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Yitian Xu
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Journal Articles

Abstract PO3-26-08: Genetic modification of tumor associated macrophages using CRISPR lipid nanoparticle platform altered tumor microenvironment and induced cancer cell elimination

Fransisca Leonard, Tyler Galbraith, Nourhan Abdelfattah, Arturas Ziemys, Chihiro Hashimoto, Harlan Cook, Yitian Xu, Shu-Hsia Chen, Roberto Rosato, Kyuson Yun
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO3-26-08.
https://doi.org/10.1158/1538-7445.SABCS23-PO3-26-08
Published: 02 May 2024
View articletitled, Abstract PO3-26-08: Genetic modification of tumor associated macrophages using CRISPR lipid nanoparticle platform altered tumor microenvironment and induced cancer cell elimination
Journal Articles

Abstract PS03-08: Spatial biomechanics determines fate in breast cancer

Sara Nizzero, Maria Pelaez Soni, Gregory Zaugg, Mariam Gachechiladze, Yitian Xu, Licheng Zhang, Junjun Zheng, Brian Menegaz, Lee B Jordan, Colin A Purdie, Philip R Quinlan, Chandandeep Nagi, Karla A Sepulveda, Philipp Oertle, Tobias A Appenzeller, Marko Loparic, Zhihui Wang, Shu-Hsia Chen, Vittorio Cristini, Marija Plodinec, Alastair Thompson
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PS03-08.
https://doi.org/10.1158/1538-7445.SABCS23-PS03-08
Published: 02 May 2024
View articletitled, Abstract PS03-08: Spatial biomechanics determines fate in breast cancer
Journal Articles

Abstract 1488: Spatial characterization of the tumor microenvironment of metastatic triple-negative breast cancer

Mahak Bhargava, Jaspreet Kaur, Geetanjali Saini, Junjun Zheng, Yitian Xu, Shu-Hsia Chen, Ping-Ying Pan, Emma Rewcastle, Umay Kiraz, Emiel Adrianus Janssen, Ritu Aneja
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1488.
https://doi.org/10.1158/1538-7445.AM2024-1488
Published: 22 March 2024
View articletitled, Abstract 1488: Spatial characterization of the tumor microenvironment of metastatic triple-negative breast cancer
Journal Articles

Abstract 5185: A multimodal, spatially defined, nanomechanical signature as predictive biomarker for breast cancer outcome: A 20 year survival study

Sara Nizzero, Maria Pelaez Soni, Gregory Zaugg, Yitian Xu, Licheng Zhang, Junjun Zheng, Lee B. Jordan, Colin A. Purdie, Philip R. Quinlan, Chandandeep Nagi, Karla A. Sepulveda, Philipp Oertle, Tobias A. Appenzeller, Marko Loparic, Shu-Hsia Chen, Vittorio Cristini, Marija Plodinec, Alastair M. Thompson
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5185.
https://doi.org/10.1158/1538-7445.AM2024-5185
Published: 22 March 2024
View articletitled, Abstract 5185: A multimodal, spatially defined, nanomechanical signature as predictive biomarker for breast cancer outcome: A 20 year survival study
Journal Articles

LILRB3 Modulates Acute Myeloid Leukemia Progression and Acts as an Effective Target for CAR T-cell Therapy

Sunny Mai, Alan Hodges, Hui-Ming Chen, Jilu Zhang, Yi-Ling Wang, Yongbin Liu, Fumiko Nakatsu, Xiaoxuan Wang, Jing Fang, Yitian Xu, Vitaliy Davidov, Kyeongah Kang, Sai Ravi Pingali, Siddhartha Ganguly, Masataka Suzuki, Marina Konopleva, Brooke Prinzing, Youli Zu, Stephen Gottschalk, Yong Lu, Shu-Hsia Chen, Ping-Ying Pan
Journal: Cancer Research
Cancer Res (2023) 83 (24): 4047–4062.
https://doi.org/10.1158/0008-5472.CAN-22-2483
Published: 15 December 2023
View articletitled, LILRB3 Modulates Acute Myeloid Leukemia Progression and Acts as an Effective Target for CAR T-cell Therapy
Open the PDF for LILRB3 Modulates Acute Myeloid Leukemia Progression and Acts as an Effective Target for CAR T-cell Therapy in another window
Includes: Supplementary data
Journal Articles

