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Journal Articles

Abstract 1209: Tumor informed circulating tumor DNA monitoring for early treatment response and survival outcomes on trastuzumab + pertuzumab

Razelle Kurzrock, Merrida Childress, Wenshu Li, Anna Muse, Julia Malato, Yong Wang, Minetta Liu, Alexey Aleshin, Richard S. Wang, Julia Thierauf, Christopher J. Sweeney, John Hainsworth, Tania Szado, Amanda Young, Katja Schulze, David Spigel, Funda Meric-Bernstam, Charles Swanton, Howard A. Burris
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1209.
https://doi.org/10.1158/1538-7445.AM2024-1209
Published: 22 March 2024
View article titled, Abstract 1209: Tumor informed circulating tumor DNA monitoring for early treatment response and survival outcomes on trastuzumab + pertuzumab
Journal Articles

Fructose Metabolism in Tumor Endothelial Cells Promotes Angiogenesis by Activating AMPK Signaling and Mitochondrial Respiration

Jian-Hong Fang, Jie-Ying Chen, Jia-Lin Zheng, Hui-Xian Zeng, Jun-Guang Chen, Chen-Hui Wu, Jia-Li Cai, Zhi-Yong Wang, Shi-Mei Zhuang
Journal: Cancer Research
Cancer Res (2023) 83 (8): 1249–1263.
https://doi.org/10.1158/0008-5472.CAN-22-1844
Published: 14 April 2023
View article titled, Fructose Metabolism in Tumor Endothelial Cells Promotes Angiogenesis by Activating AMPK Signaling and Mitochondrial Respiration
Open the PDF for Fructose Metabolism in Tumor Endothelial Cells Promotes Angiogenesis by Activating AMPK Signaling and Mitochondrial Respiration in another window
Includes: Supplementary data
Journal Articles

Abstract P6-10-12: Discovery and Development of Next-Generation Estrogen Receptor Mutant Inhibitors using DNA-Encoded Chemical Library Screening

Murugesan Palaniappan, Kurt M. Bohren, Yong Wang, Damian W. Young, Suzanne A. Fuqua, Martin M. Matzuk
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P6-10-12.
https://doi.org/10.1158/1538-7445.SABCS22-P6-10-12
Published: 01 March 2023
View article titled, Abstract P6-10-12: Discovery and Development of Next-Generation Estrogen Receptor Mutant Inhibitors using DNA-Encoded Chemical Library Screening
Journal Articles

Abstract CT032: Activity and safety of alectinib for ALK-altered solid tumors from MyPathway

Charles Swanton, Claire F. Friedman, Christopher J. Sweeney, Funda Meric-Bernstam, David Spigel, Ron Bose, Howard Burris, Walter C. Darbonne, Julia Malato, Jonathan Levy, Yong Wang, Tania Szado, Katja Schulze, John Hainsworth, Razelle Kurzrock
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT032.
https://doi.org/10.1158/1538-7445.AM2022-CT032
Published: 15 June 2022
View article titled, Abstract CT032: Activity and safety of alectinib for ALK-altered solid tumors from MyPathway
Journal Articles

EIF4A3-Induced circARHGAP29 Promotes Aerobic Glycolysis in Docetaxel-Resistant Prostate Cancer through IGF2BP2/c-Myc/LDHA Signaling

Xingkang Jiang, Shanqi Guo, Shuo Wang, Yangyi Zhang, Haojie Chen, Yong Wang, Ranlu Liu, Yuanjie Niu, Yong Xu
Journal: Cancer Research
Cancer Res (2022) 82 (5): 831–845.
https://doi.org/10.1158/0008-5472.CAN-21-2988
Published: 03 March 2022
View article titled, EIF4A3-Induced circARHGAP29 Promotes Aerobic Glycolysis in Docetaxel-Resistant Prostate Cancer through IGF2BP2/c-Myc/LDHA Signaling
Open the PDF for EIF4A3-Induced circARHGAP29 Promotes Aerobic Glycolysis in Docetaxel-Resistant Prostate Cancer through IGF2BP2/c-Myc/LDHA Signaling in another window
Includes: Supplementary data
Journal Articles

Abstract LB012: Efficacy of atezolizumab in the treatment of solid tumors with high tumor mutational burden (TMB): A MyPathway study cohort

