synergistically induce apoptosis

Journal Articles

Abstract 2560: Cyclin-dependent kinase inhibitor SU9516 enhances sensitivity to methotrexate in human T-cell Jurkat cells

Hitoji Uchiyama, Yoshihiro Sowa, Miki Wakada, Mayumi Yogosawa, Ryoko Nakanishi, Mano Horinaka, Chihiro Shimazaki, Masafumi Taniwaki, Toshiyuki Sakai

Cancer Res (2010) 70 (8_Supplement): 2560.

https://doi.org/10.1158/1538-7445.AM10-2560

Published: 15 April 2010

View article titled, Abstract 2560: Cyclin-dependent kinase inhibitor SU9516 enhances sensitivity to methotrexate in human T-cell Jurkat cells

Journal Articles

Genistein induces gadd45 gene and G2/M cell cycle arrest in the DU145 human prostate cancer cell line

Teruki Oki, Yoshihiro Sowa, Tohru Hirose, Nobumasa Takagaki, Ryoko Nakanishi, Motohiro Kanazawa, Yoshiko Satomi, Hoyoku Nishino, Tsuneharu Miki, Toshiyuki Sakai

Cancer Res (2005) 65 (9_Supplement): 574–575.

Published: 01 May 2005

View article titled, Genistein induces gadd45 gene and G2/M cell cycle arrest in the DU145 human prostate cancer cell line

Journal Articles

Class I histone deacetylases in intestinal epithelial cell maturation and transformation

Andrew J. Wilson, Do-Sun Byun, Diego Arango, Yoshihiro Sowa, Kaitlin L’Italien, Lucas B. Murray, Leonard H. Augenlicht, John M. Mariadason

Cancer Res (2005) 65 (9_Supplement): 436–437.

Published: 01 May 2005

View article titled, Class I histone deacetylases in intestinal epithelial cell maturation and transformation

Journal Articles

Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitor

Johanna S. Ungerstedt, Yoshihiro Sowa, Weisheng Xu, Yufang Shao, Milos Dokmanovic, Gisela Perez, Lang Ngo, Arne Holmgren*, Xuejun Jiang, Paul A. Marks

Cancer Res (2005) 65 (9_Supplement): 772.

Published: 01 May 2005

View article titled, Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitor

Journal Articles

CDK profiling of gastrointestinal carcinoma tissues.

Hideki Ishihara, Tomokazu Yoshida, Yuko Kawasaki, Hironori Kobayashi, Masatoshi Yamasaki, Satoshi Nakayama, Erika Miki, Kei-Ichiro Shohmi, Tomoko Matsushima, Sachiyo Tada, Masakatsu Morita, Yoko Hino, Jun Kamiyama, Yoshihiro Sowa, Yasunari Tsuchihashi, Hisakazu Yamagishi, Toshiyuki Sakai

Cancer Res (2004) 64 (7_Supplement): 844–845.

Published: 01 April 2004

View article titled, CDK profiling of gastrointestinal carcinoma tissues.

Journal Articles

Sp3, but not Sp1, Mediates the Transcriptional Activation of the p21/WAF1/Cip1 Gene Promoter by Histone Deacetylase Inhibitor

Yoshihiro Sowa, Tetsuro Orita, Sachie Minamikawa-Hiranabe, Takakazu Mizuno, Hitoshi Nomura, Toshiyuki Sakai

Cancer Res (1999) 59 (17): 4266–4270.

Published: 01 September 1999

View article titled, Sp3, but not Sp1, Mediates the Transcriptional Activation of the p21/WAF1/Cip1 Gene Promoter by Histone Deacetylase Inhibitor

Journal Articles

Retinoblastoma Binding Factor 1 Site in the Core Promoter Region of the Human RB Gene Is Activated by hGABP/E4TF1

Yoshihiro Sowa, Yuzuru Shiio, Tsuyoshi Fujita, Takuji Matsumoto, Yusuke Okuyama, Daishiro Kato, Jun-ichiro Inoue, Jun-ichi Sawada, Masahide Goto, Hajime Watanabe, Hiroshi Handa, Toshiyuki Sakai

Cancer Res (1997) 57 (15): 3145–3148.

Published: 01 August 1997

View article titled, Retinoblastoma Binding Factor 1 Site in the Core Promoter Region of the Human RB Gene Is Activated by hGABP/E4TF1

NARROW

Abstract 5847: A histone deacetylase inhibitor OBP-801 and eribulin synergistically inhibit the growth with apoptosis in triple-negative breast cancer cells

Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity

Abstract 242: Anti-obesity drugorlistat enhances sensitivity toTRAIL by two different pathways inhormone-refractory prostate cancer cells

Abstract 3585: Antitumor activities of JTP-74057 (GSK1120212), a novel MEK1/2 inhibitor, on colorectal cancer cell lines in vitro and in vivo

Abstract 3606: CH5126766 is a novel allosteric inhibitor of MEK that prevents its phosphorylation by RAF

Abstract 606: Expression and role of high mobility group protein AT-hook 1 (HMGA1) in human renal cell carcinoma

Abstract 5415: Histone deacetylase inhibitors and 15-deoxy-Δ^12,14-prostaglandin J₂ synergistically induce apoptosis

Abstract 2560: Cyclin-dependent kinase inhibitor SU9516 enhances sensitivity to methotrexate in human T-cell Jurkat cells

Genistein induces gadd45 gene and G2/M cell cycle arrest in the DU145 human prostate cancer cell line

Class I histone deacetylases in intestinal epithelial cell maturation and transformation

Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitor

CDK profiling of gastrointestinal carcinoma tissues.

Sp3, but not Sp1, Mediates the Transcriptional Activation of the p21/WAF1/Cip1 Gene Promoter by Histone Deacetylase Inhibitor

Retinoblastoma Binding Factor 1 Site in the Core Promoter Region of the Human RB Gene Is Activated by hGABP/E4TF1

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