Abstract PD4-04: PD4-04 A quantitative spatial analysis of microenvironmental biomarkers for breast cancer outcome

Sara Nizzero, Maria Pelaez Soni, Yitian Xu, Licheng Zhang, Junjun Zheng, Brian A. Menegaz, Lee B Jordan, Colin A Purdie, Philip R Quinlan, Chandandeep Nagi, Karla A Sepulveda, Philipp Oertle, Tobias A Appenzeller, Marko Loparic, Zhihui Wang, Shu-Hsia Chen, Vittorio Cristini, Marija Plodinec, Alastair M. Thompson
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): PD4-04.
https://doi.org/10.1158/1538-7445.SABCS22-PD4-04
Published: 01 March 2023
View articletitled, Abstract PD4-04: PD4-04 A quantitative spatial analysis of microenvironmental biomarkers for breast cancer outcome
Journal Articles

Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer

Swarnima Singh, Nigel Lee, Diego A. Pedroza, Igor L. Bado, Clark Hamor, Licheng Zhang, Sergio Aguirre, Jingyuan Hu, Yichao Shen, Yitian Xu, Yang Gao, Na Zhao, Shu-Hsia Chen, Ying-Wooi Wan, Zhandong Liu, Jeffrey T. Chang, Daniel Hollern, Charles M. Perou, Xiang H.F. Zhang, Jeffrey M. Rosen
Journal: Cancer Research
Cancer Res (2022) 82 (12): 2281–2297.
https://doi.org/10.1158/0008-5472.CAN-21-3714
Published: 15 June 2022
View articletitled, Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer
Open the PDF for Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1963: Spatial patterns of microenvironmental biomarkers drive long-term breast cancer outcome

Sara Nizzero, Licheng Zhang, Yitian Xu, Maria J. Pelaez-Soni, Prashant Dogra, Brian A. Menegaz, Lee B. Jordan, Colin A. Purdie, Philip R. Quinlan, Chandandeep Nagi, Karla A. Sepulveda, Philipp Oertle, Tobias A. Appenzeller, Shu-Hsia Chen, Marko Loparic, Zhihui Wang, Vittorio Cristini, Marija Plodinec, Alastair M. Thompson
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1963.
https://doi.org/10.1158/1538-7445.AM2022-1963
Published: 15 June 2022
View articletitled, Abstract 1963: Spatial patterns of microenvironmental biomarkers drive long-term breast cancer outcome
Journal Articles

Abstract CT175: Targeting inducible nitric oxide in a first-in-class phase 1/2 trial in triple-negative breast cancer patients diminishes M2 macrophage polarization and led to a robust clinical response

Andrew W. Chung, Kartik Anand, Polly Niravath, Nakul Gupta, Luz A. Venta, Mary R. Schwartz, Wei Qian, Yitian Xu, Licheng Zhang, Qiuying Chen, Nabeel Attarwala, John Kuhn, Tejal A. Patel, Angel Rodriguez, Anna Belcheva, Jorge Darcourt, Joe E. Ensor, Eric Bernicker, Ping-Ying Pan, Virginia Kaklamani, Shu-Hsia Chen, Jenny C. Chang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT175.
https://doi.org/10.1158/1538-7445.AM2021-CT175
Published: 01 July 2021
View articletitled, Abstract CT175: Targeting inducible nitric oxide in a first-in-class phase 1/2 trial in triple-negative breast cancer patients diminishes M2 macrophage polarization and led to a robust clinical response
Journal Articles

Abstract 2891: Chemokine-targeted models of human orthotopic colorectal cancer in immunocompetant mice

Steven M. Lipkin, Huanhuan Joyce Chen, Jian Sun, Zhiliang Huang, Harry Hou, Myra Arcilla, Nikolai Rakhilin, Daniel Joe, Jiahn Choi, Poornima Gadamsetty, Jeff Milsom, Govind Nandakumar, Randy Longman, Kathy Zhou, Robert Edwards, Kai Yuan Chen, Pengcheng Bu, Lihua Wang, Yitian Xu, Robert Munroe, Christian Abratte, Andrew Miller, Zeynep Gümüş, Michael Shuler, Nozomi Nishimura, Winfried Edelmann, Xiling Shen
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2891.
https://doi.org/10.1158/1538-7445.AM2015-2891
Published: 01 August 2015
View articletitled, Abstract 2891: Chemokine-targeted models of human orthotopic colorectal cancer in immunocompetant mice