John Hainsworth, Claire F. Friedman, Razelle Kurzrock, David R. Spigel, Howard Burris, Christopher J. Sweeney, Funda Meric-Bernstam, Yong Wang, Jonathan Levy, David Shames, Katja Schulze, Arisha Patel, Charles Swanton
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB012.
https://doi.org/10.1158/1538-7445.AM2021-LB012
Published: 01 July 2021
View article titled, Abstract LB012: Efficacy of atezolizumab in the treatment of solid tumors with high tumor mutational burden (TMB): A MyPathway study cohort
Journal Articles

ZMYND8 Expression in Breast Cancer Cells Blocks T-Lymphocyte Surveillance to Promote Tumor Growth

Yong Wang, Maowu Luo, Yan Chen, Yijie Wang, Bo Zhang, Zhenhua Ren, Lei Bao, Yanan Wang, Jennifer E. Wang, Yang-Xin Fu, Weibo Luo, Yingfei Wang
Journal: Cancer Research
Cancer Res (2021) 81 (1): 174–186.
https://doi.org/10.1158/0008-5472.CAN-20-1710
Published: 04 January 2021
View article titled, ZMYND8 Expression in Breast Cancer Cells Blocks T-Lymphocyte Surveillance to Promote Tumor Growth
Open the PDF for ZMYND8 Expression in Breast Cancer Cells Blocks T-Lymphocyte Surveillance to Promote Tumor Growth in another window
Includes: Supplementary data
Journal Articles

Abstract 2501: Delineating mutational lineages with single cell DNA sequencing using multi-patient specific panels

Jake Leighton, Min Hu, Alexander Davis, Emi Sei, Yong Wang, Nicholas Navin
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2501.
https://doi.org/10.1158/1538-7445.AM2020-2501
Published: 15 August 2020
View article titled, Abstract 2501: Delineating mutational lineages with single cell DNA sequencing using multi-patient specific panels
Journal Articles

Abstract 1711: Mechanical strain induces phenotypic changes in breast cancer cells and promotes immunosuppression in the tumor microenvironment

Yong Wang, Kayla F. Goliwas, Paige E. Severino, Kenneth Hough, Derek Van Vessem, Hong Wang, Sultan Tousif, Roy P. Koomullil, Andra R. Frost, Selvarangan Ponnazhagen, Joel L. Berry, Jessy S. Deshane
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1711.
https://doi.org/10.1158/1538-7445.AM2020-1711
Published: 15 August 2020
View article titled, Abstract 1711: Mechanical strain induces phenotypic changes in breast cancer cells and promotes immunosuppression in the tumor microenvironment
Journal Articles

Abstract B23: Engineered three-dimensional lung tumor mimics maintain tissue heterogeneity allowing for investigation of tumor-stromal interactions

Kayla F. Goliwas, Yong Wang, Joel L. Berry, Victor J. Thannickal, James M. Donahue, Jessy S. Deshane
Journal: Cancer Research
Cancer Res (2020) 80 (11_Supplement): B23.
https://doi.org/10.1158/1538-7445.CAMODELS2020-B23
Published: 02 June 2020
View article titled, Abstract B23: Engineered three-dimensional lung tumor mimics maintain tissue heterogeneity allowing for investigation of tumor-stromal interactions
Journal Articles

Abstract 1177: Mechanical strain induces phenotypic changes in breast cancer cells and promotes immunosuppression in the tumor microenvironment

Yong Wang, Paige E. Severino, Kayla Goliwas, Kenneth Hough, Derek Van Vessem, Hong Wang, Andra R. Frost, Selvarangan Ponnazhagen, Joel L. Berry, Jessy S. Deshane
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1177.
https://doi.org/10.1158/1538-7445.AM2019-1177
Published: 01 July 2019
View article titled, Abstract 1177: Mechanical strain induces phenotypic changes in breast cancer cells and promotes immunosuppression in the tumor microenvironment
Journal Articles

Abstract 5797: BET inhibitor synthetic lethality in malignant peripheral nerve sheath tumors

Jonathan M. Cooper, Amish J. Patel, Zhiguo Chen, Chung-Ping Liao, Kun Chen, Yong Wang, Lu Q. Le
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5797.
https://doi.org/10.1158/1538-7445.AM2018-5797
Published: 01 July 2018
View article titled, Abstract 5797: BET inhibitor synthetic lethality in malignant peripheral nerve sheath tumors
Journal Articles

