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Yonghe Li
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Journal Articles

Abstract 2702: Mutations of SPOP, FOXA1 and IDH1 are associated with prostate cancer metastasis and biochemical outcomes

Jinlu Ma, Suxia Han, Xin Sui, Wenyan Lu, Yonghe Li, Bo Xu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2702.
https://doi.org/10.1158/1538-7445.AM2017-2702
Published: 01 July 2017
View article titled, Abstract 2702: Mutations of <em>SPOP</em>, <em>FOXA1</em> and <em>IDH1</em> are associated with prostate cancer metastasis and biochemical outcomes
Journal Articles

Abstract 5173: Discovery of a series of benzimidazoles as potent Wnt/β-catenin signaling inhibitors in colorectal cancer cells

Yonghe Li, Patsy G. Oliver, Wenyan Lu, Vibha Pathak, Corinne E. Augelli-Szafran, Donald J. Buchsbaum, Mark J. Suto
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5173.
https://doi.org/10.1158/1538-7445.AM2017-5173
Published: 01 July 2017
View article titled, Abstract 5173: Discovery of a series of benzimidazoles as potent Wnt/β-catenin signaling inhibitors in colorectal cancer cells
Journal Articles

Abstract 4600: Regulation of Wnt/β-catenin signaling by Wnt co-receptor LRP6 in colorectal cancer cells

Yonghe Li, Wenyan Lu, Taj D. King
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4600.
https://doi.org/10.1158/1538-7445.AM2016-4600
Published: 15 July 2016
View article titled, Abstract 4600: Regulation of Wnt/β-catenin signaling by Wnt co-receptor LRP6 in colorectal cancer cells
Journal Articles

Abstract 1746: Discovery and evaluation of a small molecule KIFC1 inhibitor for breast cancer treatment

Wei Zhang, Ling Zhai, Wenyan Lu, Yimin Wang, Vandana V. Gupta, Indira Padmalayam, Robert J. Bostwick, Lucile White, Ross Larry, Joseph Maddry, Sam Ananthan, Mark Suto, Bo Xu, Rongbao Li, Yonghe Li
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1746.
https://doi.org/10.1158/1538-7445.AM2015-1746
Published: 01 August 2015
View article titled, Abstract 1746: Discovery and evaluation of a small molecule KIFC1 inhibitor for breast cancer treatment
Journal Articles

Abstract 4677: Niclosamide analogs for treatment of ovarian cancer

Christen L. Walters Haygood, Rebecca C. Arend, Pui-Kai Li, Yonghe Li, Chandrika Kurpad, Abhishek Gangrade, John M. Straughn, Donald Buchsbaum
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4677.
https://doi.org/10.1158/1538-7445.AM2014-4677
Published: 01 October 2014
View article titled, Abstract 4677: Niclosamide analogs for treatment of ovarian cancer
Journal Articles

Abstract 1773: Phosphodiesterase 10A: A novel target for selective inhibition of colon tumor cell growth and Wnt/β-catenin signaling

Nan Li, Kevin Lee, Yaguang Xi, Bing Zhu, Bernary D. Gary, Verónica Ramírez-Alcántara, Evrim Gurpinar, Joshua C. Canzoneri, Alexandra Fajardo, Sara Sigler, John T. Piazza, Xi Chen, Joel Andrews, Wenyan Lu, Yonghe Li, Suzanne Russo, Larry Yet, Adam B. Keeton, William E. Grizzle, Gary A. Piazza
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1773.
https://doi.org/10.1158/1538-7445.AM2014-1773
Published: 01 October 2014
View article titled, Abstract 1773: Phosphodiesterase 10A: A novel target for selective inhibition of colon tumor cell growth and Wnt/β-catenin signaling
Journal Articles

Abstract 865: Inhibition of Wnt co-receptor LRP6 sensitizes basal-like breast cancer stem cells to TRA-8 anti-DR5 monoclonal antibody.

Angelina I. Londono-Joshi, Rebecca C. Arend, Laura Aristizabal, Yonghe Li, Wenyan Lu, Rajeev S. Samant, Brandon J. Metge, Andres Forero, Tong Zhou, Albert F. LoBuglio, Donald J. Buchsbaum
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 865.
https://doi.org/10.1158/1538-7445.AM2013-865
Published: 15 April 2013
View article titled, Abstract 865: Inhibition of Wnt co-receptor LRP6 sensitizes basal-like breast cancer stem cells to TRA-8 anti-DR5 monoclonal antibody.
Journal Articles

Abstract 2179: Wnt pathway inhibition by niclosamide: a therapeutic target for ovarian cancer.

Rebecca C. Arend, Angelina I. Londoño-Joshi, Yonghe Li, Wenyan Lu, Rajeev S. Samant, Brandon J. Metge, J. Michael Straughn, Donald J. Buchsbaum
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2179.
https://doi.org/10.1158/1538-7445.AM2013-2179
Published: 15 April 2013
View article titled, Abstract 2179: Wnt pathway inhibition by niclosamide: a therapeutic target for ovarian cancer.
Journal Articles

Abstract 500: Role of R-spondin4 in Wnt/β-catenin signaling and cell proliferation in breast cancer.

