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Yongkai Mo
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Journal Articles

Abstract 2515: Aberrant expression of CSF1R in melanoma is driven through an endogenous viral promoter and it contributes to malignant growth and BRAF-inhibitor resistance

Orsolya Giricz, Yongkai Mo, Kimberly B. Dahlman, Xiomaris M. Cotto-Rios, Chiara Vardabasso, Hoa Nguyen, Bernice Matusow, Matthias Bartenstein, Veronika Polishchuck-Lee, Douglas B. Johnson, Tushar B. Bhagat, Rafe Shellooe, Elizabeth Burton, Gaston Habets, John M. Greally, Yiting Yu, Gideon Bollag, Paraic A. Kenny, Kith Pradhan, E. Richard Stanley, Emily Bernstein, Evripidis Gavathiotis, Brian L. West, Jeffrey A. Sosman, Amit Verma
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2515.
https://doi.org/10.1158/1538-7445.AM2018-2515
Published: 01 July 2018
View article titled, Abstract 2515: Aberrant expression of CSF1R in melanoma is driven through an endogenous viral promoter and it contributes to malignant growth and BRAF-inhibitor resistance
Journal Articles

Abstract 3332: Aberrant expression of CSF1R in melanoma is driven through an endogenous viral promoter and it contributes to malignant growth and the acquisition of resistance against BRAF inhibition

Orsolya Giricz, Yongkai Mo, Caroline Y. Hu, Yiting Yu, Kith Pradhan, Matthias Bartenstein, Nandini Ramachandra, Veronika Polishchuck, Kimberly B. Dahlman, Tushar Bhagat, Hoa Nguyen, Bernice Matusow, Rafe Shellooe, Elizabeth Burton, Paraic Kenny, John Greally, Jeffrey Sosman, Gideon Bollag, Brian West, Amit Verma
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3332.
https://doi.org/10.1158/1538-7445.AM2017-3332
Published: 01 July 2017
View article titled, Abstract 3332: Aberrant expression of CSF1R in melanoma is driven through an endogenous viral promoter and it contributes to malignant growth and the acquisition of resistance against BRAF inhibition
Journal Articles

Abstract 1885: Integrated epigenomic profiling reveals widespread demethylation in melanoma and points to the role of CSF1R-RUNX1 axis in resistance against BRAF inhibition

Orsolya Giricz, Yongkai Mo, Caroline H. Hu, Kimberly Dahlman, Nandini Ramachandra, Matthias Bartenstein, Kith Pradhan, Tushar Bhagat, Yiting Yu, Hoa Nguyen, Elizabeth Burton, Bernice Matusow, Gaston Habets, Rafe Shellooe, Gideon Bollag, Brian West, John Greally, Jeffrey Sosman, Paraic Kenny, Amit Verma
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1885.
https://doi.org/10.1158/1538-7445.AM2016-1885
Published: 15 July 2016
View article titled, Abstract 1885: Integrated epigenomic profiling reveals widespread demethylation in melanoma and points to the role of CSF1R-RUNX1 axis in resistance against BRAF inhibition
Journal Articles

Abstract PR06: Integrated epigenomic profiling reveals widespread demethylation in melanoma and reveals CSF-1 Receptor as an aberrant regulator of malignant growth and invasion

Orsolya Giricz, Yongkai Mo, Caroline Hu, Kimberly Dahlman, Sanchari Bhattacharyya, Hoa Nguyen, Bernice Matusow, Tushar Bhagat, Yiting Yu, Rafe Shellooe, Elizabeth Burton, Gaston Habets, John Greally, Kenny Paraic, Jeffrey Sosman, Gideon Bollag, Brian West, Amit Verma
Journal: Cancer Research
Cancer Res (2015) 75 (14_Supplement): PR06.
https://doi.org/10.1158/1538-7445.MEL2014-PR06
Published: 16 July 2015
View article titled, Abstract PR06: Integrated epigenomic profiling reveals widespread demethylation in melanoma and reveals CSF-1 Receptor as an aberrant regulator of malignant growth and invasion
Journal Articles

Abstract 4781: Integrated epigenomic profiling reveals widespread demethylation in melanoma and reveals CSF-1 receptor as an aberrant regulator of malignant growth and invasion