Abstract 5453: Novel pan-PI3K inhibitor WX008 demonstrates significant antitumor efficacy in three xenograft tumor models

Tao Yu, Lingwei Kong, Yong Wang, Peipei Jiang, Zhe min Rong, Chang jun Wang, Jing jie Huang, Dan Yao, Yu xin Qin, Cheng de Wu, Shu hui Chen, Xin Tian, Fei Liu, Ping Dong, Zhi Lin Chen
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5453.
https://doi.org/10.1158/1538-7445.AM2018-5453
Published: 01 July 2018
View article titled, Abstract 5453: Novel pan-PI3K inhibitor WX008 demonstrates significant antitumor efficacy in three xenograft tumor models
Journal Articles

Abstract 2371: Multi-cell phylogenetic inference of copy number evolution in breast cancer

Alexander J. Davis, Ruli Gao, Emi Sei, Pei-Ching Tsai, Anna Casasent, Amy Zhang, Xiuqing Shi, Yong Wang, Jill Waters, Funda Meric-Bernstam, Mary Edgerton, Nicholas Navin
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2371.
https://doi.org/10.1158/1538-7445.AM2016-2371
Published: 15 July 2016
View article titled, Abstract 2371: Multi-cell phylogenetic inference of copy number evolution in breast cancer
Journal Articles

Abstract 157: Single-cell DNA sequencing identifies a late dissemination model in metastatic colorectal cancer

Marco L. Leung, Anna Casasent, Yong Wang, Emi Sei, Nicholas Navin
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 157.
https://doi.org/10.1158/1538-7445.AM2016-157
Published: 15 July 2016
View article titled, Abstract 157: Single-cell DNA sequencing identifies a late dissemination model in metastatic colorectal cancer
Journal Articles

Abstract 2375: Multiclonal invasion in breast cancer identified by single cell DNA sequencing

Anna K. Casasent, Annalyssa N. Long, Aislyn Schalck, Emi Sei, Ruli Gao, Alexander Davis, Yong Wang, Mary E. Edgerton, Nicholas E. Navin
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2375.
https://doi.org/10.1158/1538-7445.AM2016-2375
Published: 15 July 2016
View article titled, Abstract 2375: Multiclonal invasion in breast cancer identified by single cell DNA sequencing
Journal Articles

Abstract LB-310: Single cell genome sequencing reveals clonal stability and diversity in breast cancer

Yong Wang, Nicholas Navin, Jill Waters, Marco Leung, Anna Unruh, Xiuqing Shi, Whijae Roh, Ken Chen, Paul Scheet, Selina Vattathil, Han Liang, Asha Multani, Hong Zhang, Funda Meric-Bernstam, Franziska Michor, Rui Zhao
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-310.
https://doi.org/10.1158/1538-7445.AM2014-LB-310
Published: 01 October 2014
View article titled, Abstract LB-310: Single cell genome sequencing reveals clonal stability and diversity in breast cancer
Journal Articles

Abstract 634: Combination chemotherapy significantly reduces indoleamine 2,3-dioxygenase activity in NSCLC patients

Cara C. Schafer, Yong Wang, Anandi Sawant, Tong Huan Jin, Selvarangan Ponnazhagan, Stefan C. Grant, Jessy S. Deshane
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 634.
https://doi.org/10.1158/1538-7445.AM2014-634
Published: 01 October 2014
View article titled, Abstract 634: Combination chemotherapy significantly reduces indoleamine 2,3-dioxygenase activity in NSCLC patients
Journal Articles

Abstract 3117: BET bromodomain inhibition triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors through Bim induction

Amish J. Patel, Chung-Ping Liao, Zhiguo Chen, Chiachi Liu, Yong Wang, Lu Q. Le
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3117.
https://doi.org/10.1158/1538-7445.AM2014-3117
Published: 01 October 2014
View article titled, Abstract 3117: BET bromodomain inhibition triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors through Bim induction
Journal Articles

Abstract 5054: Inferring mutational chronology in breast cancer by deep-sequencing tumor subpopulations

Nicholas E. Navin, Yong Wang, Jill Waters, Ken Chen, Ira Hall, Ankit Malhotra, Aaron Quinlan
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5054.
https://doi.org/10.1158/1538-7445.AM2012-5054
Published: 15 April 2012
View article titled, Abstract 5054: Inferring mutational chronology in breast cancer by deep-sequencing tumor subpopulations