Wenyan Lu, Cuihong Lin, Taj K. King, Yonghe Li
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 500.
https://doi.org/10.1158/1538-7445.AM2013-500
Published: 15 April 2013
View article titled, Abstract 500: Role of R-spondin4 in Wnt/β-catenin signaling and cell proliferation in breast cancer.
Journal Articles

Abstract 3659: Next generation sulindac.

Nan Li, Yaguang Xi, Heather N. Tinsley, Evrim Gurpinar, Bernard D. Gary, Bing Zhu, Yonghe Li, Adam B. Keeton, William E. Grizzle, Gary A. Piazza
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3659.
https://doi.org/10.1158/1538-7445.AM2013-3659
Published: 15 April 2013
View article titled, Abstract 3659: Next generation sulindac.
Journal Articles

Abstract 1853: PDE5 suppression selectively induces apoptosis of human breast tumor cells and attenuates Wnt/β-catenin mediated transcription

Heather N. Tinsley, Adam B. Keeton, Wenyan Lu, Yonghe Li, Gary A. Piazza
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1853.
https://doi.org/10.1158/1538-7445.AM2011-1853
Published: 15 April 2011
View article titled, Abstract 1853: PDE5 suppression selectively induces apoptosis of human breast tumor cells and attenuates Wnt/β-catenin mediated transcription
Journal Articles

Abstract 1053: Mouse Kremen 1 negatively regulates Wnt/β-catenin signaling in human breast cancer MDA-MB-231 cells

Taj King, Yonghe Li
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1053.
https://doi.org/10.1158/1538-7445.AM2011-1053
Published: 15 April 2011
View article titled, Abstract 1053: Mouse Kremen 1 negatively regulates Wnt/β-catenin signaling in human breast cancer MDA-MB-231 cells
Journal Articles

Abstract 3707: Sulindac sulfide inhibits growth and induces apoptosis of human colon tumor cells by a cGMP-dependent pathway leading to suppression of β-catenin transcription activity

Nan Li, Heather Tinsley, Jason Whitt, Bernard Gary, Wenyan Lu, Yonghe Li, Adam Keeton, Gary Piazza
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3707.
https://doi.org/10.1158/1538-7445.AM2011-3707
Published: 15 April 2011
View article titled, Abstract 3707: Sulindac sulfide inhibits growth and induces apoptosis of human colon tumor cells by a cGMP-dependent pathway leading to suppression of β-catenin transcription activity
Journal Articles

Abstract #2986: In vivo inhibition of colon tumor cell growth in the HT-29 xenograft model by SRI 21009: A novel sulindac derivative that potently induces apoptosis but does not inhibit cyclooxygenases

Gary Piazza, Adam Keeton, Bernard Gary, Heather Tinsley, Jason Whitt, Meghan Knight, Bini Mattew, Lori Coward, Greg Gorman, Yonghe Li, Judith Hobrath, Yulia Maxuitenko, Robert Reynolds
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2986.
Published: 01 May 2009
View article titled, Abstract #2986: <em>In vivo</em> inhibition of colon tumor cell growth in the HT-29 xenograft model by SRI 21009: A novel sulindac derivative that potently induces apoptosis but does not inhibit cyclooxygenases
Journal Articles

Low-Density Lipoprotein Receptor-Related Protein 1 Promotes Cancer Cell Migration and Invasion by Inducing the Expression of Matrix Metalloproteinases 2 and 9

Heesang Song, Yonghe Li, Jiyeon Lee, Alan L. Schwartz, Guojun Bu
Journal: Cancer Research
Cancer Res (2009) 69 (3): 879–886.
https://doi.org/10.1158/0008-5472.CAN-08-3379
Published: 29 January 2009
View article titled, Low-Density Lipoprotein Receptor-Related Protein 1 Promotes Cancer Cell Migration and Invasion by Inducing the Expression of Matrix Metalloproteinases 2 and 9
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Includes: Multimedia, Supplementary data
Journal Articles

Repression of Wnt signaling inhibits prostate cancer cell proliferation

Wenyan Lu, Heather Tinsley, Zhican Qu, Gary Piazza, Yonghe Li
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2342.
Published: 01 May 2008
View article titled, Repression of Wnt signaling inhibits prostate cancer cell proliferation
Journal Articles

High throughout screening for Wnt signaling inhibitors

Wenyan Lu, John D. Greenwood, Clinton Maddox, Lakshmi Reddy, Sara McKellip, Tan Wang, Lynn Rasmussen, E. Lucile White, Krister Wennerberg, Yonghe Li
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1268.
Published: 01 May 2008
View article titled, High throughout screening for Wnt signaling inhibitors
Journal Articles

Opposing roles of Dkk1 in LRP6 stabilization and Wnt signaling: implication for Wnt ligand-induced LRP6 down-regulation

Yonghe Li, Wenyan Lu, Guojun Bu
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4385.
Published: 01 May 2007
View article titled, Opposing roles of Dkk1 in LRP6 stabilization and Wnt signaling: implication for Wnt ligand-induced LRP6 down-regulation