Yongkai Mo, Orsolya Giricz, Caroline H. Hu, Kimberly B. Dahlman, Sanchari Bhattacharyya, Hoa Nguyen, Bernice Matusow, Tushar Bhagat, Rafe Shellooe, Elizabeth Burton, James Tsai, Chao Zhang, Gaston Habets, Yu Shyr, John Greally, Yiting Yu, Gideon E. Bollag, Richard Stanley, Jeffrey Trent, Paraic A. Kenny, Brian L. West, Jeffrey Sosman, Amit K. Verma
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4781.
https://doi.org/10.1158/1538-7445.AM2014-4781
Published: 01 October 2014
View article titled, Abstract 4781: Integrated epigenomic profiling reveals widespread demethylation in melanoma and reveals CSF-1 receptor as an aberrant regulator of malignant growth and invasion
Journal Articles

Abstract A26: Integrated epigenomic profiling reveals widespread demethylation in melanoma, and reveals aberrant CSF-1 receptor expression as a regulator of malignant growth and invasion inhibited by PLX3397

Yongkai Mo, Orsolya Giricz, Caroline Hu, Kimberly Dahlman, Sanchari Bhattacharyya, Hoa Nguyen, Bernice Matusow, Tushar Bhagat, Yiting Yu, Rafe Shellooe, Elizabeth Burton, Gaston Habets, John Greally, Paraic Kenny, Jeffrey Sosman, Gideon Bollag, Brian L. West, Amit Verma
Journal: Cancer Research
Cancer Res (2013) 73 (3_Supplement): A26.
https://doi.org/10.1158/1538-7445.TIM2013-A26
Published: 01 May 2014
View article titled, Abstract A26: Integrated epigenomic profiling reveals widespread demethylation in melanoma, and reveals aberrant CSF-1 receptor expression as a regulator of malignant growth and invasion inhibited by PLX3397
Journal Articles

Methylome Profiling Reveals Distinct Alterations in Phenotypic and Mutational Subgroups of Myeloproliferative Neoplasms

Sangeeta Nischal, Sanchari Bhattacharyya, Maximilian Christopeit, Yiting Yu, Li Zhou, Tushar D. Bhagat, Davendra Sohal, Britta Will, Yongkai Mo, Masako Suzuki, Animesh Pardanani, Michael McDevitt, Jaroslaw P. Maciejewski, Ari M. Melnick, John M. Greally, Ulrich Steidl, Alison Moliterno, Amit Verma
Journal: Cancer Research
Cancer Res (2013) 73 (3): 1076–1085.
https://doi.org/10.1158/0008-5472.CAN-12-0735
Published: 31 January 2013
View article titled, Methylome Profiling Reveals Distinct Alterations in Phenotypic and Mutational Subgroups of Myeloproliferative Neoplasms
Open the PDF for Methylome Profiling Reveals Distinct Alterations in Phenotypic and Mutational Subgroups of Myeloproliferative Neoplasms in another window
Includes: Supplementary data
Journal Articles

Reduced SMAD7 Leads to Overactivation of TGF-β Signaling in MDS that Can Be Reversed by a Specific Inhibitor of TGF-β Receptor I Kinase

Li Zhou, Christine McMahon, Tushar Bhagat, Cristina Alencar, Yiting Yu, Melissa Fazzari, Davendra Sohal, Christoph Heuck, Krishna Gundabolu, Chun Ng, Yongkai Mo, Wa Shen, Amittha Wickrema, Guanghui Kong, Ellen Friedman, Lubomir Sokol, Giannis Mantzaris, Andrea Pellagatti, Jacqueline Boultwood, Leonidas C. Platanias, Ulrich Steidl, Lei Yan, Jonathan M. Yingling, Michael M. Lahn, Alan List, Markus Bitzer, Amit Verma
Journal: Cancer Research
Cancer Res (2011) 71 (3): 955–963.
https://doi.org/10.1158/0008-5472.CAN-10-2933
Published: 01 February 2011
View article titled, Reduced SMAD7 Leads to Overactivation of TGF-β Signaling in MDS that Can Be Reversed by a Specific Inhibitor of TGF-β Receptor I Kinase
Open the PDF for Reduced SMAD7 Leads to Overactivation of TGF-β Signaling in MDS that Can Be Reversed by a Specific Inhibitor of TGF-β Receptor I Kinase in another window
Journal Articles

High resolution epigenomic analysis of melanoma reveals that combination of aberrant DNA methylation and gene copy number alterations can contribute to oncogenesis.

Yongkai Mo, Kathy Amiri, Mark Kelley, Davendra Sohal, Li Zhou, Tushar Bhagat, Perry Pahanish, Maria Figueroa, Kenny Ye, Reid Thomas, Ari Melnick, John Greally, Jeffrey Sosman, Amit Verma
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): LB-251.
Published: 01 May 2008
View article titled, High resolution epigenomic analysis of melanoma reveals that combination of aberrant DNA methylation and gene copy number alterations can contribute to oncogenesis.